Patents Assigned to Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
  • Patent number: 10907351
    Abstract: A hybrid core comprising a matrix and tubular structural reinforcements, such as a ductile matrix core reinforced with ductile hollow tubes, as well as panels which comprise such hybrid core. Embodiments of the invention manifest resistance to both interfacial debonding and ballistic penetration.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: February 2, 2021
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
    Inventors: Guoqiang Li, Gefu Ji
  • Patent number: 10900303
    Abstract: Aspects of magnetic gradient drilling are described. In one embodiment, a system includes a drill pipe, drilling fluid, and a magnetic assembly tool connected to or integrated with the drill pipe. Among other elements, the magnetic assembly tool can include a magnetic field generator configured to generate a magnetic field and create an additional pressure drop in the drilling fluid outside the drill pipe, and a magnetic shielding material configured to shield the magnetic field from inside the drill pipe.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: January 26, 2021
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
    Inventors: Babak Akbari, Garrett L. Nielsen
  • Patent number: 10897921
    Abstract: A method is disclosed for making palatable methionine-restricted foods, to deliver a methionine-restricted diet to human or veterinary patients. A protein or a food product containing protein is partially oxidized, preferably with ozone, to oxidize nearly all of the methionine and cysteine. After oxidation, tryptophan and lysine are optionally added back since they tend to be oxidized also. Optionally, a small amount of methionine is also added back so that the final methionine is within a preferred range of about 0.85 to about 1.8 gram methionine per 100 gram total protein, preferably about 1.2 gram per 100 gram total protein.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: January 26, 2021
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: John W. Finley, Thomas Gettys, Frank L. Greenway
  • Publication number: 20210011017
    Abstract: Methods, compositions, devices, and kits are described herein that are useful for detecting BoHV-1 infection in animals and/or for distinguishing animals that may benefit from administration of BoHV-1 tmv vaccine.
    Type: Application
    Filed: June 9, 2020
    Publication date: January 14, 2021
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Shafiqul Islam Chowdhury
  • Patent number: 10876030
    Abstract: Embodiments of the present disclosure provide for modified cement material, methods of reducing or stopping cement shrinkage, methods of making modified cement material, and the like.
    Type: Grant
    Filed: April 20, 2017
    Date of Patent: December 29, 2020
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
    Inventors: Arash Dahi Taleghani, Guoqiang Li
  • Patent number: 10870881
    Abstract: The present invention relates to a device comprising a biomolecular processor. Each biomolecular processor has one or more bioreactor chambers defined by a solid substrate; a support structure within each bioreactor; a cleaving enzyme immobilized to the support structure and operatively positioned within the bioreactor chamber to cleave monomer or multimer units of a biopolymer molecule operatively engaged by the cleaving enzyme; and one or more time-of-flight channels formed in the solid substrate and fluidically coupled to said one or more bioreactor chambers. Each of the time-of-flight channels have two or more sensors including at least (i) a first sensor contacting the time-of-flight channel proximate to the input end of the channel and (ii) a second sensor contacting the time-of-flight channel proximate to the output end of channel. The present invention further relates to methods of sequencing and identifying biopolymer molecules using the device.
