Patents Assigned to Centre National de la Recherche and Scientifique
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Patent number: 12242112Abstract: An electro-optical conversion system including an opto-mechanical conversion device which includes a ring cavity formed by an optical waveguide which extends along an annular closed curve, a micromechanical resonator that comprises at least one microbeam, and a zipper type element integrated into the ring cavity, the zipper type element including a first arm made on a portion of the ring waveguide and a second arm made on the microbeam. The conversion system also includes a capacitor with first and second electrodes separated by a gap which varies when the microbeam oscillates.Type: GrantFiled: April 19, 2022Date of Patent: March 4, 2025Assignees: COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE PARISInventors: Sébastien Hentz, Ivan Favero, Guillaume Jourdan, Julien Renard, Nicolas Roch
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Patent number: 12242184Abstract: The present invention pertains to the field of nanoimprint lithography (NIL) processes and more specifically to a soft NIL process used for providing a sol-gel patterned layer on a substrate. Specifically, this process comprises a step of adjusting the solvent uptake of the sol-gel film to 10 to 50% vol., preferably between 15 and 40% vol., by varying the relative pressure of the solvent while a soft mould is applied onto the substrate coated with the sol-gel film.Type: GrantFiled: March 8, 2018Date of Patent: March 4, 2025Assignees: UNIVERSITE D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE, UNIVERSITE PARIS-SACLAYInventors: David Grosso, Marco Faustini, Olivier Dalstein, Andréa Cattoni, Thomas Bottein
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Patent number: 12239771Abstract: Microfluidic gas exchange devices may include one or more exchange modules (100), wherein each exchange module includes: a first layer comprising: one or more primary inlets (108); a first capillary network connected to the one or more primary inlets, wherein the first capillary network extends radially outward from at least one of the one or more primary inlets, and wherein the first capillary network includes one or more injection branches (104) and a series of microchannels (106); and one or more primary outlets connected to the first capillary network; and a second layer that includes a semipermeable membrane.Type: GrantFiled: October 25, 2019Date of Patent: March 4, 2025Assignees: Centre National de la Recherche ScientifiqueInventors: Anne-Marie Haghiri, Lyas Djeghlaf, Julie Lachaux, Alisier Paris, Gilgueng Hwang
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Patent number: 12241151Abstract: The invention concerns a method for manufacturing an aircraft part, the part comprising a monocrystalline nickel-based superalloy substrate, the method consecutively implementing the steps of moulding the part at a moulding temperature greater than the melting temperature of the superalloy, and cooling the part, such that the monocrystalline superalloy has a ? phase and a ? phase, solution heat treatment of the part at a first temperature between the solves temperature of the ?? phase and the melting temperature of the superalloy, homogenising the crystalline structure or the part, cooling the part to ambient temperature, first tempering and second tempering.Type: GrantFiled: June 26, 2020Date of Patent: March 4, 2025Assignees: SAFRAN AIRCRAFT ENGINES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NATIONALE SUPERIEURE DE MECANIQUE ET D'AEROTECHNIQUE DE POITIERS, UNIVERSITE DE POITIERSInventors: Satoshi Utada, Joël Delautre, Sarah Hamadi, Jonathan Cormier, Patrick Villechaise, Jérémy Rame
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Publication number: 20250066411Abstract: The present invention relates to new glycomimetic molecules which selectively bind to the L-SIGN receptor, finding application in the medical field and, in particular, in the prevention and treatment of viral infections, in the immunotherapy of liver tumors and in the treatment of immune diseases.Type: ApplicationFiled: October 24, 2024Publication date: February 27, 2025Applicants: UNIVERSITA’ DEGLI STUDI DI MILANO, UNIVERSITÉ GRENOBLE ALPES, COMMISSARIAT A L’ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Anna BERNARDI, Sara POLLASTRI, Clara DELAUNAY, Michel THÉPAUT, Franck FIESCHI, Gianluca CAVAZZOLI
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Publication number: 20250067597Abstract: The invention is a method for processing a calibration spectrum acquired by a spectrometric detector of X or gamma photons. The method comprises a taking into account of a parametric form of a calibration function, the calibration function linking the rank of an energy channel to an energy value. The method comprises a confrontation between the channels of the peaks of the calibration spectrum and emission energies of calibration isotopes. The confrontation makes it possible to define the values of the parameters of the calibration function.Type: ApplicationFiled: December 29, 2022Publication date: February 27, 2025Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRALESUPELEC, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS-SACLAYInventors: Kélian THIS, Adrien FRIGERIO, Sébastien COLAS, Laurent LE BRUSQUET
