Patents Assigned to Board of
  • Publication number: 20140147849
    Abstract: Methods are provided for determining, in a single polymerase chain reaction (PCR) reaction, the quantity, quality, and gender of origin of DNA in a sample, and whether or not the sample contains PCR amplification inhibitors. The methods involve carrying out a single PCR multiplex reaction utilizing primer sets specific for amplifying: the human amelogenin locus; an X- and/or Y-chromosome specific gene that is shorter than the amelogenin gene; at least one mitochondrial DNA sequence, and preferably two differently-sized mitochondrial sequences; and a heterologous, non-human reporter gene.
    Type: Application
    Filed: September 21, 2011
    Publication date: May 29, 2014
    Applicant: The Board of Regents for Oklahoma State University
    Inventor: Robert W. Allen
  • Publication number: 20140147747
    Abstract: A three-dimensional porous electrode architecture for a microbattery includes a substrate having first and second conductive patterns disposed thereon where the first and second conductive patterns are electrically isolated from each other, a three-dimensional porous cathode disposed on the first conductive pattern, and a three-dimensional porous anode disposed on the second conductive pattern. The porous cathode includes a first conductive scaffold conformally coated with a layer of a cathode active material and having a porosity defined by a network of interconnected pores, where the first conductive scaffold has a lateral size and shape defined by the first conductive pattern and porous side walls oriented substantially perpendicular to the substrate. The porous anode includes a second conductive scaffold conformally coated with a layer of an anode active material and having a porosity defined by a network of interconnected pores.
    Type: Application
    Filed: July 25, 2012
    Publication date: May 29, 2014
    Applicant: The Board of Trustee of the University of Illinois
    Inventors: William P. King, PAul V. Braun, JAmes H. Pikul
  • Publication number: 20140147996
    Abstract: Solvent mixtures useful for processing bulk heterojunction materials and methods for selecting the same are disclosed, wherein Hansen solubility parameters are utilized to select the solvent mixture. A solvent system using a fully nonhalogenated solvent mixture is disclosed. Also disclosed is a solvent mixture containing 20 vol. % acetophenone (AP) in mesitylene (MS), wherein the performance of the solvent system is comparable to dichlorobenzene.
    Type: Application
    Filed: November 28, 2011
    Publication date: May 29, 2014
    Applicant: Arizon Board of Regents Acting for and on Behalf Arizona State University
    Inventors: Bryan D. Vogt, Jian Li, Choong-Do Park
  • Publication number: 20140144517
    Abstract: Apparatus and methods for forming and propagating a plurality of plasma armatures along electrodes. In particular embodiments, the electrodes are flush mounted to the surface and the plasma armatures are formed and propagated at a high frequency and velocity.
    Type: Application
    Filed: August 8, 2013
    Publication date: May 29, 2014
    Applicant: Board of Regents, The University of Texas System
    Inventors: Laxminarayan RAJA, Jayant SIROHI, Mark CRAWFORD, Francesco STEFANI
  • Publication number: 20140148880
    Abstract: Provided herein are compositions comprising lanthanide-doped nanoparticles which upconvert electromagnetic radiation from infrared or near infrared wavelengths into the visible light spectrum. Also provided herein are methods activating light-responsive opsin proteins expressed on plasma membranes of neurons and selectively altering the membrane polarization state of the neurons using the light delivered by the lanthanide-doped nanoparticles.
    Type: Application
    Filed: November 4, 2011
    Publication date: May 29, 2014
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Karl Deisseroth, Polina Anikeeva
  • Publication number: 20140148351
    Abstract: Methods, compositions, and kits are provided for providing a diagnosis, a prognosis, or a prediction of responsiveness to a therapy for a patient with a hematological malignancy. In practicing the subject methods, the expression level of at least one leukemia stem cell (LSC) genes in a tissue sample is assayed to obtain an LSC expression representation. The LSC expression representation is then employed to determine if an individual has a hematological malignancy, to provide a prognosis to a patient with a hematological malignancy, and/or to provide a prediction of the responsiveness of a patient with a hematological malignancy to a therapy. Also provided are screening methods for identifying novel therapies for patients with a hematological malignancy, and compositions and kits for use in these screening methods.
