Patents Assigned to BIOSIG TECHNOLOGIES, INC.
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Publication number: 20210143851Abstract: Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.Type: ApplicationFiled: November 6, 2020Publication date: May 13, 2021Applicant: BIOSIG Technologies, Inc.Inventors: Budimir S. DRAKULIC, Sina FAKHAR, Thomas G. FOXALL, Branislav VLAJINIC
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Patent number: 10986033Abstract: Systems, apparatus, and methods are disclosed for processing biomedical signals. An electrophysiology (EP) system includes a differential circuit to process the biomedical signals; a differential amplifier circuit to amplify an output of the differential circuit; an analog-to-digital converter to digitize an output of the differential amplifier circuit; a communication module to interface between the analog-to-digital converter and a digital processing stage having a plurality of signal modules; and at least one processor to execute the plurality of signal modules, applying digital signal processing to the output from the analog-to-digital converter, to extract features of interest of the biomedical signals.Type: GrantFiled: October 23, 2019Date of Patent: April 20, 2021Assignee: BioSig Technologies, Inc.Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Publication number: 20210112014Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.Type: ApplicationFiled: December 22, 2020Publication date: April 15, 2021Applicant: BioSig Technologies, Inc.Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Patent number: 10924424Abstract: Systems, methods, and computer program product embodiments are disclosed for processing and displaying multiple signals in near real-time. An embodiment operates by processing, using a first digital signal processor (DSP) of a first signal module, a first packet associated with a first signal. The embodiment also processes, using a second DSP of a second signal module, a second packet associated with a second signal. The embodiment equalizes a first processing delay associated with the first DSP with a second processing delay associated with the second DSP such that the first DSP completes processing of the first packet approximately simultaneously with the second DSP completing processing of the second packet. The embodiment then displays the processed first packet approximately simultaneously with the display of the processed second packet.Type: GrantFiled: June 20, 2019Date of Patent: February 16, 2021Assignee: BioSig Technologies, Inc.Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Publication number: 20210044533Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.Type: ApplicationFiled: October 28, 2020Publication date: February 11, 2021Applicants: BioSig Technologies, Inc., Mayo Foundation for Medical Education and ResearchInventors: Budimir S. DRAKULIC, Sina FAKHAR, Thomas G. FOXALL, Branislav VLAJINIC, Samuel J. ASIRVATHAM
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Patent number: 10911365Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.Type: GrantFiled: May 4, 2020Date of Patent: February 2, 2021Assignee: BioSig Technologies, Inc.Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Publication number: 20210029053Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.Type: ApplicationFiled: October 8, 2020Publication date: January 28, 2021Applicant: BioSig Technologies, Inc.Inventors: Budimir S. DRAKULIC, Sina FAKHAR, Thomas G. FOXALL, Branislav VLAJINIC
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Patent number: 10841232Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.Type: GrantFiled: December 18, 2019Date of Patent: November 17, 2020Assignee: BioSig Technologies, Inc.Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Publication number: 20200267089Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.Type: ApplicationFiled: May 4, 2020Publication date: August 20, 2020Applicant: BioSig Technologies, Inc.Inventors: Budimir S. DRAKULIC, Sina FAKHAR, Thomas G. FOXALL, Branislav VLAJINIC
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Patent number: 10708191Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The embodiment further includes a communications interface communicatively coupled to a remote device, and a processor, coupled to the ECG circuit board, the plurality of IC circuit boards, and the communications interface. The processor is configured to receive, via the communications interface, feedback from the remote device. The processor is further configured to control, via the communication interface, the remote device based on the ECG signal, the IC signals, or the feedback from the remote device.Type: GrantFiled: September 26, 2019Date of Patent: July 7, 2020Assignees: BioSig Technologies, Inc., Mayo Foundation for Medical Education and ResearchInventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic, Samuel J. Asirvatham
