Abstract: System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.
Type:
Application
Filed:
December 5, 2018
Publication date:
June 6, 2019
Applicant:
Blood Cell Storage, Inc.
Inventors:
Michael W. Reed, Steven J. Geelhood, Paul C. Harris, Lynn M. Barker, Perry Hargrave, Oliver Z. Nanassy
Abstract: System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.
Type:
Grant
Filed:
December 21, 2015
Date of Patent:
December 18, 2018
Assignee:
Blood Cell Storage, Inc.
Inventors:
Michael W. Reed, Steven J. Geelhood, Paul C. Harris, Lynn M. Barker, Perry Hargrave, Oliver Z. Nanassy
Abstract: System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.
Type:
Application
Filed:
December 21, 2015
Publication date:
July 21, 2016
Applicant:
Blood Cell Storage, Inc.
Inventors:
Michael W. Reed, Steven J. Geelhood, Paul C. Harris, Lynn M. Barker, Perry Hargrave, Oliver Z. Nanassy
Abstract: System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.
Type:
Grant
Filed:
July 23, 2013
Date of Patent:
December 22, 2015
Assignee:
Blood Cell Storage, Inc.
Inventors:
Michael W. Reed, Steven J. Geelhood, Paul C. Harris, Lynn M. Barker, Perry Hargrave, Oliver Z. Nanassy
Abstract: Alkyl amine dyes, oligonucleotide probes prepared from the alkyl amine dyes, phosphoramidites and solid supports prepared from the alkyl amine dyes, and methods of labeling biological agents using the alkyl amine dyes.
Abstract: System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.
Type:
Application
Filed:
July 23, 2013
Publication date:
July 3, 2014
Applicant:
Blood Cell Storage, Inc.
Inventors:
Michael W. Reed, Steven J. Geelhood, Paul C. Harris, Lynn M. Barker, Perry Hargrave, Oliver Z. Nanassy
Abstract: A system, method, and kit for extracting nucleic acid from a sample containing nucleic acid uses an extraction device with an elongate channel. Fluids are provided to the channel via gravity feed to the inlet port. The flow rate and other flow behavior may be controlled with a siphon provided at the outlet port.
Abstract: System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.
Type:
Grant
Filed:
April 23, 2007
Date of Patent:
July 30, 2013
Assignee:
Blood Cell Storage, Inc.
Inventors:
Michael W. Reed, Steven J. Geelhood, Paul C. Harris, Lynn M. Barker, Perry Hargrave, Oliver Nanassy
Abstract: Low pKa fluorescent compounds, compositions that include the compounds, bioconjugates made from the compounds, and methods for making and using the compounds and bioconjugates.
Abstract: Processes are disclosed for storing nucleic acid in a stable form. A solution comprising nucleic acid is applied to an unmodified, silica-based substrate whereby at least a portion of the nucleic acid binds to a surface of the substrate, the bound nucleic acid is washed and dried, and the resulting dried nucleic acid on the substrate is stored at from 5° C. to 60° C. for a period of at least one week.
Abstract: Alkyl amine dyes, oligonucleotide probes prepared from the alkyl amine dyes, phosphoramidites and solid supports prepared from the alkyl amine dyes, and methods of labeling biological agents using the alkyl amine dyes.
Abstract: A system, method, and kit for extracting nucleic acid from a sample containing nucleic acid uses an extraction device with an elongate channel. Fluids are provided to the channel via gravity feed to the inlet port. The flow rate and other flow behavior may be controlled with a siphon provided at the outlet port.
Abstract: Devices, processes, and kits for the extraction of nucleic acids from biological samples are disclosed. The devices comprise a first port, a second port, and a binding chamber intermediate and in fluid communication with the first port and the second port. The binding chamber comprises an unmodified flat glass surface effective for binding a heterogeneous population of nucleic acids. The first port, second port, and binding chamber define a continuous fluid pathway that is essentially free of nucleic acid-specific binding sites.
Type:
Application
Filed:
April 20, 2012
Publication date:
September 20, 2012
Applicant:
BLOOD CELL STORAGE, INC.
Inventors:
Michael W. Reed, Oliver Z. Nanassy, Paul V. Haydock, Nigel Rudra Sharma, Ronald L. Bardell, Perry Hargrave
Abstract: Methods and apparatus for testing the sterility of a product to be administered to a patient. The sterility of the product is tested by monitoring the pH change of a culture medium in contact with any culturable organisms (e.g., bacteria) that are collected by filtration of the product to be tested.
Type:
Grant
Filed:
June 8, 2009
Date of Patent:
May 22, 2012
Assignee:
Blood Cell Storage, Inc.
Inventors:
Michael W. Reed, Lynn M. Barker, Evert Jan Klip
Abstract: Devices, processes, and kits for the extraction of nucleic acids from biological samples are disclosed. The devices comprise a first port, a second port, and a binding chamber intermediate and in fluid communication with the first port and the second port. The binding chamber comprises an unmodified flat glass surface effective for binding a heterogeneous population of nucleic acids. The first port, second port, and binding chamber define a continuous fluid pathway that is essentially free of nucleic acid-specific binding sites.
Type:
Grant
Filed:
January 2, 2009
Date of Patent:
April 24, 2012
Assignee:
Blood Cell Storage, Inc.
Inventors:
Michael W. Reed, Oliver Z. Nanassy, Paul V. Haydock, Nigel Rudra Sharma, Ronald L. Bardell, Perry Hargrave