Patents Assigned to Centre National de la Recherche Scientifique
  • Patent number: 10788549
    Abstract: An antenna array includes a plurality of linear electromagnetic resonators having longitudinal axes oriented parallel to one another and not aligned, and at least one decoupling device arranged between two the linear electromagnetic resonators, wherein the decoupling device comprises a plurality of open-loop electromagnetic resonators that are matched to a frequency located in the bandwidth of the two the adjacent linear electromagnetic resonators, that are electrically insulated and that are arranged in a plurality of planes that are not parallel to a plane containing the longitudinal axes of the two the linear electromagnetic resonators. Nuclear magnetic resonance imaging apparatus comprising such an antenna array is also provided.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: September 29, 2020
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX-MARSEILLE
    Inventors: Elodie Georget, Michel Luong, Alexandre Vignaud, Eric Giacomini, Edouard Chazel, Redha Abdeddaim, Stefan Enoch, Gérard Tayeb
  • Patent number: 10790634
    Abstract: A laser system with optical feedback, includes an optical-feedback-sensitive laser which emits, via an output optical fibre, a continuous, frequency-adjustable, propagating, source optical wave, known as the source wave; a resonant optical cavity coupled by means of optical feedback to the laser and configured to generate an intra-cavity wave, one fraction of which returns to the laser in the form of a counter-propagating optical wave; an electro-optic fibre modulator placed on the optical path between the laser and the resonant optical cavity, the electro-optic modulator being configured to generate a phase-shifted source wave by phase-shifting the source wave and, by phase-shifting the counter-propagating optical wave, to generate a phase-shifted counter-propagating wave, known as the feedback wave, which reaches the laser; a phase-control device for generating a control signal for the electro-optic modulator from an error signal representative of the relative phase between the source wave and the feedback
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: September 29, 2020
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventor: Samir Kassi
  • Patent number: 10787493
    Abstract: The present invention relates to a modified cytokine of the TNF superfamily, with reduced activity to its receptor, wherein said modified cytokine is specifically delivered to target cells. Preferably, said modified cytokine is a single chain variant of the TNF superfamily, even more preferably, one or more of the chains can-y one or more mutations, resulting in a low affinity to the receptor, wherein said mutant cytokine is specifically delivered to target cells. The targeting is realized by fusion of the modified cytokine of the TNF superfamily to a targeting moiety, preferably an antibody or antibody-like molecule. The invention relates further to the use of such targeted modified cytokine of the TNF superfamily to treat diseases.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: September 29, 2020
    Assignees: VIB VZW, UNIVERSITEIT GENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITË DE MONTPELLIER, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE MONTPELLIER
    Inventors: Jan Tavernier, Jennyfer Bultinck, Frank Peelman, Gilles Uze
  • Patent number: 10788497
    Abstract: A method which can be used to analyse oxidising species in a sample, including: placing the sample in contact with a first photoluminescent agent, and a second optically active agent, at least the first photoluminescent agent including nanoparticles doped with rare earth elements and being oxidisable, the luminescence of the first photoluminescent agent varying, at least at one first wavelength, with the amount of oxidising species, and the signal emitted by the second optically active agent being constant or varying, at least at one second wavelength other than the first wavelength, with the amount of oxidising species in a direction opposite to the luminescence of the first photoluminescent agent; energising the first and second agents in the sample; measuring the light intensity of the sample at least at the first and second wavelengths; and assessing the presence and/or the amount of oxidising species by interpreting the measured light intensities.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: September 29, 2020
    Assignees: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Cédric Bouzigues, Mouna Abdesselem, Antigoni Alexandrou, Thierry Gacoin, Jean-Pierre Boilot
  • Publication number: 20200297263
    Abstract: A method for determining the focus of the visual attention of an individual from electroencephalographic signals. At least one visual stimulus to be displayed is generated from at least one graphical object, a visual stimulus being an animated graphical object obtained by applying to a graphical object a temporal succession of elementary transformations that is temporally parameterized by a corresponding modulation signal. From a plurality of electroencephalographic signals produced by the individual focusing his visual attention to one of the visual stimuli, a modulation signal is reconstructed. A visual stimulus corresponding to the modulation signal for which the degree of statistical dependence with the reconstructed modulation signal is higher than a first threshold is identified.
    Type: Application
    Filed: September 6, 2018
    Publication date: September 24, 2020
    Applicants: Centre National de la Recherche Scientifique, ECOLE NORMALE SUPERIEURE DE PARIS, Ecole des Hautes Etudes en Sciences Sociales
    Inventors: Sid KOUIDER, Jean-Maurice LEONETTI, Nicolas BARASCUD, Robin ZERAFA
  • Publication number: 20200299653
    Abstract: The disclosure pertains to the field of molecular means capable of binding to, and preferably of chelating, cGMP, appropriate for use in vitro or in vivo and preferably capable of targeting specific cellular compartments. The polypeptides of the disclosure comprise a chimeric construction derived from the N terminus part of PKG-I? and PKG-I?, and the two cGMP binding sites of the wild type PKG.