    Type: Grant
    Filed: February 19, 2018
    Date of Patent: December 22, 2020
    Assignees: CORNELL UNIVERSITY, UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, NORTHEASTERN UNIVERSITY, BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
    Inventors: Steven A. Soper, Francis Barany, George Grills, Robin McCarley, Collin J. McKinney, Dorel Moldovan, Michael C. Murphy, Dimitris Nikitopoulos, Sunggook Park, Elizabeth J. Podlaha-Murphy
  • Patent number: 10872708
    Abstract: A phase contrast X-ray imaging system includes: an illumination source adapted to illuminate a region of interest; a diffraction grating adapted to receive illumination from the illuminated region of interest, the diffraction grating comprising a spatial structure having a first periodicity superimposed with a second periodicity that is different from the first periodicity; and a detector adapted to detect illumination passing through the diffraction grating, wherein the spatial structure is defined by varying height and/or pitch, and wherein the spatial structure imparts a first phase dependence based on the first periodicity and an additional phase dependence based on the second periodicity on the illumination passing through the diffraction grating.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: December 22, 2020
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Joyoni Dey, Narayan Bhusal, Leslie Butler, Jonathan P. Dowling, Kyungmin Ham, Varshni Singh
  • Patent number: 10865147
    Abstract: High-strength concrete-like FG blends and methods for producing them are described. The blend includes FG, hydraulic cement, additional alkali material, and pozzolanic material. The blend further includes an admixture used in the formulation of concrete. The blend further includes an aggregate. The aggregate is a coarse aggregate or a fine aggregate.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: December 15, 2020
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Michele Barbato, Yasser Bigdeli, Maria Teresa Gutierrez-Wing, Charles Davis Lofton
  • Patent number: 10866186
    Abstract: Embodiments of the present application are directed toward a focusing Schlieren technique that is capable of adding color-coded directional information to the visualization of density gradients. Other advantages of the technique can include that it does not require manual calibration, has a simple design and is sensitive enough to be used in compact experimental setups. Certain embodiments include the use of a color-coded source image that replaces the conventional source grid. The technique may benefit from a computer-controlled digital background, which is used for both illumination and display of color-coded source images.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: December 15, 2020
    Assignee: Board of Supervisors Louisiana State University and Agricultural and Mechanical College
    Inventor: Ingmar Schoegl
  • Patent number: 10842382
    Abstract: A contact-type endoscope surface enhanced Raman scattering (SERS) probe includes a gradient-index (GRIN) lens, a transparent substrate adhered to the GRIN lens, and a rough metallic layer adhered to an opposite side of the transparent substrate from the GRIN lens. The GRIN lens focuses light from a Raman spectrometer onto the rough metallic layer, and the rough metallic layer is positioned at the distal end of the contact-type endoscope SERS probe.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: November 24, 2020
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Martin Feldman, Dooyoung Hah
  • Patent number: 10834885
    Abstract: A hybrid rice designated ‘LAH169’ is disclosed.
    Type: Grant
    Filed: June 26, 2019
    Date of Patent: November 17, 2020
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: James H. Oard, Steven D. Linscombe
  • Patent number: 10830757
    Abstract: The present invention is directed to methods comprising a device that comprises a biomolecular processor and one or more nanotubes. Each biomolecular processor comprises a bioreactor chamber defined by a solid substrate, a plurality of spaced support structures within said bioreactor chamber and attached to the solid substrate, one or more nanotubes defined by the solid substrate and fluidically coupled to the bioreactor chamber and one or more capture molecules immobilized to some or all of said plurality of spaced support structures, said one or more capture molecules suitable to bind to a portion of a target nucleic acid molecule in a sample. The nanotubes have a passage extending between an input end proximate to the bioreactor chamber and an output end distal to the bioreactor chamber, and comprises one or more nanopores within the passage with each nanopore having a reduced diameter relative to the passage.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: November 10, 2020
    Assignees: The University of North Carolina at Chapel Hill, Cornell University, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Steven A. Soper, Francis Barany, Sunggook Park, Michael Murphy, Collin J. McKinney, John William Efcavitch, Mateusz Hupert
  • Patent number: 10829804
    Abstract: The present invention is directed methods for identifying, in a sample, one or more target nucleotide sequences differing from other nucleotide sequences in the sample by one or more nucleotides, one or more copy numbers, one or more transcript sequences, and/or one or more methylated residues, using ligation detection reactions, polymerase mediated extension reactions, and/or cleavage reactions. The present invention is also directed to methods for identifying, in a sample, one or more nucleotides in a target nucleotide sequence.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: November 10, 2020
    Assignees: The University of North Carolina at Chapel Hill, Cornell University, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Francis Barany, John William Efcavitch, Steven A. Soper, Sunggook Park
  • Publication number: 20200345836
    Abstract: The present invention provides vaccines for treating or preventing a herpes simplex virus infection and methods of using and making the vaccine. Further provided are recombinant herpes simplex virus genomes, recombinant viruses, and immunogenic compositions.
