Abstract: The systems and methods disclosed herein provide multiple solutions from maximizing efficiencies for propulsion and electrical plant equipment to reducing life cycle costs. Knowing how equipment is used/operated and how fuel is used to power equipment can increase awareness and can help to provide the best opportunity to maximize the technological gains in power generation. The systems and methods disclosed herein can provide such awareness by displaying current and projected fuel consumption attributable to specific factors encountered in operational conditions, including the environment, hull fouling, displacement and engineering plant modes. Systems and methods employ physics and quantitative based methodology that focus on assessing and quantifying fuel utilization impacts due to machinery employment, material condition disparities, abnormal configurations and excess usage.

Abstract: Proximity coupling and sequencing methods to screen, identify, validate and/or characterize interactions between analytes and binding moieties are disclosed. Also disclosed herein are proximity coupling methods and sequencing methods to determine or quantify levels of target analytes. The disclosed methods can be multiplexed in two dimensions, and can be used to determine the affinity and specificity of each of a plurality of binding moieties for each of a plurality of target analytes. Also disclosed herein are substrates, arrays, and reagents for use in the methods, and methods of their preparation.

Abstract: A flowmeter of the thermal type, having a heated flow-sensing element and a temperature-sensing reference element, the elements constructed and arranged to be installed in a pressurized pipe. The flowmeter has one probe with the heated element and a separate second probe with the reference element. The probes are constructed and arranged to pass through the pipe wall in separate through-holes. There is a mounting structure such as a split ring that is adapted to be mounted to the pipe. Two valves operatively coupled to separate locations of the mounting structure, where one probe passes through each valve and into the pipe.

Abstract: An expandable downhole sealing assembly in which an axial setting force is applied to radially compress and self-energize an expanding element such that stored radial forces in the expanding element effect and maintain a seal thereafter. The sealing assembly can be used to provide a seal between a casing and a mandrel in a well, among other applications.

Abstract: A sealing assembly for sealing an annulus in a downhole application including a sealing ring and a deflecting ring axially aligned between axially opposed mesh back-ups, each of the sealing ring and the deflecting ring defining a first ramped end, the first ramped ends facing each other such that an axial set force applied to the deflecting ring deflects the sealing ring radially outward forcing the sealing ring into a side-by-side arrangement with the deflecting ring to fill and seal the annulus.

Abstract: A flowmeter of the thermal type, having a heated flow-sensing element and a temperature-sensing reference element, the elements constructed and arranged to be installed in a pressurized pipe. The flowmeter has one probe with the heated element and a separate second probe with the reference element. The probes are constructed and arranged to pass through the pipe wall in separate through-holes. There is a mounting structure such as a split ring that is adapted to be mounted to the pipe. Two valves operatively coupled to separate locations of the mounting structure, where one probe passes through each valve and into the pipe.

Abstract: Disclosed herein are compositions and methods for increasing protein production from a cell culture. By switching the cells from a replicative to a productive state (RP switch), protein biosynthesis is extended. The productive state is a pseudo-senescent state. This pseudo-senescent state can be induced by transforming the cells with a vector expressing a cell cycle inhibitor. Expression of the cell cycle inhibitor within the cell, because it does not cause cell death, allows for cells to be maintained in culture for longer periods. The invention allows for controlled enhanced protein biosynthetic productivity of cell lines for commercial and research purposes.

Abstract: Disclosed herein is a method and system for leading composition capable of being performed by the leading of an instructor with respect to the composition prepared and submitted by a learner, in which errors are extracted from the composition, so that teaching and learning composition are performed through correction, error remediation, and index study based on the errors. The method for teaching and learning composition comprises constructing a learning composition database including an index database wherein index information associated with the composition is stored, providing a learning topic to a learner with reference to the leading composition database and receiving correction information associated with the composition prepared by the learner from an instructor, extracting the index information from the index database included in the leading composition database; and providing instruction information including the correction information and the index information to the learner.

Abstract: A flowmeter which clamps around and seals to a pipe with probes projecting into the pipe through holes in the pipe, the useful separation of the probes being achieved by their entering the pipe through separate holes.

Abstract: An interlocking system, apparatus and methods for connecting floating structures by utilizing a male-female interlocking arrangement of shafts, cams, and connector bodies which manually lock and unlock thereby permitting, when attached to structures, quick and easy connecting and disconnecting of the structures in various states of motion including rough seas.

Abstract: A low friction, dry lubricant impregnated anti-extrusion apparatus for engagement with an annular seal or packer, wherein said packer is used to seal the annular space of a well or pipe bore. The low friction, dry lubricant impregnated anti-extrusion apparatus being designed to generally avoid absorption of the compression setting forces, wherein the compression setting forces are in turn substantially transmitted through the anti-extrusion apparatus to the packer to effect radial expansion of the packer to seal the annular space, while generally preventing the extrusion of the packer at high pressures and avoiding high frictional contact between the anti-extrusion apparatus and an inner surface of the well or pipe bore.

Abstract: A bulge control compression packer having an elastomeric tubular body and a bulge control member to reinforce the tubular body. The bulge control member including interwoven support elements which generally avoid cutting and gouging the tubular body when the tubular body is in a compressed state and further, generally avoid the accumulation of slack about the bulge control member.

Abstract: The electric circuit of the torque indicator in a torque wrench is automatically adjusted by the electric circuit of a detachable adjusting and calibrating instrument which is separably connectable to the wrench so that its torsion bar is deformable by the torque applicator wrench. Each circuit includes a microprocessor with means for displaying the measured torque, and interfaces are provided to separably connect the microprocessors to each other preparatory to an adjusting or calibrating operation. Each circuit further comprises one or more bridge circuits with strain gages, amplifiers for signals at the outputs of the bridge circuits, and analog-digital converters for transmission of signals from amplifiers to the respective microprocessor.

Abstract: A system and method for providing surface detail to computer generated two-dimensional graphic images of apparel or other free-form surfaces such that the three-dimensional appearance of the image is provided or enhanced. That is accomplished through a combination of user-controlled mesh generation for providing the topology of the image "surface" and a texture-mapping technique for applying the surface detail once the mesh has been generated. The system and method of the present invention may be used as one function of a larger two-dimensional computer aided design system for apparel, footwear, textiles, interior design, or other applications where the user may wish to add surface detail to a two-dimensional computer image of a three-dimensional object or surface.