Patents Assigned to Biolog
  • Patent number: 9274101
    Abstract: The present invention relates to growing and testing eukaryotic cells (e.g., animal or plant cells) in a multi-test format. In particular, the present invention provides methods and kits for obtaining a complex metabolic profile of animal cells. In addition, the present invention provides tools for assaying the effects of candidate compounds (e.g., hormones) on substrate utilization by mammalian cells.
    Type: Grant
    Filed: May 5, 2006
    Date of Patent: March 1, 2016
    Assignee: BIOLOG, Inc.
    Inventors: Barry Bochner, Larry Wiater
  • Patent number: 9275262
    Abstract: A qualification method for a container provided with an RFID tag comprising the following steps when the container is stored in a storage enclosure comprising a sensor suitable for measuring the temperature within the enclosure and an RFID reader: a/ radiofrequency transmission by reader of a message comprising a value representative of a temperature measurement in the enclosure; step a/ being reiterated after each measurement moment of a plurality of predetermined successive measurement moments; b/ storage, by the RFID tag of the container, of the value included in said message received, the memory of the RFID tag comprising successively stored temperature values each associated with a distinct determined measurement moment; c/ qualification or disqualification of the container as a function of a comparison between the number of temperature values stored for the container and the number of said determined measurement moments.
    Type: Grant
    Filed: March 27, 2013
    Date of Patent: March 1, 2016
    Assignee: BIOLOG
    Inventors: Jean-Claude Mongrenier, François Dussaux
  • Publication number: 20140088033
    Abstract: The present invention relates to novel boranophosphate analogues of cyclic nucleotides. The invention further relates to the use of such compounds as reagents for signal transduction research or as modulators of cyclic nucleotide-regulated binding proteins and isoenzymes thereof, and/or as hydrolysis- and oxidation-resistant ligands for affinity chromatography, for antibody production or for diagnostic applications e.g. on chip surfaces and/or as additive for organ transplantation storage solutions.
    Type: Application
    Filed: March 27, 2012
    Publication date: March 27, 2014
    Applicant: BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH
    Inventor: Hans-Gottfried Genieser
  • Patent number: 7776601
    Abstract: The invention concerns a method which consists in determining ageing an ageing index of a blood bag (11, 62), to determine whether the blood bag is or not suitable for transfusion to a patient. The ageing index is calculated by connecting a silicon chip provided with a loop antenna integral with the blood bag (11, 62) with an electronic communication device (2, 8, 17, 12, 20, 24), itself equipped with a loop antenna, connected to a computer (9, 13) containing appropriate computing software elements. Said ageing index is regularly calculated at the blood transfusion center (16) from the sample (1), until it is removed from storage (7) to be sent to the health-care institution (18) and to the operating theatre (19).
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: August 17, 2010
    Assignee: Biolog
    Inventors: Antoine De Gaulle, Jean-Claude Mongrenier
  • Patent number: 7575936
    Abstract: Method for enhancing the reliability of the traceability of blood samples resulting from collection of whole blood in a mother blood bag using sampling kits, whose contents vary depending on the blood products needed and statutory regulations, and which are mainly composed of bags connected to each other by tubes and incorporating at least one filtration unit. Each bag includes an electronic chip capable of memorising and exchanging information with an electronic communication device. This abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: August 18, 2009
    Assignee: Biolog
    Inventors: Antoine De Gaulle, Jean-Claude Mongrenier
  • Patent number: 7209045
    Abstract: Method of monitoring a blood bag, the method including monitoring a maximum allowed time dT that the blood bag may be kept outside a controlled-atmosphere enclosure and an expiration date stored in an electronic chip fixed to the blood bag. The method further including indicating whether the blood bag may be transfused to a patient when the time dT and the expiration date have not expired. The instant abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: April 24, 2007
    Assignee: Biolog S.A.
    Inventors: Antoine De Gaulle, Jean-Claude Mongrenier
  • Publication number: 20060286627
    Abstract: The present invention relates to growing and testing eukaryotic cells (e.g., animal or plant cells) in a multi-test format. In particular, the present invention provides methods and kits for obtaining a complex metabolic profile of animal cells. In addition, the present invention provides tools for assaying the effects of candidate compounds (e.g., hormones) on substrate utilization by mammalian cells.
    Type: Application
    Filed: May 5, 2006
    Publication date: December 21, 2006
    Applicant: Biolog Inc.
