Patents Assigned to Centre National de la Recherche Scientifique
  • Publication number: 20220390458
    Abstract: The invention relates a fluorescent compound of formula I: wherein A is selected from P, P?O and N; ·R1 is a residue comprising an oxygen atom·R2 is a residue comprising an oxygen atom, or a halogen, ·R3, R4 and R5 are alkyls, possibly substituted or a salt or a solvate thereof. The compound is useful as a fluorescent probe sensitive to membrane fluidity and for diagnosing cancer.
    Type: Application
    Filed: September 22, 2020
    Publication date: December 8, 2022
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE CLAUDE BERNARD LYON 1, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, CPE LYON FORMATION CONTINUE ET RECHERCHE pouvant être précédée ou suivie par CPE LYON FCR, CENTRE LEON BERARD, HOSPICES CIVILS DE LYON
    Inventors: Thierry GRANJON, Ofelia MANITI, Olivier MARCILLAT, Peter GOEKJIAN, Mouhedine CHENIOUR, Arnaud VIGNERON, David GUEYRARD, Sébastien IBANEZ
  • Patent number: 11520059
    Abstract: A detector of high-energy (higher than 100 eV) ionising radiation, including an optical fibre having an outside diameter, called the fibre diameter, smaller than 250 microns, including a fibre core, a first cladding, called the useful cladding, encircling the fibre core and a second cladding, called the protective cladding, encircling the useful cladding, and a scintillating layer provided to convert the ionising radiation into light; including a portion, called the detecting portion, arranged in a length of the fibre and having a void formed in the protective cladding, in the useful cladding, and possibly in the fibre core, the scintillating layer being arranged in the void in contact with the useful cladding and the fibre core.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: December 6, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE FRANCHE-COMTE
    Inventor: Thierry Grosjean
  • Publication number: 20220383083
    Abstract: This method for training a binarized neural network, also called BNN, including neurons, with a binary weight for each connection between two neurons, is implemented by an electronic circuit and comprises: a forward pass including calculating an output vector by applying the BNN on an input vector; a backward pass including computing an error vector from the calculated output vector, and calculating a new value of the input vector by applying the BNN on the error vector; a weight update including computing a product by multiplying an element of the error vector with one of the new value of the input vector, modifying a latent variable depending on the product; and updating the weight with the latent variable; each weight being encoded using a primary memory component; each latent variable being encoded using a secondary memory component having a characteristic subject to a time drift.
    Type: Application
    Filed: May 23, 2022
    Publication date: December 1, 2022
    Applicants: Commissariat à l'énergie atomique et aux énergies alternatives, Centre national de la recherche scientifique, UNIVERSITE PARIS-SACLAY
    Inventors: Tifenn HIRTZLIN, Damien QUERLIOZ, Elisa VIANELLO
  • Patent number: 11512022
    Abstract: A nanoporous carbon-loaded cement composite that conducts electricity. The nanoporous carbon-loaded cement composite can be used in a variety of different fields of use, including, for example, a structural super-capacitor as an energy solution for autonomous housing and other buildings, a heated cement for pavement deicing or house basement insulation against capillary rise, a protection of concrete against freeze-thaw (FT) or alkali silica reaction (ASR) or other crystallization degradation processes, and as a conductive cable, wire or concrete trace.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: November 29, 2022
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE BORDEAUX
    Inventors: Roland J. M. Pellenq, Aikaterini Ioannidou, Nicolas Chanut, Thibaut Divoux, Renal Backov, Franz-Josef Ulm
  • Patent number: 11515394
    Abstract: A method for the nanoscale etching of a layer of Ge1-xSnx on a carrier for a FET transistor, x being the concentration of tin in the GeSn alloy, the etching method includes a step of plasma-etching the layer of Ge1-xSnx using a mixture comprising dichlorine (Cl2) and dinitrogen (N2) and under an etching pressure lower than or equal to 50 mTorr, preferably lower than or equal to 10 mTorr. A method for producing a conduction channel on a carrier for a FET transistor, comprising a step of forming a layer of Ge1-xSnx on the carrier, the layer being produced by epitaxial growth, and a step of etching the layer of Ge1-xSnx according to the etching method. A conduction channel made of Ge1-xSnx for a FET transistor, the channel being obtained according to the production method, and a FET transistor comprising a plurality of conduction channels made of Ge1-xSnx.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: November 29, 2022
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Etienne Eustache, Bassem Salem, Jean-Michel Hartmann, Franck Bassani, Mohamed-Aymen Mahjoub
  • Publication number: 20220373718
    Abstract: The present invention relates to an optical device (1) suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum, said device (1) comprising at least: a first coating layer (10) made of a first material, a substrate (50) made of a material that is different from the first material, and surface texturing (60) forming cavities (61) in the device (1); wherein a lower layer (50) disposed directly below the first coating layer (10) is either a second coating layer (20) made of a material that is different from the first material, or the substrate (50); wherein the lower layer (50) has a determined thickness (E50); characterised in that the cavities (61) extend through the coating layer (20) and are sunk into the lower layer (50) through at least part of the thickness (E50).
