Abstract: Described is an “artificial virus” (AV) programmed with biomolecules that can enter human cells and carry out precise human genome modification. The AVs comprise: at least one viral vector, such as bacteriophage T4; at least one therapeutic molecule, such as DNA, RNA, protein and their complex; and a lipid coating. Also described is a method of human genome modification, using such an AV, and a method of program such an AV.

Abstract: The present invention relates to an exosome for stimulating T cells and the pharmaceutical use thereof. Immune exosomes secreted from artificial antigen-presenting cells which express HLA, CD32, and co-stimulatory molecules CD32, CD80, CD83, and 4-1BBL are used to stimulate naive CD8+ T cells whereby preventive and therapeutic effects on tumors, pathogen infections, or autoimmune diseases can be provided.

Abstract: The present invention relates to a method of simultaneously diagnosing active tuberculosis and latent tuberculosis infection (LTBI) using one or more biomarkers selected from a white blood cell count, a hemoglobin concentration, a neutrophil count, a lymphocyte count, a monocyte count, a procalcitonin concentration, a C-reactive protein concentration, an ?1-acid glycoprotein concentration and an erythrocyte sedimentation rate, or a combination thereof. The present invention may provide a diagnostic method for simultaneously differentiating active tuberculosis and LTBI without a separate additional test on a patient diagnosed as positive by a conventional tuberculosis infection assay such as a tuberculin skin test (TST) or an interferon-T release assay (IGRA).

Abstract: The present invention relates to a novel feeder cell and a method for growing gamma delta T cells using the same. More specifically, a large amount of gamma delta T cells may be grown in vitro with high purity and without simulation of a T cell receptor by using a feeder cell into which costimulatory molecules are introduced and a low concentration of IL-2, differentiation into central memory cells may be possible when stimulated, activity by the feeder cell, and cytolytic against tumour cells is provided.

Abstract: Described is hybrid viral vector comprising: a first virus such as bacteriophage T4; one or more second virus such as adeno-associated virus (AAV) attached to the first virus through cross-bridges, such as avidin-biotin cross-bridges; one or more DNA molecules packaged in the first virus; one or more nucleic acid molecules packaged in the second virus; and one or more proteins displayed on the surface of the first virus. Also described are methods of making and using such a hybrid viral vector.

Abstract: The present disclosure relates to a device for and a method of interfacial electrofabrication of freestanding biopolymer membranes comprising at least one anode; at least one cathode; at least one anode electrolyte; and at least one cathode electrolyte, wherein at least a portion of the at least one anode electrolyte and the at least one cathode electrolyte form an interface, wherein at least one polyelectrolyte complex membrane (PECM) forms at the interface of the at least one anode electrolyte and the at least one cathode electrolyte, wherein the at least one anode electrolyte and the at least one cathode electrolyte are separated by the PECM, wherein the at least one anode is disposed in the at least one anode electrolyte, wherein the at least one cathode is disposed in the at least one cathode electrolyte, and wherein the at least one anode and the at least one cathode are distal from the interface of the at least one anode electrolyte and the at least one cathode electrolyte.

Abstract: The present invention relates to a system and method for monitoring the safety of users in a shaded area, wherein location information about an RFID post installed in a shaded area is identified by means of an RFID tag, so that the location of a work group working in the shaded area can be transmitted to a control server in real time, and the control server compares the location of the work group with operation information about trains, thereby determining whether the work group is in danger or not, makes notification the same, so that the safety of the work group can be secured.

Abstract: A stent device including a stent coated with a photosensitizer, the stent including a pair of electrodes; and a circuit fixed to the stent, the circuit including a light emitting diode, a power receiving means for wirelessly receiving power from the outside, and converting the power to electric power; a second communicating means for receiving a control command from the outside; and a second control means for applying, based on the control command, the electric power to the electrodes causing an electric current to flow through the stent between the electrodes, the flow causing heating of the stent, and for controlling a temperature of the stent to provide hyperthermia therapy to a tumor, the second control means further for applying, based on the control command, the electric power to the light emitting diode to emit a predetermined wavelength of light to the photosensitizer to provide photodynamic therapy to the tumor.

Abstract: The present invention relates to an artificial bladder system having a double space divided by a partition wall and a wireless, non-powered urine fullness sensor using an RFID technology, which provides an artificial bladder system comprising: an outer wall that forms the outer shape of the artificial bladder, is inserted into the body, and has an inner space; a partition wall, wherein both ends are fixed to the inside of the outer wall, the inner space of the outer wall is divided into a double space of a urine reservoir and a working fluid space, and it is deformable according to amounts of the urine and the working fluid; and a urine fullness sensor installed in the working fluid space and sensing a urine fullness degree based on the deformation of the partition wall.

Abstract: A geopolymer thermal energy storage (TES) concrete product comprising at least one binder; at least one alkali activator; at least one fine aggregate with high thermal conductivity and heat capacity; and at least one coarse aggregate with high thermal conductivity and heat capacity.

