Patents Assigned to BRUKER BIOSPIN
  • Publication number: 20120025832
    Abstract: An antenna configuration for use in a magnetic resonance apparatus, which is designed as phase-controlled array and comprises at least two individual antennas which each comprise at least one conductor loop, one tuning network and one matching network, wherein the tuning network contains at least one tuning capacitance and the matching network contains at least one matching capacitance, and the individual antennas are each combined into separate modules which are positioned on and mounted to a support body and can be removed therefrom in a non-destructive fashion, is characterized in that the individual antennas are connected to each other through decoupling elements, wherein the decoupling elements are mounted to the support body in an undetachable fashion.
    Type: Application
    Filed: July 27, 2011
    Publication date: February 2, 2012
    Applicant: Bruker BioSpin AG
    Inventor: Daniel Schmidig
  • Patent number: 8098069
    Abstract: A closed container having a single opening is sealed by a plug fabricated from a self-sealing elastomer. Before insertion, the plug is transfixed with a tube to allow air to escape as the plug is pushed into the container. The plug and tube are then inserted into a container. After the plug has been seated in the container, the tube is withdrawn, allowing the self-sealing elastomeric material to close the canal formed by the tube and to form a hermetic seal.
    Type: Grant
    Filed: April 17, 2009
    Date of Patent: January 17, 2012
    Assignee: Bruker Biospin Corporation
    Inventors: Eckhard Bez, Melanie Rosay
  • Patent number: 8085122
    Abstract: A high voltage step-up power transformer includes at least one module which defines a lower voltage primary side and a higher voltage secondary side and which includes at least one primary winding and at least one secondary winding, wound concentrically around a ferromagnetic core body, the primary winding(s) being situated outwardly, and at least one shielding and/or insulating surface structure being arranged between the primary and secondary windings. The transformer (1) is characterized in that the outer primary winding (2) or winding parts is (are) made of at least one insulated high voltage cable and in that the at least one conductive intermediate surface structure (5) and/or the core body (4) are set at a referential potential which is a fraction of the output voltage or potential difference on the secondary side.
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: December 27, 2011
    Assignee: Bruker Biospin SA
    Inventor: Alfred Niess
  • Patent number: 8082127
    Abstract: A method for determining the spatial distribution of magnetic resonance signals from an imaging area, wherein nuclear spins are excited in a spatially encoded fashion through multi-dimensional RF pulses, is characterized in that in a definition step, a resolution grid with resolution grid cells is predetermined, and in accordance with a predetermined phase encoding scheme, an excitation pattern is defined for each phase encoding step, in which the amplitudes within the imaging area are set in accordance with a predetermined distribution identically for each phase encoding step. In a preparatory step, the amplitude and phase behavior of the RF pulses to be irradiated is calculated in accordance with a predetermined k-space trajectory for each defined complex excitation pattern.
    Type: Grant
    Filed: September 13, 2008
    Date of Patent: December 20, 2011
    Assignee: Bruker BioSpin MRI GmbH
    Inventor: Wolfgang Ruhm
  • Patent number: 8063640
    Abstract: A method for measuring an sample in an NMR spectrometer uses a coupling configuration (1; 30) comprising a coupling element (3) and a supply capillary (2), wherein the coupling element (3) has a funnel-shaped section (5) which clamps an end (6) of the supply capillary (2). An envelope capillary (10) is provided into which the supply capillary (2) is inserted, wherein the end (6) of the supply capillary (2) projects past an end (11) of the envelope capillary (10), and the end (11) of the envelope capillary (10) is also clamped in the funnel-shaped section (5).
    Type: Grant
    Filed: September 15, 2010
    Date of Patent: November 22, 2011
    Assignee: Bruker BioSpin GmbH
    Inventors: Martin Hofmann, Thorsten Marquardsen
  • Publication number: 20110271694
    Abstract: A cryostat configuration (10), with at least one cryostat (11), which has at least one first chamber (1) with supercooled liquid helium having a temperature of less than 4 K and at least one further chamber (2), which contains liquid helium having a temperature of approximately 4.
