Abstract: Mesostructured and microporous to mesoporous organofunctionalized silica compositions are described. The compositions incorporate the organofunctional group L as part of a LSiO3 unit in the framework of the compositions. In addition the compositions incorporate the organofunctional group R as part of a O3Si—R—siO3 unit in the framework of the compositions. The compositions are useful as molecular sieves, supports for catalysts and numerous other applications requiring an organo group on surfaces of a silica.

Abstract: The preferred embodiment of a seismic sensor array includes a sheet of material and seismic sensors mounted to the sheet. In a further aspect of the present invention, the array includes devices to make the seismic sensor array portable and transportable. In another aspect of the present invention, the seismic sensor array is part of a seismic measurement recording system which includes a data collection box and a computer.

Abstract: The present invention provides novel organic copolymers comprising alternating functional groups, wherein one functional group is phosphonate. In one embodiment, the copolymers comprise alternating phosphonate and N-substituted succinimide functional groups. In another embodiment, the copolymers are synthesized from maleimide and vinyl ether monomers, wherein the vinyl ether monomer possesses a pendant phosphonate functionality and the maleimide monomer is an N-substituted maleimide. Methods of synthesizing thin films with the novel organic copolymers, as well as chemical precipitation methods using the novel organic copolymers, are also provided.

Abstract: The present invention provides a method and system for stabilizing a rotor about its geometric center in a magnetic bearing system at a constant rotor speed. In the method, the controller for controlling the magnetic bearing uses an adaptive control algorithm which simultaneously identifies and compensates for synchronous sensor runout and rotor mass unbalance while determining a control action that drives the rotor rotating at a constant speed to its geometric center. The identification of sensor runout and mass unbalance is by varying the magnetic stiffness which is achieved by perturbation of the bias currents in opposing electromagnet coils in a manner that does not alter the equilibrium of the rotor while it is rotating at a constant speed.

Abstract: A human pancreatic ductal epithelial cell line immortalized with the human papilloma virus E6 and E7 genes which has stem cell-like characteristics and which can be induced to differentiate into ductal-like cells and beta-like cells that produce insulin. The immortal cells or derivative thereof are useful for treating insulin-dependent diabetes and in assays for determining the ability of a chemical to induce pancreatic stem cell differentiation or malignancy.

Abstract: Mesoporous hexagonal, cubic or wormhole aluminosilicates derived from zeolite seeds using an ionic structure directing agent are described. The aluminum in the structures is stable so that the framework of the structures does not collapse when heated in the presence of water or water vapor (steam). The steam stable aluminosilicates can be used as acid catalysts for hydrocarbon conversions, including the fluidized bed catalytic cracking and the hydrocracking of petroleum oils, and other cracking of organic compounds.

Abstract: Mesoporous hexagonal, cubic or wormhole aluminosilicates derived from zeolite seeds using an ionic structure directing agent are described. The aluminum in the structures is stable so that the framework of the structures does not collapse when heated in the presence of water or water vapor (steam). The steam stable aluminosilicates can be used as acid catalysts for hydrocarbon conversions, including the fluidized bed catalytic cracking and the hydrocracking of petroleum oils, and other cracking of organic compounds.

Abstract: Mesoporous hexagonal, cubic or wormhole aluminosilicates derived from zeolite seeds using an ionic structure directing agent are described. The aluminum in the structures is stable so that the framework of the structures does not collapse when heated in the presence of water or water vapor (steam). The steam stable aluminosilicates can be used as acid catalysts for hydrocarbon conversions, including the fluidized bed catalytic cracking and the hydrocracking of petroleum oils, and other cracking of organic compounds.

Abstract: Porous inorganic silica foam compositions are derived from water soluble silicate precursors and swollen non-ionic polymer templates are described. The compositions are useful as catalyst supports and as catalysts in hydrocarbon cracking and organic reactions, among other applications.

Abstract: Nanomechanisms are employed in nanomemory elements which, in turn, are employable in nanoscale memory devices. A nanoscale particle is enclosed within a nonocapsule to create a bistable device which is both readable and writable in a variety of ways. A nonamechanism for use in a nanoscale memory element includes a first element in the form of a nanoassembly having a cavity and second element in the form of a nanostructure which is removeably disposed within the cavity. In one embodiment, the nanoassembly is demonstrated as a C480 capsule and the nanostructure is demonstrated as a charged hd 60 fullerene molecule. The nanoscale memory devices combine high switching speed, high packing density and stability with non0volatility of the stored data.

