Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.

Abstract: An optical device suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum. The device comprises at least a first coating layer made of a first material, a substrate made of a material different from the first material, and surface texturing forming cavities in the device. A lower layer, disposed directly below the first coating layer, is either a second coating layer made of a material different from the first material or the substrate itself. The lower layer has a predetermined thickness. The optical device has cavities that extend through the first coating layer and are sunk into the lower layer through at least part of its thickness. This structure enhances the optical properties of the device for specific applications in electromagnetic radiation transmission or reflection.

Abstract: Disclosed is a method for producing, in one step, “made to measure” double-stranded DNA vectors from molecular bricks including sequences of interest in the presence of a one and only type IIs restriction enzyme.

Abstract: The invention relates to a device forming a DC voltage bus for a polyphase electrical system (M), comprising voltage legs (A1, A2, A3) each having a plurality of battery cell modules (C1, C2, C3), each module comprising a battery cell or a cluster of battery cells (c1), connected to a DC-to-AC converter (DCAC); said battery cell modules (C1, C2, C3) being connected together in series via the DC-to-AC converter (DCAC); said voltage legs (A1, A2, A3) each being connected to a specific phase leg (B1, B2, B3) for said polyphase electrical system (M), at least one phase leg (B1, B2, B3) having a branch (D1, D2, D3) connected to a rectifier module (R1). The invention also relates to a motor vehicle, a renewable energy generator and a method based on such a system.

Abstract: The present invention relates to a method for producing a colloid comprising functionalised liquid colloidal particles. The invention also relates to such a colloid and to the uses thereof.

Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.

Abstract: This invention relates to a method for preparing a cyclic anhydride such as succinic anhydride and methyl succinic anhydride from an unsaturated carboxylic acid such as acrylic acid or crotonic acid. This method can also be used in the manufacture of food additives, plasticisers, polymers of interest, in particular polyurethanes and elastanes, resins, coatings and pharmaceutical products.

Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.

Abstract: The present invention relates to a device for determining the position of a plurality of objects that are simultaneously trapped by a single laser beam, characterized in that the device comprises:—a laser source for emitting a laser beam, an actuation system for a three-dimensional deflecting of the laser beam between several trapping points,—a microscope objective for focusing the laser beam coming from the actuation system on the trapping points,—a sample chamber including the objects to be trapped on the trapping points,—a light source for lighten the sample chamber, and—a camera for determining the position of each of the trapped objects, said camera being located between the laser source and the actuation system, so that the light emitted by the light source passes successively through the sample chamber, the microscope objective, the actuation system and the camera.

Abstract: The application relates to a method for controlling a microgrid (10) comprising the steps of: maintaining a switching device (60) connecting two busbars (30, 40) of the microgrid (10) and a circuit breaker (20) connecting the microgrid (10) to a utility grid (100) closed, the microgrid (10) being operated in a grid connected mode; measuring (202) a voltage present in the microgrid (10); determining (205) if the measured voltage corresponds to a loss of voltage or a fault in the microgrid (10); and if a the loss of voltage or fault is detected in the microgrid (10), opening (210) the switching device (60), the critical loads being supplied by the battery energy storage system (50) and the circuit breaker (20) remaining closed during (215) at least a fault ride through period.

Abstract: The application relates to a method for protecting a microgrid from a voltage drop or sag occurring in a main grid connected to said microgrid, the method comprising the following steps: a. supplying (105) power to the microgrid through the main grid; b. ascertaining that the voltage drop or sag is occurring in the main grid by executing the following steps: i. measuring (110) an instantaneous output voltage; ii. comparing (130) the measured instantaneous output voltage with a reference instantaneous output voltage; iii. Incrementing (140) a counter when the measured instantaneous output voltage differs from the reference instantaneous output voltage by more than a voltage threshold; and iv. ascertaining (150) that the voltage drop or sag is occurring in the main grid when the counter holds a value that exceeds a counter threshold; and c. disconnecting the microgrid from the main grid when the voltage drop or sag occurring in the main grid has been ascertained.

Abstract: The present invention relates to the long-term preservation of biological material. More specifically, it concerns a preservation container comprising: a biological container for containing biological material, a first shield configured for absorbing gamma-rays, a second shield configured for absorbing ambient neutrons, said second shield surrounding the biological container, the preservation container being of low-radioactivity background materials, and a method for preserving a biological material, comprising: a) providing a biological material in a confinement container, b) providing the preservation container of the invention, c) placing the confinement container containing the biological material into said preservation container, d) storing said preservation container containing the biological material in a room located under a material attenuating cosmic rays and induced particles, said material having a thickness equivalent to 1 m to 7000 m of water, for attenuating cosmic rays.

