Patents Assigned to Centre National de la Recherche Scientifique
  • Publication number: 20240154817
    Abstract: A computer-implemented method for memory management in a computer system configured for generating a signature of a binary data message m using a key B of a predetermined lattice-based structure is proposed, which comprises: determining coefficients of a 2×2 signature generation matrix SG, wherein the non-diagonal coefficients of the signature generation matrix SG are complex polynomials with a non-zero imaginary part, and the diagonal coefficients of the signature generation matrix SG are real polynomials; and determining a LDL representation of the signature generation matrix SG according to which SG is represented by a matrix product L.D.
    Type: Application
    Filed: October 5, 2023
    Publication date: May 9, 2024
    Applicants: BULL SAS, UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Etienne MARCATEL, Kevin LEBRET, Philippe ELBAZ-VINCENT
  • Patent number: 11976355
    Abstract: A method for producing a part having improved resistance to oxidation and high temperature-corrosion, includes the formation of an environmental barrier coating on an at least partially ceramic matrix composite material, the environmental barrier coating being formed by direct liquid injection-metal organic chemical vapor deposition.
    Type: Grant
    Filed: September 20, 2021
    Date of Patent: May 7, 2024
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SAPRAN CERAMICS, UNIVERSITE DE BORDEAUX
    Inventors: Arnaud Delehouze, Eric Bouillon, Sylvain Lucien Jacques
  • Patent number: 11976305
    Abstract: The invention relates to recombinant measles virus expressing Lassa virus polypeptides, and concerns in particular immunogenic LASV particles expressed by a measles virus and/or virus like particles (VLPs) that contain proteins of a Lassa virus. These particles are recombinant infectious particles able to replicate in a host after an administration. The invention provides means, in particular nucleic acid constructs, vectors, cells and rescue systems to produce these recombinant infectious particles. The invention also relates to the use of these recombinant infectious particles, in particular under the form of a composition, more particularly in a vaccine formulation, for the treatment or prevention of an infection by Lassa virus.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: May 7, 2024
    Assignees: INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Mathieu Mateo, Sylvain Baize, Frédéric Tangy
  • Patent number: 11976924
    Abstract: Disclosed is a multi-axis atom interferometer system, including a source of cold atoms, a laser source generating a first light pulse configured in such a way as to spatially split the source of cold atoms into a first cloud of atoms propagating along a first trajectory along a first axis and a second cloud of atoms propagating along a second trajectory along a second axis, a second light pulse adapted to spatially deflect the first trajectory along the second axis and simultaneously the second trajectory along the first axis towards a first point and a last light pulse adapted to recombine the at least one part of the first cloud of atoms and the at least one part of the second cloud of atoms at the first point, and a detection system measuring an interferometric phase-shift accumulated between the first light pulse and the last light pulse.
    Type: Grant
    Filed: October 28, 2019
    Date of Patent: May 7, 2024
    Assignees: EXAIL, INSTITUT D'OPTIQUE GRADUATE SCHOOL, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUX
    Inventors: David Brynle Barrett, Pierrick Cheiney, Philippe Bouyer
  • Patent number: 11975075
    Abstract: Disclosed is a process for preparation of heterogeneous monodisperse mixtures of protein conjugates with a defined degree of conjugation (1-8) obtained by using a tri-functional reagent allowing affinity concentration followed by subsequent simultaneous release-functionalization.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: May 7, 2024
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE STRASBOURG, SYNDIVIA
    Inventors: Sergii Kolodych, Oleksandr Koniev, Alain Wagner, Igor Dovgan
  • Patent number: 11974569
    Abstract: The present invention relates to a device for holding human or animal corneal tissue previously removed for photon treatment thereof with electromagnetic radiation, notable in that the holding device comprises: a stack of elements along a longitudinal axis (A-A?) of the device, said stack comprising: a first plate (1) that is transparent to the electromagnetic radiation, a peripheral seal (4) positioned on the first plate (1), the peripheral seal (4) being intended to extend around the corneal tissue (6), a second plate (2) that is transparent to the electromagnetic radiation on the peripheral seal (4), an immobilizing system (51, 52) for immobilizing the stack of elements and able to press the first and second plates (1, 2) firmly against the corneal tissue in order to apply mechanical stress to the anterior and posterior faces of the corneal tissue.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: May 7, 2024
    Assignees: UNIVERSITE JEAN MONNET, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE HOSPITALIER UNIVERSITAIRE, MANUTECH-USD
    Inventors: Philippe Gain, Gilles Thuret, Cyril Mauclair, Clotilde Jumelle, Gregory Egaud
  • Publication number: 20240146065
    Abstract: A method for controlling an electric microgrid comprising an electrical energy consuming element, an electrical energy production element and an electrical energy storage element, the method comprising the steps of extracting parameter values from a source model, the extraction phase being implemented by computer, initializing parameters of a target model with parameter values extracted from the source model, so as to obtain an initialized target model, the initialization phase being implemented by computer, and optimizing, according to a target domain and a target set of tasks, of the parameters of the initialized target model, so as to obtain a target model trained for the control of a target microgrid, the optimization phase being implemented by computer.
