Patents Assigned to BioSensor, Inc.
-
Patent number: 11938478Abstract: Provided is a genome extraction device to which a dual chamber structure of an outer chamber and a bead chamber is applied, more particularly a genome extraction device to which the above-described dual chamber structure is applied so that the performance of dry beads vulnerable to moisture can be maintained for a long time.Type: GrantFiled: November 18, 2021Date of Patent: March 26, 2024Assignee: SD BIOSENSOR, INC.Inventors: Young-Shik Cho, Sunyoung Lee, Kwanhun Lim, In-Ae Kim, Dong-Hun Kim, Hae-Joon Park, Hyo-Lim Park
-
Patent number: 11867653Abstract: A system and method for controlled fluid handling and processing of singulated biosensors. The system includes a consumable for mounting and protecting biosensors.Type: GrantFiled: March 11, 2021Date of Patent: January 9, 2024Assignee: Monroe Biosensors, Inc.Inventors: Jason Mitchell, Bryan Witherbee, Tracey Hodge, Christopher Striemer, David Merrigan, Martin Reddin, John-Paul Griffin, John Daly
-
Publication number: 20230338011Abstract: Provided is a diagnostic kit, in which a detection device and a specimen collection tool are integrated. The diagnostic kit includes a specimen collector capable of collecting a specimen, a device including a housing and a detection strip, and a connector connecting the specimen collector with the device and moving a solution, the connector having a bar shape.Type: ApplicationFiled: March 19, 2021Publication date: October 26, 2023Applicants: BIONOTE, INC., SD BIOSENSOR, INC.Inventors: Young Shik CHO, Jung Ho KIM, Hyo Lim PARK, Dong Hyuk KIM
-
Patent number: 11795514Abstract: The invention relates to an isothermal-based dual functional oligonucleotide containing quencher and reporter dye for an isothermal nucleic acid amplification and a method for nucleic acid amplification and measurement using the same. The present invention is directed to a method capable of obviating the need for an additional oligonucleotide, in addition to four to six types of oligonucleotides for a nucleic acid amplification reaction of LAMP, detecting the amount of fluorescence according to the amplification of the nucleic acid of target gene—specific sequence for DNA and RNA, enabling the detection also after the completion of the reaction, and detecting the amount of fluorescence in real-time. Therefore, the present invention allows simultaneous multiple tests by measuring the amount of fluorescence in one tube after the completion of the reaction or in real time while varying the reporter dye according to the target gene.Type: GrantFiled: November 30, 2016Date of Patent: October 24, 2023Assignee: SD BIOSENSOR, INC.Inventors: Yoo Deok Won, Hae Joon Park, Hyo Jin Seong, Mi Ae Lim, Sun Young Lee
-
Patent number: 11638535Abstract: This disclosure relates to wireless electronics designed for use within the oral cavity to measure biological or chemical variables, including pH or analyte concentrations, and transmit the measurements. More particularly, the disclosure relates to a wearable intraoral sensor comprising sensing electronics arranged within a flexible circuit mounted onto a molar band, a wireless transmission unit coupled to the sensing electronics and configured to wirelessly transmit electrical data signals to a receiver outside of the oral cavity, and a power source operably coupled to the sensing electronics and wireless transmission unit. The wearable intraoral sensor can be installed around a tooth and continually measure and wirelessly transmit measurement data for extended periods of time without user action.Type: GrantFiled: January 22, 2019Date of Patent: May 2, 2023Assignee: UCHU BIOSENSORS, INC.Inventors: Daniel Weinstein, Saam Bozorg, Noah Hill, John R. Zebryk, Jr.