Abstract: A method for investigating intra- and/or intermolecular interactions involving RNA is provided. The method includes a) synthesizing a RNA/DNA heteroduplex (RDH) comprising a RNA strand of interest paired to a DNA strand; b) binding a first end of the DNA strand and a corresponding first end of the RNA strand to a first element of a nanoscale manipulating device, and a second end of the DNA strand to a second element of the nanoscale manipulating device, leaving a second end of the RNA strand free; c) moving the first and second elements of the manipulating device apart from each other, stretching the DNA strand and causing the RNA strand to peel off the heteroduplex; and d) moving the first and second elements of the nanoscale manipulating device towards each other, allowing the DNA strand to relax and causing the RNA strand to bind again to it. Measurement of a force-displacement relationship during steps c) and d) provides information on intra- and/or intermolecular interactions involving the RNA strand.

Abstract: An electronic chip including a support and connection pillars, each connection pillar including a trunk including an end portion and an intermediate portion coupling the end portion to the support, and including a collar at the junction between the end portion and the intermediate portion.

Abstract: The technique relates to a method for preparing a nanomesh metal membrane 5 transferable on a very wide variety of supports of different types and shapes comprising at least one step of de-alloying 1 a thin layer 6 of a metal alloy deposited on a substrate 7, said method being characterized in that said thin layer 6 has a thickness less than 100 nm, and in that said de-alloying step 1 is carried out by exposing said thin layer 6 to an acid vapor in the gas phase 8, in order to form said nanomesh metal membrane 5.

Abstract: The invention concerns a system and method for reconstructing a physiological signal of an artery/tissue/vein system of an organ in a surface space. Said method is implemented by processing means of a processing unit of a functional imaging analysis system, and comprises a step for reconstructing said physiological signal from a piece of experimental data of a region of interest comprising an elementary volume—called a voxel—of said organ and a surface mesh describing said surface space. The invention differs from known methods in particular in terms of the high accuracy of same and the robustness thereof to noise.

Abstract: The invention provides luminescent lanthanide nanoparticles having simultaneously an improved brightness and an increased lifetime of the excited-state. These nanoparticles comprise terbium ions and ions of a second lanthanide, preferentially europium, and are coated with molecules of chromophore ligand bonded to the surface of the nanoparticle. The ligand is an organic molecule comprising at least one chromophore radical of formula I or of formula II: wherein R is selected from H, CN group or COOH group. The phosphorescence excited-state lifetime is improved by energy transfer from surface terbium ions to core ions of the second lanthanide. The nanoparticle may further comprise a carrier molecule of analytical interest covalently attached to at least one ligand molecule.

Abstract: Microfluidic gas exchange devices may include one or more exchange modules (100), wherein each exchange module includes: a first layer comprising: one or more primary inlets (108); a first capillary network connected to the one or more primary inlets, wherein the first capillary network extends radially outward from at least one of the one or more primary inlets, and wherein the first capillary network includes one or more injection branches (104) and a series of microchannels (106); and one or more primary outlets connected to the first capillary network; and a second layer that includes a semipermeable membrane.

Abstract: The present invention is in the field of oncology, and more particularly of cancer stem cells. It relates to a method for producing cancer stem cells based on overexpression of ?133p53? isoform, ?133p53? isoform, or both ?133p53? and ?133p53? isoforms; a method for predicting the risk that treatment with a chemotherapeutic anti-cancer agent induces cancer stem cells in a subject suffering from cancer from a cancer sample of said subject, based on detection of an increase in ?133p53? isoform, ?133p53? isoform, or both ?133p53? and ?133p53? isoforms following chemotherapeutic anti-cancer treatment; to therapeutic uses of a combination of chemotherapeutic anti-cancer agent and an agent reducing ?133p53? isoform, ?133p53? isoform, or both ?133p53? and ?133p53? isoforms expression; and also to screening methods for anti-cancer stem cells agents.

Abstract: The invention relates to a system and an implementation method for pumping a fluid, the system comprising: a pump comprising a flexible membrane which has two opposing surfaces, the membrane comprising a spatially rotating permanent magnetization structure, a rigid support means to which at least a portion of the lower surface of the membrane is attached, a source of a magnetic field which is capable of generating a magnetic drive field at the location of the membrane, the magnetic drive field having a substantially homogeneous orientation.