Patents Assigned to Centre National de la Recherche Scientifique (Cnrs)
  • Publication number: 20180171134
    Abstract: The invention relates to a process for reducing the defectivity of a block copolymer (BCP1) film, the lower surface of which is in contact with a preneutralized surface (N) of a substrate (S) and the upper surface of which is covered by an upper surface neutralization layer (TC) in order to make it possible to obtain an orientation of the nanodomains of the block copolymer (BCP1) perpendicularly to the two lower and upper interfaces, where the upper surface neutralization layer (TC) employed to cover the upper surface of the block copolymer (BCP1) film comprises a second block copolymer (BCP2).
    Type: Application
    Filed: May 26, 2016
    Publication date: June 21, 2018
    Applicants: ARKEMA FRANCE, INSTITUT POLYTECHNIQUE DE BORDEAUX, UNIVERSITE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Xavier Chevalier, Celia NICOLET, Christophe NAVARRO, Georges HADZIIOANNOU
  • Publication number: 20180172974
    Abstract: The invention relates to an optical device for measuring the position of an object along a first axis, the object being subjected to light radiations emitted by a light source.
    Type: Application
    Filed: February 15, 2018
    Publication date: June 21, 2018
    Applicants: Paris Sciences Et Lettres - Quartier Latin, Centre National de la Recherche Scientifique (CNRS), Universite Pierre Et Marie Curie (Paris 6), Universite Paris Diderot Paris 7
    Inventors: Vincent Croquette, Jean-François Allemand, Thibault Vielle
  • Publication number: 20180172640
    Abstract: The invention concerns a Thickness Shear Mode (TSM) biosensor (1) which comprises an ex vivo living skin explant (2), the skin explant (2) comprising at least one of the skin layers among: hypodermis, dermis (2A), epidermis (2B) and the stratum corneum (2C), a TSM transducer (3) which comprises: an AT cut quartz resonator 3C which has two opposite exterior surfaces (3A,3B), and two conducting electrodes (4A, 4B), each conducting electrode being deposited on one of the two exterior surfaces (3A,3B), the TSM transducer (3) allowing to determine micro rheological characteristics of the living skin explant (2) by piezoelectric transducing using shear waves, the TSM transducer (3) presenting: measuring means (30), monitoring and calculating means (31) which monitor an evolution in time of an electrical response of the living skin explant (2), and which calculate in time, from the electrical response, micro rheological characteristics of the living skin explant (2), a bottom surface of the skin explant (2) being in
    Type: Application
    Filed: June 8, 2016
    Publication date: June 21, 2018
    Applicants: Centre National de la Recherche Scientifique (CNRS ), Universite Cergy-Pontoise, Centre de Recherches Biologiques et D'Experimentations Cutanees
    Inventors: Régis Besse, Jean-Yves Le Huerou, Stéphane Serfaty, Elian Lati
  • Patent number: 9999647
    Abstract: The invention relates to a method for obtaining a composition from a plant extract, to assist in the treatment or prevention of disorders or diseases related to neovascularisation.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: June 19, 2018
    Assignees: Ethnodyne, Centre National De La Recherche Scientifique (CNRS)
    Inventors: Chérif Rabhi, Léon Cariel, Jamal Ouanzzani, Guillaume Arcile
  • Patent number: 9995929
    Abstract: The invention concerns a method for tuning at a targeted resonance wavelength at least one micro and/or nanophotonic resonator, the resonator having dimensions defining resonance wavelength of said resonator, the resonator being immersed in a fluid containing ions so that the resonator is surrounded by said fluid, wherein the method comprises a step of injecting light, having a light wavelength equal to the resonance wavelength, into the resonator, so that the injected light resonates within the resonator and triggers a photo-electrochemical etching process enabled by the surrounding fluid containing ions, said etching process being enhanced by the optical resonance which amplifies light intensity in the photonic resonator, the etching decreasing dimensions of the photonic resonator, hereby lowering and tuning the resonance wavelength of the photonic resonator.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: June 12, 2018
    Assignees: Universite Paris Diderot Paris 7, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Ivan Favero, Christopher Baker, Eduardo Gil Santos
  • Publication number: 20180156819
    Abstract: The present Inventors demonstrated that the RelB subunit of NF?B plays a crucial role in promoting cell migration. More precisely, they identified that this pro-migratory activity is mediated by the activation of the NF?B pathway through RelB phosphorylation at serine 472. In a first aspect, the present invention proposes to monitor the activation of the NF?B pathway by following the phosphorylation status of said serine. Also, the present invention discloses methods and kits for prognosing the evolution of a disease involving cell migration in a subject—treated or not—suffering thereof, based on the detection of said RelB-S472 phosphorylation.