    Type: Application
    Filed: February 7, 2020
    Publication date: November 5, 2020
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Konstantin G. Kousoulas
  • Patent number: 10822752
    Abstract: An artificial turf system has polymeric turf fibers resembling grass, and infill particles interspersed among said turf fibers. At least some of the infill comprises synthetic composite particles containing a thermoplastic polymer and cellulosic fibers, in which thermoplastic polymer is a matrix that binds together the other components of each synthetic particle into a composite particle.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: November 3, 2020
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Qinglin Wu
  • Publication number: 20200330405
    Abstract: This invention features compositions, methods, and kits for treating conditions associated with pathological ocular neovascularization, reducing scarring in the eye, treating dry eye, treating macular degeneration, and treating keratitis by administering a serotonin receptor agonist.
    Type: Application
    Filed: May 1, 2018
    Publication date: October 22, 2020
    Applicant: The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College
    Inventors: Timothy Paul Foster, Charles David Nichols
  • Publication number: 20200330522
    Abstract: A method of preventing or reducing the occurrence and/or development of a hernia within a subject at risk of developing a hernia includes implanting a graft material in contact with an opening in an abdominal wall. The graft material promotes healing of the abdominal wall and includes placental or placental derived tissue.
    Type: Application
    Filed: March 27, 2020
    Publication date: October 22, 2020
    Applicant: The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Frank Ho Pak Lau, Ian Hodgdon, Michael Cook
  • Patent number: 10786503
    Abstract: The present disclosure provides compositions comprising a lyn kinase activator and TRPM8 agonist, and to methods of: reducing blood glucose levels, weight gain, or fat depot levels; treating metabolic syndrome, Syndrome X, obesity, prediabetes, type II diabetes, type I diabetes; treating hypercholesterolemia, hypertension, coronary heart disease, diabetic neuropathy, lipodystrophy, diabetic retinopathy, erectile dysfunction, kidney disease, dyslipidemia, dyslipoproteinemia, a peroxisome proliferator activated receptor-associated disorder, septicemia, a thrombotic disorder, or pancreatitis; inducing the beiging of adipocytes; and preventing pancreatic beta cell degeneration.
    Type: Grant
    Filed: April 9, 2018
    Date of Patent: September 29, 2020
    Assignees: Melior Pharmaceuticals I, Inc., Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Andrew G. Reaume, Weina Cong, Frank Greenway, Ann Coulter
  • Publication number: 20200255631
    Abstract: The poor water solubility of high molecular weight chitosan has limited its use in areas such as food and beverage products, post-harvest treatments, cosmetic and pharmaceutical products, medical treatments, and environmental pollution treatments. Disclosed is a high-molecular-weight, solid-state chitosan powder that is completely water-soluble.
    Type: Application
    Filed: November 14, 2016
    Publication date: August 13, 2020
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Witoon Prinyawiwatkul, Zhimin Xu, Yixiao Shen
  • Publication number: 20200247716
    Abstract: A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and a means for molecular scale healing is disclosed; the composition has the ability to resolve structural defects by a bio-mimetic close-then heal process. In use, the shape memory polymer serves to bring surfaces of a structural defect into approximation, whereafter use of the means for molecular scale healing allowed for movement of the healing means into the defect and thus obtain molecular scale healing. The means for molecular scale healing can be a thermoplastic such as fibers, particles or spheres which are used by heating to a level at or above the thermoplastic's melting point, then cooling of the composition below the melting temperature of the thermoplastic. Compositions of the invention have the ability to not only close macroscopic defects, but also to do so repeatedly even if another wound/damage occurs in a previously healed/repaired area.
    Type: Application
    Filed: April 17, 2020
    Publication date: August 6, 2020
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Guoqiang Li, Harper Meng