    Inventors: Barry Bochner, Larry Wiater
  • Publication number: 20050260558
    Abstract: The present invention relates to growing and testing any cell type in a multitest format. The present invention is suited for the characterization of microorganisms, as well as animal and plant cells. The present invention is also particularly suited for analysis of phenotypic differences between strains of organisms, including cultures that have been designated as the same genus and species. The present invention is also suited for the analysis of phenotypic differences between cell lines. In some embodiments, a gel forming matrix is used. The present invention provides methods and compositions for the phenotypic analysis and comparison of eukaryotic, as well as prokaryotic cells. The present invention further provides novel methods and compositions for testing the effect(s) of biologically active chemicals on various cells.
    Type: Application
    Filed: July 27, 2005
    Publication date: November 24, 2005
    Applicant: Biolog Inc.
    Inventors: Barry Bochner, Amy Morgan
  • Patent number: 6727076
    Abstract: The present invention relates to growing and testing microorganisms in a multitest format which utilizes a gel forming matrix for the rapid screening of clinical and environmental cultures. The present invention is suited for the characterization of commonly encountered microorganisms (e.g., E. coli, S. aureus, etc.), as well as commercially and industrially important organisms from various and diverse environments (e.g., the present invention is particularly suited for the growth and characterization of the actinomycetes and fungi). The present invention is also particularly suited for comparative analysis of phenotypic differences between cell types, including strains of microorganisms that have been designated as the same genus and species, as well as other cell types (e.g., mammalian, insect, and plant cells).
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: April 27, 2004
    Assignee: Biolog, Inc.
    Inventor: Barry Bochner
  • Patent number: 6696239
    Abstract: The present invention relates to using multitest panels to improve the effectiveness, throughput, and efficiency of testing and commercial development of biologically active compounds, in particular those useful in human, animal, and plant health. In particular, the present invention provides phenotype microarrays suitable for testing biologically active compounds for their potential application in clinical, veterinary, and plant health.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: February 24, 2004
    Assignee: Biolog, Inc.
    Inventor: Barry Bochner
  • Patent number: 6686173
    Abstract: The present invention relates to growing and testing microorganisms in a multitest format which utilizes a gel forming matrix for the rapid screening of clinical and environmental cultures. The present invention is suited for the characterization of commonly encountered microorganisms (e.g., E. coli, S. aureus, etc.), as well as commercially and industrially important organisms from various and diverse environments (e.g., the present invention is particularly suited for the growth and characterization of the actinomycetes and fungi). The present invention is also particularly suited for comparative analysis of phenotypic differences between cell types, including strains of microorganisms that have been designated as the same genus and species, as well as other cell types (e.g., mammalian, insect, and plant cells).
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: February 3, 2004
    Assignee: Biolog, Inc.
    Inventors: Barry Bochner, Eugenia Panomitros
  • Publication number: 20030162164
    Abstract: The present invention relates to growing and testing any cell type in a multitest format. The present invention is suited for the characterization of microorganisms, as well as animal and plant cells. The present invention is also particularly suited for analysis of phenotypic differences between strains of organisms, including cultures that have been designated as the same genus and species. The present invention is also suited for the analysis of phenotypic differences between cell lines. In some embodiments, a gel forming matrix is used. The present invention provides methods and compositions for the phenotypic analysis and comparison of eukaryotic, as well as prokaryotic cells. The present invention further provides novel methods and compositions for testing the effect(s) of biologically active chemicals on various cells.
    Type: Application
    Filed: April 19, 2002
    Publication date: August 28, 2003
    Applicant: BIOLOG, INC.
    Inventors: Barry Bochner, Amy Morgan
  • Publication number: 20030148413
    Abstract: The present invention relates to growing and testing microorganisms in a multitest format which utilizes a gel forming matrix for the rapid screening of clinical and environmental cultures. The present invention is suited for the characterization of commonly encountered microorganisms (e.g., E. coli, S. aureus, etc.), as well as commercially and industrially important organisms from various and diverse environments (e.g., the present invention is particularly suited for the growth and characterization of the actinomycetes and fungi). The present invention is also particularly suited for comparative analysis of phenotypic differences between cell types, including strains of microorganisms that have been designated as the same genus and species, as well as other cell types (e.g., mammalian, insect, and plant cells).
    Type: Application
    Filed: August 23, 2002
    Publication date: August 7, 2003
    Applicant: BIOLOG, INC.
    Inventor: Barry Bochner
  • Patent number: 6472201
    Abstract: The present invention relates to growing and testing microorganisms in a multitest format which utilizes a gel forming matrix for the rapid screening of clinical and environmental cultures. The present invention is suited for the characterization of commonly encountered microorganisms (e.g., E. coli, S. aureus, etc.), as well as commercially and industrially important organisms from various and diverse environments (e.g., the present invention is particularly suited for the growth and characterization of the actinomycetes and fungi). The present invention is also particularly suited for comparative analysis of phenotypic differences between cell types, including strains of microorganisms that have been designated as the same genus and species, as well as other cell types (e.g., mammalian, insect, and plant cells).
