Abstract: A medical device may include a handle assembly having an actuator and a sheath. The sheath may extend between a proximal end and a distal end. The proximal end of the sheath may be coupled with the actuator. The medical device may further include an end-effector moveable relative to the sheath between an extended configuration and a retracted configuration. The end-effector may include a plurality of expandable legs. Each of the plurality of expandable legs may include a plurality of first indicia and a plurality of second indicia. A color of each of the first plurality of indicia may be different than a color of each of the second plurality of indicia.

Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to medical devices and systems with control knobs designed for improved usability and ergonomics. For example, the control knobs of the present disclosure may include surface features for improved gripping, surface features for improved perception of medical device orientation within a patient and/or knobs dimensioned for improved thumb reach and reduced torque.

Abstract: A clipping system includes an adapter mounted on an insertion device and a clip including first and second jaws connected via hinges so that the first and second jaws are movable between an insertion configuration and an initial deployed configuration. A deployment member is configured to move the clip distally over and off of the adapter so that, as the clip leaves the adapter, the clip moves from the insertion configuration to the initial deployed configuration. An extending member is releasably coupled to the clip and movably connected to the adapter, and is configured to permit the withdrawal of the adapter away from the clip while the extending member remains coupled to the clip to place the system in a review configuration. The extending member is operable to retract the clip over the adapter, freeing the clip from tissue on which it had been clipped.

Abstract: A suction device configured to simultaneously draw in fluid and expel fluid. The suction device may comprise a barrel defining a cavity and extending from a first end to a second end. A first fluid inlet may be adjacent the first end of the barrel and a second fluid inlet adjacent the second end of the barrel and a first fluid outlet may be adjacent the first end of the barrel and a second fluid outlet adjacent the second end of the barrel. A plunger may be slideably disposed within the cavity of the barrel with a handle assembly operably coupled thereto. A actuation of the handle assembly may be configured to move the plunger within the cavity between the first end and the second end of the barrel.

Abstract: A method and apparatus are disclosed for regulating a temperature of an esophagus when heat or cold is delivered to a left atrium, the method including altering a heat exchange device from an insertable configuration to a heat exchanging configuration which conforms and corresponds with a cross-section of an inside of the esophagus such that the esophagus is maintained in its natural shape and location. In some embodiments the heat exchange device has a heating/cooling balloon which is inflated to be in the heat exchanging configuration. Some alternative embodiments includes altering the configuration of the balloon to conform to or correspond with the cross section of an esophagus by means other than inflation.

Abstract: An electrosurgical device for puncturing tissue comprises an electrically conductive elongate member which is capable of force transmission from a distal portion of the electrosurgical device to a proximal portion of the electrosurgical device to thereby provide tactile feedback to a user. The proximal portion comprises a connector system for connecting a source of energy and a source of fluid to an electrosurgical device. The connector system includes a hub which includes an electrically conductive lengthwise member having a lengthwise member distal region and a lengthwise member proximal region. The lengthwise member defines a hub lumen therebetween and is configured to be operatively coupled to an electrosurgical device.

Abstract: A medical device includes a handle, a shaft extending from the handle, and an articulation member integral with or attached to a distal end of the shaft. The articulation member includes a first portion coupled to a second portion, the second portion is receivable in a slot defined by the first portion, and the handle is coupled to each of the first portion and the second portion and to articulate the first portion independently of articulating the second portion.

Abstract: A transseptal system can include a guidewire, a dilator, and a deflectable sheath configured to safely deliver a puncture needle through a septal wall associated with the fossa ovalis and into a central region of the left atrium of a heart. The dilator can include a dilator nose having a first outer diameter and a dilator beveled segment, extending proximal of the dilator nose, tapering from a second, greater outer diameter to the first outer diameter. The length and interplay of the puncture needle and the dilator nose can be configured such that the puncture needle is inhibited from bending and impinging upon the left side of the atrial septum of the heart during use. A body of the guidewire can include at least one loop segment to provide stable support in the left atrium for delivery of a diagnostic or therapeutic device along its more proximal portions. The deflectable sheath can position and align the dilator nose relative to the fossa ovalis.

Abstract: A medical device may include a handle and an end cap. The handle may include a first movable body and a stationary body. The end cap may include an outer portion, an inner portion disposed within the outer portion, and at least one biasing member. The outer portion may define a receptacle configured to contain a material. The inner portion may be proximal to the receptacle, within the outer portion, and coupled to the first movable body by at least one control element. The biasing member(s) may be disposed between a proximal face of the inner portion and a distal face of a proximal wall of the outer portion. Accordingly, movement of the first movable body relative to the stationary body moves the inner portion relative to the outer portion. Movement of the inner portion may be configured to deliver the material.

Abstract: A medical device, for example a delivery catheter, may include a handle portion, a shaft portion extending distally from the handle portion, a deployment mechanism, and an actuation member positioned on the handle portion. The shaft portion may include a working channel and a distal tip portion having a payload chamber configured to receive a payload, such as a bio-absorbable foam. The distal tip portion may be operatively connected to the working channel. The deployment mechanism may be positioned in the working channel, and may be operable to deploy the payload out from the distal tip portion. The actuation member may be actuatable to operate the deployment mechanism.

