Abstract: There is provided a method for determining dementia risk factors by a server using deep learning. In this instance, the method for determining dementia risk factors includes acquiring biometric information from each subject corresponding to a first control group through a wearable device, acquiring measurement information for each subject corresponding to the first control group, deriving a first dementia risk factor based on the biometric information and the measurement information for each subject, and deriving a second dementia risk factor related to the first dementia risk factor via deep learning performed based on the biometric information related to the first dementia risk factor and control group information.

Abstract: A bone tumor surgery device according to an embodiment of the present invention comprises: an accommodation container in which an accommodation space for accommodating a bone of a patient is formed; and a radiofrequency supply unit for supplying radiofrequency into the accommodation space.

Abstract: The present invention relates to a system and method for monitoring the safety of users in a shaded area, wherein location information about an RFID post installed in a shaded area is identified by means of an RFID tag, so that the location of a work group working in the shaded area can be transmitted to a control server in real time, and the control server compares the location of the work group with operation information about trains, thereby determining whether the work group is in danger or not, makes notification the same, so that the safety of the work group can be secured.

Abstract: The present invention relates to a composition which is for preventing or treating bone diseases and includes CCR2 as an active ingredient. It was confirmed that a C—C chemokine receptor type 2 (CCR2) protein, a polynucleotide encoding the CCR2 protein, or a mesenchymal stem cell transduced with the CCR2 according to the present invention neutralize bone disease factor MCP-1, thereby reducing the collagen epitope (CTX-II) and collagen metabolism factors (MMP1 and MMP3) relating to collagen absorption in the body. In addition, it was confirmed that the expression of the SOX9 gene and anti-inflammatory cytokines (TGF-? and IL-10) related to cartilage differentiation was significantly increased. Thus, the present invention has excellent regenerative ability against osteoarthritis and excellent pain suppression and alleviation effects, and thus can be effectively used for preventing or treating bone diseases such as osteoarthritis.

Abstract: A geopolymer thermal energy storage (TES) concrete product comprising at least one binder; at least one alkali activator; at least one fine aggregate with high thermal conductivity and heat capacity; and at least one coarse aggregate with high thermal conductivity and heat capacity.

Abstract: A multilayer cornea harvesting apparatus capable of obtaining layers of cornea from one cornea enucleation object and a cornea harvesting method is disclosed. The apparatus includes a base supported on a bottom surface, a mount detachably coupled to the base, allowing a cornea enucleation object to be placed thereon, having a first opening part formed at a portion corresponding to the cornea of the cornea enucleation object, and having a first medicinal fluid charging space formed between the base and the mount, a stabilizer fixing, to the mount, a sclera portion of the cornea enucleation object placed on the mount and having a second opening part formed at a portion corresponding to the cornea, and an upper cover detachably provided on the upper side of the cornea, supported by the mount or supporting the mount, and forming a second medicinal fluid charging space on the upper side of the cornea.

Abstract: Provided is an artificial bladder including: a main body which includes an inlet port, an outlet port, and a predetermined reservoir portion configured to store urine between the inlet port and the outlet port and is formed of a biocompatible polymer that is expandable so that a volume of the reservoir portion changes according to the amount of urine; a sensor which is attached to an outer wall of the main body, has a surface having a wrinkled structure, and is provided so that, when the volume of the reservoir portion increases, the wrinkled structure stretches out and resistance of the sensor changes; and an actuator which is provided at the outlet port and is configured to discharge the urine according a result detected by the sensor.

Abstract: A hemostatic device is disclosed. The hemostatic device according to an embodiment of the present invention includes: a balloon which is expanded by a fluid supplied therein; a blood discharge pipe which includes a blood inflow hole at one end and exposes the other end to a lower side of the balloon wherein a certain section of a lower side of the blood inflow hole is surrounded by the balloon; and a fluid flow pipe communicating with the inside of the balloon for supplying or discharging the fluid and extending to a lower side of the balloon. The balloon includes a plurality of protrusions that are formed to protrude outward when the balloon is expanded by the fluid.

Abstract: The present invention relates to an extensible drug injection device capable of injecting a drug from a location away from a patient, and an operation method therefor. Disclosed is a drug injection device comprising: a first sub-line of which one end joins with a main line, connected from a first drug storage part for storing a first drug to be injected into a patient to the body of the patient such that the first drug flows therein, and of which the other end is extended to the other side; a second drug injection part which is connected to the first sub-line and which injects a second drug that is different from the first drug; and a second drug pumping part which is connected to the first sub-line, and which pushes, to the main line, the second drug having been injected by the second drug injection part into the first sub-line.

Abstract: The present invention provides a human-computer interactive rehabilitation system, which can automatically calculate rehabilitation strength suitable for the patient, so that it is not necessary to manually evaluate and adjust the parameter settings in human-computer interactive rehabilitation system when different patients use it. At the same time, the human-machine interactive rehabilitation system and the hospital end can track the rehabilitation status and intervene through the data platform at any time. The platform establishes a cloud community feedback and encouragement mechanism, and immediately transmits the rehabilitation results to the designated barriers of the patients, provides patient encouragement feedback, and strengthens the community interaction and linkage in the medical relationship.

