Abstract: Vectors and methods are provided for introducing genetic material into cells of a chicken or other avian species. More particularly, vectors and methods are provided for transferring a transgene to an embryonic chicken cell, so as to create a transgenic hen wherein the transgene is expressed in the hen's oviduct and the transgene product is secreted in the hen's eggs and/or those of her offspring. In a preferred embodiment, the transgene product is secreted in the egg white.
Type:
Application
Filed:
September 8, 2004
Publication date:
March 24, 2005
Applicant:
Board of Trustees Operating Michigan State University
Abstract: An improved method is provided for performing nanomanipulations using an atomic force microscope. The method includes: performing a nanomanipulation operation on a sample surface using an atomic force microscope; determining force data for forces that are being applied to the tip of the cantilever during the nanomanipulation operation, where the force data is derived along at least two perpendicularly arranged axis; and updating a model which represents the topography of the sample surface using the force data.
Type:
Grant
Filed:
May 2, 2003
Date of Patent:
March 8, 2005
Assignee:
Board of Trustees operating Michigan State University
Inventors:
Ning Xi, Wai Keung Fung, Mengmeng Yu, Guangyong Li
Abstract: The present invention provides a multiplex RT-PCR/PCR method, which enables in a single assay the simultaneous detection of any combination of bovine rotavirus, bovine coronavirus, Cryptosporidium parvum, and optionally, Escherichia coli strains producing K99 pili or heat-stable enterotoxin STa.
Type:
Application
Filed:
February 20, 2001
Publication date:
February 3, 2005
Applicant:
Board of Trustees operating Michigan State University
Abstract: A design template includes a torso section being one of a group of a 95th percentile male, 50th percentile male and 5th percentile female having each being one of a group of an ERECT posture, a NEUTRAL posture and a SLUMPED posture.
Type:
Grant
Filed:
October 10, 1997
Date of Patent:
January 11, 2005
Assignee:
The Board of Trustees Operating Michigan State University
Inventors:
Herbert M. Reynolds, Robert Kerr, Raymond Brodeur, Khaldoun Rayes, Douglas Neal, Yuntao Cui
Abstract: Vectors and methods are provided for introducing genetic material into cells of a chicken or other avian species. More particularly, vectors and methods are provided for transferring a transgene to an embryonic chicken cell, so as to create a transgenic hen wherein the transgene is expressed in the hen's oviduct and the transgene product is secreted in the hen's eggs and/or those of her offspring. In a preferred embodiment, the transgene product is secreted in the egg white.
Type:
Grant
Filed:
April 18, 1997
Date of Patent:
November 30, 2004
Assignee:
Board of Trustees Operating Michigan State University
Abstract: A process for the preparation of mesostructured organofunctional silica and silica-alumina compositions is described. The process uses a water soluble silicate to form the compositions, which have hexagonal, wormhole or foam mesostructures. The compositions are useful for catalytic and sorption applications.
Type:
Application
Filed:
November 20, 2003
Publication date:
November 18, 2004
Applicant:
Board of Trustees operating Michigan State University
Inventors:
Thomas J. Pinnavaia, Jainisha R. Shah, Seong-Su Kim
Abstract: The complete sequence of the canine von Willebrand Factor cDNA and deduced amino acid sequence is provided. The mutation which causes von Willebrand's Disease in Scottish Terriers, Doberman pinschers, Shetland sheepdogs, Manchester terriers and Poodles are also provided. Methods for detecting carriers of the defective vWF gene are also provided.
Type:
Grant
Filed:
September 15, 2000
Date of Patent:
August 24, 2004
Assignee:
Board of Trustees Operating Michigan State University
Inventors:
Patrick J. Venta, George J. Brewer, Vilma Yuzbasiyan-Gurkan, William D. Schall
Abstract: A teleportal system which provides remote communication between at least two users. A projective display and video capture system provides video images to the users. The video system obtains and transmits 3D images which are stereoscopic to remote users. The projective display unit provides an augmented reality environment to each user and allows users to view, unobstructed, the other local users, and view a local site in which they are located. A screen transmits to the user the images generated by the projective display via a retro-reflective fabric upon which images are projected and reflected back to the user's eyes.
Type:
Grant
Filed:
December 22, 2000
Date of Patent:
August 10, 2004
Assignees:
Board of Trustees operating Michigan State University, University of Central Florida
Abstract: The present invention relates to genes encoding proteins involved in prokaryotic type or plastid division and/or morphology and the encoded proteins, and in particular to isolated Ftn2 (ARC6), ARC5, and Fzo-like genes and polypeptides. The present invention also provides methods for using Ftn2 (ARC6), ARC5, and Fzo-like genes, and polypeptides.
Type:
Application
Filed:
June 20, 2003
Publication date:
July 15, 2004
Applicant:
The Board of Trustees Operating Michigan State University
Inventors:
Katherine W. Osteryoung, Stanislav Vitha, Olga A. Koksharova, Hongbo Gao
Abstract: A bioengineered synthesis scheme for the production of 1,2,3,4-tetrahydroxybenzene from a carbon source is provided. Methods of producing 1,2,3,4-tetrahydroxybenzene from a carbon source based on the synthesis scheme are also provided. Methods are also provided for converting 1,2,3,4-tetrahydroxybenzene to 1,2,3-trihydroxybenzene by catalytic hydrogenation.