    Type: Application
    Filed: November 20, 2017
    Publication date: June 7, 2018
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS ), UNIVERSITE PARIS DESCARTES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M EDICALE (INSERM)
    Inventors: Veronique BAUD, Katy BILLOT
  • Patent number: 9989464
    Abstract: A non-destructive method for detecting charged particles, includes measuring a reference value of at least one physical parameter of an ion cloud confined in an ion trap; performing an injection of a sample in the ion cloud confined in the ion trap, the sample crossing the ion cloud and getting out the ion cloud without being trapped inside the ion trap; measuring a first experimental value of the at least one physical parameter of the ion cloud; and comparing the first experimental value with the reference value in order to determine the presence of at least one charged particle in the sample, or the absence of any charged particle in the sample.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: June 5, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'AIX-MARSEILLE
    Inventors: Caroline Antoinette Madeleine Champenois, Laurent Hilico, Christophe Michel René Jouvet, Jofre Pedregosa Gutierrez, Martina Knoop, Claude Dedonder-Lardeux
  • Publication number: 20180148336
    Abstract: The present invention relates to a process for the preparation of a boron phosphide, more specifically BP and/or B12P2, comprising the mechanochemical reaction of boron phosphate (BPO4) with at least one alkaline earth metal (EA). In particular, the process of the invention allows for the selective preparation of either BP or B12P2 with more than 95% purity, through the reduction of boron phosphate (BPO4) with at least one alkaline earth metal (EA) according to reaction (1) for BP and according to reaction (2) for B12P2: BPO4+4 EA->BP+4 EA(O) (1) 2BPO4+5 (EA)B2+3 EA->B12P2+8 EA(O) (2). The present invention further relates to boron phosphide powders, in particular BP or B12P2 powders, of nanometric or micrometric size.
    Type: Application
    Filed: April 8, 2016
    Publication date: May 31, 2018
    Applicants: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIV PARIS XIII PARIS-NORD VILLETANEUSE
    Inventors: Yann LE GODEC, Vladimir A. MUKHANOV, Vladimir L. SOLOZHENKO, Petr S. SOKOLOV, Dominique VREL
  • Publication number: 20180148666
    Abstract: The invention relates to a vetiveryl ester comprising at least 0.5 weight percent of secondary alcohol compounds with respect to the total weight of the vetiveryl ester and to a process for the preparation a vetiveryl ester, the process comprising: providing a vetiver oil, at least one enzyme preparation and at least one acylating compound; and allowing sufficient time for the enzyme preparation to esterify the alcohol compounds of the vetiver oil with the acylating compound. The invention also relates to a vetiveryl ester obtainable by the above process, a fragrance composition comprising an above-mentioned vetiveryl ester and the use of an above-mentioned vetiveryl ester for the preparation of a perfumed product.