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Patent number: 10686715Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.Type: GrantFiled: November 19, 2018Date of Patent: June 16, 2020Assignee: BioSig Technologies, Inc.Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Patent number: 10645017Abstract: Systems, apparatus, and methods are disclosed for conveying signals between a patient and monitoring and treatment devices. An EP system provides large-signal input protection and RF ablation signal noise suppression while preserving the integrity of relevant components of small signals. The EP system has a low-noise amplifier topology with minimal hardware filtering. An input protection circuit shunts to ground signals with amplitude above an ablation voltage. An RF filter circuit linearly attenuates the signals between 300 kHz and 600 kHz. A low-frequency feedback circuit drives a common mode node of the RF filter circuit for additional attenuation. A signal amplification circuit amplifies the signals between 0.01 Hz and 1000 Hz. A fast recovery circuit feeds back a low-frequency voltage signal to the signal amplification circuit to gradually reduce offset voltage of the signals. A high-resolution A/D converter converts the signals from the signal amplification circuit to clean digital signals.Type: GrantFiled: November 19, 2018Date of Patent: May 5, 2020Assignee: BioSig Technologies, Inc.Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Publication number: 20200054287Abstract: Systems, apparatus, and methods are disclosed for processing biomedical signals. An electrophysiology (EP) system includes a differential circuit to process the biomedical signals; a differential amplifier circuit to amplify an output of the differential circuit; an analog-to-digital converter to digitize an output of the differential amplifier circuit; a communication module to interface between the analog-to-digital converter and a digital processing stage having a plurality of signal modules; and at least one processor to execute the plurality of signal modules, applying digital signal processing to the output from the analog-to-digital converter, to extract features of interest of the biomedical signals.Type: ApplicationFiled: October 23, 2019Publication date: February 20, 2020Applicant: BioSig Technologies, Inc.Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Publication number: 20200022591Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The embodiment further includes a communications interface communicatively coupled to a remote device, and a processor, coupled to the ECG circuit board, the plurality of IC circuit boards, and the communications interface. The processor is configured to receive, via the communications interface, feedback from the remote device. The processor is further configured to control, via the communication interface, the remote device based on the ECG signal, the IC signals, or the feedback from the remote device.Type: ApplicationFiled: September 26, 2019Publication date: January 23, 2020Applicants: BioSig Technologies, Inc., Mayo Foundation for Medical Education and ResearchInventors: Budimir S. DRAKULIC, Sina Fakhar, Thomas G. Foxall, Branislav VLAJINIC, Samuel J. ASIRVATHAM
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Publication number: 20200015687Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.Type: ApplicationFiled: September 25, 2019Publication date: January 16, 2020Applicants: BioSig Technologies, Inc., Mayo Foundation for Medical Education and ResearchInventors: Budimir S. DRAKULIC, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic, Samuel J. Asirvatham
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Publication number: 20190365250Abstract: Systems, methods, and computer program product embodiments are disclosed for displaying cardiac signals based on a signal pattern. An embodiment operates by accessing an input cardiac signal. The embodiment matches a portion of the input cardiac signal to a known signal pattern. The embodiment then displays an indication of a degree of the match.Type: ApplicationFiled: August 16, 2019Publication date: December 5, 2019Applicants: BioSig Technologies, Inc., Mayo Foundation for Medical Education and ResearchInventors: Budimir S. DRAKULIC, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic, Samuel J. Asirvatham
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Patent number: 10485485Abstract: Systems, apparatus, and methods are disclosed for bi-directionally conveying biomedical signals between a patient and signal acquisition and processing devices.Type: GrantFiled: February 8, 2019Date of Patent: November 26, 2019Assignee: BioSig Technologies, Inc.Inventors: Budimir S. Drakulic, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Publication number: 20190349310Abstract: Systems, methods, and computer program product embodiments are disclosed for processing and displaying multiple signals in near real-time. An embodiment operates by processing, using a first digital signal processor (DSP) of a first signal module, a first packet associated with a first signal. The embodiment also processes, using a second DSP of a second signal module, a second packet associated with a second signal. The embodiment equalizes a first processing delay associated with the first DSP with a second processing delay associated with the second DSP such that the first DSP completes processing of the first packet approximately simultaneously with the second DSP completing processing of the second packet. The embodiment then displays the processed first packet approximately simultaneously with the display of the processed second packet.Type: ApplicationFiled: June 20, 2019Publication date: November 14, 2019Applicant: BioSig Technologies, Inc.Inventors: Budimir S. DRAKULIC, Sina Fakhar, Thomas G. Foxall, Branislav Vlajinic
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Publication number: 20190343463Abstract: Systems, apparatus, and methods are disclosed for bi-directionally conveying biomedical signals between a patient and signal acquisition and processing devices.Type: ApplicationFiled: February 8, 2019Publication date: November 14, 2019Applicant: BioSig Technologies, Inc.Inventors: Budimir S. DRAKULIC, Sina FAKHAR, Thomas G. FOXALL, Branislav VLAJINIC
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Publication number: 20190348975Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.Type: ApplicationFiled: November 19, 2018Publication date: November 14, 2019Applicant: BioSig Technologies, Inc.Inventors: Budimir S. DRAKULIC, Sina FAKHAR, Thomas G. FOXALL, Branislav VLAJINIC