Abstract: Device and methods for extracting and analyzing nucleic acids from biological samples.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Abstract: Processes for extracting nucleic acid from a biological sample and related assemblies and kits are disclosed. The processes comprise the steps of (a) providing a device comprising an inner surface, an outer surface, a first port, and a second port, wherein the inner surface is composed of unmodified, smooth glass and defines a tubular lumen providing fluid communication between the first port and second port, wherein the lumen is circular, oval, or elliptical in cross-section, and wherein the lumen is essentially free of nucleic acid-specific binding sites; (b) introducing a nucleic acid-containing sample into the lumen of the device via the first port; (c) allowing nucleic acid in the sample to bind to the unmodified smooth glass surface; and (d) washing the bound nucleic acid.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Abstract: Device and methods for extracting and analyzing nucleic acids from biological samples.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Abstract: Methods and apparatus for testing the sterility of a product to be administered to a patient. The sterility of the product is tested by monitoring the pH change of a culture medium in contact with any culturable organisms (e.g., bacteria) that are collected by filtration of the product to be tested.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Abstract: Device and methods for extracting and analyzing nucleic acids from biological samples.

Abstract: Devices, processes, and kits for the extraction of nucleic acids from biological samples are disclosed. The devices comprise a first port, a second port, and a binding chamber intermediate and in fluid communication with the first port and the second port. The binding chamber comprises an unmodified flat glass surface effective for binding a heterogeneous population of nucleic acids. The first port, second port, and binding chamber define a continuous fluid pathway that is essentially free of nucleic acid-specific binding sites.

Abstract: An apparatus to lyophilize, store, transport, rehydrate, and process aqueous biological materials in a container which maintains sterility of its contents, allows container shrinkage after lyophilization, and optimally permits filtration or dialysis of the contents in situ, without the need for a second or series of additional containers. These benefits are met by a microporous container constructed of a membrane that is water vapor permeable, yet water impermeable.

Abstract: Device and methods for extracting and analyzing nucleic acids from biological samples.

Abstract: System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.