Abstract: The present invention describes novel tumor-specific phosphorylated peptides, nucleic acids encoding those peptides, and antibodies generated against said peptides. The genes, peptides, and antibodies described herein may be used as diagnostic indicators of the presence of breast cancer and/or used in therapeutics to treat breast cancer.

Abstract: An endoscope biopsy device has a hub, an insertion tube connected to the hub, an endoscope module connected to the hub, and a biopsy module connected to the hub. The endoscope module includes a fiber optic line extending through the hub and into the insertion tube. The biopsy module is configured to admit biopsy tools to the patient through the insertion tube from the biopsy module while simultaneously providing a visual examination of the portion of the patient from which the biopsy is taken. In some embodiments, the endoscope biopsy device is configured to perform a biopsy during a ductoscopy on a human patient.

Abstract: A toe dynamometer is configured to accurately and precisely measure toe extensor strength. The toe dynamometer includes a platform configured to accommodate a patient's foot, and a sensor assembly comprising a force sensor and a toe cap connected to the force sensor. The force sensor is configured to measure forces applied to the force sensor by toe flexion on the force sensor and from toe extension away on the force sensor through the toe cap.

Abstract: A sorbent-based oil skimmer is configured to collect oil from an oil layer and passively deposit the oil in an encasing, where the oil can be continuously or periodically removed. The oil skimmer includes an encasing and a sponge that is partially enclosed within the encasing. The sponge has a top sheet in contact with the oil layer and a shell connected to the top sheet, where the shell extends into the encasing. Oil collected by the top sheet is conveyed through the shell, where it is deposited into the encasing under the force of gravity. In some applications, the sponge is manufactured from a silicone-based polymer that has been impregnated with carbonaceous material. The skimmer may optionally include counterweights, ballast tanks, buoyancy adjustment systems and propulsion modules.

Abstract: A set of target peptides are presented by HLA A*0201 on the surface of ovarian cancer cells. They are envisioned to among other things (a) stimulate an immune response to the proliferative disease, e.g., ovarian cancer, (b) function as immunotherapeutics in adoptive T-cell therapy or as a vaccine, (c) facilitate antibody recognition of tumor boundaries in surgical pathology samples, (d) act as biomarkers for early detection and/or diagnosis of the disease, and (e) act as targets in the generation antibody-like molecules which recognize the target-peptide/MHC complex.

Abstract: Pharmaceutical particles having an inner portion comprising an agonist of peroxisome proliferator-activated receptor ? (PPAR?) and a biodegradable polymer; and an outer coating comprising an emulsifier which surrounds the inner portion, wherein the agonist may be a fibrate, and the particle contains at least about 5 wt % to about 25 wt % of the agonist, and wherein the particle has a sustained delayed release of the agonist in a range of at least about 1 to 12 months when in an aqueous solution or physiological environment. The pharmaceutical particles may be used, for example, to treat diseases and conditions such as ocular disorders which benefit from PPAR? agonism.

Abstract: Methods and systems for alleviating disorders and complications associated with autonomic nervous system dysfunction. The approach generally includes measuring heart rate signals from a subject to measure heart rate variability and determine a heart rate variability threshold, determining that the subject is experiencing autonomic nervous system dysfunction, and alerting the subject to stimulate the auricular branch of the vagus nerve with an ear device.

Abstract: Compositions containing a phenylquinoline derivative compound having peroxisome proliferator-activated receptor a (PPAR?) agonistic activity, and methods of their use in enhancing PPAR? activity in retinal cells, and in treating ocular disorders or conditions, such as but not limited to retinal inflammation, retinal neovascularization, retinal vascular leakage, retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, and diabetic macular edema are disclosed.

Abstract: A spray-capillary device is configured to process ultra low-volume samples. The spray-capillary device includes a spray capillary that includes an inlet end and a discharge end. The spray capillary includes a porous section at the discharge end. A downstream connector provides an interface between the porous section of the spray capillary, a conductive fluid, and a high voltage electrical source. The application of voltage to the downstream connector causes electrospray ionization, which can be used to draw ultra law volume samples into the inlet end. A gas injection assembly can be used to increase the pressure on the inlet end of the spray capillary to encourage movement of the sample through the spray capillary. The spray-capillary device is well suited for providing ultra low samples to a mass spectrometer detection device.

Abstract: Methods, systems and non-transitory computer readable mediums for processing radar signals to recover signals inside a blind region are disclosed. A transmission signal is transmitted from a radar system. The radar system receives a return signal. The return signal includes a first portion of the transmission signal leaked during transmission and a second portion reflected from an object within the blind region. The return signal is partially decoded by zeroing out the first portion of the transmission signal to form a modified return signal. Pulse compression is performed over the modified return signal to form a compressed return signal. The compressed return signal is processed to calculate moment products. The moment products are calibrated with a calibration factor, wherein the calibration factor is multiplied against only calculated moment products of range gates which have been partially decoded.

