Abstract: Apparatus and methods are disclosed for generating and outputting physiological event results from physiological data related to a patient. Physiological event results include results predicting and/or detecting individual physiological events related to a medical condition of the patient.

Abstract: A process for the treatment of biomass to render structural carbohydrates more accessible and/or digestible using concentrated ammonium hydroxide with or without anhydrous ammonia addition, is described. The process preferably uses steam to strip ammonia from the biomass for recycling. The process yields of monosaccharides from the structural carbohydrates are good, particularly as measured by the enzymatic hydrolysis of the structural carbohydrates. The monosaccharides are used as animal feeds and energy sources for ethanol production.

Abstract: A method and system to “pump” radiation therapy (RT) images and associated patient information on an Image Guided Radiation Therapy (IGRT) system to a Record and Verify (R&V) system via a standard DICOM connection to allow remote image viewing. Targeted image files in IGRT systems are searched for and transferred automatically. The user identifies the “inlet,” i.e. the source from which the image files are searched, and the “outlet,” i.e., the DICOM server to which the “pumped” imaged are directed. The images can be sent in their original form or fused. The “input” source is scanned periodically at a user-determined time interval. In order not to send the same image multiple time, a time filter skips images generated before a user-selected time and date.

Abstract: The present invention concerns the methods and compositions involving nucleic acids with long repeat sequences. In some embodiments of the invention, there are methods for generating such a nucleic acid, and in other methods, there are methods for using such a nucleic acid to screen for candidate therapeutic compounds. Furthermore the present invention relates to methods of screening for Notch inhibitors and other substances that may be used to treat muscle loss and wasting.

Abstract: The present invention relates to a composition for the use in improving vascular health, including treating and preventing vascular diseases and diseases related thereto, using a botanical extract of oil palm vegetation liquor from the palm oil milling process.

Abstract: A benign all-wet process for stripping photoresist after an implantation process performed to fabricate a device is provided. A method of stripping implanted resist includes a first step of disrupting a crust formed on the surface of the resist during the implantation process and then removing the underlying resist. In accordance with embodiments of the invention, a catalyzed hydrogen peroxide (CHP) chemical system is used to disrupt the crust and allow for low temperature (<180° C.) removal of the underlying resist.

Abstract: The isolation and characterization of two protein isoforms collected green fluorescent copepods is described herein. The new Pontella mimocerami GFP-like isoforms pmimGFP1 and pmimGFP2 of the present invention are quick to mature and rapidly produce a fluorescent signal. The two isoforms are very similar in molar extinction coefficients (ME) with 105,000 M?1 cm?1 for pmimGFP1 and 103,000 M?1cm?1 for pmimGFP2, respectively. The relative brightness of these two new copepod GFP-like proteins is the highest measured for any isolated GFP-like protein.

Abstract: The present invention includes compositions, methods, systems for the controlled delivery of an active agent in a tablet polymer comprising two or more layers, wherein each of the two or more layers comprises at least one active agent and at least one molecular recognition polymer, wherein the two or more layers are compressed into a single tablet.

Abstract: A method of differentiating among the presence of ductal carcinoma in situ in the breast, benign fibroadenoma of the breast, and non-cancerous breast tissue in a subject is disclosed. The method involves measuring the concentration of at least one protein biomarker selected from a group of forty-nine differentially expressed proteins in the saliva of persons with DCIS, or benign fibroadenoma, or in persons who are cancer-free. The resulting test data is compared to a reference panel. From the comparison the presence in the subject of either ductal carcinoma in situ of the breast, or benign fibroadenoma of the breast is determined.

Abstract: The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (ALDH) enzymatic activity, as well as compositions and formulations comprising the compounds. The present disclosure provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition.

Abstract: According to the present invention, there is provided an improved refreshable tactile display apparatus including a housing, bias compression springs, sliding blocks, pins, and a shape memory alloy wire. The sliding block is actuated by the interaction between the bias compression spring and the shape memory alloy wire. The shape memory alloy wire is then activated by current driven from a power supply in either a modulated or unmodulated fashion.

