Abstract: Micropeptides (miPEPs), or peptides coded by microRNAs, for promoting nodulation between a plant and a bacterium, as well as their use in this manner.
Type:
Grant
Filed:
March 25, 2021
Date of Patent:
January 7, 2025
Assignees:
UNIVERSITE TOULOUSE III-PAUL SABATIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Abstract: The present invention concerns modified nucleobases, nucleosides, deoxynucleosides, and/or their derivatives, nanocapsules comprising them, hydrogels and oleogels comprising said nanocapsules or said above-mentioned compounds and their uses, in particular their pharmaceutical uses.
Type:
Grant
Filed:
September 7, 2018
Date of Patent:
January 7, 2025
Assignees:
Universite D'Angers France, Institut National De La Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire D'Angers Cedex France
Inventors:
Marion Pitorre, Guillaume Bastiat, Jérôme Bejaud, Jean-Pierre Benoit
Abstract: The invention relates to a method for manufacturing an optoelectronic component substrate (12) comprising a stack of layers, the method comprising a step of: preforming a substrate (12) comprising a face which has a pattern with at least one zone made of a first material and one zone made of a second material, the two materials being thermosetting or thermoplastic materials, the first material being an electrically conductive material and the second material being an electrically insulating material, and molding by compression the face of the substrate (12) with a face of a reference element (22) having a surface roughness less than or equal to 50 nanometers.
Type:
Grant
Filed:
September 11, 2019
Date of Patent:
January 7, 2025
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PAUL SABATIER TOULOUSE III
Inventors:
Manuel Lopes, Benoit Schlegel, David Buso, Georges Zissis
Abstract: The invention relates to a device for identifying a fluorescent label. The detection device comprises nanowires, each nanowire acting as a transducer of fluorescence light into an electrical signal. One targeted application is sequencing of a nucleic acid.
Type:
Application
Filed:
June 26, 2024
Publication date:
January 2, 2025
Applicants:
Commissariat à l'Energie Atomique et aux Energies Alternatives, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPES
Inventors:
Olivier CONSTANTIN, Moira HOCEVAR, Pascal MAILLEY, Eva MONROY
Abstract: Identification of at least one microorganism present in a sample based on the detection of peptides issued from the cleavage of ribosomal proteins of said microorganism, comprising lysis of microorganism(s) and cleavage of the proteins, obtaining a mixture of peptides, decomplexing the peptide mixture using a liquid separation device coupled with a mass spectrometer, nebulizing the liquid to produce an ion current, receiving the ion current from the ion source, executing on the ion current a series of filtering steps for detecting a transition, receiving data on the transitions, assigning the transitions associated with peptides into two or more contiguous groups, monitoring, and optionally generating a chromatogram or electropherogram, wherein the microorganism is identified according to the detection of said peptide(s).
Type:
Application
Filed:
July 15, 2022
Publication date:
January 2, 2025
Applicants:
Université Claude Bernard Lyon 1, Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM), Ecole Normale Superieure de Lyon, Hospices Civils de Lyon
Abstract: A method and system for characterizing media, in particular dielectric media, using a multifrequency resonator that is positioned remote from the region to be characterized and which is excited and interrogated remotely via inductive coupling to a probe. A reader measures, via a single channel, the complex impedance of this probe when it is coupled to the resonator and when this resonator interacts magnetically with the region to be characterized. The impedance is spectrally analyzed in order to extract therefrom individual complex impedances for each of the resonance frequencies of the resonator. These individual impedances are processed in order to calculate electrical properties of the medium, such as permittivity and/or conductivity, which provide information on the nature and/or change of the medium. Also, a multifrequency resonator provided for such a system or method.
Type:
Application
Filed:
November 18, 2022
Publication date:
January 2, 2025
Applicants:
UNIVERSITE PARIS-SACLAY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CY CERGY PARIS UNIVERSITÉ
Inventors:
Alexiane PASQUIER, Yohan LE DIRAISON, Stéphane SERFATY, Pierre-Yves JOUBERT
Abstract: Embodiments of the disclosure relate to a composition including 70 to 95 parts by weight of an epoxide resin having a viscosity of between 1 and 150 kPa·s at a temperature of between 20° C. and 25° C., and 5 to 30 parts by weight, per 100 parts by weight of resin present in the composition, of a curing agent dispersed in the resin, the curing agent being an ionic liquid containing a phosphonium cation. The disclosure also relates to a semi-finished product or towpreg, including a bundle of fibres and a composition. The disclosure also relates to the use of a composition or of a semi-finished product according to the disclosure for the production of a hydrogen tank, in particular a type IV pressure tank, made of composite material, for the on-board storage of hydrogen gas.