    Type: Application
    Filed: May 4, 2011
    Publication date: November 10, 2011
    Applicant: Bruker BioSpin GmbH
    Inventors: Marco Strobel, Gerhard Roth
  • Publication number: 20110234227
    Abstract: A method for designing the time dependence function km(t) for a given k-space trajectory km, where m stands for one or multiple of the spatial dimension indices x, y, or z, of a magnetic resonance imaging (=MRI) experiment carried out on an MRI system, wherein the trajectory km is generated by applying a time varying waveform gm(t) of a gradient magnetic field, the method taking into account—the gradient magnitude limit G and—the gradient slew rate limit S of the MRI system, is characterized in that the method further takes into account a given frequency limit F in such a way that the gradient waveform gm(t) does not contain frequency components above the frequency limit F which is characteristic for the gradient hardware of the MRI system. The invention provides a method for designing a time dependence function for a given k-space trajectory, which allows obtaining better quality MRI images.
    Type: Application
    Filed: March 16, 2011
    Publication date: September 29, 2011
    Applicant: Bruker BioSpin MRI GmbH
    Inventors: Markus Weiger Senften, Thomas Oberhammer, Franciszek Hennel
  • Publication number: 20110199083
    Abstract: A method for generating magnetic resonance (MR) images or MR spectra of at least one partial area (2a) of a moving object (2) with at least one motion sequence that is repeated during consecutive motion states (BZ) is proposed. In a learning measurement, a monitor signal of the repeating motion sequence is recorded, and MR test data of the partial area (2a) of the object (2) are recorded under known measurement conditions, wherein the MR test data is associated with the motion states (BZ) of the motion sequence. In an evaluation step, the MR test data of the motion states (BZ) of the motion sequence are compared to each other with respect to at least one parameter, and the variation of the at least one parameter over the motion sequence is determined.
    Type: Application
    Filed: February 3, 2011
    Publication date: August 18, 2011
    Applicant: Bruker BioSpin MRI GmbH
    Inventor: Arno Nauerth
  • Patent number: 7999545
    Abstract: A method for determining amplitude and phase dependencies of radio frequency pulses that are irradiated during traversal of a defined k-space trajectory to produce a spatial pattern of the transverse magnetization in an MR experiment using at least one RF transmission antenna, is characterized in that, in a calibration step, a set of basic pulses is defined, each basic pulse is irradiated individually, the specified k-space trajectory is traversed and at least one set of basic patterns is produced by detection of the MR signals thus excited, which in a range to be examined of the object, are proportional to the complex transverse magnetization produced, wherein the k-space trajectory is traversed fully identically every time at least from the beginning of the irradiation of each basic pulse, and, in a calculation step, a defined target pattern is approximated with a linear combination of the basic patterns of a set or with a mathematical association of linear combinations, with which, within each set, the bas
    Type: Grant
    Filed: December 5, 2007
    Date of Patent: August 16, 2011
    Assignees: Bruker BioSpin MRI GmbH, Universitaetsklinikum Freiburg
    Inventor: Peter Ullmann
  • Publication number: 20110175611
    Abstract: A method for sample preparation for magnetic resonance measurements using Hyperpolarization by Dissolution Dynamic Nuclear Polarization, involves preparation of frozen beads of a first kind containing paramagnetic substances in addition to the solute under investigation; insertion of the frozen beads into a polarizing magnet; creation of enhanced polarization of nuclei in a magnetic field; heating of the sample to room temperature; transfer of the sample to an MR magnet; and carrying out an MR measurement. In addition, frozen beads of a second kind containing a reducing agent are prepared and inserted into the polarization magnet together with the frozen beads of the first kind. By this method, longitudinal and transverse relaxation times in NMR are extended and free radicals in hyperpolarized solutions are eliminated.