    Type: Application
    Filed: May 30, 2016
    Publication date: May 31, 2018
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, UNIVERSITÉ DE NICE-SOPHIA ANTIPOLIS
    Inventors: Sylvain Antoniotti, Jean-Jacques Filippi, Irene Notar Francesco, Jade Ramilijaona
  • Publication number: 20180147389
    Abstract: The present invention relates to a single-lumen vascular catheter (1) to be inserted into a blood flow channel for the injection of a product by the venous or arterial route, comprising a tube (2) having a hollow longitudinal body with a lumen (3), the lumen (3) extending along the full length of the tube (2) and being intended to permit the injection of a given volume (4) of product at a prescribed flow rate the tube (2) having lateral orifices (5) which are of substantially identical size and are arranged in the longitudinal body substantially symmetrically about the longitudinal axis, near a distal end (6) of the tube (2), an end surface (7) at the distal end (6) of the tube (2) reducing a total surface area of the lumen (3) starting from the distal end (6) of the tube (2).
    Type: Application
    Filed: May 20, 2016
    Publication date: May 31, 2018
    Applicants: Universite Paris Diderot Paris 7, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Gérard Guiffant, Jacques Merckx, Patrice Flaud
  • Patent number: 9981862
    Abstract: The invention relates to a method for the decontamination of contaminated liquid, as well as a reactor for implementing a decontamination method. The method comprises a step of mixing the contaminated liquid under stirring with at least one persulphate ion with the exception of ammonium persulphate, and at least iron, an iron atom or an iron ion in its ferrous or ferric form at a concentration between 50 ?M and 600 ?M, preferably between 100 ?M and 400 ?M, a second step in which the mixture obtained is subjected for a sufficient time to at least one UV/visible irradiation having a narrow wavelength spectrum comprised between 153 nm and 560 nm.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: May 29, 2018
    Assignees: UNIVERSITE D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Stephane Barbati, Serge Chiron, Moussa Mahdi Ahmed, Hichem Bouzidi
  • Publication number: 20180141009
    Abstract: The invention relates to a process for manufacturing a laminated material (S) comprising a fibrillated cellulose layer, characterized in that it comprises the following steps: (a) depositing a suspension (1) of fibrillated cellulose on a filtration membrane (2) and draining the suspension through that membrane so as to form a wet layer of fibrillated cellulose (A) having a dryness, that is to say a ratio between the mass of dry matter and the total mass of the fibrillated cellulose layer, of between 5% and 18%; (b) transferring the wet layer (A) under pressure to an at least partially hydrophilic surface of a substrate (B), so as to form the laminated material (S); (c) drying the laminated material. The invention also relates to a device for implementing the process.
    Type: Application
    Filed: April 27, 2016
    Publication date: May 24, 2018
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), CENTRE TECHNIQUE DU PAPIER
    Inventors: David GUERIN, Yahia RHARBI, Patrick HUBER, Valérie MEYER
  • Publication number: 20180127350
    Abstract: The present invention relates to a process for preparing polyols. In particular, the present invention relates to the preparation, in a single step, of polyols by a process involving a hydrohydroxymethylation reaction starting from a composition A comprising one or more compounds of formula (I).
    Type: Application
    Filed: June 15, 2016
    Publication date: May 10, 2018
    Applicants: PIVERT S.A.S., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'ARTOIS
    Inventors: Frederic HAPIOT, Eric MONFLIER, Theodore VANBESIEN
  • Patent number: 9963669
    Abstract: The invention concerns a facility for coupling a bioreactor for culturing bio-organisms, in dynamic mode, with at least one device for physicochemically analyzing a fluid from this bioreactor or collecting samples of this fluid, the device being equipped with a pump and an injector, the bioreactor being equipped with means for supplying culture medium and xenobiotic(s). The facility is remarkable in that the bioreactor is connected to a closed perfusion loop provided with a pump, fitted with a sampling loop and in that the facility comprises: a device for injecting a cleaning product into said sampling loop, two six-way valves, the first valve being connected to the closed perfusion loop, to the sampling loop and to a cleaning loop, the second valve being connected to the cleaning loop and an injection loop that connects the injector to at least one of the devices.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: May 8, 2018
    Assignees: Universite Technologie De Compiegne—UTC, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Eric Leclerc, Patrick Paullier, Franck Merlier
  • Publication number: 20180118900
    Abstract: The invention relates to a material comprising: a first crosslinked polymer forming a network, and a second linear polymer comprising n monomers, each of the monomers having the following formula I: (I), where m varies from 0 to 4, R is selected from hydrogen, an ethyl group and an alkyl group, and n is a non-zero natural integer, said material being such that it forms a semi-interpenetrating network wherein the second linear polymer is entangled in the network of the first polymer.