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Publication number: 20250069633Abstract: A magneto resistive memory device including a memory array with at least one bit line (BL) and at least one source line (SL, SLB), the bit line (BL) and the at least one source line (SL, SLB) associated with a plurality of memory cells each presenting a magnetic tunnel junction and each presenting at least one selection transistor (RT) to selectively connect the bit line (BL). The memory array also includes a peripheral block configured to apply a first voltage (Vread) greater than ground voltage (Vss) on the bit line (BL) and applying a second voltage (VSL) greater than the first voltage (Vread) on the at least one source line (SL, SLB). The state stored in the selected cell is detected by using a sense amplifier (SA) of the peripheral block associated with the at least one bit line (BL) to sense the current flowing in the bit line (BL).Type: ApplicationFiled: December 28, 2022Publication date: February 27, 2025Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Victorien BRECTE, Julien LOUCHE, Fabien LEROY
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Publication number: 20250065296Abstract: A method for manufacturing a porous monolith includes: forming a sol including a sol-gel precursor in aqueous solution; at least partially filling with previously formed sol an enclosure and at least one mould contained in the enclosure, the mould including at least one opening into the sol after filling; forming a sol-gel matrix in the enclosure from the sol; removing the mould with the sol-gel matrix contained in the mould from the enclosure; and forming a porous monolith from the sol-gel matrix contained in the mould, wherein the formation of the sol, the sol-gel matrix, and the porous monolith is performed by a sol-gel process.Type: ApplicationFiled: December 22, 2022Publication date: February 27, 2025Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Laurent MUGHERLI, Marc MALEVAL, Maartine MAYNE
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Patent number: 12232883Abstract: The method of modulating epileptogenicity in a brain of an epileptic patient includes: providing a virtual brain; providing a model of an epileptogenic and of a propagation zones and loading the models in the virtual brain to create a virtual epileptic brain; acquiring data of the brain of the epileptic patient; identifying, in the data, a location of at least one possible epileptogenic zone; fitting the virtual epileptic brain against the data acquired from the epileptic patient and parametrizing the at least one possible epileptogenic zone in the virtual epileptic brain as an epileptogenic zone; and simulating, within the virtual epileptic brain, the effect of a network modulation mimicking a clinical intervention of the brain of the patient.Type: GrantFiled: October 25, 2021Date of Patent: February 25, 2025Assignees: UNIVERSITE D'AIX MARSEILLE (AMU), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ASSISTANCE PUBLIQUE—HOPITAUX DE MARSEILLE (AP-HM), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)Inventors: Viktor Jirsa, Christophe Bernard, Fabrice Bartolomei, Maxime Guye
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Patent number: 12235153Abstract: A system for controlling the activation/deactivation of an electromagnetic shielding screen of a porthole or a protective window of an optoelectronic equipment, which includes, a radiofrequency electromagnetic sensor, with a bandwidth adapted to a cut-off band of said shielding screen corresponding to a range of electromagnetic fields to be blocked, connected to a detector-rectifier with a sensitivity higher than a minimum value of the power of an electromagnetic field to be blocked by means of said shielding screen and a device for activating/deactivating said electromagnetic shielding screen, said detector-rectifier being configured, in the presence of the electromagnetic field with a power exceeding said minimum value, to activate said device for activating/deactivating the electromagnetic shielding screen by capturing the electromagnetic energy supplied by said electromagnetic fields with a power exceeding said minimum value.Type: GrantFiled: February 16, 2022Date of Patent: February 25, 2025Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES, SAFRAN ELECTRONICS & DEFENSEInventors: Quentin Tricas, Patrice Foutrel, Philippe Besnier, Xavier Castel, Claire Le Paven