    Type: Application
    Filed: January 12, 2011
    Publication date: July 21, 2011
    Applicants: Bruker BioSpin AG, Ecole Polytechnique Federale de Lausanne (EPFL)
    Inventors: Sami Jannin, Pascal Mieville, Geoffrey Bodenhausen
  • Patent number: 7982566
    Abstract: A cryostat (1) with a magnet coil system including superconductors for the production of a magnet field B0 in a measuring volume (3) within a room temperature bore (2) of the cryostat has a plurality of radially nested solenoid-shaped coil sections (4, 5, 6) which surround the room temperature bore and which are electrically connected in series, at least one of which being an LTS section (5, 6) with a conventional low temperature superconductor (LTS) and at least one of which being an HTS section (4) including a high temperature superconductor (HTS), wherein the LTS section (5, 6) is located in a helium tank (9) of the cryostat (1) along with liquid helium at a helium temperature TL. The apparatus is characterized in that the HTS section (4) is disposed radially within the LTS section (5, 6) in a vacuum portion of the cryostat and is separated from the LTS section (5, 6) by the helium tank (9) wall (9a) facing the room temperature bore.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: July 19, 2011
    Assignee: Bruker BioSpin GmbH
    Inventor: Arne Kasten
  • Publication number: 20110133734
    Abstract: A method for regulating radio frequency (RF) signals in a nuclear magnetic resonance (NMR) system, comprising a spectrometer, a control loop, and an NMR probe head with RF components (BE, LE, BK), wherein the spectrometer comprises a transmitter that transmits RF signals at measuring frequencies with a transmission power (PS), the NMR probe head contains an RF oscillating circuit, and the RF oscillating circuit comprises an RF coil (LE), is characterized in that the control loop controls the duration and/or the phase and/or the power of the transmitted RF signals. Measurement of a parameter is performed by means of the NMR probe head, via which parameter the current in or the voltage across one of the RF components (BE, LE, BK) can be determined, and the transmission powers (PS) and/or the phases and/or the duration of the RF signals are regulated in dependence on the measured parameter. Any occurring losses can thereby be compensated for without reducing the pulse duration.
    Type: Application
    Filed: December 6, 2010
    Publication date: June 9, 2011
    Applicant: Bruker BioSpin AG
    Inventor: Nicolas Freytag
  • Publication number: 20110136672
    Abstract: A hollow tube (1), for inserting superconductor precursor material such as superconductor precursor rods (13) into its bore (3), wherein the tube (1) extends along an axial direction, and wherein the tube (1) comprises a matrix (4) made of a first ductile material, is characterized in that a plurality of continuous filaments (5), extending along the axial direction of the tube (1), are distributed in the matrix (4), wherein the continuous filaments (5) are made of a second ductile material. With the invention, a good quality mechanical reinforcement of superconductor wires, in particular which can be used without later hot extrusion, can be achieved.
    Type: Application
    Filed: November 1, 2010
    Publication date: June 9, 2011
    Applicant: Bruker BioSpin AG
    Inventors: Florin Buta, René Flükiger
  • Publication number: 20110101981
    Abstract: Each NMR rotor bearing in an NMR magic angle spinning assembly is constructed of a porous ceramic material and has no inlet channels or nozzles. Instead, pressurized gas is forced through pores in the bearing ceramic material from an annular groove at the bearing periphery to the central aperture. Since the pores are small and very numerous, the gas pressure is effectively balanced around the periphery of the central aperture. In addition, if contaminants block one or more pores during operation, the pores are so numerous that the balanced pressure can still be maintained in the central aperture, thereby preventing an imbalance that could destroy the rotor.
    Type: Application
    Filed: October 29, 2009
    Publication date: May 5, 2011
    Applicant: BRUKER BIOSPIN CORPORATION
    Inventor: Eckhard Bez
  • Publication number: 20110099356
    Abstract: A device for real-time correction of set-point signals intended to receive at the input set-point signals and to deliver at its output set-point signals that are modified to compensate for defects, negative effects or the like subsequently encountered during the processing and/or the application of the set-point signals. This device (1) includes at least one circuit (1?) that is based on a microprogrammed structure and composed of several subassemblies (3, 4, 5, 6, 6?) that work with digital components essentially including a micro-sequencer (3) forming a counter, a memory (4) for storing micro-instructions, and a processing unit (5) combined with at least one working memory (6, 6?) and integrating arithmetic calculation modules (7, 7?), whereby the processing unit (5) modifies the data of set-point signals in accordance with the micro-instructions that are addressed by the micro-sequencer (3) and by taking into account the correction coefficients that are provided.
    Type: Application
    Filed: October 26, 2010
    Publication date: April 28, 2011
    Applicant: BRUKER BIOSPIN
    Inventor: Ernest SCHAEFER
  • Publication number: 20110079288
    Abstract: Apparatus for preventing energy leakage from a transmission line treats the line as a “partially closed” vessel. A gas stream with a pressure slightly different from ambient pressure is provided to the interior of the transmission line and a conduit that allows gas to pass between the transmission line and the ambient environment is provided. The gas flow rate at the conduit is then detected and monitored. If the flow rate falls outside a predetermined threshold, an electrical energy leakage is indicated. In another embodiment, the pressure of the input gas to the transmission line is continuously checked by a pressure switch, which will detect a change in pressure if the transmission integrity is compromised and disable the energy source.