    Type: Application
    Filed: September 28, 2011
    Publication date: May 29, 2014
    Applicant: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Arash Ash Alizadeh, Ravindra Majeti, Andrew J. Gentles
  • Patent number: 8735633
    Abstract: A method comprising reacting glycerol with acetaldehyde or 1,1-diethoxyethane to produce 1,3-dihydroxyacetone (DHA), without using fermentation or direct oxidation of the glycerol is provided. DHA is useful in various products, including as a sunless tanning agent.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: May 27, 2014
    Assignee: Board of Trustees of Michigan State University
    Inventors: Dennis Miller, Xi Hong, Carl Lira, Omar McGiveron
  • Patent number: 8734968
    Abstract: A microbial fuel cell includes an anode portion having an anode and a cathode portion having a cathode. The anode is configured to support an electrically conductive biofilm matrix. A cation exchange membrane is positioned between the anode and the cathode. The anode portion and the cation exchange membrane define an anode chamber having a volume of between about 1 ?L and about 100 ?L and configured to receive an anolyte. The cathode portion and the cation exchange membrane define a cathode chamber having a volume of between about 1 ?L and about 100 ?L and configured to receive a catholyte. The microbial fuel cell is configured to achieve a Coulombic efficiency of at least 30% and/or a power density of at least of 4.7 ?W/cm2. The microbial fuel cell is a microelectromechanical system and can be fabricated in an automated production process.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: May 27, 2014
    Assignee: Arizona Board of Regents, a body corporated of the State of Arizona acting for and on behalf of Arizona State University
    Inventors: Junseok Chae, Bruce E. Rittmann, Seokheun Choi, Hyung-Sool Lee
  • Patent number: 8735066
    Abstract: A specific region of chromosome 10 (10q23.3) has been implicated by series of studies to contain a tumor suppressor gene involved in gliomas, as well as a number of other human cancers. One gene within this region was identified, and the corresponding coding region of the gene represents a novel 47 kD protein. A domain of this product has an exact match to the conserved catalytic domain of protein tyrosine phosphatases, indicating a possible functional role in phosphorylation events. Sequence analyses demonstrated the a number of exons of the gene were deleted in tumor cell lines used to define the 10q23.3 region, leading to the classification of this gene as a tumor suppressor. Further analyses have demonstrated the presence of a number of mutations in the gene in both glioma and prostate carcinoma cells. Methods for diagnosing and treating cancers related to this tumor suppressor, designated as TS10q23.3, also are disclosed.
    Type: Grant
    Filed: April 23, 2012
    Date of Patent: May 27, 2014
    Assignee: Board of Regents, The University of Texas System
    Inventors: Peter Steck, Mark A. Pershouse, Samar A. Jasser, Alfred W. K. Yung, Sean V. Tavtigian
  • Patent number: 8734808
    Abstract: Vaccines preparations against canine parvovirus are provided. The vaccines include a novel canine parvovirus-2 isolated from a raccoon, and related nucleic acids and proteins.
    Type: Grant
    Filed: October 14, 2010
    Date of Patent: May 27, 2014
    Assignee: The Board of Regents for Oklahoma State University
    Inventor: Sanjay Kapil
  • Patent number: 8733149
    Abstract: The present invention relates generally to the detection of alcohol. The present invention relates more particularly to the film bulk acoustic wave resonator-based devices, and their use in the sensing of ethanol and/or acetone. One aspect of the invention is a method for detecting ethanol, acetone or both in a gaseous sample including: providing a film bulk acoustic wave resonator having a zinc oxide piezoelectric layer; exposing the film bulk acoustic wave resonator to the gaseous sample; determining the resonant frequency of the film bulk acoustic wave resonator; and determining the concentration of ethanol, the concentration of acetone, or both in the gaseous sample using the resonant frequency of the film bulk acoustic wave resonator.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: May 27, 2014
    Assignee: Arizona Board of Regents, a body corporate of the State of Arizona, Acting for and on Behalf of Arizona State University
    Inventors: Hongyu Yu, Xiaotun Qiu
  • Patent number: 8735096
    Abstract: Engineered fusion proteins comprising photochromic protein domains are disclosed. In particular, the inventors have constructed fusion proteins containing photoswitchable photochromic fluorescent protein domains linked to selected proteins and shown that such fusion proteins can be used to control the activity or localization of selected proteins with light.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: May 27, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Xin Zhou, Michael Z. Lin
  • Patent number: 8735609
    Abstract: Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or improved recognition domains are disclosed, including methods of preparing and utilizing the same.
    Type: Grant
    Filed: October 23, 2012
    Date of Patent: May 27, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Paul A. Wender
  • Patent number: 8735828
    Abstract: Apparatus and methods for measuring radiation levels in vivo in real time. Apparatus and methods include a scintillating material coupled to a retention member.