    Type: Application
    Filed: December 23, 2021
    Publication date: May 2, 2024
    Applicants: Centre national de la recherche scientifique, Université de Lille, ECOLE POLYTECHNIQUE, TotalEnergies OneTech
    Inventors: Gonzague HENRI, Philippe CORDIER, Tanguy LEVENT, Philippe PREUX, Yves BONNASSIEUX
  • Patent number: 11971310
    Abstract: An optical fibre, for use in the field of distributed measurement of temperature or deformation by optical reflectometry in the frequency domain using the Rayleigh backscattered signal in the fibre, includes a core doped with nanoparticles for example formed from gold particles covered with zirconium oxide, and can be subjected to high temperatures during the measurement. A method for producing the optical fibre includes a step of heat treatment during which the optical fibre is subjected, for a duration of at least one hour, to a heat treatment temperature higher than a maximum temperature to which it will be subjected during a measurement.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: April 30, 2024
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE LILLE
    Inventors: Patrick Bulot, Remy Bernard, Odile Cristini, Monika Bouet, Guillaume Laffont, Marc Douay
  • Patent number: 11971312
    Abstract: A measurement core for measuring nuclear heating, the core extending in a longitudinal direction and having a main plane, includes at least: a first layer of material, forming a first sample; a first thin layer of electrical insulation on the first sample; a thin conductive layer forming a heating electrical resistor on the first layer of electrical insulation; and a second thin layer of electrical insulation on the heating electrical resistor. A calorimetric sensor includes: an outer jacket; a gas contained in the jacket; a measurement core disposed in the jacket; a link for holding the core in the jacket and transferring the heat between the core and the jacket; and temperature measurement capable of measuring the temperature at a hot point, and the temperature at a cold point.
    Type: Grant
    Filed: December 13, 2021
    Date of Patent: April 30, 2024
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Christelle Reynard-Carette, Adrien Volte, Abdallah Lyoussi, Michel Carette
  • Patent number: 11971516
    Abstract: Disclosed is a method for detecting a fluid, including at least one step of: measuring by at least one sensor of a wave propagating in an environment of the wave, in order to obtain at least one measured signal, the wave being particularly a mechanical wave; splitting the measured signal over a plurality of split time intervals with a predefined duration in order to obtain samples of the measured signal; computing the temporal coherence of the samples; and determination of the presence of the fluid using the computed temporal coherence.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: April 30, 2024
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventor: Christophe Voisin
  • Publication number: 20240135991
    Abstract: The electronic circuit performs binary computation operations and comprises word, bit and source lines, and memory cells organized in rows and columns. Each cell includes one pair of memristors and one pair of switches, each memristor being connected to a switch and linked to the same source line during each computation operation, each pair of memristors storing a binary value; the switches being linked to a word line and to a pair of complementary bit lines. The circuit comprises a reading module including: a logic unit for each column, each comprising an input terminal connected to a source line to receive a column value, the logic unit toggling between values, depending on a comparison of the column value with a toggle threshold value; a modification unit for modifying, for at least one logic unit and depending on the computation operation, a difference between the column and threshold values.