    Type: Application
    Filed: October 1, 2009
    Publication date: April 7, 2011
    Applicant: BRUKER BIOSPIN CORPORATION
    Inventors: Eckhard Bez, Melanie Rosay, Leo Tometich
  • Patent number: 7919963
    Abstract: A resonator assembly for executing measurements on a sample within a constant magnetic field B0 by means of magnetic resonance is disclosed. It comprises a resonator portion defining a longitudinal axis and an axial direction. The resonator portion has, along the axial direction, a hollow cavity for exciting electron resonance within the sample. A coupling portion is provided adjacent the resonator portion and has, along the longitudinal axis, a stepped through being electrically conductive at its inner surface. A first, middle section of the stepped through configures the hollow cavity. A second and a third, lateral section adjacent axially opposed sides of the hollow cavity are each dimensioned such that a basic mode being resonant within the hollow cavity is unable to propagate within the second and the third section. A coil is wound around the resonator portion for additionally exciting a nuclear resonance within the sample.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: April 5, 2011
    Assignee: Bruker Biospin, GmbH
    Inventors: Alexander Krahn, Peter Hoefer, Marian Kloza, Frank Engelke
  • Patent number: 7898258
    Abstract: A superconducting magnet configuration (4; 14) for generating a homogeneous magnetic field B0 in an examination volume (4b), has an interior radial superconducting main field coil (1) which is disposed rotationally symmetrically about an axis (z-axis) and an oppositely driven coaxial radially exterior superconducting shielding coil (2) is characterized in that the magnet configuration (4; 14) consists of the main field coil (1), the shielding coil (2), and a ferromagnetic field formation device (3; 18), wherein the ferromagnetic field formation device (3; 18) is located at the radially inside of the main field coil (1), the main field coil (1) consisting of an unstructured solenoid coil or of several radially nested unstructured solenoid coils (15, 16) which are driven in the same direction, the axial extent Labs of the shielding coil (2) being smaller than the axial extent Lhaupt of the main field coil (1), wherein the axial magnetic field profile (5) generated by the main field coil (1) and the shielding co
    Type: Grant
    Filed: April 16, 2009
    Date of Patent: March 1, 2011
    Assignee: Bruker BioSpin GmbH
    Inventors: Gerald Neuberth, Michael Westphal
  • Patent number: 7895737
    Abstract: A winding machine (1) for winding solenoid-shaped coils (21) with band-shaped conductors (6), comprising a winding means (3) which holds a circular-cylindrical coil core (2) of a coil (21) to be wound, and a winding drive which rotates a coil core (2), which is held in the winding means (3), about a winding axis W, wherein the winding means (3) can be moved in a first direction A by an axial drive, the direction A preferably extending approximately parallel to the winding axis W, is characterized in that the winding means (3) can be rotated about a pivot axis S by a pivot drive, wherein the pivot axis S extends perpendicularly to the direction A. The winding machine winds a solenoid-shaped coil with several layers of a band-shaped conductor without damaging the band-shaped conductor, in particular, when the band-shaped conductor contains brittle superconducting material.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: March 1, 2011
    Assignee: Bruker Biospin GmbH
    Inventors: Gerhard Roth, Klaus Schlenga, Thorsten Greeb, Roland Binger
  • Patent number: 7887644
    Abstract: The invention relates to a composite (1), comprising a Cu—Sn bronze matrix (2) and filaments (3) surrounded by the bronze matrix (2), wherein the filaments (3) contain niobium (?Nb) or a Nb alloy, characterized in that the filaments (3) contain between 0.3% and 20% of volume of copper (?Cu) substructures (4), which are distributed within the Nb or the Nb alloy. The composite can be used to produce a superconducting element with the bronze route which has an improved critical current density.
    Type: Grant
    Filed: July 10, 2006
    Date of Patent: February 15, 2011
    Assignee: Bruker Biospin AG
    Inventors: René Flükiger, Daniel Eckert