    Type: Application
    Filed: October 26, 2020
    Publication date: November 24, 2022
    Applicants: Hydromecanique et Frottement, Manutech-USD, Université Jean Monnet Saint-Etienne, Centre National de la Recherche Scientifique
    Inventors: Thomas KÄMPFE, Laurent DUBOST, Xxx SEDAO
  • Publication number: 20220369618
    Abstract: The disclosure relates to an apparatus and a system for testing the cognitive ability of a rodent, comprising a testing chamber, a retarding zone connected to the entrance chamber and including at least one obstacle configured to slow down the rodent's movement to the entrance chamber, and an optional transfer chamber connected to the entrance chamber via the retarding zone for transfer of the rodent to and from an area external to the apparatus. The testing chamber comprises an entrance chamber, a plurality of corridors each connected to the entrance chamber via a corridor's first end portion, and at least one odor diffuser for diffusing odors in the plurality of corridors.
    Type: Application
    Filed: October 22, 2020
    Publication date: November 24, 2022
    Applicants: Université d'Aix Marseille (AMU), Centre National de la Recherche Scientifique
    Inventors: François Silvio Paul Hubert Roman, Guy Pierre Roger Escoffier
  • Publication number: 20220370996
    Abstract: The present invention relates to a method for producing a support at least micrometric in size, photocatalytically active and at least in the visible range, containing nanocrystals each composed of from 80 to 100 mol % of TiO2 and from 0 to 20 mol % of at least one other metal or semi-metallic oxide, comprising the following steps, from an acidic aqueous reaction medium, at a heating temperature of between 20 and 60° C.
    Type: Application
    Filed: June 30, 2020
    Publication date: November 24, 2022
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CY CERGY PARIS UNIVERSITÉ, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Nicolas PASTERNAK, Nancy LINDER
  • Patent number: 11504049
    Abstract: A kit of two compositions comprising the same odorants in mixtures of different proportions is used for the measurement of olfactory discrimination capacity in subjects affected by a psychiatric disorder or disease involving mood disturbance, more particularly mood depression.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: November 22, 2022
    Assignees: INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Francoise Lazarini, Pierre-Marie Lledo, Eleni Siopi, Raphael Servignat D'Aout
  • Patent number: 11504424
    Abstract: The present invention relates to an attenuated virus strain derived from a human metapneumovirus strain comprising the genome sequence represented by sequence SEQ ID NO. 1, said attenuated strain comprising one or more genetic modifications of said sequence SEQ ID NO. 1 attenuating the virulence of said strain.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: November 22, 2022
    Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NORMALE SUPERIEURE DE LYON, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE LAVAL
    Inventors: Manuel Rosa-Calatrava, Guy Boivin, Julia Dubois, Mario Andres Pizzorno, Olivier Terrier, Marie-Eve Hamelin, Marie-Helene Cavanagh
  • Patent number: 11505508
    Abstract: A part includes a substrate having, adjacent to a surface of the substrate, at least a portion that is made of a material that contains silicon, and an environmental barrier formed on the surface of the substrate, the environmental barrier including a first layer including at least one first rare earth silicate and presenting grains with a mean size less than or equal to 1 ?m; and a second layer covering the first layer, the second layer including at least one rare earth silicate and presenting grains with a mean size greater than 1 ?m.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: November 22, 2022
    Assignees: SAFRAN CERAMICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE BORDEAUX
    Inventors: Lisa Pin, Simon Arnal, Francis Rebillat, Fabrice Mauvy
  • Publication number: 20220365330
    Abstract: The disclosure may relate to a method for the characterization of the 3D orientation of an emitting dipole within a specimen. The method comprises splitting a light beam emitted by the emitting dipole and exiting an objective lens into a first and a second beams; spatially filtering said first beam by using a spatial frequency filter; splitting each of said filtered first beam and said second beam into two beams linearly polarized using polarizing beam splitters; detecting with an optical detection unit four beams linearly polarized in a detection plane optically conjugated with the front focal plane of said microscope objective lens; determining, from four intensity images, in a predefined frame of the specimen, the mean orientation and the angular aperture of the distribution of the 3D orientation of the emitting dipole, during an acquisition time of said four intensity images.
    Type: Application
    Filed: September 28, 2020
    Publication date: November 17, 2022
    Applicants: Université d'Aix-Marseille, Centre National de la Recherche Scientifique, CENTRALE MARSEILLE
    Inventors: Sophie Brasselet, Valentina Curcio
  • Publication number: 20220361896
    Abstract: A medical device for penetrating a bone structure including a processing unit having a transfer function that associates an electrical conductivity value S with a depth value d, wherein the processing unit is configured to detect a threshold selected from amongst an absolute threshold, a relative threshold and a critical gradient, and to emit a warning signal and/or control signal responsive to detection of the threshold.