-
Patent number: 11585739Abstract: There is provided a nucleic acid extraction method using a cartridge comprising: (a) a driving part of a nucleic acid extraction device is connected to a control rod module disposed in an inner space of the upper body of a piston and a rotation control module coupled to the lower body of the piston; (b) driving the rotation control module and the control rod module, sequentially sucking sample and reagents from the plurality of chambers separated from each other into an interior space, and discharging the mixture of the interior space into the chamber of the cartridge; and (c) driving the rotation control module and the control rod module to suck the reagent inside the master mix bead chamber of the cartridge into the interior space of the piston upper body and then discharge the mixed reagent to a nucleic acid amplification module.Type: GrantFiled: December 20, 2018Date of Patent: February 21, 2023Assignee: SD BIOSENSOR, INC.Inventors: Young Shik Cho, Hyo Guen Lee, Hae Joon Park, Sun Young Lee, Kwan Hun Lim, In Ae Kim, Jae Young Kim, Hyo Lim Park, Dong Hun Kim
-
Publication number: 20230009171Abstract: Persons with sleep disordered breathing (SDB) may, or may not, recognize that they have symptoms of SDB, and/or that they may be at-risk of, or suffering certain health problems associated with SDB, including death. The disclosed Energy Conversion Monitor (ECM) sensor, when embodied, for example, in a wearable upper-armband format, has been demonstrated to be more sensitive and responsive than pulse oximetry monitoring of blood oxygen saturation as an indication of hypoxic stress induced by SDB, and is compatible with: (1) inclusion in sleep laboratory polysomnograph (PSG) testing instrumentation, (2) home-based diagnostic testing for SDB, (3) control of home-use airway therapy devices, (4) continuous remote surveillance and refinement of airway therapy, and (5) spot-check and continuous surveillance of sleep quality in the general population. The disclosed ECM also provides new measurements of physiologic stress during and following exercise.Type: ApplicationFiled: July 20, 2022Publication date: January 12, 2023Applicant: REVEAL BIOSENSORS, INC.Inventor: Guy Meredith HATCH
-
Publication number: 20220386932Abstract: Systems, methods and computer-readable media are disclosed for providing therapeutic auditory stimulation. Consistent with disclosed embodiments, a system for providing therapeutic auditory stimulation may comprise a diagnostic unit that computes an EEG spectral density of a patient and a heart rate spectral density of a patient and provides values for one or more EEG frequency bands and one or more heart rate frequency bands. The system may also comprise a therapy unit that generates, based on the provided values, one or more stimulation waveforms corresponding to one or more of the EEG frequency bands and provides the stimulation waveforms for therapeutic auditory stimulation. The stimulation waveforms may comprise audible carrier frequencies modulated by signals with frequencies that vary exponentially with time. The EEG frequency bands may comprise the delta, theta, alpha, beta 1, beta 2, and gamma EEG frequency hands.Type: ApplicationFiled: May 18, 2022Publication date: December 8, 2022Applicant: Biosensor, Inc.Inventor: Natalia IZVARINA
-
Patent number: 11506613Abstract: Provided is a fluid analysis apparatus and a method of controlling the same. The fluid analysis apparatus include an actuator provided on a part of the fluid analysis apparatus, a mounting portion on which a fluid accommodating cartridge is mounted thereon, the fluid accommodating cartridge provided with a well in which a fluid sample is accommodated, a measurement portion configured to transmit light to the fluid accommodating cartridge and detect an optical signal from the light passed through the fluid accommodating cartridge, and a controller configured to control an operation of the actuator based on the optical signal detected by the measurement portion such that the light transmitted from the measurement portion passes through a central portion of the well to perform an accurate inspection on the fluid sample.Type: GrantFiled: October 2, 2018Date of Patent: November 22, 2022Assignee: PRECISION BIOSENSOR INC.Inventors: Hong-Geun Kim, Hyun-Suk Kang, Jong Gun Lee, Jong Cheol Kim, Seung Woo Han
-
Patent number: 11426093Abstract: Persons with sleep disordered breathing (SDB) may, or may not, recognize that they have symptoms of SDB, and/or that they may be at-risk of, or suffering certain health problems associated with SDB, including death. The disclosed Energy Conversion Monitor (ECM) sensor, when embodied, for example, in a wearable upper-armband format, has been demonstrated to be more sensitive and responsive than pulse oximetry monitoring of blood oxygen saturation as an indication of hypoxic stress induced by SDB, and is compatible with: (1) inclusion in sleep laboratory polysomnograph (PSG) testing instrumentation, (2) home-based diagnostic testing for SDB, (3) control of home-use airway therapy devices, (4) continuous remote surveillance and refinement of airway therapy, and (5) spot-check and continuous surveillance of sleep quality in the general population. The disclosed ECM also provides new measurements of physiologic stress during and following exercise.Type: GrantFiled: September 16, 2019Date of Patent: August 30, 2022Assignee: REVEAL BIOSENSORS, INC.Inventor: Guy Meredith Hatch