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Publication number: 20250061585Abstract: The invention relates to a method for real-time tracking of the placement of a camera with respect to a 3D model comprising a keyframe base comprising a first thread of execution making it possible to estimate the current placement of the camera from a selected keyframe, characterized in that the method further comprises a step of analyzing the quality of the estimation of the placement of the camera from the image stored in a buffer memory, and a step of analyzing the sharpness of the image stored in the buffer memory from data representative of the movement of the camera, and if the quality of the estimation of the placement of the camera from the stored image and the sharpness of the stored image conform to predetermined criteria, a step of adding the image stored in the buffer memory to the keyframe base as a new keyframe.Type: ApplicationFiled: December 14, 2022Publication date: February 20, 2025Applicants: SURGAR, UNIVERSITÉ CLERMONT AUVERGNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CLERMONT AUVERGNE INPInventors: Adrien BARTOLI, Kilian CHANDELON
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Publication number: 20250062342Abstract: A method for delithiating a lithium and transition metal nitride. The method involves mixing an oxidising agent with the lithium and transition metal nitride and recovering the material obtained. The transition metal may be Mn, Fe, Co, Ni, Cu, or a mixture thereof. The material obtained by the method may be used as a negative electrode material for a lithium-ion battery.Type: ApplicationFiled: December 23, 2022Publication date: February 20, 2025Applicants: AMPERE S.A.S., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS EST CRETEIL VAL DE MARNEInventors: Nicolas EMERY, Olivier NGUYEN, Jean-Pierre PEREIRA-RAMOS, Yanlong ZHOU
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Patent number: 12227767Abstract: The present invention is in the field of oncology, and more particularly of cancer stem cells. It relates to a method for producing cancer stem cells based on overexpression of ?133p53? isoform, ?133p53? isoform, or both ?133p53? and ?133p53? isoforms; a method for predicting the risk that treatment with a chemotherapeutic anti-cancer agent induces cancer stem cells in a subject suffering from cancer from a cancer sample of said subject, based on detection of an increase in ?133p53? isoform, ?133p53? isoform, or both ?133p53? and ?133p53? isoforms following chemotherapeutic anti-cancer treatment; to therapeutic uses of a combination of chemotherapeutic anti-cancer agent and an agent reducing ?133p53? isoform, ?133p53? isoform, or both ?133p53? and ?133p53? isoforms expression; and also to screening methods for anti-cancer stem cells agents.Type: GrantFiled: February 3, 2021Date of Patent: February 18, 2025Assignees: Centre National de la Recherche Scientifique (CNRS), Universite de MontpellierInventors: Pierre Roux, Nikola Arsic, Gilles Gadea, Philippe Fort, Fanny Tomas, Véronique Gire
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Patent number: 12230240Abstract: A method and a device for controlling the propagation of acoustic waves in the vicinity of a wall, the method and device implementing a master device for controlling a set Nc of cells primarily made up of a speaker, a set of Nm microphones connected to the speaker, and a control unit, by means of control laws that determine the intensity of the electrical signal that must be sent to each speaker so as to obtain a target determined generalized acoustic impedance for each speaker, such that a fraction of the acoustic waves is absorbed by the membrane of each speaker.Type: GrantFiled: December 11, 2020Date of Patent: February 18, 2025Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NATIONALE SUPERIEURE DE MECANIQUE ET DES MICROTECHNIQUES (ENSMM), UNIVERSITE DE FRANCHE-COMTEInventors: Morvan Ouisse, Manuel Collet, Gaël Matten
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Patent number: 12227550Abstract: The present invention relates to a modified cytokine of the TNF superfamily, with reduced activity to its receptor, wherein said modified cytokine is specifically delivered to target cells. Preferably, said modified cytokine is a single chain variant of the TNF superfamily, even more preferably, one or more of the chains can-y one or more mutations, resulting in a low affinity to the receptor, wherein said mutant cytokine is specifically delivered to target cells. The targeting is realized by fusion of the modified cytokine of the TNF superfamily to a targeting moiety, preferably an antibody or antibody-like molecule. The invention relates further to the use of such targeted modified cytokine of the TNF superfamily to treat diseases.Type: GrantFiled: June 23, 2022Date of Patent: February 18, 2025Assignees: VIB VZW, UNIVERSITEIT GENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE MONTPELLIER, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE MONTPELLIERInventors: Jan Tavernier, Jennyfer Bultinck, Frank Peelman, Gilles Uze
