Abstract: A method for producing a semifinished part (20) for an implant, in particular for an intraluminal endoprosthesis, which comprises the following steps: a) providing a first sleeve (11) from a first metallic material and at least one second sleeve (12, 13) from a second metallic material, b) arranging the first sleeve (11) and the at least one second sleeve (12, 13) into one another in such a manner that the sleeve combination (10) forms at least a press fit between said sleeves, and c) forming the sleeve combination (10) at an increased temperature by means of extrusion. The invention further includes a method for producing an implant, to a corresponding semifinished part or a corresponding implant, respectively.

Abstract: A method for manufacturing an implant and an implant, in particular an intraluminal endoprosthesis, including a body having a coating on at least a portion of the surface thereof, and the degradation of which can be influenced from the outside in a targeted manner, the method having the following steps: a) providing an implant body, and b) applying a coating to the surface of the implant body, wherein the coating comprises unfilled cavities, preferably in the form of microbubbles (2).

Abstract: One embodiment of the invention relates to a catheter shaft comprising (i) a first tube made of an extrudable copolymer that has reactive groups, and (ii) a second tube made of a polymeric material, which can be welded to the first tube, wherein the polymeric material of the second tube can be welded to the first tube at a temperature ?200° C.

Abstract: A method for producing an implant and the implant itself, particularly an intraluminal endoprosthesis, wherein the implant is produced from a preferably hollow cylindrical semifinished article (10), wherein the semifinished article contains magnesium or a magnesium alloy, the method comprising preparing the semifinished article (10), and shaping the semifinished article at a temperature of between 250° C. and 550° C. using a tool, which has a metallic lubricant containing gallium and/or a gallium compound on at least a part of its surface that will come into contact with the semifinished article.

Abstract: A crimping device for mounting a vascular stent, or a heart valve prosthesis introduced in a vascular stent, on an insertion catheter, comprising a forming tool having a rotationally symmetrical forming cavity, which at one end comprises a stent receiving section, at the opposing end a stent outfeed section and in between these a tapering section, and a pushing tool, which comprises a retaining and handling section and a stent forming section, wherein the latter is designed to penetrate the forming cavity of the forming tool from the open end of the stent receiving section and to seize and push back the vascular stent introduced there through the tapering section.

Abstract: An embodiment of the invention relates to a release device for releasing a medical implant from an insertion device, in the case of which the implant can be released by way of a relative motion between a first and a second insertion element, comprising a clamping element for clamping the implant in the insertion device, having a proximal end which is distant from a distal end of the insertion device in the state of use, and a distal end which faces the distal end of the insertion device in the state of use, wherein the clamping unit comprises a first component and at least one second component, which clamp the implant there between in the clamped state. The invention further relates to an insertion device comprising such a release device and a method for clamping an implant in an insertion device.

Abstract: A combined rolling membrane-balloon catheter, in particular for expanding stenoses in bodily vessels, including: an outer shaft (1) and an inner shaft (4) which is axially displaceable therein, an intermediate shaft (7) situated between the inner and outer shafts (4, 1) which is likewise axially displaceable, a rolling membrane (12) which is attached in a pressure-tight manner between the distal end (2) of the outer shaft (1) and the distal end (11) of the inner shaft (4), and which may be displaced between a passive position within the outer shaft (1) and an active position which is distally expanded from the outer shaft (1) by the action of pressure, and a dilatable balloon (14) which is attached in a pressure-tight manner between the distal end (11) of the inner shaft (4) and the distal end of the intermediate shaft (7), and which may be displaced between a passive position within the outer shaft (1) and proximally in front of the rolling membrane (12), and an active position which is distally expanded fro

Abstract: An embodiment of the present invention relates to a balloon catheter, which has a drug-releasing coating and/or cavity filling on at least parts of the outwardly facing surface of the dilatable balloon, characterized in that the coating comprises a drug and a gelatin mixture, the gelatin components of the gelatin mixture comprising 10-90 wt. % high-bloom gelatin having a gel strength of ?250 bloom and 90-10 wt. % medium-bloom gelatin having a gel strength of ?50 to <250 bloom, the specifications in wt. % relating to the total weight of the gelatin components of the gelatin mixture.

Abstract: The invention relates to a heart valve prosthesis comprising biological material or plastic material, having a suture or knot which comprises an X-ray visible material and the position of which identifies the valve plane.

Abstract: The invention is directed to a device (100) comprising a medical implant (30), in particular a stent, for implantation in an animal body and/or human body, wherein the medical implant (30) is disposed on a distal end (16) of a carrier (10) for positioning at the intended site, and the medical implant (30) is enclosed at least temporarily by an outer sleeve (20). The outer sleeve (20) on the distal end (18) of the carrier (10) is detachably attachable or attached to the carrier (10).

