Abstract: A method of assessing soil heave includes providing a plurality of determined values of a shear modulus of soil, the determined values being values of the shear modulus of the soil at different times; and determining a change over time in the shear modulus of the soil, based on the plurality of determined values of the shear modulus of the soil. The soil may have been treated by adding a stabilizer to the soil. The soil may be hydrated. A system for assessing soil heave includes a bender element disposed in soil, for determining a change over time of a shear modulus of the soil, and a time domain reflectometer probe disposed in the soil, for determining a change over time of moisture content of the soil. The determined change over time of the shear modulus and the determined change over time of the moisture content are used to assess heaving of the soil.

Abstract: Certain embodiments are directed to composition and methods related to DCLK1-S specific binding agents.

Abstract: Disclosed are nanostructured gold films which may be produced by solution-phase depositions of gold ions onto a variety of surfaces. The resulting plasmonic gold films are used for enhanced spectroscopic-based immunoassays in multiplexed microarray format with detection mechanisms based on either surface-enhanced Raman scattering or near-infrared fluorescence enhancement. The preparation of the films and subsequent modifications of the gold film surfaces afford increased sensitivity for various microarrays. The films are discontinuous, forming gold “islands.” Sensitivity, size, shape, and density of the nanoscopic gold islands comprising the discontinuous nanostructured gold film are controlled to enhance the intensity of Raman scattering and fluorescence in the near-infrared, allowing for improved measurements in clinical diagnostic or biomedical research applications.

Abstract: Methods and apparatus for converting kinetic energy of an energetic particle into electrical energy and for accelerating charged particles. A stack of substantially parallel conductors separated by gaps is disposed such that the conductors are substantially parallel to the surface of a cathode, with the conductors mutually electrically uncoupled. An anode is disposed at an end of the stack of conductors distal to the cathode, and a power management system applies a bias voltage between the cathode and the anode and collects charge deposited at the anode in the form of current in an external electrical circuit.

Abstract: A probe device for detecting atherosclerotic plaque may include: an elongate shaft having a proximal end for coupling with a catheter and a distal end; an opening in a side of the shaft; a scintillating window disposed over the opening to form a water tight seal and thus form an imaging window compartment; a 45-degree rotating mirror disposed at least partially within the imaging window compartment; and an ultrasound transducer disposed at least partially within the imaging window compartment. The probe is a dual-modality, catheter radionuclide imaging and photoacoustic tomography (CRI-PAT) probe.

Abstract: The present invention includes a treatment system and methods for removing waste or other agents from a fluid stream, the system comprising: an inlet flow path for receiving a fluid stream from a source outside the treatment system; a vessel for containing the fluid stream, the vessel comprising a permeable filter configured for biological and physical treatment of the fluid stream, the filter comprising one or more nano-thin film or polymer composite layers of carbon materials assembled in sp2 hybridized structures comprising carbon-carbon bonds, wherein the waste or agent is removed as it flows through pores in the film composite; and a drain fluidly connected to the vessel for discharging treated fluid stream from the vessel from which the waste or agents have been removed.

Abstract: The subject invention provides an apparatus for cooling and/or freezing samples. In an exemplary embodiment, the apparatus is a stackable chilling plate used in a comet assay. In specific embodiments, the chilling plate can accommodate glass slides deposited with an agarose gel suspension, wherein the gel is cured by a refrigerant disposed underneath a thermally-conductive top plate. Advantageously, the cooling/freezing apparatus provided herein can easily accommodate the placement of multiple cellular sample slides in a compact configuration.

Abstract: A dental implant comprising a base, a central shaft and a shock absorber spacing and allowing limited movement between the base and the central shaft.

Abstract: A photovoltaic device is provided. The photovoltaic device includes a metal salt layer disposed adjacent to a perovskite layer. The metal salt layer diffuses into the perovskite layer. Methods for fabricating the photovoltaic device are also provided.

Abstract: A polymeric dielectric may include a coordination complex of a modified elastic polymer and a metal cation. The modified elastic polymer may include an organic ligand moiety that coordinates the metal cation in a main chain of the elastic polymer. Provided are a method of manufacturing the same, and an electronic device and a thin film transistor including the same.

Abstract: A nanofiber forest on a substrate can be patterned to produce a patterned assembly of nanofibers that can be drawn to form nanofiber sheets, ribbons, or yarns.

Abstract: Embodiments of the invention are directed to methods and compositions using low dose sorafenib to enhance a cancer therapy.

Abstract: Certain embodiments are directed to materials and devices to be used in conjuction with interventional medical procedures. In certain aspects the interventional procedure is ultrasound guided venous cathterization.

Abstract: Systems and methods for stimulating tissue. Exemplary embodiments include systems and methods configured to maintain one electrode at a fixed voltage potential and switching a second electrode between different fixed voltage potentials.

Abstract: Disclosed are an organic semiconductor thin film, a manufacturing method thereof, and a thin film transistor and an electronic device including the organic semiconductor thin film. The organic semiconductor thin film includes a matrix. The matrix includes an elastomer and nanoconfined polymer structures embedded in the matrix. The nanoconfined polymer structures form a polymer network. The nanoconfined polymer structures include a conjugation semiconductor polymer. The conjugation semiconductor polymer includes a repeating unit having at least one conjugation system in its main chain. The nanoconfined polymer structures are present in an upper surface layer and a lower surface layer of the organic semiconductor thin film respectively.

Abstract: Methods of treating a depressive disorder or an anxiety disorder in a subject in need of such treatment are described. A therapeutically effective amount of a composition comprising Ac-Nle4-c[Asp5-His6-(NMe)D-Nal(2?)7-Arg8-Trp9-(NMe)Lys10]-NH2 (PEPTIDE 9), in a pharmaceutically acceptable carrier is administered to the subject. PEPTIDE 9 is a selective MC5R antagonist, in which administration thereof to the subject can treat the depressive or generalized anxiety disorder with clinical improvement observed in a relatively short time.

Abstract: The invention relates to an ophthalmoscope comprising a camera and an associated illumination device; the invention further concerns a novel method for processing a plurality of images of the eye taken by said device; and software, typically included in said ophthalmoscope, for executing said method.

Abstract: Provided is a separatome-based recombinant peptide, polypeptide, and protein expression and purification platform based on the juxtaposition of the binding properties of host cell genomic peptides, polypeptides, and proteins with the characteristics and location of the corresponding genes on the host cell chromosome, such as that of E. coli, yeast, Bacillus subtilis or other prokaryotes, insect cells, mammalian cells, etc. This platform quantitatively describes and identifies priority deletions, modifications, or inhibitions of certain gene products to increase chromatographic separation efficiency, defined as an increase in column capacity, column selectivity, or both, with emphasis on the former. Moreover, the platform provides a computerized knowledge tool that, given separatome data and a target recombinant peptide, polypeptide, or protein, intuitively suggests strategies leading to efficient product purification.

Abstract: Tridentate platinum, palladium, and gold complexes of Formulas A-I and A-II and tridentate iridium and rhodium compounds of Formulas B-I, B-II, and B-III suitable for delayed fluorescent and phosphorescent or phosphorescent emitters in display and lighting applications.

Abstract: (E)-2-(2-Quinolin-2-yl-propenyl)-phenol, 2-Quinolin-2-yl-ylethynyl-phenol and salts thereof are useful as medicaments, especially for treatment of an angiogenesis-related disease or disorder.