-
Publication number: 20220160269Abstract: Physiologic sensors and methods of application are described. These sensors function by detecting recently discovered variations in the spectral optical density at two or more wavelengths of light diffused through the skin. These variations in spectral optical density have been found to consistently and uniquely relate to changes in the availability of oxygen in the skin tissue, relative to the skin tissue's current need for oxygen, which we have termed Physiology Index (PI). Current use of blood gas analysis and pulse oximetry provides physiologic insight only to blood oxygen content and cannot detect the status of energy conversion metabolism at the tissue level. By contrast, the PI signal uniquely portrays when the skin tissue is receiving ‘less than enough oxygen,’ ‘just the right amount of oxygen,’ or ‘more than enough oxygen’ to enable aerobic energy conversion metabolism.Type: ApplicationFiled: February 11, 2022Publication date: May 26, 2022Applicant: REVEAL BIOSENSORS, INC.Inventor: Guy Meredith HATCH
-
Patent number: 11278221Abstract: Physiologic sensors and methods of application are described. These sensors function by detecting recently discovered variations in the spectral optical density at two or more wavelengths of light diffused through the skin. These variations in spectral optical density have been found to consistently and uniquely relate to changes in the availability of oxygen in the skin tissue, relative to the skin tissue's current need for oxygen, which we have termed Physiology Index (PI). Current use of blood gas analysis and pulse oximetry provides physiologic insight only to blood oxygen content and cannot detect the status of energy conversion metabolism at the tissue level. By contrast, the PI signal uniquely portrays when the skin tissue is receiving ‘less than enough oxygen,’ just the right amount of oxygen,? or ‘more than enough oxygen’ to enable aerobic energy conversion metabolism.Type: GrantFiled: March 23, 2020Date of Patent: March 22, 2022Assignee: REVEAL BIOSENSORS, INC.Inventor: Guy Meredith Hatch
-
Patent number: 11207689Abstract: There is provided a cartridge for nucleic acid extraction comprising: a first body having a plurality of chambers in which ports are formed at the bottom; a second body coupled to a lower region of the first body; and a piston disposed rotatably in the centers of the first body and the second body and having a port formed at the bottom thereof; and characterized in that the cartridge comprises a plurality of flow paths formed on the upper region of the second body, one end overlapping the port of the piston and the other end overlapping the port of the first body.Type: GrantFiled: December 27, 2018Date of Patent: December 28, 2021Assignee: SD BIOSENSOR, INC.Inventors: Young Shik Cho, Hyo Guen Lee, Hae Joon Park, Sun Young Lee, Kwan Hun Lim, In Ae Kim, Jae Young Kim, Hyo Lim Park, Dong Hun Kim
-
Publication number: 20210052183Abstract: Systems, methods and computer-readable media are disclosed for providing therapeutic auditory stimulation. Consistent with disclosed embodiments, a system for providing therapeutic auditory stimulation may comprise a diagnostic unit that computes an EEG spectral density of a patient and a heart rate spectral density of a patient and provides values for one or more EEG frequency bands and one or more heart rate frequency bands. The system may also comprise a therapy unit that generates, based on the provided values, one or more stimulation waveforms corresponding to one or more of the EEG frequency bands and provides the stimulation waveforms for therapeutic auditory stimulation. The stimulation waveforms may comprise audible carrier frequencies modulated by signals with frequencies that vary exponentially with time. The EEG frequency bands may comprise the delta, theta, alpha, beta 1, beta 2, and gamma EEG frequency hands.Type: ApplicationFiled: August 11, 2020Publication date: February 25, 2021Applicant: Biosensor, Inc.Inventor: Natalia IZVARINA
-
Patent number: 10772529Abstract: Systems, methods and computer-readable media are disclosed for providing therapeutic auditory stimulation. Consistent with disclosed embodiments, a system for providing therapeutic auditory stimulation may comprise a diagnostic unit that computes an EEG spectral density of a patient and a heart rate spectral density of a patient and provides values for one or more EEG frequency bands and one or more heart rate frequency bands. The system may also comprise a therapy unit that generates, based on the provided values, one or more stimulation waveforms corresponding to one or more of the EEG frequency bands and provides the stimulation waveforms for therapeutic auditory stimulation. The stimulation waveforms may comprise audible carrier frequencies modulated by signals with frequencies that vary exponentially with time. The EEG frequency bands may comprise the delta, theta, alpha, beta 1, beta 2, and gamma EEG frequency hands.Type: GrantFiled: February 11, 2016Date of Patent: September 15, 2020Assignee: BioSensor, Inc.Inventor: Natalia Izvarina
