Abstract: Sulfur chelated ruthenium compounds represented by the following formula: wherein M indicates the ruthenium metal bound to a benzylidene carbon; R represents C1-C7 alkyl group or optionally substituted aryl; X1 and X2 each independently represent halogen; Y1 and Y2 each independently denote unsubstituted or alkyl-substituted phenyl; and Z independently represents hydrogen, electron withdrawing or electron donating substituent, with m being an integer from 1 to 4, and processes and compositions related thereto.
Type:
Application
Filed:
October 30, 2009
Publication date:
May 6, 2010
Applicant:
BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
Abstract: Provided is a formulation containing amorphous or microcrystalline calcium carbonate finely interspersed with organic matter in a ratio of 10 parts of the carbonate per 1 to 3 parts of the organic matter, wherein the organic matter consists of chitin and polypeptide. The formulation is efficient in treating various pathological conditions, including proliferative diseases, neurological disorders, and musculoskeletal disorders.
Type:
Application
Filed:
October 7, 2007
Publication date:
April 22, 2010
Applicants:
BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
Abstract: A low dose rate brachytherapy seed having activity in the range between 0.5 and 10 millicurie, preferably less than 3 millicurie, comprising thulium-170 placed within a casing and at least one layer of a radiation emission modifying metal, said layer being provided either internally within the casing or on the outer surface thereof. The radiation emission modifying metal is preferably gold.
Type:
Application
Filed:
September 10, 2009
Publication date:
April 22, 2010
Applicant:
BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
Abstract: Apparatus of a grid-connected switching inverter for injecting it current into a power line comprises: (a) an electrical energy source for providing the substantially DC voltage to the apparatus; (b) a switching inverter connected to the electrical energy source for converting the substantially DC voltage of the electrical energy source to a high frequency alternating voltage; (c) a waveform generator for controlling the magnitude and shape of the alternating high frequency voltage outputted from the switching inverter by means of a control signal fed into the switching inverter; (d) an inductor connected to an output of the switching inverter for generating an alternating current from the alternating high frequency voltage, wherein the magnitude of the alternating current depends on a frequency of the alternating high frequency voltage: (e) a rectifier connected in series with the inductor for rectifying the alternating current and for outputting a rectified unipolar alternating current, wherein the rectifie
Type:
Application
Filed:
December 22, 2009
Publication date:
April 22, 2010
Applicant:
Ben-Gurion University Of The Negev Research And Development Aurthority
Abstract: Carbon nanotube reinforced polymers include a polymer and carbon nanotubes reinforcing the polymer. The carbon nanotube reinforced polymer exhibits a conductivity percolation threshold of less than 106 ?/cm at a carbon nanotube content of 1.5 wt. % and less. The polymer may be selected from a polyamide or a polystyrene based polymer. In certain embodiments, the carbon nanotube content is between 0.1 to 1.5 wt. %, and the reinforced polymer will have a percolation threshold at a carbon nanotube content of less than 0.5 wt. %.
Type:
Application
Filed:
May 6, 2009
Publication date:
March 25, 2010
Applicants:
STICHTING DUTCH POLYMER INSTITUTE, BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
Inventors:
Cornelis E. KONING, Oren REGEV, Joachim LOOS
Abstract: The invention provides a process for improving the antifouling properties and for increasing the selectivity of commercial composite polyamide nanofiltration (NF) and reverse osmosis (RO) membranes comprising circulating a low concentration of water soluble monomers and an initiating redox couple in an aqueous solvent, without transverse pressure over the surface of the membrane thereby effecting a free-radical graft polymerization on the surface of the membrane.
Type:
Grant
Filed:
September 4, 2005
Date of Patent:
March 16, 2010
Assignee:
Ben Gurion University of the Negev Research and Development Authority
Inventors:
Sophia Belfer, Rosalia Fainstein, Luba Kesselman, Charles Linder
Abstract: A method is provided for manufacturing a liquid nitrogen fertilizer from organic wastes and manures, in which nitrogen is extracted as an aqueous ammonia, and further concentrated, and eventually converted to nitrate in a biological reactor. The method may utilize nitrogen rich organic wastes and manures, such as wastewater sludge, slaughter house wastes, broiler layer, and guano, and it is especially suitable for providing a nitrogen fertilizer in organic farming.
