Abstract: The invention relates to an implantation device (10a-d) comprising at least one medical implant (12a-d) and at least one implantation aid (14a-d) comprising at least one expansion element (16a-d). It is provided that the expansion element (16a-d) can be inserted into at least one cavity (18a-d) of the implant (12a-d), and the at least one cavity (18a-d) can be expanded using the expansion element (16a-d), and, in the end state, the expansion element (16a-d) is disposed at least partially in the at least one cavity (18a-d), wherein the expansion element (16a-d) is designed as a solid body (20a-d).

Abstract: The present invention relates to a biocorrodable implant in which corrosion may be triggered or accelerated after implantation by applying an external stimulus, the implant having a base body which is completely or partially composed of a biocorrodable metallic material, and the base body having a coating with a protective layer which is not biocorrodable. According to the invention, the implant has control elements which are configured in such a way that the protective layer, optionally in combination with the control elements, completely or partially encloses the base body so as to be impermeable to bodily medium, and the protective layer being convertible to a form which is permeable to bodily medium as the result of a change in shape of the control elements which may be regulated and/or controlled by an external stimulus.

Abstract: An embodiment of the present invention relates to a catheter comprising a dilatable balloon, characterized in that the primary balloon wall is produced from a material that comprises or consists of a polyamide/polyvinylpyrrolidone (PA/PVP) polymer mixture.

Abstract: A drug-eluting stent, comprising a base body that is made of an implant material, the base body being partially or entirely covered on the abluminal side with an active ingredient-releasing coating that comprises or is made of a polymer and an active ingredient having an antiproliferative effect, characterized in that the stent's luminal surface and the abluminal surface carrying the active ingredient-releasing coating are covered by a biocorrodible protective layer in a form-fitting manner.

Abstract: A marker composite for medical implants composed of a biocorrodible metallic material and a medical implant comprising an X-ray marker which was made of the marker composite. The marker composite contains a large number of particles composed of a radio-opaque metal, which are embedded in an electrically non-conductive polymer. The particles have an additional electrically non-conductive coating.

Abstract: A medical device including an evaluation unit and an electrode line. The electrode line includes at least one temperature sensor. The temperature sensor delivers a temperature signal to the evaluation unit. The evaluation unit evaluates periodic fluctuations of a signal level of the temperature signal and generates an evaluation output signal qualifying constant wall touching of the electrode line according to whether periodic fluctuations of a signal level of the temperature signal lie below or above a predetermined limit value.

Abstract: An implant having a preferably hollow cylindrical main structure comprising a large number of continuous openings and a coating which releases at least one pharmaceutically active substance. To attain a better distribution of the pharmaceutically active substance, at least 20% of the cross-sectional area, preferably at least 50% of the cross-sectional area, of at least a portion of the openings in a predetermined section of the main structure is covered with the coating which releases at least one pharmaceutically active substance. Furthermore, a system composed of a catheter and such an implant, a simple method for manufacturing such an implant or such a system is provided.

Abstract: At least some embodiments of the invention relates to an implant having a coating that contains or is composed of a functionalized RGD peptidomimetic RGD-P1 having the formula (1) and/or a functionalized RGD peptidomimetic RGD-P2 having the formula (2), and an associated manufacturing method.

Abstract: A release device (100, 100a) for releasing a medical implant (105) from an insertion device (110), with which the implant (105) can be released by a relative movement between a first and a second insertion element (92, 94), the release device having a body (10, 10a) with a proximal end (12)and a distal end (14), wherein a hand grip unit (16) with a first grip segment (18) fixed relative to the body (10, 10a) and at least one movably arranged second grip segment (20, 20a) is provided between the proximal and the distal end (12, 14), wherein the movably arranged second grip segment (20, 20a) is rotatable in the to circumferential direction (22) in order to effect an intended relative movement between the first and the second insertion element (92, 94) of the insertion device (110).

Abstract: A release mechanism (100, 100a) for releasing a medical implant (105) from an insertion device (110), comprising a body (10) having a proximal end (12) and a distal end (14), wherein between the proximal end and the distal end (12, 14) an actuator (16, 16a) is provided, wherein for generating a selective relative displacement between the first and second insertion elements (72; 74) of the insertion device (110), the actuator (16, 16a) has a first and at least a second direction of motion (18; 20), wherein in the first direction of motion (18), the first and second insertion elements (72; 74) can be displaced relative to one another in the longitudinal direction (18), and wherein in the at least second direction of motion (20), the actuator (16, 16a) effects a movement transversely to the longitudinal direction (18).

Abstract: A release device (100) and an insertion device (110) having such a release device (100) for detaching a medical implant from an insertion device (110), in which the implant can be released by way of a relative movement between a first and a second insertion element (52, 54), including a body (10) having a proximal end (12), which faces a user in the usage state, and a distal end (14), which is furthest away from a user in the usage state, wherein a spindle (10a) including at least two speed regions is provided between the proximal end and distal end (14), wherein the spindle (10a) is provided so as to generate a deliberate to relative movement between the first and second insertion elements (52, 54) of the insertion device (110).