Abstract: A releasing device (100) for detaching a medical implant (105) from an insertion device (110), wherein the implant (105) can be released by a relative movement between a first and a second insertion element (52, 54), the releasing device comprising a clamping body (10) for clamping the implant (105) in the insertion device (110), with a proximal end (12) which, in the state of use, is remote from a distal end (120) of the insertion device (110) and a distal end (14) which, in the state of use, faces toward the distal end (120) of the insertion device (110), wherein in the clamping state, the clamping body (10) encloses the implant (105) at least at one place (106) in a cap-like manner.

Abstract: A release mechanism (100, 100a) for releasing a medical implant (105) from an insertion device (110), comprising a body (10) having a proximal end (12)and a distal end (14), wherein between the proximal end and the distal end (12, 14) an actuator (16, 16a) is provided, wherein for generating a selective relative displacement between the first and second insertion elements (72; 74) of the insertion device (110), the actuator (16, 16a) has a first and at least a second direction of motion (18; 20), wherein in the first direction of motion (18), the first and second insertion elements (72; 74) can be displaced relative to one another in the longitudinal direction (18), and wherein in the at least second direction of motion (20), the actuator (16, 16a) effects a movement transversely to the longitudinal direction (18).

Abstract: A release device (100, 100a) or an insertion device (110) including the release device for releasing a medical implant (105) from an insertion device (110), in the case of which the implant (105) can be released by way of a relative motion between a first and a second insertion element (52, 54), comprising a body (10) having a proximal end (12) which faces a user during use, and a distal end (14) which is remote from the user during use, wherein an actuator (16) is provided between the proximal and the distal end (12, 14), wherein the actuator (16) can be driven hydraulically to generate a targeted relative motion between the first and the second insertion element (52, 54) of the insertion device (110).

Abstract: A release device (100) and an insertion device (110) having such a release device (100) for detaching a medical implant from an insertion device (110), in which the implant can be released by way of a relative movement between a first and a second insertion element (52, 54), including a body (10) having a proximal end (12), which faces a user in the usage state, and a distal end (14), which is furthest away from a user in the usage state, wherein a spindle (10a) including at least two speed regions is provided between the proximal end and distal end (14), wherein the spindle (10a) is provided so as to generate a deliberate to relative movement between the first and second insertion elements (52, 54) of the insertion device (110).

Abstract: Various embodiments of the invention relate to a cRGD peptide derivative and an associated manufacturing method, and to an implant having a coating containing a cRGD peptide derivative. One aspect of the invention is the provision of a cRGD peptide derivative having the formula (1): wherein x=0-8, in particular 4-8, and R is a hydrophobic group.

Abstract: An implant, having a preferably hollow-cylindrical base body and comprising a device that is used to measure the degree of endothelialization and disposed on and/or in the base body, wherein the device comprises an acoustic resonator and/or an electric resonator. The invention further relates to a system, comprising a catheter and such an implant.

Abstract: A balloon catheter, including an outer shaft with a distal end and a fluid line, an inner part located distal anterior to its distal end, as well as a balloon that can be inflated under the influence of a fluid that has been pressurized by the fluid line, that is fastened fluid-tight onto the distal end section of the outer shaft with a first fastening zone at its proximal end, and fluid-tight onto inner part with a second fastening zone at its distal end, whereby the balloon, on at least one of its two ends is designed without cone and with essentially unvarying thin wall thickness, the balloon is provided on at least one of its two ends with respectively one twist anterior to its fastening zone, and a second balloon is placed above the first balloon and is also provided with a twist on at least one of its two ends anterior to the fastening zone, that is directed in the opposite direction of the twist of the first balloon end that is positioned underneath.

Abstract: An implant comprising a perforated, preferably hollow-cylindrical basic structure which has at least one section, wherein in each section at least one strut is arranged. In order to achieve a more homogenous coverage of the wall of the treated vessel, a good interlock with the wall of the treated body cavity and a better distribution of the mechanical stresses and elongations, the strut has a multiplicity of identical, simple and interconnected elements, the basic shape of which is substantially similar to the shape of base line elements of an imaginary first order base line which likewise runs in the section, wherein the imaginary first order base line represents a reference line for the arrangement of the elements and the elements are not more than half the size of the base line elements.

Abstract: A release device for disengaging a medical implant from an insertion device, in which the implant is releasable by a relative movement between a first insertion element and a second insertion element, comprising a body having a proximal end, which faces toward a user in the usage state, and a distal end, which is remote from the user in the usage state, a toothed rack having a first speed range and a second speed range being provided between the proximal end and the distal end, the toothed rack being provided to generate a targeted relative movement between the first insertion element and the second insertion element of the insertion device. Furthermore, the invention relates to an insertion device having such a release device.