Abstract: A unitary snap hinge made of plastic with two hinge parts which are connected with each other by means of a main joint. A flexible connecting piece is connected with the hinge parts by means of secondary joints, whereby the secondary joints have a distance from the main joint transverse to the joint axis and that the joints are designed as film joints. The hinge parts have the tendency to snap into the one or other end position from a position of an unsteady balance within their own pivot range. The snap hinge is a separate structural element. The one hinge part supports a locking element for a removal opening, the other hinge part supports at least one adapter piece with arresting elements. Thereby, the snap hinge can be mounted on a container or on the locking piece of the same.

Abstract: Control serum containing (1) at least one compound of the formula: ##STR1## in which T is hydrogen or methyl, hydroxymethyl or methoxymethylX is hydrogen hydroxymethyl or methyl when Y is hydroxyl, hydroxymethyl or NR.sub.2 ;Y is hydrogen, hydroxyl, hydroxylmethyl or NR.sub.2 andZ is hydroxyl or an --O--CH.sub.2 --CH.sub.2 OH group when Y is hydrogen or hydroxymethyl, or Z is hydroxymethyl or a carboxyl derivative orT is ethyl or isopropyl,X is hydrogen, or methyl, hydroxymethyl or methoxy,Y is hydroxy, hydroxymethyl or NR.sub.2 andZ is a carboxyl derivative;each R independently is hydrogen or an alkyl group with 1 to 2 carbon atoms optionally containing a hydroxy group and/or (2) at least one compound of the formulaHO(CH.sub.2 --CH.sub.2 --O).sub.n H, (II)in which n is an integer from 2 to 8,in an amount sufficient to reduce turbidities in reconstituted serum after previous lyophilization.

Abstract: The present invention provides new pyrrolobenzimidazoles of the general formula: ##STR1## wherein R.sub.1 is a hydrogen atom or an alkyl, alkenyl or cycloalkyl radical; R.sub.2 is a hydrogen atom, cyano group or alkyl or alkenyl radical or a carbonyl group substituted by hydroxyl, alkyl, alkoxy, amino, alkylamino, dialkylamino or hydrazino or together with R.sub.1 forms a cycloalkylene radical or R.sub.1 and R.sub.2 together form an alkylidene or cycloalkylidene radical; R.sub.3, R.sub.4 and R.sub.

Abstract: The present invention provides a process for the determination of fibrin monomer in plasma, wherein a plasma sample containing fibrin monomer and freed from plasmin inhibitors is incubated in buffered solution with tissue plasminogen activator (EPA), plasminogen and a chromogenic plasmin substrate and the color formed is measured as a measure of the amount of fibrin monomer.The present invention also provides a reagent for the determination of fibrin monomer in plasma, wherein it contains plasminogen, tissue plasminogen activator (EPA), chromogenic plasmin substrate and buffer (pH 7.0 to 9.0).

Abstract: A drill stop apparatus for use with an elongated drill bit is provided. The drill bit has a drilling end that is used to drill a hole of a specified, predetermined depth. The bit also has a plurality of circumferentially extending, axially spaced grooves formed on its outer surface. The drill stop includes a body having a first end and formed to include an axially extending bore that is sized to receive the drill bit to permit the bit to be moved axially within the body. The body also has a cavity that extends substantially perpendicularly through the bore. A plunger is provided that is sized to be received in the cavity for releasably engaging one of the plurality of grooves in the drill bit to lock the drill bit against axial movement within the body member such that a specified length of the drill bit extends beyond the first end of the body member.

Abstract: The present invention provides compounds of the general formula: ##STR1## in which R and R.sub.1, independently of one another, each represent a straight-chained or branched alkyl or alkoyl radical containing up to 6 carbon atoms or a phenyl radical or R and R.sub.1 together also form a methylene bridge, the hydrogen atoms of which, independently of one another, can each be substituted by an alkyl radical containing up to 5 carbon atoms or a phenyl radical, R.sub.2 represents an oligoglucoside residue containing 2 to 7 glucose units and X is a hydrogen atom or an optically-determinable residue.The present invention also provides a process for the preparation of these compounds.

Abstract: The present invention provides an agent for the removal of a turbidity in a biological fluid, wherein it contains(a) a polyethoxylated triglyceride with an HLB value of 4 to 14,(b) a secondary n-alkane sulphonate, as well as optionally(c) a futher non- or anionic tenside, in aqueous, optionally buffered solution.

Abstract: The present invention provides a process for the determination of glycerol in free or bound form by reaction with ATP in the presence of glycerol kinase (GK) and optionally of a hydrolase with the formation of glycerol-3-phosphate and ADP and determination of one of these reaction products with the help of at least one subsequent enzymatic reaction, wherein the determination is carried out kinetically and, for this purpose, the reaction with ATP is made rate-determining for the whole reaction and this is allowed to proceed according to the pseudo-first order in that there is added a sugar of the general formula: ##STR1## in which carbon atoms 2 and 3 have the D-threo configuration and R is a carbohydrate radical containing up to 3 carbon atoms and in which one hydroxyl group can also be replaced by a hydrogen atom.

Abstract: The present invention is concerned with the use of adenosine derivatives for the treatment of allergic diseases, as well as for bronchosphatic and broncho-constrictive reactions brought about by inflammation. The above adenosine derivatives can be used alone or together with xanthine derivatives. The invention is further concerned with compositions containing compounds of adenosine derivatives and optionally compounds of xanthine derivatives together with appropriate pharmaceutical carriers.

Abstract: The present invention provides a control or calibration serum for lipid diagnosis, wherein it contains the parameters relevant for lipid diagnosis in the normal or pathological concentration range in a single storage-stable form.The present invention also provides processes for the preparation of this control or calibration serum.