Abstract: An insertion device for inserting a medical hybrid implant, wherein the hybrid implant has at least two sub-implants, of which at least one first sub-implant is externally expandable and at least one second sub-implant is self-expanding, including a first insertion element, which has at least one expansion aid for expanding the at least first externally expandable sub-implant, and a second insertion element and at least one third insertion element for releasing the at least second self-expanding sub-implant, wherein the at least first externally expandable sub-implant is expandable by means of the expansion aid and the at least second self-expanding sub-implant can be released by a relative movement between the second insertion element and the at least third insertion element, wherein the first insertion element is arranged displacably inside the at least second insertion element.

Abstract: One embodiment of the invention relates to a coated implant having a base body composed of a biocorrodible magnesium alloy. The coating of the implant comprises: (i) a base layer, which is applied to the base body, composed of a basic polymer having a repeater unit that contains units of formula (1) or (2) and (ii) a polymeric cover layer that is applied directly to the base layer.

Abstract: An implant and method for producing an implant, in particular an intraluminal endoprosthesis, with a body, wherein the body contains iron or an iron alloy, comprising the following steps: a) providing the implant body (1), b) applying a metallic coating comprising as main constituent at least one element of the group containing tantalum, niobium, zirconium, aluminum, magnesium, vanadium, molybdenum, hafnium, and wolfram onto at least a portion of the body surface, and c) plasmachemical treatment of the portion of the body surface provided with the coating in an aqueous solution for producing a plasmachemically generated layer (3, 5, 7) by means of applying a plasma-generating pulsating voltage to the body of the implant, wherein the pulsating voltage has sufficient energy that the metallic coating (3, 5, 7) is temporarily and sectionally ionized up to the underlying implant body (1) in such a manner that the generated layer has pores (5) which extend at least partially up to the implant body.

Abstract: Implantable object, comprising a layer, comprising a copolymer that contains an aptamer, wherein bonds in the copolymer can be broken in accordance with a binding event at the aptamer, such that the copolymer degrades.

Abstract: An insertion element (100), which is designed to cooperate with an insertion device (200) for inserting a medical implant (222) into a human or animal body. The insertion element (100) comprises a sleeve (10) with a distal end (40) and a proximal end (30) opposite the distal end (40), said sleeve also having at least one expandable region (10a), which can be transferred from a first state of small clear cross section at least at the proximal end (30) into a second state of larger clear cross section at least at the proximal end (30), wherein the expandable region (10a) of the sleeve (10) is flatter in the first state than in the second state.

Abstract: A release device (160, 160a, 160b) for releasing a medical implant (155) from an insertion device (120), said release device comprising a body (10, 10a, 10b) with a proximal end (12) and a distal end (14), wherein a first grip segment (34, 34?), a second grip segment (34, 34?) and at least one actuator (26) are provided between the proximal and the distal end (12, 14), wherein the at least one actuator (26) is manually operable and can be brought substantially into at least the first grip segment (34) substantially axially displaceably in order to effect an intended relative movement in the longitudinal direction (22) between the first and the second insertion element (140, 145) of the insertion device (120).

Abstract: A release device (150, 150a, 150b) for detaching a medical implant (105) from an insertion device (110), comprising a body (10, 10a, 10b) having a proximal end (12), which during use lies furthest from a distal end (120) of the insertion device (110), and a distal end (14), which during use faces the distal end (120) of the insertion device (110), wherein at least one first actuator (16, 18) is provided between the proximal and distal ends (12, 14), wherein the at least first actuator (16, 18) can be tilted about an axis substantially perpendicularly to at least one of the insertion elements (132, 134) so as to effect a targeted relative movement in the longitudinal direction between the first and second insertion elements (132, 134) of the insertion device (110).

Abstract: An implant comprising a main body made of magnesium or a biocorrodible magnesium alloy and a corrosion-inhibiting passivation layer covering the main body. The passivation layer is characterized in that it contains a 3-polyhydroxyalkanoate and the 3-polyhydroxyalkanoate is a homomer or copolymer with a polymer segment of formula (1): where R=propyl, butyl, pentyl or hexyl.

Abstract: A cover device (100), an insertion device (120), and a method for covering an at least partly released medical implant (102), which can be released from an insertion device (120) by a relative movement between a first and a second insertion element (52; 54), the cover device comprising at least one expansion body (10), at which a first radial extension (16) and at least one second radial extension (18) can be set, wherein the second radial extension (18) of the at least one expansion body (10) can be adapted to at least one radial extension (108) of the at least partly released medical implant (102) when the at least partly released medical implant (102) is covered, wherein the at least one expansion body (10) can be expanded substantially homogeneously in the circumferential direction (22) at least in at least one axial portion (20).