    Type: Application
    Filed: April 22, 2016
    Publication date: May 3, 2018
    Applicants: AVRIL, Centre National de la Recherche Scientifique (CNRS ), Université Paris-Est Créteil Val de Marne (UPEC)
    Inventors: France Thevenieau, Carine Mangeon, Estelle Renard, Valérie Langlois
  • Publication number: 20180110820
    Abstract: The invention relates to the use of a composition from a plant extract of Withania somnifera, to prevent, treat of delay the progression of ?-synuclemopathies, including Parkinson disease.
    Type: Application
    Filed: April 13, 2015
    Publication date: April 26, 2018
    Applicants: Ethnodyne, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Chérif Rabhi, Léon Cariel, Jamal Ouanzzani, Guillaume Arcile
  • Publication number: 20180105872
    Abstract: The present invention relates to a method of preparation of substrates for nucleic acid sequencing reactions. More specifically, the present invention provides a new method of preparing hairpins using force-induced strand invasion. Hairpins prepared by this method and methods of nucleic acid analysis using these hairpins are also part of the present invention.
    Type: Application
    Filed: May 4, 2016
    Publication date: April 19, 2018
    Applicants: PARIS SCIENCES ET LETTRES-QUARTIER LATIN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), UNIVERSITE PARIS DIDEROT PARIS 7
    Inventors: Vincent CROQUETTE, Jimmy OUELLET
  • Patent number: 9944669
    Abstract: The present invention relates to hybrid fumarate-CO-releasing molecules capable of increasing heme oxygenase-1 (HO-1) activity and HO-1 protein expression and simultaneously releasing CO, their synthesis and their use in therapeutic applications, in particular their use in the treatment of inflammatory or cardiovascular diseases.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: April 17, 2018
    Assignees: UNIVERSITE PARIS EST CRETEIL VAL DE MARNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Roberto Motterlini, Roberta Foresti, Thierry Martens, Michael Rivard
  • Publication number: 20180100887
    Abstract: Method of contactless measurement of the conductivity of semiconductors, said method being implemented by: a first assembly comprising a signal emission/reception system —a second assembly comprising at least one semi-conducting target and an inductor element, —a third assembly, said method comprising at least the following steps: a) the first assembly emits a multifrequency signal, b) the second assembly reflects or transmits at least one part of the multifrequency signal emitted, c) the first assembly receives the reflected multifrequency signal reflected by the second assembly, d) the third assembly calculates the coefficient of reflection or of transmission of the emitted signal, e) the third assembly provides the conductivity of the semiconducting target.
    Type: Application
    Filed: April 7, 2016
    Publication date: April 12, 2018
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, UNIVERSITE PARIS-SUD, ECOLE SUPERIEURE D'ELECTRICITE
    Inventors: Denis Mencaraglia, Yann Le Bihan, Florent Loete
  • Patent number: 9938456
    Abstract: This deals with a luminescent salt comprising a metal cluster anion and an organic cation, wherein the metal cluster anion comprises a metal cluster with at least two metal atoms, and ligands, the metal atoms being chosen from the group consisting of molybdenum, rhenium, tungsten, thallium, niobium, and mixtures thereof, wherein the organic cation comprises a cationic head substituted by at least one substituent including a polymerizable functional group. It also deals with a polymeric material comprising a polymer matrix which has polymerized with this luminescent salt.
    Type: Grant
    Filed: January 15, 2014
    Date of Patent: April 10, 2018
    Assignees: Universite de Rennes 1, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Yann Molard, Maria De Los Angeles Amela-cortes, Stephane Cordier