Abstract: A flow control system including: a tubing clamp that includes a clamping mechanism for holding closed a first fluid line while a second fluid flows along a second fluid line from a second container; a drip chamber having a one-way check valve; a vacuum activated catch retainably coupled with the tubing clamp and coupled with the second fluid line and including a movable element coupled with the tubing clamp, the movable element changing from a first shape to a second shape upon receipt of a deforming pressure, wherein when the movable element is in the first shape, the vacuum activated catch retains the tubing clamp in a closed position, and when the movable element is in the second shape, the vacuum activated catch releases the tubing clamp into an open position; and an infusion pump that draws a vacuum in the second fluid line.