Type:
Grant
Filed:
May 7, 2002
Date of Patent:
June 15, 2004
Assignee:
Board of Trustees operating Michigan State University
Abstract: The present invention provides novel purified and isolated nucleic acid sequences associated with disease resistance and tolerance in plants. Methods of using the nucleic acid sequences to confer disease resistance and tolerance to plants are also provided.
Type:
Grant
Filed:
April 20, 2001
Date of Patent:
November 11, 2003
Assignee:
Board of Trustees operating Michigan State University
Abstract: The cDNA encoding digalactosyldiacylglycerol galactosyltransferase (DGD1) is provided. The deduced amino acid sequence is also provided. Methods of making and using DGD1 to screen for new herbicides and alter a plant's leaf lipid composition are also provided, as well as expression vectors, transgenic plants or other organisms transfected with said vectors.
Type:
Grant
Filed:
May 5, 2000
Date of Patent:
November 4, 2003
Assignee:
Board of Trustees operating Michigan State University
Abstract: A process for the preparation of 1,5-dideoxy-1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to the hexitol. The hexitols are useful as drugs.
Type:
Application
Filed:
May 15, 2003
Publication date:
October 30, 2003
Applicant:
Board of Trustees Operating Michigan State University
Inventors:
Rawle I. Hollingsworth, Gabriela Pistia-Brueggeman
Abstract: A process for the separation of a polyol or multiple polyols in admixture with other organic compounds, usually those produced with the polyol, is described. The process uses a distillation in a column (11) of a cyclic acetal from an aqueous solution which acetal is formed in a reaction mixture of the polyol and an aldehyde or ketone. The polyols, such as ethylene glycol and propylene glycol, are staple articles of commerce with many uses.
Type:
Application
Filed:
January 7, 2003
Publication date:
October 2, 2003
Applicant:
Board of Trustees Operating Michigan State University
Inventors:
Dennis J. Miller, James E. Jackson, Shubham P. Chopade, Atulkumar D. Dhale, Angela M. Clark, Christopher W. Kiesling
Abstract: A bioengineered synthesis scheme for the production of quinic acid from a carbon source is provided. Methods of producing quinic acid from a carbon source based on the synthesis scheme as well as conversion of quinic acid to hydroquinone are also provided.
Type:
Grant
Filed:
March 15, 2002
Date of Patent:
September 16, 2003
Assignee:
Board of Trustees operating Michigan State University
Abstract: The present invention provides a peptide mimotope of the non-peptide mycotoxin deoxynivalenol. In particular, the peptide mimotope competes with deoxynivalenol for binding to a monoclonal antibody and is antagonistic to the inhibitory effects of deoxynivalenol on in vitro protein synthesis. The present invention also provides a method that uses the peptide mimotope to determine whether corn, grains or mixed feed is contaminated with fungi that produces deoxynivalenol. The present invention further provides transgenic plants resistant to deoxynivalenol.
Type:
Application
Filed:
April 9, 2002
Publication date:
September 4, 2003
Applicant:
Board of Trustees operating Michigan State University
Inventors:
Lynn Patrick Hart, James J. Pestka, Qiaoping Yuan
Abstract: A bioengineered synthesis scheme for the production of shikimic acid from a carbon source is provided. Methods of producing shikimic acid from a carbon source based on the synthesis scheme are also provided.
Type:
Grant
Filed:
January 29, 1999
Date of Patent:
September 2, 2003
Assignee:
Board of Trustees operating Michigan State University
Inventors:
John W. Frost, Karen M. Frost, David R. Knop
Abstract: Draper is a new blueberry variety of Vaccinium corymbosum from the Michigan State University breeding program. It is composed primarily of genes of Vaccinium corymbosum, but has a small contribution (<5%) from V. tenellum, V. ashei and V. darrowi. It is a productive, early mid-season ripening variety with very high fresh market quality and probably a long storage life. It is intended for areas where northern highbush cultivars are grown successfully. Plants of Draper are vigorous and upright. Canes are numerous, moderately branched and the fruit are well exposed. Its berries are moderately large, have small, dry picking scars, excellent powder-blue color, delicious flavor and excellent firmness. The size of the fruit is unusually regular and is presented in a loose cluster.
Type:
Grant
Filed:
January 23, 2003
Date of Patent:
August 24, 2004
Assignee:
Board of Trustees operating Michigan State University
Abstract: Liberty is a new blueberry variety of Vaccinium corymbosum. It is a productive, very late ripening variety with high fresh market quality intended for areas where northern highbush varieties are grown successfully. Plants of Liberty are vigorous and upright. Canes are numerous, moderately branched and the fruit are well exposed. Its berries are moderately large, have small, dry picking scars, excellent powder-blue color, delicious flavor and excellent firmness. Liberty has a harvest season that begins about 5 days before the variety known as ‘Elliott’.
Type:
Grant
Filed:
January 23, 2003
Date of Patent:
September 14, 2004
Assignee:
Board of Trustees operating Michigan State University
Abstract: Aurora is a new blueberry variety of Vaccinium corymbosum. It is a productive, very late ripening variety with high fresh market quality intended for areas where northern highbush varieties are grown successfully. Plants of Aurora are vigorous and upright. Canes are numerous, moderately branched and the fruit are well exposed. Its berries are moderately large, have small, dry picking scars, excellent powder-blue color, delicious flavor and excellent firmness. Aurora has a harvest season that begins about 5 days after the variety known as ‘Elliott.
Type:
Grant
Filed:
January 23, 2003
Date of Patent:
September 28, 2004
Assignee:
Board of Trustees operating Michigan State University