Abstract: A process for the preparation of S- or R-carbazole derivatives of the general formula: ##STR1## in which R is an unsubstituted or substituted amino radical and pharmacologically acceptable salts, by either reacting R-(-)-epichlorohydrin (for the S-carbazole derivative); or reacting an S-epoxide derivative of the general formula: ##STR2## in which R.sub.1 is the residue of a substituted sulphonic acid derivative (for the R-carbazole derivative); with 4-hydroxycarbazole and then with ammonia or a substituted amine of the general formula RH, and recovering the compound or converting it to a pharmacologically acceptable salt.The new R-(+)- and S(-)-carbazole derivatives provided by the inventive process have unexpected beta blocking and vasodilatory properties and are useful in pharmaceutical compositions. R-(+)-carbazole derivatives are also useful for the treatment of glaucoma.

Abstract: The present invention provided pyrrolobenzimidazoles or tautomer thereof, of the general formula: ##STR1## wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl or C.sub.3 -C.sub.7 cycloalkyl;R.sub.2 is hydrogen, cyano, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl, or a carbonyl group substituted by hydroxyl, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkyoxy, amino, C.sub.1 -C.sub.6 alkylamino, C.sub.2 -C.sub.12 dialkylamino or hydrazino, orR.sub.2 and R.sub.1 together with the carbon to which they are attached form a C.sub.3 -C.sub.8 spirocycloalkyl ring, or R.sub.1 and R.sub.2 together form C.sub.3 -C.sub.7 alkylidene or C.sub.3 -C.sub.7 cycloalkylkidene,X is a valency bond, C.sub.1 -C.sub.

Abstract: The present invention provides a process for the determination of the hemoglobin-haptoglobin complex in the presence of free hemoglobin by utilization of the different peroxidate properties of free and of bound hemoglobin, wherein, for the selective inhibition of the peroxidase activity of the free hemoglobin, a detergent is added and the residual peroxidate activity of the reaction mixture is measured.The present invention also provides a reagent for carrying out this process wherein, besides the substances required for the determination of the peroxidase activity, it contains a detergent for the inhibition of the peroxidase activity of free hemoglobin.Furthermore, the present invention provides a process for determining the haptoglobin content of a sample, as well as a process for determining glycosilated hemoglobin in a sample.

Abstract: A relative position detector has a photodetector arrangement for providing light and responding to the intensity of the light when reflected thereto. A member such as a cylindrical pin having a surface reflective of the light, convex to the photodetector arrangement, and movable relative thereto reflectively sweeps the light across the photodetector arrangement for responding thereto to produce a continuously-curving response indicating with its peak the position detected. The continuously-curving response can be differentiated in a peak detector for even more precise position detection. A mount which may be used for the photodetector arrangement has a support member and a member having a lower coefficient of thermal expansion slidably supported thereon, except for one fixed point.

Abstract: The present invention provides a restriction endonuclease, characterized by the palindromic recognition sequence: ##STR1## and the cleavage position defined by the arrows. The present invention also provides a process for obtaining the new restriction endonuclease.

Abstract: The present invention provides a restriction endonuclease, characterized by the palindromic recognition sequence: ##STR1## and the cleavage position defined by the arrows. The present invention also provides a process for obtaining this new restriction endonuclease.

Abstract: The present invention provides a restriction endonuclease, characterized by the palindromic recognition sequence: ##STR1## and the cleavage position defined by the arrows. The present invention also provides a process for obtaining this new restriction endonuclease.

Abstract: The present invention provides a process for the simultaneous determination of fibrinogen and fibrinogen fission products in plasma, wherein 0.01 to 1 U of a snake venom enzyme with a thrombin-like effectiveness is aded per ml. of sample plasma, then there is measured the period of time between the addition of the enzyme and the commencement of a turbidity formation as a measure for the amount of fibrinogen fission products and subsequently there is measured the speed of the turbidity formation as a measure of the amount of fibrinogen.The present invention also provides a reagent for the simultaneous determination of fibrinogen and fibrinogen fission products, wherein it comprises 0.01 to 10 U snake venon enzyme with thrombin-like effectiveness per ml. of sample plasma, 0.5 to 4% by weight of a water-soluble polyalcohol, 1 to 20 mMole/liter of calcium ions and 0.05 to 0.3 mole/liter of buffer of pH 7.0 to 8.0, referred to the solution ready for use, as well as optionally a detergent.

Abstract: In a process for carrying out an analytical determination by mixing and incubating a sample liquid with at least one dry reagent which is soluble therein to form a reaction mixture liquid and measuring a parameter in the reaction mixture liquid, the sample liquid is first transported along a transport path to the soluble dry reagent and the resulting reaction mixture liquid then further transported along the transport path. The further transporting of the reaction mixture liquid along the transport path is under the influence of a force-change cycle in which centrifugal force and a further force alternately predominate to determine the direction of the further transporting along the transport path. At least one further liquid is transported on another path, part of which is separate from and part of which is common with the transport path, by the force-change cycle in such a manner that at least two of the liquids pass through the common part of the transport path chronologically separated.

Abstract: A submergible, post-type dental implant system for anchoring an artificial crown or bridge in a row of teeth or edentulous or partially edentulous area includes a root structure which is surgically implanted transgingivally and into the bone therebeneath, an implant head which is compatibly sized and shaped to fit over an upper tapered portion of the root structure. Prior to the assembly of these two titanium alloy components, a healing cap is disposed over the tapered portion of the root structure during the time interval for healing which may be as much as three to six months. After the healing periods has ended, a tool is used to remove the healing cap and thereafter the implant head is aligned and slid over the top tapered portion of the root structure.