Type:
Application
Filed:
November 16, 2022
Publication date:
January 2, 2025
Applicants:
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE LYON, VITECH COMPOSITES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD – LYON1, UNIVERSITE JEAN MONNET SAINT ETIENNE
Abstract: A computer-implemented method for assisting a general anesthesia or a sedation of a subject, having receiving an electroencephalogram EEG signal of a subject, processing the EEG signal including ?-bands for defining for each instant of a plurality of instants, a part of the signal has in a time window having the instant, the part of the signal being related to the instant, determining for each instant, a distribution of a power of the part of the signal as a function of the frequency, determining for each instant a maximum power frequency as a frequency of maximum power in the distribution, the maximum power frequency being related to the instant, detecting a reference instant, so that the maximum power frequency as a function of time takes higher values before the reference instant than after, detecting in a time frame following the reference instant, an alpha instant corresponding to a first occurrence of a suppression of an ?-band, estimating a first parameter as the duration between the reference inst
Type:
Application
Filed:
July 26, 2022
Publication date:
January 2, 2025
Applicants:
PARIS SCIENCES ET LETTRES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, NATIONAL INSTITUTE OF HEALTH AND MEDICAL RESEARCH, ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS
Inventors:
David HOLCMAN, Matteo DORA, Christophe SUN
Abstract: A process for preparing a compound of formula (NaOH)x[Fe(OH)2]yFeS, may include: (a) mixing iron and sodium sulfide in equimolar amounts, in an NaOH aqueous solution; (b) heating the obtained mixture up to a temperature in a range of from 110 to 210° C. for a duration in a range of from 1 hour to 1 week; and (c) recovering the active material by filtering and drying in a neutral atmosphere.
Type:
Application
Filed:
September 21, 2022
Publication date:
January 2, 2025
Applicants:
AMPERE S.A.S., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Ecole Nationale Supérieure de Chimie de Paris
Inventors:
Philippe BARBOUX, Mohamed CHAKIR, Domitille GIAUME, Ine HAUGLAND-GOSLING, Caroline MIR
Abstract: An array device composed of individual multifrequency passive resonators which are not electrically connected to one another. These resonators are formed by interrupted transmission lines that close back in on themselves and which are nested within one another, each formed of a group of two or more parallel tracks, and are paired with one another contactlessly around one or more dielectric layers of a substrate. Such an array is used in particular to modify an incident magnetic or electromagnetic field, and/or to carry out impedance matching by being placed between an incident field and a body or object to be treated or observed. It is also used to improve a method for contactlessly characterizing a medium to be investigated, via inductive coupling of one or more of the resonators of said array to a probe connected to a reader.
Type:
Application
Filed:
November 18, 2022
Publication date:
January 2, 2025
Applicants:
UNIVERSITE PARIS-SACLAY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CY CERGY PARIS UNIVERSITÉ
Inventors:
Pierre-Yves JOUBERT, Yohan LE DIRAISON, Alexiane PASQUIER, Stéphane SERFATY
Abstract: Electroacoustic device having a transducer including a piezoelectric substrate, first and second electrodes of inverse polarity having respective first and second tracks provided on said substrate, the first and second tracks spiraling around a same center (C), the transducer being configured for generating a swirling ultrasonic surface wave in the substrate.
Type:
Grant
Filed:
June 16, 2023
Date of Patent:
December 31, 2024
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LILLE, ECOLE CENTRALE DE LILLE, SORBONNE UNIVERSITE
Inventors:
Michaël Aymeric Baudoin, Olivier Khalil Nizar Bou Matar-Lacaze, Antoine Jean-Pierre Riaud, Jean-Louis Pierre Thomas
Abstract: The application relates to a device for collecting a sample of intestinal fluid comprising a polymeric inner material having an at least partially compressed open cell structure, having a volume Vi and being suitable for swelling to a volume greater than or equal to 1.1×Vi by absorbing intestinal fluid, said material being encased with an elastic polymeric casing impervious to digestive fluid, said casing comprising at least one opening allowing the intake of intestinal fluid into the inner material, a gastro-resistant material suitable for dissolving in intestinal fluid at 37° C. being disposed on top of each opening, and at least one mechanism for closing the opening(s).
Type:
Grant
Filed:
October 24, 2018
Date of Patent:
December 31, 2024
Assignees:
UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
Inventors:
Jacques Thelu, Philippe Cinquin, Donald Keith Martin, Thomas Soranzo, Jean-Pierre Alcaraz, Jean-Marc Kweter
Abstract: A method for identifying a microorganism to be identified, which includes the following steps: obtaining an Excitation-Emission EEM of the microorganism to be identified, analysing the main components of the EEM matrix using at least one reference EEMr matrix, projecting the result of the analysis onto a plane defined by two main components, and identifying the microorganism to be identified.