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Patent number: 12227612Abstract: The present invention relates to compositions (self-thermally) curable on demand under the triggering action of UV-visible to near-infrared irradiation of moderate intensity, method of using same for accelerated photopolyaddition of cyclic ether-amine resins or ultrafast dark curing of cyclic ether-amine resins, and articles obtained by such method. The invention also relates to a resin casting, film or coated substrate, and an adhesive layeror bonding agent, comprising acyclic ether-amine resin obtained by an accelerated curing process according to the invention. The invention additionally relates to the use of a composition of the invention for increasing the delamination strength of laminated composite materials.Type: GrantFiled: September 25, 2019Date of Patent: February 18, 2025Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE HAUTE-ALSACEInventors: Patxi Garra, Jacques Lalevée, Fabrice Morlet-Savary, Céline Dietlin, Aurore Caron
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Patent number: 12228122Abstract: The invention relates to a system and an implementation method for pumping a fluid, the system comprising: a pump comprising a flexible membrane which has two opposing surfaces, the membrane comprising a spatially rotating permanent magnetization structure, a rigid support means to which at least a portion of the lower surface of the membrane is attached, a source of a magnetic field which is capable of generating a magnetic drive field at the location of the membrane, the magnetic drive field having a substantially homogeneous orientation.Type: GrantFiled: September 10, 2020Date of Patent: February 18, 2025Assignees: Institut Polytechnique de Grenoble, Centre National de la Recherche Scientifique, Université Grenoble AlpesInventors: Victor Vieille, Thibaut Devillers
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Patent number: 12228340Abstract: A cold crucible usable in the field of high-temperature production of monocrystalline materials. The cold crucible includes: a cold cage which has sectors made of a material having good electrical conductivity and in which a charge is melted, and a cooling device with heat transfer fluid, configured to cool each segment of the cold cage from the inside. The cold crucible is essentially such that it further includes at least one device for generating a static magnetic field, each generating device being housed inside one of the sectors of the cold crucible. Each static magnetic field thus generated having the effect of slowing down the electromagnetic stirring of the molten charge, such that it is possible to produce monocrystalline ingots of significantly larger diameter than the diameter of the seed initiating their growth.Type: GrantFiled: February 6, 2020Date of Patent: February 18, 2025Assignees: INSTITUT POLYTECHNIQUE DE GRENOBLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPESInventors: Kader Zaidat, Christian Garnier, Ghatfan Hasan
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Patent number: 12228498Abstract: The invention is a device and method for detecting an analyte in a medium. An exciting light source produces an exciting light wave, which propagates to the medium and heats the latter. The device comprises a transducer for detecting the heating of the medium. According to one embodiment, the transducer is a thermal transducer, configured to detect a variation in the temperature of the medium. According to another embodiment, the transducer is an acoustic transducer, configured to detect a photoacoustic wave propagating from the medium. Whatever the embodiment, the transducer employs a membrane, on which a waveguide is placed. The waveguide comprises a resonant optical cavity. Transduction is achieved by analyzing a variation in a resonant wavelength of the optical cavity.Type: GrantFiled: December 24, 2020Date of Patent: February 18, 2025Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT POLYTECHNIQUE DE GRENOBLEInventors: Thomas Lauwers, Skandar Basrour, Jean-Guillaume Coutard, Alain Gliere, Guillaume Laffont
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Publication number: 20250052866Abstract: A lidar system based on measuring a time-of-flight, including: an emission device configured to emit light pulses towards a scene at an angle greater than or equal to 5°; a reception device including: o a photodetector configured to receive pulses reflected or backscattered by at least one element of the scene and to convert the pulses into an electrical signal, an amplification circuit configured to amplify the electrical signal, a processing unit for processing the amplified electrical signal, configured to digitize the amplified electrical signal and determine a distance from the at least one element based on the digitized amplified electrical signal, the amplification circuit including a transimpedance amplifier, a transformer including a primary and a secondary, a capacitor and an inductor arranged in series with the capacitor.Type: ApplicationFiled: December 16, 2022Publication date: February 13, 2025Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS-SACLAYInventor: Jean-Paul CROMIERES