    Type: Application
    Filed: November 2, 2018
    Publication date: September 24, 2020
    Applicants: SORBONNE UNIVERSITÉ, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Xavier Nicol, Oriol Ros Torres
  • Publication number: 20200300100
    Abstract: A turbine component such as a turbine blade or a vane of a distributor, which includes a polycrystalline substrate containing grains, the substrate having at least one Ti3AlC2 phase and the mass fraction of the phase of the alloy is greater than 97%, with the average length of the grains is less than 50 ?m, the average width-to-length ratio is between 0.4 and 0.6, and the average mesh volume of the Ti3AlC2 phase is less than 152.4 ?3.
    Type: Application
    Filed: September 21, 2018
    Publication date: September 24, 2020
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), SAFRAN
    Inventors: Pierre SALLOT, Veronique BRUNET, Jonathan CORMIER, Elodie Marthe Bernadette DROUELLE, Sylvain Pierre DUBOIS, Patrick VILLECHAIS
  • Patent number: 10781457
    Abstract: The disclosure relates to a method for increasing the resistance of a plant to a plant RNA virus, comprising expressing in said plant a mutant protein-only RNase P enzyme lacking a nuclear localization signal domain or an organelle targeting sequence domain, and related compositions.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: September 22, 2020
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Philippe Giege, Anthony Gobert
  • Patent number: 10780435
    Abstract: Disclosed is a minifluidic device including a matrix, an elongated guiding duct embedded at least in part in the matrix, with at least one port to the outside of the matrix, a movable fiber at least partly contained in the guiding duct, and able to undergo within the guiding duct, and at least along some part of the fiber, at least one action selected among a sliding, or a deformation, or a rotation and at least one of the movable fiber or the guiding duct is elastic or is non linear along at least part of its length, or at least part of the matrix is elastic.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: September 22, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE PIERRE ET MARIE CURIE
    Inventors: Bastien Venzac, Ayako Yamada, Jean-Louis Viovy, Stephanie Descroix, Laurent Malaquin
  • Patent number: 10779726
    Abstract: An eye-movement determination method includes providing an a touch display and a memory that stores an image that includes a point of interest, wherein the image is a stored image, and repeatedly executing a set of steps. The steps include determining a position of a contact point, locating a corresponding position in an image that is displayed on the touch display, generating a degraded image from the stored image, displaying the degraded image on the touch display, and recording successive positions of the contact point. The contact point is a point at which a user contacts the touch display. The degraded image is substantially identical to the stored image with a clear zone but degrades beyond the clear zone.
    Type: Grant
    Filed: December 27, 2016
    Date of Patent: September 22, 2020
    Assignees: Centre National de la Recherche Scientifique, UNIVERSITE CLAUDE BERNARD LYON 1
    Inventors: Angela Sirigu, Jean-René Duhamel, Guillaume Lio
  • Publication number: 20200288943
    Abstract: An optical fibre having a functionalised distal exploration end including a sheath, and a ferrule rigidly connected to the sheath at the distal exploration end, characterised in that the distal exploration end has a functionalised head which is removably attached on the ferrule. Also, a method of assembling the optical fibre.
    Type: Application
    Filed: May 15, 2018
    Publication date: September 17, 2020
    Applicants: KAMAX INNOVATIVE SYSTEM, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LIMOGES
    Inventors: Jérôme DESROCHES, Olivier BAUDET, Martine LEJEUNE, Romain TRIHAN, Fabrice LALLOUE
  • Publication number: 20200292247
    Abstract: The present invention concerns a method of refrigerating a housing to a target temperature according to which: an evaporator is placed in said housing; said evaporator is placed in fluid communication with a thermochemical reactor Ri, simultaneously, the heat produced at said reactor Ri is evacuated; Characteristically, at least n>1 other thermochemical reactors are provided; I) the pressure Pevi in said evaporator after it is placed in fluid communication with said thermochemical reactor Ri, and the temperature of said thermochemical reactor Ri connected to said evaporator, are determined; II) when the temperature difference DTRi between the temperature of said reactor Ri connected to said evaporator and the equilibrium temperature TeSi of said reactive mixture contained in said thermochemical reactor Ri at the pressure Pevi of said evaporator is equal to a first predetermined differential and/or when the temperature difference DTev between said evaporator and the interior of said housing is equ
    Type: Application
    Filed: September 7, 2018
    Publication date: September 17, 2020
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Aleix PUBILL, Laurent RIGAUD, David TADIOTTO, Driss STITOU, Nathalie MAZET
  • Patent number: 10777833
    Abstract: An electrolyte membrane including (i) a porous mat of nanofibres, wherein the nanofibres are composed of a non-ionically conducting heterocyclic-based polymer, the heterocyclic-based polymer comprising basic functional groups and being soluble in organic solvent; and (ii) an ion-conducting polymer which is a partially- or fully-fluorinated sulphonic acid polymer. The porous mat is essentially fully impregnated with ion-conducting polymer, and the thickness of the porous mat in the electrolyte membrane is distributed across at least 80% of the thickness of the electrolyte membrane. Such a membrane is of use in a proton exchange membrane fuel cell or an electrolyser.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: September 15, 2020
    Assignees: Johnson Matthey Fuel Cells Limited, Centre National de la Recherche Scientifique, Universite de Montpellier
    Inventors: Deborah Jones, Jacques Roziere, Sara Cavaliere, Surya Subianto, Sarah Burton
  • Patent number: 10775702
    Abstract: Disclosed is a lithography process on a sample with at least one emitter, the process including: putting at least one layer of resist above the sample; exciting one selected emitter with light through the at least one layer of resist; detecting light emitted by the excited selected emitter and determining a position of the selected emitter; and curing with a light beam a part of the at least one layer of resist above the position of the selected emitter, the light beam being a shaped light beam having a cross-section, this cross-section having a central part, an intermediate part surrounding the central part and a border part surrounding the intermediate part, the intensity of the shaped light beam on the at least one layer of resist reaching a maximum at the intermediate part.