Abstract: A bioengineered synthesis scheme for the production of shikimic acid from a carbon source is provided. Methods of producing shikimic acid from a carbon source based on the synthesis scheme are also provided.

Abstract: A method using irradiation of substrates (12) with ultra violet light to remove a surface contaminant is described. The light can be pulsed or continuous. The treated surfaces are more paintable and bondable.

Abstract: The present invention relates to a modified enzyme of a non-heme iron (II) dependent family of oxygenases and oxidases which renders the enzyme dependent on bicarbonate for activity. In a preferred embodiment, the modification is an arginine, lysine, or other amino acid that is two amino acid residues upstream of a histidine residue that is an iron ligand in the enzyme and is one of the histidine residues of the 2-histidine-1-aspartic acid trifacial motif. In particular, the modified enzymes are isopenicillin N synthetase, deacetoxycephalosporin C synthetase, and deacetoxycephalosporin C synthetase/deacetylcephalosporin C synthetase which are used to make antibiotics. The present invention further provides a method for making antibiotics using a modified enzyme such as isopenicillin N synthetase, deacetoxycephalosporin C synthetase, and deacetoxycephalosporin C synthetase/deacetylcephalosporin C synthetase wherein the modification renders the enzyme dependent on bicarbonate for activity.

Abstract: A method and apparatus is provided for detection of volatile products from a sample using a transducer which changes voltage as a function of contact of the volatile products with the transducer to produce a gas signature of the volatile products and a spectrophotometer to analyze the volatile products to produce a spectral footprint of the volatile products. The apparatus and method are used to detect spoilage of a biological material, such as a food. The apparatus is also used to detect microorganisms and by comparing the gas signature and spectral footprint to a library of gas signatures and spectral footprints, the apparatus enables identification of the microorganisms and in particular identification of pathogenic microorganisms.

Abstract: The present invention provides a human gene sequence that encodes the CDDP-1 polypeptide, which is involved in cell differentiation, in particular differentiation of undifferentiated progenitor cells into neutrophils, monocytes/macrophages, mast cells, and/or erythroid cells. Assays for detecting CDDP-1 expression, vectors that express CDDP-1, methods for using CDDP-1 to induce or promote cell differentiation, and transgenic animals deficient in one or both CDDP-1 alleles are described.

Abstract: The present invention provides a novel bi-directional promoter. The present invention further provides methods of producing proteins of interest and methods of controlling gene expression using the bi-directional promoter. The present invention also provides methods of expressing one or more proteins of interest from a novel bi-directional promoter of the present invention. The present invention thus provides improved methods of regulating gene expression in plants or other organisms and expressing one or more proteins concurrently in a variety of cell types.

Abstract: The complete sequence of the canine von Willebrand Factor cDNA and deduced amino acid sequence is provided. The mutation which causes von Willebrand's Disease in Scottish Terriers, a single base deletion in exon 4, has also been determined. Methods for detecting carriers of the defective vWF gene are also provided.

Abstract: The present invention relates to a sensor for measuring the instantaneous rate of mass flow and the cumulative mass flow in steady or unsteady flows of single-phase liquids or gases in a duct. By measuring the shear stress or the streamwise pressure gradient at the duct wall, and relating it to mass flow through solutions to the Navier Stokes equations of fluid mechanics, information on mass flow through the entire duct cross sectional area is deduced.

Abstract: A process for the preparation of 1,5-dideoxy-1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to the hexitol. The hexitols are useful as drugs.

Abstract: A neutral templating route to mesoporous molecular sieves based on H-bonding and self-assembly between neutral primary amine or diamine surfactants (S°) and neutral inorganic precursors (I°) has been used to prepare hexagonal and lamellar mesoporous silicas with site isolated transition metal centers. This templating approach allows for the preparation of hexagonal or hexagonal-like mesoporous oxidation catalysts with large framework wall thickness of at least about 17 Å, small elementary particle size (≦400 Å), and unique combinations of framework-confined mesopores and textural mesopores while at the same time providing for facile recovery of the neutral template by simple solvent extraction.