Type:
Grant
Filed:
November 27, 2020
Date of Patent:
December 31, 2024
Assignees:
UNIVERSITE DU MANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS-, CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS, UNIVERSITE D'ANGERS
Abstract: Various embodiments may provide an optical fiber for sensing an analyte. The optical fiber may include a dielectric core wall defining a hollow space. The optical fiber may also include a cladding layer surrounding the dielectric core wall and spaced apart from the dielectric core wall. The optical fiber may further include a plurality of supports extending from the cladding layer to the dielectric core wall. A thickness of the dielectric core wall may be greater than a thickness of each of the plurality of supports. The dielectric core wall may be configured to carry an optical light for sensing the analyte.
Type:
Grant
Filed:
March 31, 2020
Date of Patent:
December 31, 2024
Assignees:
Agency for Science, Technology and Research, Centre National de la Recherche Scientifique, Université de Limoges
Inventors:
Dinish Unnimadhava Kurup Soudamini Amma, Malini Olivo, Georges Humbert, Flavien Beffara, Jean-Louis Auguste
Abstract: A Tamm electromagnetic cavity (10, 20, 30, 40, 60) possessing a resonant frequency in the THz domain, comprising: an interference mirror that is reflective in the THz domain, this mirror consisting of a stack of dielectric layers (7) comprising an alternation, in a z-direction, of two different layers, a layer referred to as the layer of high refractive index (2) and a layer referred to as the layer of low refractive index (4), the index of the layer of low refraction being lower than that of the layer of high refractive index, and being manufactured by stacking layers mechanically or by joining dielectric layers to one another; an upper metal layer (5) deposited on or added to an upper dielectric layer of said interference mirror so as to form a structure that supports at least one Tamm mode in the THz domain, the upper metal layer (5) being structured so as to form an antenna possessing a resonant frequency equal to that of the electromagnetic cavity.
Type:
Grant
Filed:
April 3, 2020
Date of Patent:
December 31, 2024
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, SORBONNE UNIVERSITE, ECOLE NORMALE SUPERIEURE DE PARIS, UNIVERSITE DE PARIS
Abstract: An active implantable medical device including, once implanted, a module external to the patient and a module inside the patient, the external module and the internal module being intended to transfer energy and data from one to the other. Also, a method for transferring energy and data, the method being implemented by the active implantable medical device.
Type:
Grant
Filed:
September 24, 2021
Date of Patent:
December 31, 2024
Assignees:
NEURINNOV, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INRIA—INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET EN AUTOMATIQUE, UNIVERSITÉ DE MONTPELLIER
Inventors:
David Andreu, David Guiraud, Brice Sorli, Arnaud Vena
Abstract: A method for determining a profile of stimulation charge rate for at least one muscle or group of muscles of a subject using the ergometer equipped with a FES system, the profile of stimulation charge rate being specific to the ergometer user. Also, a method for stimulation intervals for at least one muscle or group of muscles of a subject using the ergometer equipped with a FES system. Further, an ergometer, preferably a cyclic ergometer such as an electric stimulation stationary bike, including a FES controller with instructions to operate the method.
Type:
Application
Filed:
September 16, 2022
Publication date:
December 26, 2024
Applicants:
KURAGE, ECOLE NORMALE SUPERIEURE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS
Abstract: A quantum simulator to simulate an evolution of a solution of a complex nonlinear equation. The quantum simulator includes a first wavelength-tunable laser configured to emit light with a tunable central wavelength; a vapor cell comprising a gas of atoms or molecules at a given temperature; a beam shaper unit arranged between the wavelength-tunable laser and the vapor cell and configured to modify the phase and/or the amplitude of the emitted light. The vapor cell is configured to receive light at the output of the beam shaper unit so that the light interacts with the gas to produce an output light; the interaction mapping the complex nonlinear equation with given initial conditions and coefficient data of the complex nonlinear equation.
Type:
Application
Filed:
October 12, 2022
Publication date:
December 26, 2024
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ CÔTE D'AZUR
Abstract: The invention relates to a method for depositing an environmental barrier on a part made of composite material having a ceramic matrix comprising silicon carbide fibres. The method comprises the deposition of a joining layer on at least one surface of the part, the joining layer comprising mullite or a mullite precursor, and the deposition of a protective layer on the joining layer, the protective layer comprising a rare earth disilicate.
Type:
Application
Filed:
October 26, 2022
Publication date:
December 26, 2024
Applicants:
SAFRAN CERAMICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUX
Inventors:
Francis REBILLAT, Lisa PIN, Marie SALLES, Eric BOUILLON