    Type: Grant
    Filed: January 7, 2010
    Date of Patent: May 27, 2014
    Assignee: The Board of Regents of the University of Texas System
    Inventors: A. Sam Beddar, Tina Marie Briere, Louis Archambault
  • Patent number: 8733721
    Abstract: A board mount which can be utilized to position a board relative to a building element. In various embodiments, the board mount can include a holder for receiving at least a portion of a drywall board and, in addition, a flexible member which can be inserted intermediate first and second building elements to retain the board holder relative to one of the first and second building elements. The flexible member can be configured to be deflected, or flexed, between a first configuration and a second configuration when the flexible member is positioned intermediate the building elements. In use, the flexible member can hold the board mount in place while a laborer inserts the drywall board into the board holder. In such circumstances, an additional laborer may not be required to hold the drywall board in position as it is fastened, or otherwise secured, to the frame of the building.
    Type: Grant
    Filed: January 8, 2008
    Date of Patent: May 27, 2014
    Assignee: Board Mount Inc.
    Inventors: Marc D. Lacerte, Richard Nadeau, Trevor Duhaime
  • Patent number: 8738524
    Abstract: An automated system for creating parity on close orders in an exchange configured for trading securities or derivatives is disclosed including an electronic trade engine operative to receive an order for a security or derivative at the exchange, the trade engine further operative to disseminate a request for a price message to a plurality of market makers quoting a class in response to receiving the order, wherein the request for a price message includes a parity amount for the order; an electronic book in communication with the electronic trade engine, the electronic book operative to store at least one order received by the electronic trade engine; and wherein, in response to the request for a price message, the electronic trade engine receives at least one price message that includes a fee in addition to the parity amount.
    Type: Grant
    Filed: June 24, 2011
    Date of Patent: May 27, 2014
    Assignee: Chicago Board Options Exchange, Incorporated
    Inventors: Matthew McFarland, John Joseph Wiesner
  • Patent number: 8735286
    Abstract: A method for sealing through-holes in a material via material diffusion, without the deposition of a sealant material, is disclosed. The method is well suited to the fabrication and packaging of microsystems technology-based devices and systems. In some embodiments, the method comprises forming sacrificial material release through-holes through a structural layer, removing the sacrificial material via an etch that etches the sacrificial material through the release through-holes, and sealing of the release through-holes via material diffusion.
    Type: Grant
    Filed: October 28, 2011
    Date of Patent: May 27, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Rishi Kant, Roger Thomas Howe
  • Patent number: 8735102
    Abstract: The present invention relates to a recombinant Bacillus host cell containing a recombinant vector including a nucleic acid segment having a coding region segment encoding enzymatically active hyaluronan synthase (HAS). The recombinant Bacillus host cell is utilized in a method for producing hyaluronic acid (HA).
    Type: Grant
    Filed: July 5, 2011
    Date of Patent: May 27, 2014
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Paul L. DeAngelis, Paul H. Weigel, Kshama Kumari
  • Patent number: 8735440
    Abstract: This technology relates generally to compounds and methods for stimulating neurogenesis (e.g., post-natal neurogenesis, including post-natal hippocampal and hypothalamic neurogenesis) and/or protecting neuronal cell from cell death. Various compounds are disclosed herein. In vivo activity tests suggest that these compounds may have therapeutic benefits in neuropsychiatric and/or neurodegenerative diseases such as schizophrenia, major depression, bipolar disorder, normal aging, epilepsy, traumatic brain injury, post-traumatic stress disorder, Parkinson's disease, Alzheimer's disease, Down syndrome, spinocerebellar ataxia, amyotrophic lateral sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of a neuro-active drug, retinal degeneration, spinal cord injury, peripheral nerve injury, physiological weight loss associated with various conditions, as well as cognitive decline associated with normal aging, chemotherapy, and the like.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: May 27, 2014
    Assignee: Board of Regents of The University of Texas System
    Inventors: Steven L. McKnight, Andrew A. Pieper, Joseph M. Ready, Jef K. De Brabander
  • Patent number: 8734853
    Abstract: Disclosed are high density lipoprotein-nucleic acid particles, wherein the particles include (a) an apolipoprotein; (b) a nucleic acid component comprising a therapeutic nucleic acid segment; and (c) a polypeptide comprising a positively charged region, wherein the positively-charged region of the polypeptide associates with the nucleic acid component. Also disclosed are pharmaceutical compositions that include a) an apolipoprotein; (b) a nucleic acid component comprising a therapeutic nucleic acid segment; and (c) a polypeptide comprising a positively charged region. Methods that concern the particles and pharmaceutical compositions of the present invention are also set forth, as well as kits.
    Type: Grant
    Filed: November 17, 2009
    Date of Patent: May 27, 2014
    Assignees: University of North Texas Health Science Center at Fort Worth, The Board of Regents, The University of Texas System
    Inventors: Anil K. Sood, Andras G. Lacko, Gabriel Lopez-Berestein, Lingegowda S. Mangala, Walter J. McConathy, Laszlo Prokai, Maya P. Nair