    Type: Application
    Filed: May 2, 2022
    Publication date: November 17, 2022
    Applicants: SpineGuard, Sorbonne Universite, Centre National de la Recherche Scientifique - CNRS, INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Stephane BETTE, Jimmy DA SILVA, Thibault CHANDANSON, Guillaume MOREL, Maurice BOURLION
  • Publication number: 20220364981
    Abstract: The invention is a device and method for detecting an analyte in a medium. An exciting light source produces an exciting light wave, which propagates to the medium and heats the latter. The device comprises a transducer for detecting the heating of the medium. According to one embodiment, the transducer is a thermal transducer, configured to detect a variation in the temperature of the medium. According to another embodiment, the transducer is an acoustic transducer, configured to detect a photoacoustic wave propagating from the medium. Whatever the embodiment, the transducer employs a membrane, on which a waveguide is placed. The waveguide comprises a resonant optical cavity. Transduction is achieved by analyzing a variation in a resonant wavelength of the optical cavity.
    Type: Application
    Filed: December 24, 2020
    Publication date: November 17, 2022
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT POLYTECHNIQUE DE GRENOBLE
    Inventors: Thomas LAUWERS, Skandar BASROUR, Jean-Guillaume COUTARD, Alain GLIERE, Guillaume LAFFONT
  • Publication number: 20220365249
    Abstract: The present invention relates to an optical device (1), suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum, said device (1) comprising at least: a substrate (10) made of a first material, a coating layer (20) made of a second material that is different from the first material, and surface texturing (30) forming cavities (31) in the device (1), characterized in that the cavities (31) extend through the coating layer (20) and are partially sunk into the substrate (10).
    Type: Application
    Filed: October 26, 2020
    Publication date: November 17, 2022
    Applicants: Hydromecanique et Frottement, Manutech-USD, Université Jean Monnet Saint-Etienne, Centre National de la Recherche Scientifique
    Inventors: Thomas KÄMPFE, Laurent DUBOST, Xxx SEDAO
  • Patent number: 11497384
    Abstract: An optical fibre having a functionalised distal exploration end including a sheath, and a ferrule rigidly connected to the sheath at the distal exploration end, characterised in that the distal exploration end has a functionalised head which is removably attached on the ferrule. Also, a method of assembling the optical fibre.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: November 15, 2022
    Assignees: KAMAX INNOVATIVE SYSTEM, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LIMOGES
    Inventors: Jérôme Desroches, Olivier Baudet, Martine Lejeune, Romain Trihan, Fabrice Lalloue
  • Patent number: 11499002
    Abstract: A multi-epoxidized biphenyl compound has the formula (I) below wherein R, R1, R2 and R3 are as defined in the description, as well as mixtures of at least two of the compounds. These multi-epoxidized biphenyl compounds are fully suitable as main constituents of thermosetting epoxy resins, i.e. as polyepoxides precursors. They are beneficial substitutes for bisphenol A diglycidyl ether.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: November 15, 2022
    Assignees: ARIANEGROUP SAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Etienne Savonnet, Brigitte Defoort, Henri Cramail, Stéphane Grelier, Etienne Grau
  • Patent number: 11499197
    Abstract: The invention relates to a method for in vitro predicting the outcome of an individual having a multiple myeloma, comprising the steps of: a. measuring the expression level of genes coding for kinases, b. calculating a score value for each genes; and c. classifying the individual as having a good or a bad outcome.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: November 15, 2022
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER, UNIVERSITÉ DE MONTPELLIER
    Inventors: Jerome Moreaux, Hugues De Boussac, Alboukadel Kassambara
  • Patent number: 11498877
    Abstract: A method of treating at least one silicon carbide fibre, the method including a) formation of a silica layer at the surface of a silicon carbide fibre having an oxygen content less than or equal to 1% in atomic percentage, the silica layer being formed by contacting this fibre with an oxidizing medium having a temperature greater than or equal to 50° C. and pressure greater than or equal to 1 MPa, and b) removal of the silica layer formed by hydrothermal treatment of the fibre obtained after implementation of step a) in which the fibre is treated with water at a pressure between saturating vapour pressure and 30 MPa and at a temperature less than or equal to 400° C.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: November 15, 2022
    Assignees: SAFRAN CERAMICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Sylvie Loison, Lucile Henry, Cyril Aymonier, Chrystel Huguet
  • Patent number: 11498890
    Abstract: Process for the conversion of non-oxidative coupling of methane to ethylene, under non-oxidative conditions, comprising: providing a first stream containing at least 50 vol. % of methane based on the total volume of said first stream; providing a catalyst; putting in contact said first stream with said catalyst at a weight hour space velocity ranging from 0.5 to 100 h?1, a temperature ranging from 500° C. to 1100° C. and a pressure ranging from 0.1 MPa to 5 Mpa in the absence of oxygen; recovering a second stream containing unconverted methane if any, ethylene and hydrocarbons having at least 2 carbon atoms. Said process is remarkable in that said catalyst is a synthetic zeolite material, containing at least one metal M with silicon to metal M molar ratio Si/M as determined by inductively coupled plasma optical emission spectrometry ranging from 100 to 65440 and in that said metal M is incorporated inside of the zeolite tetrahedral sites.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: November 15, 2022
    Assignees: TOTALENERGIES ONETECH, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Florent Dubray, Svetlana Mintova, Jean-Pierre Gilson, Stanislav Konnov, Stijn Van Daele, Nikolai Nesterenko