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: October 29, 2002
    Assignee: Biolog, Inc.
    Inventors: Barry Bochner, Eugenia Panomitros
  • Patent number: 6436631
    Abstract: The present invention relates to using multitest panels to improve the effectiveness, throughput, and efficiency of testing and commercial development of biologically active compounds, in particular those useful in human, animal, and plant health. In particular, the present invention provides phenotype microarrays suitable for testing biologically active compounds for their potential application in clinical, veterinary, and plant health.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: August 20, 2002
    Assignee: Biolog, Inc.
    Inventor: Barry Bochner
  • Patent number: 6387651
    Abstract: The present invention relates to growing and testing microorganisms in a multitest format which utilizes a gel forming matrix for the rapid screening of clinical and environmental cultures. The present invention is suited for the characterization of commonly encountered microorganisms (e.g., E. coli, S. aureus, etc.), as well as commercially and industrially important organisms from various and diverse environments (e.g., the present invention is particularly suited for the growth and characterization of the actinomycetes and fungi). The present invention is also particularly suited for comparative analysis of phenotypic differences between cell types, including strains of microorganisms that have been designated as the same genus and species, as well as other cell types (e.g., mammalian, insect, and plant cells).
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: May 14, 2002
    Assignee: Biolog, Inc.
    Inventors: Barry Bochner, Eugenia Panomitros
  • Patent number: 6271022
    Abstract: The present invention provides easy-to-use, adaptable, and convenient solutions to a heretofore unmet need for instruments that can incubate and kinetically monitor assays, especially multiwell assays. In particular, the present invention finds use in monitoring assays contained within various test formats, including, but not limited to microtiter plates, miniaturized test panels (e.g., MICROCARDS™), and petri plates.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: August 7, 2001
    Assignee: Biolog, Inc.
    Inventor: Barry Bochner
  • Patent number: 6136554
    Abstract: The present invention is directed to methods and media for the growth, enrichment, isolation, and presumptive identification of enteric pathogens such as E. coli 0157:H7 and Salmonella. In particular, the organisms commonly associated with gastrointestinal infections of humans and other animals are distinguished based on their growth, colonial morphology and color. The present invention is also directed to methods and media for the growth, enrichment, isolation and presumptive identification of enteric pathogens such as E. coli 0157:H7 and Salmonella isolated from food, water, dairy, and environmental samples.
    Type: Grant
    Filed: March 17, 1997
    Date of Patent: October 24, 2000
    Assignee: Biolog, Inc.
    Inventor: Barry Bochner
  • Patent number: 6046020
    Abstract: The present invention relates to growing and testing microorganisms in which an anti-capsule compound is used in order to prevent false positive results. The present invention is suited for the characterization of commonly encountered microorganisms which commonly produce capsules (e.g., Kkebsiella, Enterobacter, Escherichia, Burkholderia, Pseudomonas, Sphingobacterium, Chryseobacterium, Bacillus, Micrococcus, Staphylococcus, Haemophilus, Neisseria, Gordona, Kytococcus, Jonesia, Rhodococcus, Corynebacterium, Streptococcus, Cellulomonas, Brevibacterium, Arcanobacterium, Tsukamurella, Acinetobacter, Cryptococcus, etc.), as well as organisms of medical, veterinary, commercial, and/or industrial importance from various and diverse environments.
    Type: Grant
    Filed: May 5, 1998
    Date of Patent: April 4, 2000
    Assignee: Biolog, Inc.
    Inventors: Barry Bochner, Amalia Franco-Buff
  • Patent number: 6046021
    Abstract: The present invention relates to growing and testing microorganisms in a multitest format which utilizes a gel forming matrix for the rapid screening of clinical and environmental cultures. The present invention is suited for the characterization of commonly encountered microorganisms (e.g., E. coli, S. aureus, etc.), as well as commercially and industrially important organisms from various and diverse environments (e.g., the present invention is particularly suited for the growth and characterization of the actinomycetes and fungi). The present invention is also particularly suited for comparative analysis of phenotypic differences between cell types, including strains of microorganisms that have been designated as the same genus and species, as well as other cell types (e.g., mammalian, insect, and plant cells).
    Type: Grant
    Filed: June 16, 1998
    Date of Patent: April 4, 2000
    Assignee: Biolog, Inc.
    Inventor: Barry Bochner