    Type: Application
    Filed: October 10, 2023
    Publication date: April 25, 2024
    Applicants: Commissariat à l'énergie atomique et aux énergies alternatives, Centre national de la recherche scientifique, Université d'Aix-Marseille
    Inventors: Mona EZZADEEN, Bastien GIRAUD, Jean-Philippe NOEL, Jean-Michel PORTAL
  • Publication number: 20240133759
    Abstract: A pressure-measuring device including an optical fibre with a thinned portion, a laser, called the heating laser, arranged to emit an optical wave, called the heating wave, into the thinned portion, a measuring means including a sensor that is arranged to measure a backscattered optical wave that is generated by an optical wave, called the interrogation wave, and that originates in the thinned portion of the optical fibre, and a processing unit arranged and/or programmed to measure a pressure of a fluid, preferably a gas, encircling the thinned portion, on the basis of the measurement of the backscattered wave.
    Type: Application
    Filed: April 19, 2022
    Publication date: April 25, 2024
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE FRANCHE-COMTE
    Inventors: Jean-Charles BEUGNOT, Jacques CHRETIEN, Adrien GODET, Kien PHAN HUY, Jérôme SALVI
  • Patent number: 11957435
    Abstract: An acousto-optic imaging method in which light waves and unfocused acoustic waves having various directions of propagation m are emitted in a medium, by spatially modulating the amplitude of the ultrasonic transducers of an array of transducers according to several periodic spatial amplitude modulations j, and the resulting optical signal Smj(t) is captured. For each direction of propagation m, the signals Smj(t) are spatially demodulated in order to determine a signal Sm(t) used to reconstruct the image of the medium.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: April 16, 2024
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, SORBONNE UNIVERSITE, UNIV PARIS XIII PARIS-NORD VILLETANEUSE
    Inventors: François Ramaz, Jean-Luc Gennisson, Jean-Baptiste Laudereau, Clément Dupuy, Jean-Michel Tualle
  • Patent number: 11958804
    Abstract: The present invention relates to the use of 2,5-furanedicarboxylate-based MOFs, such as, MIL-160(AI) metal-organic framework, for separating C6 alkane isomers into linear, mono-branched and di-branched isomers. The present invention also relates to the use of 2,5-furanedicarboxylate-based MOFs, such as, MIL-160(AI) metal-organic framework, preferably in combination with Zeolite 5A for producing higher research octane number gasoline blends. Also within the scope of the invention is a system for separating C6 and C5 alkane isomer mixtures into linear, mono-branched and di-branched fractions.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: April 16, 2024
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUTO POLITÉCNICO DE BRAGANÇA, ÉCOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, ÉCOLE NORMALE SUPÉRIEURE DE PARIS, UNIVERSIDADE DO PORTO
    Inventors: Christian Serre, Farid Nouar, José Silva, Alírio Rodrigues, Pedro Brântuas
  • Publication number: 20240118471
    Abstract: An optical structure comprising at least one stack having a central filter (1) and two sandwiching optical elements (2,3) between which the central filter (1) is interposed, wherein the central filter (1) is in a matrix material. The matrix material being doped with at least one doping agent, the central filter (1) and the two optical elements (2,3) on either side thereof being assembled by bonding layers (4a, 4b) of a material based on the same matrix material as that of the central filter, the optical elements (2,3) on either side of the central filter (1) and the bonding layers (4a, 4b) each having a refractive index equal to that of the material of the central filter or only differing from this refractive index within a range of plus or minus 0.05, preferably within a range of plus or minus 0.02.
    Type: Application
    Filed: October 15, 2020
    Publication date: April 11, 2024
    Applicants: UNIVERSITE CALAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NORMALE SUPERIEURE DE LYON
    Inventors: Stéphane PAROLA, Cesar LOPES, Denis CHATEAU, Frederic CHAPUT
  • Publication number: 20240116923
    Abstract: The present invention relates to a compound of the following general formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as drug for inhibiting ferroptosis.