Type:
Grant
Filed:
November 7, 2006
Date of Patent:
March 9, 2010
Assignee:
Ben Gurion University of the Negev Research and Development Authority
Abstract: The invention relates to the use of 2,2,3,3 tetramethylcyclopropane carboxylic acid derivative compounds for the preparation of a medicament for treating a psychiatric disorder preferably a bipolar disorder. The invention additionally relates to the use of the compounds for the preparation of an inhibitor of MIP synthase and to a pharmaceutical composition comprising the compounds for treating a psychiatric disorder. A method for treating a psychiatric disorder preferably a bipolar disorder and a method for inhibiting an enzyme having MIP synthase activity is provided.
Type:
Application
Filed:
May 27, 2004
Publication date:
February 25, 2010
Applicants:
Yissum Research Development Co. of the Hebrew University of Jerusalem, Ben Gurion University of the Negev Research and Development Authority
Inventors:
Meir BIALER, Boris YAGEN, Haim BELMAKER, Galila AGAM, Galit SHALTIEL
Abstract: A photosensitive pixel includes a photosensor and an externally loadable flag. The photosensor outputs a signal indicative of an intensity of incident light. The externally loadable flag indicates the pixel reset state, and is preferably stored in an in-pixel memory. Pixel reset logic resets the photosensor in accordance with the reset state and an externally applied reset signal.
Type:
Application
Filed:
November 19, 2007
Publication date:
February 4, 2010
Applicant:
Ben Gurion University of the Negev Research and Development Authority
Inventors:
Alexander Belenky, Alexander Fish, Orly Yadid-Pecht
Abstract: A two-stage treatment process, for the treatment of nitrate rich water, particularly aquaculture pond water, wherein in the first stage a degassing chamber is used for removing dissolved oxygen from a stream of water flowing out of the aquaculture system, and in the second stage the stream of water obtained from said degassing chamber is flown into a denitrifying biofilter comprising a biofilter media which functions as a biological growth media and as a carbon source, wherein said denitrifying biofilter is capable of biologically reducing both nitrate and nitrite compounds into nitrogen gas.
Type:
Application
Filed:
May 31, 2007
Publication date:
January 21, 2010
Applicant:
BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY
Inventors:
Alon Singer, Shmuel Parnes, Asher Brener, Amir Sagi
Abstract: The present invention relates to the field of tissue engineering and more specifically to amphiphilic peptides and peptide matrices thereof useful in vitro and in situ biomineralization and inducing bone repair. The present invention provides peptides, which are useful in hydrogels and other pharmaceutical compositions, and methods and kits of use for bone repair and promotion of biomineralization. Certain hydrogels according to the invention comprise cells within or adhered to the peptide matrix.
Type:
Application
Filed:
June 19, 2007
Publication date:
January 21, 2010
Applicant:
BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DE
Abstract: The present invention provides bioconjugates comprising a sulfated polysaccharide such as alginate sulfate and hyaluronan sulfate and at least one bioactive polypeptide capable of binding a sulfate group of said sulfated polysaccharide. The bioactive polypeptide can be a heparin-binding polypeptide and/or a positively-charged polypeptide. Also, provided are delivery systems and methods for sustained release of said bioactive polypeptide(s) using said bioconjugates.
Type:
Grant
Filed:
January 5, 2007
Date of Patent:
January 5, 2010
Assignee:
Ben-Gurion University of the Negev Research and Development Authority
Abstract: An integrated ion chip for a large scale quantum device of interconnected ion (or other charged particles) traps each holding a small number of particles for a finite period of time, in a preferred embodiment using sapphire as the substrate, having an internal trapping, translation, and quantum manipulation zones and having a first set of electrodes and a second set of electrodes for trapping ions and for quantum manipulations, in a preferred embodiment using silicon carbide (and materials of similar characteristics) as a core structure material, and utilizing unique fabrication processes using micromachining and thin film techniques.
Type:
Application
Filed:
May 1, 2008
Publication date:
December 31, 2009
Applicant:
Ben Gurion University of The Negev Research And Development Authority
Inventors:
Ron FOLMAN, Alexander Fayer, Benny Hadad, Amir Ben-Tal, Amit Ben-Kish
Abstract: The invention provides a rapid and economical process for manufacturing a transparent, spinel based ceramic. A transparent body of sintered magnesium aluminate spinel having excellent optical and mechanical properties is provided in a single-stage thermal process.