Abstract: Provided are methods useful for preventing and mitigating radiation injury, including acute radiation syndrome, comprising administering to a subject a therapeutically effective amount of a compound represented by formula I: or a pharmaceutically acceptable salt thereof, wherein Z is —O— or —N(H)—.

Abstract: A melt blowing apparatus and method includes a melt blowing die and at least one louver. The melt blowing die has a nosepiece comprising at least one aperture and at least one air slot adjacent the aperture. The at least one louver is movably positioned adjacent a face of the melt blowing die forming a zone through which can pass air and molten filaments from the air slots and nosepiece of the melt blowing die.

Abstract: Immunogenic peptides, fusion polypeptides, and carrier molecules which include the immunogenic peptides, and immunogenic compositions which include these immunogenic peptides, fusion polypeptides, and/or carrier molecules bearing the peptides, and which are able to elicit antibody production against Haemophilus influenzae (Hi), are disclosed. Also disclosed are methods of their use in causing an antibody response against one or more strains of Hi.

Abstract: Compositions of nanoparticle-based stimulation fluids and methods of use for acid diversion from high permeability zones into low permeability zones to achieve deep penetration of wormholes in subterranean formations, such as carbonate formations. Certain embodiments include a gel precursor composition comprising metal oxide nanoparticles, such as silicon dioxide nanoparticles as a gelling agent, and magnesium chloride.

Abstract: A frame is configured to improve the seal of a face mask worn on the face of a human. The frame generally includes one or more flexible pieces that conform to the human wearer's face. The frame compresses the face mask against the face of the human wearer. In some embodiments, the frame includes a nose section that conforms to the human's nose, a pair of cheek sections each extending laterally away from the nose section and across the human's cheek bones and downward toward the human's mandible, a plurality of strap anchors on the cheek sections, and one or more straps connected to the strap anchors on the cheek sections. The frame may also include a chin section that is unitary with the cheek sections, or a separate chin strap that is connected to the cheek sections with elastomeric bands.

Abstract: A semiconductor PV detector comprises a Ge layer and a Pb-chalcogenide layer coupled to the Ge layer. The Ge layer comprises a first conduction band with a first conduction potential and a first valence band with a first valence potential. The Pb-chalcogenide layer comprises a second conduction band with a second conduction potential that is lower than the first conduction potential and a second valence band with a second valence potential that is lower than the first valence potential. The Ge layer and the Pb-chalcogenide layer form a heterojunction configured to allow electrons to flow from the Ge layer to the Pb-chalcogenide layer and allow holes to flow from the Pb-chalcogenide layer to the Ge layer.

Abstract: A bacteriophage structure, a method of making the structure, and uses of the structure are described. The structure is a substrate with a surface having an ordered arrangement of parallel microridges thereon. Each microridge is composed of a plurality of nanoridges and has a longitudinal axis. Each nanoridge contains a bundle of phage nano fibers having longitudinal axes. The phage nanofibers in each nanoridge bundle are arranged in a substantially smectic alignment. The longitudinal axis of each microridge is perpendicular to the longitudinal axes of the phage nanofibers which make up the nanoridges of the microridge. The structure may be used as a growth surface for inducing differentiation of stem cells such as neural progenitor cells.

Abstract: A method comprises obtaining temporal measurements associated with a heterogeneous material; building a numerical model of a material by assigning initial approximations to the temporal measurements; modifying the numerical model to create a modified numerical model; generating simulated temporal measurements associated with the temporal measurements using the modified numerical model; determining a reward, a penalty, or a modification based on a quality of a fit between the temporal measurements and the simulated temporal measurements; and updating the numerical model based on the reward, the penalty, or the modification.

Abstract: Mounting systems for solar panel assemblies and related methods are generally describes. In some embodiments, a clamp adapter may be used to mount a conventional panel support structure of a solar panel assembly to a conventional bracket of a base assembly without the use of bolts in at least some embodiments. The clamp adapter may include a rail slot for receiving the structure, a lower flange for receiving a lower surface of a mounting lip of the bracket, and a lateral flange for receiving an upper surface of the mounting lip. The lower flange may be angled to accommodate a variety of mounting lip angles. In some embodiments, the mounting system may also include a connector configured to mechanically connect the bracket and structure.

Abstract: Novel compositions and methods for the treatment and prevention of malaria are disclosed herein.