Abstract: The present invention relates to: a biomarker composition for diagnosing or predicting the prognosis of thyroid cancer, comprising a preparation capable of detecting a mutation in a PLEKHS1 promoter gene; and a use thereof. The biomarker composition for diagnosing or predicting the prognosis of thyroid cancer of the present invention confirms whether a mutation is present in a PLEKHS1 promoter gene, and thus can provide information needed for diagnosing metastatic (distant metastatic) differentiated thyroid cancer, and also confirms whether a mutation is present in BRAF, TERT promoter, three types of RAS and a TP53 gene in addition to the PLEKHS1 promoter gene, and thus, with respect to radioactive iodine therapy response and survival, can classify the prognosis of a metastatic differentiated thyroid cancer patient into one of three prognosis groups, and predict the same.

Abstract: Provided is a method for preventing or treating a retinal degenerative disease, comprising administering to a subject in need thereof human neural crest-derived nasal inferior turbinate stem cells as an active ingredient, in which the stem cells are differentiated into rod photoreceptor cells among photoreceptor cells expressing rhodopsin and prevent or treat a retinal degenerative disease including age-related macular degeneration.

Abstract: Provided is a medical test slide unit including a frame main body including: a marker part which has a thin plate shape and in which a plurality of position indicating markers are formed longitudinally and transversely; and a border part arranged to surround the marker part, wherein a step is formed between the border part and the marker part to form a seating recess, and wherein a slide, on which a specimen to be examined using a microscope is placed, is selectively seated in the seating recess.

Abstract: The present invention relates to an apparatus for patient-controlled drug injection having a counter capable of counting the number of administrations. According to one aspect of the present invention, disclosed is an apparatus for patient-controlled drug injection having a counter, comprising: a case; a pressing part, provided in the case, for applying pressure to pump a chemical liquid; and a counter, provided in the case and having a counting button that is pressed by pressure when a user presses the pressing part, for counting the number of times that the pressing part is pressed.

Abstract: The present invention relates to: a recombinant peptide in which a Mitochondria Localization Sequence (MLS) peptide and the Signal Transducer and Activator of Transcription 3 (STAT3) are fused to each other; a recombinant vector carrying a polynucleotide coding for the recombinant peptide; and a composition comprising the recombinant peptide or the recombinant vector as an active ingredient for prevention or treatment of autoimmune disease or inflammatory disease, wherein the recombinant peptide or the recombinant vector allows STAT3 to be overexpressed in the mitochondria to enhance the mitochondrial function, resulting in inhibiting the expression of inflammatory cytokines including IL-17, whereby the composition may be advantageously used for preventing or treating autoimmune disease or inflammatory diseases.

Abstract: Described is an “artificial virus” (AV) programmed with biomolecules that can enter human cells and carry out precise human genome modification. The AVs comprise: at least one viral vector, such as bacteriophage T4; at least one therapeutic molecule, such as DNA, RNA, protein and their complex; and a lipid coating. Also described is a method of human genome modification, using such an AV, and a method of program such an AV.

Abstract: The present disclosure relates to a pharmaceutical composition comprising a nucleic acid molecule of an adjuvant, a metal complex stabilizing the nucleic acid molecule, and optionally an immunogen that may be a peptide or a protein, or a composition of stabilizing the nucleic acid molecule of the adjuvant comprising the metal complex. The metal complex interacts with the nucleic acid molecule of the adjuvant and/or the immunogen so as to stabilize such pharmaceutically active ingredients, and induces continuous effectiveness of the active ingredients without degradation.

Abstract: The present invention relates to markers for diagnosing the difference in effects of renal cancer treatment or the prognosis of renal cancer patients, according to the gender of renal cancer patients. The survival rate and recurrence rate of renal cancer of a particular gender respectively relate to the mutation of genes, of the present invention, in renal cancer patients, and thus the mutated genes of the present invention can be used as markers in predicting, on the basis of gender, the difference in effects of renal cancer treatment or the prognosis of renal cancer patients.

Abstract: The present invention relates to a bellows framework having a concave-convex structure on at least one of outer and inner sides using three-dimensional printing technology and a method of producing thereof, and an artificial tracheal replacement comprising an epithelium part formed on the inner side of the bellows framework and an annular cartilage part formed along the circumference of concave-convex grooves on the outer side and a method of producing thereof.

Abstract: A method for analyzing the methylation level of a specific CpG site in genomic DNA and a composition suitable to use in the method are provided. The method and composition can provide information useful for diagnosing thyroid cancer or determining the prognosis of patients with thyroid cancer. By using the method and the composition, thyroid cancer can be easily and accurately diagnosed from biological samples at a low cost.