Type:
Application
Filed:
May 27, 2009
Publication date:
December 3, 2009
Applicant:
Ben-Gurion University of the Negev Research and Development Authority
Inventors:
Nahum Frage, Moshe Dariel, Shai Meir, Sergei Kalabuchov
Abstract: An antenna array and signal preprocessing apparatus and method. The antenna array is a quadrature polarized array having two orthogonal electric dipoles and two orthogonal magnetic dipoles. The preprocessor is for preprocessing signals from the antenna, for obtaining spatial spectrum information for signal source location. The preprocessor comprises an autocorrelator, connected after said input, for forming signal autocorrelation matrices for each element, and an smoother, connected after said autocorrelator, for averaging said autocorrelation matrices, thereby to form a sample covariance matrix suitable for use in a Eigenstructure based estimator for estimating source localization.
Type:
Grant
Filed:
November 17, 2003
Date of Patent:
November 17, 2009
Assignee:
Ben Gurion University of the Negev Research and Development Authority
Inventors:
Dayan Rahamim, Reuven Shavit, Joseph Tabrikian
Abstract: A new method and system for Optical Code Division Multiple Access (OCDMA) transmission, in which channel selection and rejection are based on dynamic self-heterodyne filtering using differential time delays applied to the data-modulated signals to code and decode the transmissions in each channel. Mach-Zender Interferometers having characteristic delays between their arms are a simple way of performing this coding and decoding. The technique enables the use of narrow linewidth sources and low spectrum spreading. Consequently this technique can be used in next-generation all-optical dynamic networks allowing bandwidth sharing on the one hand, while at the same time eliminating the need for network management and optical switching. Preliminary theoretical calculations predict the system support of up to 15 channels at a data rate of 1 GHz.
Type:
Application
Filed:
March 10, 2006
Publication date:
October 29, 2009
Applicant:
Ben-Gurion University of the Negev - Research and Development Authority
Abstract: Disclosed is a novel net member for supporting one or more cell constructs in the culture chamber of a bioreactor, which comprises an array of impermeable pyramidal elements protruding from the face thereof, wherein each of the corners of the base of each of said impermeable pyramidal elements comprises a circular opening. This net member provides for uniform and unobstructed flow of culture medium through 3D cell constructs in culture. Also disclosed are a bioreactor and bioreactor system incorporating said net member. The bioreactor and bioreactor system may be used in the bioproduction of therapeutic proteins and stem cell expansion.
Type:
Grant
Filed:
December 9, 2004
Date of Patent:
October 27, 2009
Assignee:
Ben Gurion University of the Negev Research and Development Authority
Abstract: A capsule for high dose rate brachytherapy, wherein the capsule comprises within its interior space thulium-170, and further comprises at least one layer of a radiation emission modifying metal (e.g., gold), wherein said layer is provided either internally within the capsule or on the outer surface thereof.
Type:
Application
Filed:
April 1, 2009
Publication date:
October 1, 2009
Applicant:
Ben-Gurion University of the Negev Research and Development Authority
Abstract: A method of generating embryoid bodies is provided. The method comprising culturing undifferentiated embryonic stem cells on a three dimensional scaffold under conditions suitable for formation of embryoid bodies, thereby generating the embryoid bodies.
Type:
Application
Filed:
August 10, 2005
Publication date:
September 24, 2009
Applicants:
Technion Research & Development Foundation Ltd., Ben Gurion University of the Negev Research and Development Authority
Inventors:
Sharon Gerecht, Smadar Cohen, Joseph Itskovitz-Eldor
Abstract: Apparatus for detection of human falls, comprises: an acceleration detector, for detecting vibration events, typically placed on a floor, a microphone, located in association with the acceleration detector for detection of corresponding sound events, and a classification unit to classify concurrent events from the microphone and the acceleration detector, thereby to determine whether a human fall is indicated. If the event appears to be a human fall, then an alarm is raised.
Type:
Application
Filed:
January 28, 2009
Publication date:
September 10, 2009
Applicants:
Ramot At Tel Aviv University Ltd., Ben Gurion University of the Negev Research and Development Authority
Inventors:
Israel Gannot, Dimitry Litvak, Yaniv Zigel