Patents Assigned to Centre National de la Recherche Scientifiques (C.N.R.S.)
  • Method for preparing a water-compatible composition of metal oxide nanocrystals and the water-compatible composition obtained
    Patent number: 9162900
    Abstract: A method for preparing a composition of metal oxide nanocrystals from at least one organometallic precursor in an aprotic solvent in the presence of at least one PEG ligand including a carbon chain having at least one end functionalized by a coordinating group containing at least one heteroatom, and at least one [—OCH2CH2]n, group, such that it is soluble in both the aprotic solvent medium and in water. The resulting water-compatible and organocompatible composition of metal oxide nanocrystals is also described.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: October 20, 2015
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Myrtil Kahn, Fabienne Gauffre Guirardel, Javier Rubio-Garcia, Christophe Mingotaud, Bruno Chaudret
  • Methods for diagnosing skin diseases
    Patent number: 9157119
    Abstract: The present invention relates to methods for diagnosing cornification disorders and metabolic diseases. More specifically, the present invention relates to an in vitro method for diagnosing and/or predicting a cornification disorder in a subject, comprising determining the presence or the absence of a genetic variation in the Patatin-like phospholipase domain-containing protein 1 (PNPLA1) gene sequence in a biological sample from said subject, as compared with the PNPLA1 gene sequence of a healthy non-carrier subject, wherein the presence of said genetic variation indicates that said subject suffers from or is at risk of suffering from said cornification disorder. The method according to the invention allows for example diagnosing ichthyosis in dogs of the Golden Retriever breed.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: October 13, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE DE RENNES 1
    Inventors: Catherine Andre, Sandrine Planchais, Eric Guaguere
  • Polyurethane synthesis by means of self-condensation
    Patent number: 9133305
    Abstract: The present invention relates to a compound with the following formula (I) where: R1 is particularly a straight or branched alkyl group, a is a single or double bond; R2 is particularly a hydrogen atom; R3 and R5 are a hydrogen atom when a is a single bond, and absent when a is a double bond; R4 is a hydrogen atom or an ORb group, where Rb is a hydrogen atom or an alkyl group including 1 to 12 atoms of carbon, and A1 is a divalent alkylene radical.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: September 15, 2015
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Henri Cramail, Aurelie Boyer, Dnyaneshwar Palaskar, Eric Cloutet, Carine Alfos
  • NON-THERMOSENSITIVE MEDIUM FOR ANALYZING SPECIES IN A CHANNEL AND FOR MINIMIZING ABSORPTION AND/OR ELECTROOSOMOSIC PHENOMENA
    Publication number: 20150253285
    Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.
    Type: Application
    Filed: February 11, 2015
    Publication date: September 10, 2015
    Applicants: INSTITUTE CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Jean-Louis VIOVY, Valessa Barbier
  • Method for preparing a silica grafted with an organosilicon compound
    Patent number: 9127026
    Abstract: The present invention relates to a method for preparing a silica grafted with an organosilicon compound, to a grafted silica obtained according to said method and to the use thereof in compositions of silicone crosslinkable into an elastomer.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: September 8, 2015
    Assignees: BLUESTAR SILICONES FRANCE SAS, UNIVERSITE MONTPELLIER 2, SCIENCES ET TECHNIQUES, ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE MMONTPELLIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: David Mariot, François Ganachaud
  • Artificial retina that includes a photovoltaic material layer including a titanium dioxide semiconductor
    Patent number: 9125734
    Abstract: An artificial retina that includes: (i) a substrate; (ii) a first layer, placed onto said substrate and including photovoltaic material portions separated by at least one insulating material portion; and (iii) a second layer, placed onto said first layer and including conductive material portions separated by at least one insulating material portion. In said artificial retina, the photovoltaic material includes a titanium dioxide semiconductor.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: September 8, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE DE STRASBOURG
    Inventors: Nicolas Keller, Pierre Bernhardt, Michel Roux, Anne Robe, Shankar Muthukonda Venkatakrishnan, Serge Picaud, Marc J. Ledoux, Valerie Keller-Spitzer, Thomas Cottineau
  • METHOD FOR PREPARING A COMPOSITION COMPRISING COLOURED SILICATE MINERAL PARTICLES AND A COMPOSITION COMPRISING COLOURED SILICATE MINERAL PARTICLES
    Publication number: 20150240083
    Abstract: A method for preparing a composition including silicate mineral particles that have colouring properties in which a talcose composition, including phyllosilicate mineral particles chosen from the group formed: from the particles having the chemical formula: ((SixGe1-x)4 M3O10 (OH)2, the particles having at least one interlayer space and having the chemical formula: (SixGe1-x)4 M3-? O10 (OH)2, (M?m+)??.nH2O: —M having the formula Mgy(1)Coy(2)Zny(3)Cuy(4)Mny(5) Fey(6)Niy(7)Cry(8); —M?m+ designating at least one interlayer cation, the silicate mineral particles having a thickness of less than 100 nm and of which the largest dimension is less than 10 ???, is brought into contact with a dye solution, including dye cations, of at least one element chosen from the transition metals, the lanthanides and the actinides. The composition obtained by this method is also described.