    Type: Application
    Filed: January 25, 2022
    Publication date: April 11, 2024
    Applicants: Seabelife, Centre National de la Recherche Scientifique (CNRS), Sorbonne Universite, Institut National de la Santé et de la Recherche Médicale (INSERM), Université Claude Bernard Lyon 1, Universite de Rennes 1
    Inventors: Stéphane BACH, Arnaud COMTE, Claire DELEHOUZE, Marie-Thérèse DIMANCHE-BOITREL, Peter GOEKJIAN
  • Publication number: 20240116043
    Abstract: A process for preparing a catalyst material, includes: (a) providing a support material having surface hydroxyl (OH) groups, the support material is ceria (CeO2), zirconia (ZrO2) or a combination, and the support material contains between 0.3 and 2.0 mmol OH groups/g of the support material; (b) reacting the support material with at least one of: (b1) a compound containing at least one alkoxy or phenoxy group bound though its oxygen atom to a metal element from Group 5 (V, Nb, Ta) or Group 6 (Cr, Mo, W); (b2) a compound containing at least one hydrocarbon group bound though a carbon atom to a metal element from Group 5 or 6; (b3) a compound containing at least one hydrocarbon group bound though a carbon atom to a metal element which is copper (Cu); and (c) calcining the product obtained in step (b).
    Type: Application
    Filed: November 29, 2023
    Publication date: April 11, 2024
    Applicants: TOYOTA MOTOR EUROPE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE DE LYON
    Inventors: Phuc Hai NGUYEN, Nicolas MERLE, Marc-Olivier CHARLIN, Kai Chung SZETO, Mostafa TAOUFIK
  • Patent number: 11950919
    Abstract: The invention concerns a method for calibrating a system for real-time measurement of the activity of a cognitive function of a test subject, the method comprising the successive steps of: acquiring electrical signals representative of a neural activity of a test subject; calculating values of markers of the cognitive function activity; generating a plurality of copies of calculated values of markers and adding noise to the generated copies; and, constructing a classifier by machine learning, based on the calculated marker values and noisy copies, the classifier being suitable for measuring the activity of the cognitive function of the test subject by calculating a probability that an electrical signal representative of the neural activity of the test subject results from a predetermined activity state of the cognitive function of the test subject.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: April 9, 2024
    Assignees: Centre National de la Recherche Scientifique (CNRS), Ecole Superieure e Physique Et De Chimie Industrielles De La Ville De Paris, Sorbonne Universite, Paris Sciences et Lettres
    Inventors: François Vialatte, Aldo Mora-Sanchez, Gérard Dreyfus, Antoine Gaume, Alfredo Aram Pulini
  • Patent number: 11956605
    Abstract: The present invention relates to a device (40) for generating a control signal for an electrical system (S), comprising: an analog block (46) connected to the input (42) and to the output (44) of the generation device (40), the analog block (46) comprising an electrical circuit comprising a passive analog component, a measuring component and a generator, a digital block (50) comprising at least one digitally controllable component (70), the passive analog component of the electrical circuit being configured so as to generate the first component of the control signal and the generator of the electrical circuit being configured so as to generate the second component of the control signal, the electrical circuit being configured so as to sum the first and the second component that are generated in order to obtain the control signal.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: April 9, 2024
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT DE RECHERCHE ET DE COORDINATION ACOUSTIQUE/MUSIAUE, SORBONNE UNIVERSITE
    Inventors: Thomas Helie, Tristan Lebrun
  • Patent number: 11945879
    Abstract: The invention relates to multispecific antibody constructs comprising Fab fragments having mutations at the interface of the CH1 and CL domains, said mutations preventing heavy chain/light chain mispairing.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: April 2, 2024
    Assignees: Jean Kadouche, Centre National de la Recherche Scientifique, Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII, University of Lausanne
    Inventors: Jean Kadouche, Jean-Pierre Mach, Olivier Michielin, Vincent Zoete, Justyna Iwaszkiewicz, Martine Cerutti, Sylvie Choblet, Josee Golay