-
Publication number: 20200237274Abstract: Physiologic sensors and methods of application are described. These sensors function by detecting recently discovered variations in the spectral optical density at two or more wavelengths of light diffused through the skin. These variations in spectral optical density have been found to consistently and uniquely relate to changes in the availability of oxygen in the skin tissue, relative to the skin tissue's current need for oxygen, which we have termed Physiology Index (PI). Current use of blood gas analysis and pulse oximetry provides physiologic insight only to blood oxygen content and cannot detect the status of energy conversion metabolism at the tissue level. By contrast, the PI signal uniquely portrays when the skin tissue is receiving ‘less than enough oxygen,’ just the right amount of oxygen,? or ‘more than enough oxygen’ to enable aerobic energy conversion metabolism.Type: ApplicationFiled: March 23, 2020Publication date: July 30, 2020Applicant: REVEAL BIOSENSORS, INC.Inventor: Guy Meredith HATCH
-
Patent number: 10638960Abstract: Physiologic sensors and methods of application are described. These sensors function by detecting recently discovered variations in the spectral optical density at two or more wavelengths of light diffused through the skin. These variations in spectral optical density have been found to consistently and uniquely relate to changes in the availability of oxygen in the skin tissue, relative to the skin tissue's current need for oxygen, which we have termed Physiology Index (PI). Current use of blood gas analysis and pulse oximetry provides physiologic insight only to blood oxygen content and cannot detect the status of energy conversion metabolism at the tissue level. By contrast, the PI signal uniquely portrays when the skin tissue is receiving ‘less than enough oxygen,’ ‘just the right amount of oxygen,’ or ‘more than enough oxygen’ to enable aerobic energy conversion metabolism.Type: GrantFiled: October 24, 2016Date of Patent: May 5, 2020Assignee: REVEAL BIOSENSORS, INC.Inventor: Guy Meredith Hatch
-
Patent number: 10619198Abstract: The present invention relates to a primer for PCR obtained by, directly or through inosine as a linker, linking a complementary nucleotide sequence or a complementary nucleotide sequence including a mis-matched nucleotide sequence to the 5?-terminal of a forward or reverse primer; and to a PCR method including a step of mixing a nucleic acid template in a PCR composition including the primer and then performing PCR on the mixture. The primer for PCR of the present invention includes a complementary nucleotide sequence or a mis-matched nucleotide sequence in a complementary nucleotide sequence, which is linked to the 5?-terminal thereof directly or via a linker, thereby lowering the sensitivity increase due to the increase in amplification products and reducing non-specifically occurring reactions in PCR.Type: GrantFiled: January 7, 2016Date of Patent: April 14, 2020Assignee: SD BIOSENSOR, Inc.Inventors: Yoo-Deok Won, Hae-joon Park, Sunyoung Lee
-
Publication number: 20200085321Abstract: Persons with sleep disordered breathing (SDB) may, or may not, recognize that they have symptoms of SDB, and/or that they may be at-risk of, or suffering certain health problems associated with SDB, including death. The disclosed Energy Conversion Monitor (ECM) sensor, when embodied, for example, in a wearable upper-armband format, has been demonstrated to be more sensitive and responsive than pulse oximetry monitoring of blood oxygen saturation as an indication of hypoxic stress induced by SDB, and is compatible with: (1) inclusion in sleep laboratory polysomnograph (PSG) testing instrumentation, (2) home-based diagnostic testing for SDB, (3) control of home-use airway therapy devices, (4) continuous remote surveillance and refinement of airway therapy, and (5) spot-check and continuous surveillance of sleep quality in the general population. The disclosed ECM also provides new measurements of physiologic stress during and following exercise.Type: ApplicationFiled: September 16, 2019Publication date: March 19, 2020Applicant: REVEAL BIOSENSORS, INC.Inventor: Guy Meredith Hatch
-
Patent number: 10386428Abstract: A system and method are provided to detect target analytes based on magnetic resonance measurements. Magnetic structures produce distinct magnetic field regions having a size comparable to the analyte. When the analyte is bound in those regions, magnetic resonance signals from the sample are changed, leading to detection of the analyte.Type: GrantFiled: June 11, 2015Date of Patent: August 20, 2019Assignee: MENON BIOSENSORS, INC.Inventors: Suresh M. Menon, David E. Newman, Steven C. Chan