Abstract: Disclosed are microfluidic devices and systems for the desalination of water. The devices and systems can include an electrode configured to generate an electric field gradient in proximity to an intersection formed by the divergence of two microfluidic channels from an inlet channel. Under an applied bias and in the presence of a pressure driven flow of saltwater, the electric field gradient can preferentially direct ions in saltwater into one of the diverging microfluidic channels, while desalted water flows into second diverging channel. Also provided are methods of using the devices and systems described herein to decrease the salinity of water.

Abstract: Compositions and methods of synthesis of anionic surfactants by alkoxylation of a Guerbet alcohol (GA) having 12 to 36 carbon atoms using butylene oxide, and optionally propylene oxide and/or ethylene oxide followed by the incorporation of a terminal anionic group are described herein. The GA of the present invention is made by a facile and inexpensive method that involves high temperature base catalyzed dimerization of alcohols with 6 to 18 carbon atoms. The large hydrophobe ether surfactants of the present invention find uses in enhanced oil recovery (EOR) applications where it is used for solubilization and mobilization of oil and for environmental cleanup. Further, the hydrophobe alkoxylated GA without anionic terminal group can be used as an ultra-high molecular weight non-ionic surfactant.

Abstract: A method according to an embodiment of the present invention infers a network of information dependence in real-time by capturing the manner in which computer users interact with files. For example, in an embodiment, such dependencies are represented as a sparse directed network. In another embodiment of the present invention, In another embodiment of the present invention, the dependencies are embedded in an operating system or document management system at a level commensurate with the manner in which professionals use Windows Explorer.

Abstract: Various embodiments provide a bioreactor for producing a bioproduct comprising a housing; and one or more catalytically active zones located in the housing and adapted to keep two incompatible gaseous reactants separated when in a gas phase, wherein each of said catalytically active zone comprises a catalytic component retainer and a catalytic component retained within and/or on the catalytic component retainer. Each of said catalytically active zones may additionally or alternatively comprise a liquid medium located on either side of the catalytic component retainer and the catalytic component may additionally or alternatively be a suspended catalytic component suspended in a liquid medium located on either side of the catalytic component retainer. Methods of using various embodiments of the bioreactor to produce a bioproduct, such as isobutanol, are also provided.

Abstract: Provided herein are diagnostic markers and uses thereof for predicting if a subject is at risk of a major adverse event. In particular, one aspect provided herein relates to methods to determine if a subject is at risk of having a major adverse effect by measuring at least 2, or at least 3 of the biomarkers beta 2 microglobulin, c-reactive protein and cystatin C.

Abstract: Methods of treatment in subjects suffering from diabetes mellitus or obesity are provided. The methods comprise the step of administering an active agent directly to the small intestine in the subject. In particular, the active agent may be administered directly to the duodenum in the subject. The active agents useful in the treatments described herein include analgesic agents and, in particular, antinociceptive agents such as capsaicin, resiniferatoxin, and their analogues.

Abstract: The present application provides, among other things, compounds, compositions and methods for treating various diseases including cancer.

Abstract: A method, system and computer program product for efficiently identifying images, videos, audio files or documents relevant to a user. Using either manual annotations or learned functions, the method predicts the relative strength of an attribute in an image, video, audio file or document from a pool of images, videos, audio files or documents. At query time, the system presents an initial set of reference images, videos, audio files or documents, and the user selects among them to provide relative attribute feedback. Using the resulting constraints in the multi-dimensional attribute space, the relevance function for the pool of images, videos, audio files or documents is updated and the relevance of the pool of images, videos, audio files or documents is re-computed. This procedure iterates using the accumulated constraints until the top-ranked images, videos, audio files or documents are acceptably close to the user's envisioned image, video, audio file or document.

Abstract: In various embodiments, the present disclosure provides a method of fixing nitrogen. An amount of titania catalyst is provided and contacted with a feed stream that includes nitrogen. The titania catalyst is heated. The heated titania catalyst fixes nitrogen in the feed stream to form nitrogen products, such as nitrates. The nitrogen products are then removed from the titania catalyst. In some examples, the titania catalyst is treated with a base. In further examples, the catalytic process is carried out in the absence of light for photochemically activating the titania catalyst.