Abstract: A medical device includes a handle with a proximal arm and a distal arm. The proximal arm and the distal arm are pivotable via a joint. The medical device also includes a tube coupled to the distal arm and a drive wire. A distal portion of the drive wire includes an expandable end effector. A portion of the drive wire is positioned within the tube, and a different portion of the drive wire extends proximally of the distal arm and is coupled to the proximal arm.

Abstract: An introducer sheath including a valve hub and an elongate shaft extending from the valve hub. The valve hub defines a main port and a side port. The main port includes a hub body, a seal disposed within the hub body, a main port lid attached to the hub body, a tightening port hub attached to the main port lid, a compressible seal disposed within a lumen of the tightening port hub, a pusher at least partially positioned within the lumen of the tightening port hub and slidably movable relative thereto, and a lock nut surrounding the pusher. The lock nut is threadably engaged with the tightening port hub such that rotation of the lock nut moves the pusher axially toward and/or away from the compressible seal.

Abstract: An introducer sheath including a valve hub and an elongate shaft extending from the valve hub. The valve hub defines a main port and a side port. The main port includes a hub body, a compressible seal disposed within the hub body, a pusher at least partially positioned within the hub body and slidably movable relative thereto, and a lock nut surrounding the pusher. The lock nut is threadably engaged with the hub body such that rotation of the lock nut moves the pusher axially toward and/or away from the compressible seal.

Abstract: Medical systems and methods of use thereof useful to image the body are described. The medical system may include a first medical device defining a channel between a proximal end and a distal end of the first medical device; and a second medical device including a tube, a plunger, and a needle. A distal portion of the tube may include an imager, and the needle may be translatable along the tube relative to the plunger. The second medical device may be insertable in, and translatable along, the channel of the first medical device.

Abstract: The present disclosure relates generally to the field of medical devices such as endoscopes, endoscope assemblies, guide tubes, introducers, and instrument caps for endoscopes, guide tubes, and introducers. In particular, the present disclosure relates to biopsy cap configurations providing scalable access for medical instruments to a working channel, such as a working channel for an endoscope.

Abstract: A medical device may comprise a handle having a fluid source, a conduit coupled to the handle, and a distal portion coupled to a distal end of the conduit. The distal portion may comprise an outer portion defining a lumen and an inner portion. The inner portion may be disposed within the lumen if the outer portion. The inner portion may define a cavity having a distal opening. The cavity may be configured to contain a material. In a first configuration of the distal portion, the material is disposed within the inner portion. Delivery of a fluid from the fluid source into the lumen of the outer portion transitions the distal portion from the first configuration to a second configuration and causes the inner portion to move distally relative to the outer portion and deliver at least a portion of the material.

Abstract: Devices, systems, and methods for combining and/or delivering an injectable material to a patient. A vial adaptor is configured to fluidly couple at least a first chamber and a separate chamber and to facilitate fluid exchange therebetween as well as to vent the separate chamber as material is withdrawn therefrom. The first chamber may be defined in a multi-chamber device which further defines a second chamber. The vial adaptor further defines a purge reservoir into which excess material and/or air may be purged from the second chamber. For instance, as material is ejected from the first chamber into the separate chamber, a determined amount of material may be purged from the second chamber into the purge reservoir.

Abstract: Mixing systems for producing a mixture to deliver to a treatment site. An illustrative system may comprise a needle hub, a multi-reservoir system, and a syringe. The multi-reservoir system may comprise a plunger assembly including a first plunger and a second plunger, a barrel portion including a housing defining a first reservoir in fluid communication with a first port and configured to contain a first constituent and a second reservoir configured to contain a second constituent and in fluid communication with a second port, and a cap including a port and a lumen extending therethrough. A third constituent may be injected from the syringe into the first reservoir via the port of the cap to form a precursor. Actuating the plunger assembly relative to the barrel portion may cause the precursor and the second constituent to be delivered into the needle hub.

Abstract: Devices, systems, and methods for combining and/or delivering an injectable material to a patient. A first device having a first nozzle is moved rotationally and/or generally axially with respect to a second device having a first nozzle port to seat the first nozzle with respect to the first nozzle port. The second device has a nozzle pocket positioned, sized, shaped, configured, and/or dimensioned with respect to the first nozzle port to guide axial and/or rotational relative movements of the first injectable material transfer device and the second injectable material transfer device to guide the first nozzle into alignment with the first nozzle port, such as to be seated with respect to the first nozzle port.

Abstract: A multi-chamber device having a barrel with a first chamber and a second chamber, and a plunger assembly with a first plunger rod advanceable with respect to the first chamber and a second plunger rod advanceable with respect to the second chamber. The ends of the first and second plunger rods are independently advanceable to advance different amounts of material from the first and second chamber as the plunger assembly is advanced with respect to the barrel. The multi-chamber device may be part of a multi-chamber system including an injection system. The multi-chamber device and the injection system may include engaging elements facilitating ready coupling and decoupling of the multi-chamber device and the injection system.