    Type: Application
    Filed: September 20, 2013
    Publication date: August 27, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S.), UNIVERSITE PAUL SABATIER TOULOUSE III
    Inventors: Francois Martin, Emmanuel Gardes, Pierre Micoud, Christophe Le Roux
  • Bicarbonate precursors, method for preparing same and uses thereof
    Patent number: 9115111
    Abstract: The present invention concerns a compound of following formula (I): where: R1 is H or an alkyl group, A1 is a divalent straight-chain or branched alkylene radical, and A2 is a —O-A4-O— radical, A4 is a divalent straight-chain or branched alkylene radical.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: August 25, 2015
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Henri Cramail, Aurelie Boyer, Eric Cloutet, Benoit Gadenne, Alfos Carine
  • Functionalisable Polysilylated Organosilane Precursors
    Publication number: 20150232489
    Abstract: The present invention concerns a funtionalisable polysilylated organosilane precursors with formula (I): in which: Z1 represents a moiety with formula (a) and Z2 represents a moiety with formula (b) Z1 and Z2 simultaneously represent a moiety chosen from the moieties R7R8Si(OH), R9Si(OH)2, Si(OH)3, R7R8SiO1/2, R9SiO or Si03/2; U represents a moiety chosen from the moieties with formulas (U1), (U2), (U3), (U4), (U5), (U6), (U7), (U8).
    Type: Application
    Filed: July 8, 2013
    Publication date: August 20, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), ECOLE NATIONALE SUPERIEURE DE CHIMIE DE DE MONTPEILLIER, UNIVERSITE MONTPELLIER 2, SCIENCES ET TECHNIQUES
    Inventors: Michel Wong Chi Man, Xavier Cattoen, Nirmalya Moitra, Kristyna Burglova, Jana Hodacova
  • Method for functionalizing natural fatty substances
    Patent number: 9108908
    Abstract: The invention relates to a method for functionalizing natural fatty substances: According to said method, plant oils including at least two unsaturations and the derivatives thereof, fatty acids including at least one unsaturated compound and the derivatives thereof, and mixtures of same, are reacted with a thiol derivative of formula (I), at a temperature of between 0° C. and the temperature of total degradation of the natural fatty substance and in the presence of a thermal initiator compound or a redox initiator, or by UV radiation, or by UV radiation and in the presence of a photoinitiator. The invention also relates to the resulting functionalized fatty substances and to the use thereof for the preparation of polymers. The invention further relates to a method for preparing polymers from at least one functionalized fatty substance obtained by said functionalization method.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: August 18, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER, UNIVERSITE MONTPELLIER 2, SCIENCES ET TECHNIQUES
    Inventors: Sylvain Caillol, Bernard Boutevin, Myriam Desroches
  • Method for preparing furfural
    Patent number: 9090580
    Abstract: The invention relates to a method for preparing furfural by reacting pentose in water and in the presence of carboxylic acid and of a heterogeneous acid catalyst, the method being conducted in an aqueous solution of carboxylic acid as a reaction medium. The present invention also relates to the preparation of furfural by reaction of pentose in water and in the presence of carboxylic acid and of a heterogeneous acid catalyst. The invention also relates to an aqueous solution of carboxylic acid rich in furfural.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: July 28, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE CLAUDE BERNARD LYON I
    Inventors: Nadine Essayem, Rodrigo Lopez De Souza, Franck Rataboul, Aude-Claire Doiseau
  • 1,4-naphthoquinones derivatives and therapeutic use thereof
    Patent number: 9090549
    Abstract: 1,4 naphthoquinones derivatives, of formula (I) wherein A is selected from the following rings: their preparation and their application as antimalarial agents
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: July 28, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), REPRECHT-KARLS-UNIVERSITAT HEIDELBERG
    Inventors: Elisabeth Davioud-Charvet, Tobias Muller, Holger Bauer, R. Heiner Schirmer
  • Dehydration of methanol to dimethyl ether using catalysts based on a zeolite supported on silicon carbide
    Patent number: 9073837
    Abstract: A process for the preparation of dimethyl ether by catalytic dehydration of methanol, in which there is used a catalyst based on a zeolite immobilized on a silicon carbide support, for example a zeolite of type ZSM-5 supported on silicon carbide extrudates or on a silicon carbide cellular foam.
    Type: Grant
    Filed: December 7, 2007
    Date of Patent: July 7, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE LOUIS PASTEUR
    Inventors: Svetlana Ivanova, Estelle Vanhaecke, Suzanne Libs, Benoit Louis, Cuong Pham-Huu, Marc Jacques Marie Ledoux
  • Method and device for measuring the angular position of a rectilinear contrasting edge of an object, and system for fixation and tracking a target comprising at least one such contrasting edge
    Patent number: 9074872
    Abstract: The present invention relates to a method for measuring the angular position of a contrasting edge of an object having a luminance transition zone which is substantially rectilinear in a given direction and separates two regions of different luminances. This method comprises the functional steps of: —carrying out, in a transverse direction different from the given direction, an amplitude modulation of the signals delivered by a first and a second optical sensor; and —calculating an output signal (Yout(t)) starting from the signals delivered by the first and the second optical sensors (D1, D2) as a function of the angular position of the luminance transition zone. Device and set of devices for measuring the angular position of a contrasting edge and steering aid system for fixation and tracking a target comprising at least one such contrasting edge.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: July 7, 2015
    Assignees: UNIVERSITE D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Lubin Kerhuel, Nicolas Franceschini, Stephane Viollet
  • Immunoadjuvant compounds and uses thereof
    Patent number: 9061066
    Abstract: Cyclic beta glucan compounds function as an immunoadjuvant when administered prior to, concommitantly with, or subsequent to the administration of one or more antigens to a subject. These adjuvant compounds may be effectively used as dendritic cell activating molecules.