Abstract: Described is an “artificial virus” (AV) programmed with biomolecules that can enter human cells and carry out precise human genome modification. The AVs comprise: at least one viral vector, such as bacteriophage T4; at least one therapeutic molecule, such as DNA, RNA, protein and their complex; and a lipid coating. Also described is a method of human genome modification, using such an AV, and a method of program such an AV.

Abstract: The present invention relates to a method of simultaneously diagnosing active tuberculosis and latent tuberculosis infection (LTBI) using one or more biomarkers selected from a white blood cell count, a hemoglobin concentration, a neutrophil count, a lymphocyte count, a monocyte count, a procalcitonin concentration, a C-reactive protein concentration, an ?1-acid glycoprotein concentration and an erythrocyte sedimentation rate, or a combination thereof. The present invention may provide a diagnostic method for simultaneously differentiating active tuberculosis and LTBI without a separate additional test on a patient diagnosed as positive by a conventional tuberculosis infection assay such as a tuberculin skin test (TST) or an interferon-? release assay (IGRA).

Abstract: Bivalent immunogenic compositions against anthrax and plague are disclosed herein. One bivalent immunogenic composition comprises a triple fusion protein containing three antigens, F1 and V from Yersinia pestis and PA antigen from Bacillus anthracis fused in-frame and retaining structural and functional integrity of all three antigens. Another bivalent immunogenic composition comprises bacteriophage nanoparticles arrayed with these three antigens on the capsid surface of the bacteriophage nanoparticles. These bivalent immunogenic compositions are able to elicit robust immune response in a subject administered said the bivalent immunogenic compositions and provide protection to the subject against sequential or simultaneous challenge with both anthrax and plague pathogens.

Abstract: Described is hybrid viral vector comprising: a first virus such as bacteriophage T4; one or more second virus such as adeno-associated virus (AAV) attached to the first virus through cross-bridges, such as avidin-biotin cross-bridges; one or more DNA molecules packaged in the first virus; one or more nucleic acid molecules packaged in the second virus; and one or more proteins displayed on the surface of the first virus. Also described are methods of making and using such a hybrid viral vector.

Abstract: The present invention relates to a urine test container, Specifically, the present invention relates to a container capable of readily separating first urine while receiving whole urine in order to remove the inconvenience of discarding the first urine and putting the remaining urine in a container in a medical institution such as a hospital and a health care institution, because the quality of a test is decreased due to a plurality of epithelial cells included in the first urine in a urine test.

Abstract: A system to align an object using a light reflector, including: an input unit for pre-setting a first region in which radiation is to be emitted to the object; a display unit for displaying information on the first region; a radiation unit for emitting radiation to the first region; a reflector formed to correspond to the shape of the first region and configured to be attached to the first region; a light unit for emitting light in the same direction as the radiation to the first region; a camera for photographing a region of the reflector when the reflector reflects light emitted by the light unit; and a control unit for controlling the display unit to display the region of the light reflector which reflects light photographed by the camera, and determining whether the radiation is aligned to the first region of the object based on whether the region of the light reflector is included in the shape of the first region.

Abstract: An embodiment includes a Class C fly ash (CFA) cementitious composition with a controllable setting time comprising at least one Class C fly ash; at least one alkali hydroxide; at least one source of phosphate; and water. Alternate embodiments include a Class C fly ash (CFA) cementitious composition with a solid activator comprising at least one Class C fly ash; at least one alkali carbonate; at least one source of phosphate; and water.

Abstract: The present disclosure relates to a calculus removing device which is used in the medical field. More particular, the present disclosure relates to a calculus removing device which has a lithotripsy probe capable of simultaneously destructing and removing the calculus formed in the human body regardless of the size of the calculus by optionally using attractivity or electricity through a lithotripsy probe.

Abstract: The present invention relates to a thermoplastic mask monitoring system using a pressure sensor. Specifically, a thermoplastic mask according to the present invention may include: a mask having a shape determined according to a shape of a first region which is at least a part of a patient's body by using thermoplasticity, fixing the first region in close contact with the first region, and receiving radiation; and a pressure sensor provided between the mask and the first region and sensing pressure induced by a space generated between the mask and the first region.

Abstract: Disclosed herein is a snare (transparent cap) for removing a polyp which includes a stalk and a head connected to the stalk, wherein the snare includes: a body having a hollow tubular shape and an interior of which is partitioned into a plurality of chambers; a ring mounted to at least part of the body using elasticity; a first snare discharged outside the body through a first chamber among the plurality of chambers and hooks the stalk; and a second snare which is discharged outside the body through a second chamber among the plurality of chambers, wherein when the stalk is spread according to pulling the first snare that hooks the stalk, and the second snare pulls a first portion in a lower end of the stalk as spread including the head, the ring is discharged from the body and shrinks through the elasticity and then fixes the first portion.