    Type: Grant
    Filed: February 12, 2018
    Date of Patent: September 15, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE, UNIVERSITE DE PARIS
    Inventors: Agnès Maitre, Amit Raj Dhawan, Pascale Senellart, Cherif Belacel
  • Patent number: 10772930
    Abstract: The present invention relates to an isolated bacterium from the genus Pseudoalteromonas for its use as a probiotic, the use of said strain as a preservative, cyclolipopeptides which may be obtained from this bacterium, a composition comprising at least such a cyclolipopeptide, as well as to their uses.
    Type: Grant
    Filed: March 27, 2018
    Date of Patent: September 15, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE DE RENNES 1, UNIVERSITE DE BRETAGNE OCCIDENTALE
    Inventors: Florie Desriac, Yannick Fleury, Patrick Le Chevalier, Delphine Destoumieux, Matthieu Simon
  • Patent number: 10772985
    Abstract: The invention relates to a device for adsorbing odours comprising an absorbent layer and an adsorbent layer, said adsorbent layer being provided with a material permeable to volatile organic compounds (VOCs) and an adsorbent particulate filler comprising at least one spice. Such a device is particularly useful for adsorbing and masking body odours.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: September 15, 2020
    Assignees: Institut Corie, Ecole Superieore De Physique Et De Chimie Industrielle (ESPCI), Cole Nationale Superieore De Chime De Paris (ENSCP), Centre National De La Recherche Scientifique, Cemag Care
    Inventors: Aurélie Thuleau, Isabelle Fromantin, Vincent Semetey, José Dugay, Jean-François Le Meur
  • Publication number: 20200283344
    Abstract: A method for preparing polycrystalline fluoride ceramics using powder of fluoride ceramics nanocrystallites as starting material, wherein the method includes: (a) Optionally, a pre-processing step at a temperature ranging from 100° C. to 300° C. at vacuum of 10-5 mbar (10-3 Pa) to 10-8 mbar (10-6 Pa) for 30 minutes to 10 hours, (b) Applying a uniaxial pressure in the range from 1 to 200 MPa, at or around ambient temperature, to obtain a pre-compacted sample, (c) Applying to the pre-compacted of step b) a hydrostatic pressure by Cold Isostatic Pressing, to obtain a pre-compacted sample, (d) Loading the pre-compacted sample from step (c) into a die and submitting the sample to a uniaxial compression in combination with electric field-assisted sintering, under vacuum equal to or higher than 5 Pa. Polycrystalline fluoride ceramics obtained by this method find use in IR devices.
    Type: Application
    Filed: February 8, 2017
    Publication date: September 10, 2020
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Alan LARGETEAU, Mythili PRAKASAM, Inka MANEK-HÖNNINGER
  • Patent number: 10765758
    Abstract: The present invention relates to an optimized in vivo delivery system with endosomolytic agents for nucleic acid of therapeutic interest conjugated to molecules facilitating endocytosis, in particular for use in the treatment of cancer.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: September 8, 2020
    Assignees: ONXEO, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jian-Sheng Sun, Marie Dutreix, Maria Quanz
  • Patent number: 10767276
    Abstract: A method of regenerating a platinum bath by flow reaction, the method comprising the successive steps of: drawing off fluid from the platinum bath by means of a draw-off flow; complexing platinum by mixing together the draw-off flow and a regeneration solution flow containing platinum, mixing taking place in an intensified reactor; and feeding the platinum bath with the mixture resulting from the platinum complexing step, by means of a regenerated bath flow; all of these steps being performed as a continuous flow.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: September 8, 2020
    Assignees: SAFRAN AIRCRAFT ENGINES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Auriane Gengo, Sébastien Elgue, Laurent Prat
  • Patent number: 10767165
    Abstract: The present invention is in the field of stem cells. Particularly, the present invention relates to a reprogramming method for producing induced pluripotent stem cells (iPSC) by transducing somatic differentiated cells with a viral vector expressing ?133p53? isoform, ?133p53? isoform or both ?133p53? and ?133p53? isoforms; to induced pluripotent stem cells as produced by this method; to uses thereof in cell therapy and as an in vitro model for studying various diseases; and to a method for detecting iPSC.
    Type: Grant
    Filed: February 1, 2016
    Date of Patent: September 8, 2020
    Assignee: Centre National de la Recherche Scientifique (CNRS)
    Inventor: Pierre Roux