    Type: Grant
    Filed: June 6, 2011
    Date of Patent: June 23, 2015
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (C.N.R.S.), Universite d'Aix-Marseille
    Inventors: Jean-Pierre Gorvel, Jacques Banchereau, Anna Martirosyan, Eynav Klechevsky, Sangkon Oh
  • PROCESS FOR CREATING CARBON-CARBON BONDS USING CARBONYL COMPOUNDS
    Publication number: 20150166464
    Abstract: The present invention concerns a process for preparing a compound of formula (I) by reaction between a compound of formula (II) and a compound of formula (III) in the presence of a copper-containing catalyst, a ligand and base. The invention also concerns the implementing of this process for the preparation of building blocks to prepare molecules of interest in particular in the pharmaceutical, agro-chemical fields, etc.
    Type: Application
    Filed: June 6, 2013
    Publication date: June 18, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S.), UNIVERSITE MONTPELLIER 2, SCIENCES ET TECHNIQUES, ECOLE NATIONALE SUPERIEURE DE CHIME DE MONTPELLIER
    Inventors: Marc Taillefer, Florian Monnier, Anis Tlili, Grégory Danoun
  • Compounds and methods for preventing or treating a viral infection
    Patent number: 9056071
    Abstract: A compound is provided which has a structure I: A-B-C and a method for administering the compound is also provided for use in the prophylaxis and/or treatment of a viral infection, and in particular for preventing and/or inhibiting viral replication, in which A is a quinoline or quinoline-like group, B is a sole amino acid or a peptide or polypeptide having a given amino acid sequence, and C is an O-phenoxy group. According to one embodiment, the compound is a protease inhibitor such as a caspase inhibitor, and the inhibitor can be Q-VD-OPh (N-(2-(quinolyl)valylaspartyl-(2,6-difluorophenoxy)methyl ketone), optionally in an O-methylated form. Antiviral compositions and kits are also provided.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: June 16, 2015
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), INSTITUT PASTEUR, UNIVERSITÉ PARIS-SUD
    Inventors: Jerome Estaquier, Mireille Laforge, Anna Senik
  • Fluoride Ion Electrochemical Cell
    Publication number: 20150155598
    Abstract: Electrochemical cells of the present invention are versatile and include primary and secondary cells useful for a range of important applications including use in portable electronic devices. Electrochemical cells of the present invention also exhibit enhanced safety and stability relative to conventional state of the art primary lithium batteries and lithium ion secondary batteries. For example, electrochemical cells of the present invention include secondary electrochemical cells using anion charge carriers capable of accommodation by positive and negative electrodes comprising anion host materials, which entirely eliminate the need for metallic lithium or dissolved lithium ion in these systems.
    Type: Application
    Filed: November 21, 2014
    Publication date: June 4, 2015
    Applicants: California Institute of Technology, Centre National De La Recherche Scientifique (C.N.R.S.)
    Inventor: Rachid YAZAMI
  • Resins of the phenoplast type obtained from phenolic compounds and from macromolecular hardeners bearing aldehyde functions
    Patent number: 9040650
    Abstract: A method for preparing a formaldehyde-free phenolic plastic resin, includes a step of preparing a hardener via careful oxidation of a polyol and a step of reacting the hardener with phenolic compounds.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: May 26, 2015
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER
    Inventors: Sylvain Caillol, Bernard Boutevin, Ghislain David, Carine Burguiere
  • Octapeptide compounds and therapeutic use thereof
    Patent number: 9040482
    Abstract: The present invention relates to novel octapeptide compounds of general formula (I), R-AA1-cyclo(AA2-Tyr3-D-Trp4-AA5-Val6-Cys7)-Thr8-NH2??(I) As these products have a good affinity for certain sub-types of somatostatin receptors, they are particularly useful for treating the pathological states or diseases in which one (or more) of the somatostatin receptors is (are) involved. The invention also relates to pharmaceutical compositions containing said products and their use for the preparation of a medicament.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: May 26, 2015
    Assignees: IPSEN PHARMA S.A.S., COMMISSARIAT A L'ENERGIE ATOMIQUE (C.E.A.), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
    Inventors: Jean-Christophe Cintrat, Melinda Ligeti, Bernard Rousseau, Franck Artzner, Christophe Tarabout, Marie-Thérèse Paternostre, Nicolas Fay, Roland Cherif-Cheikh, Céline Valery