Abstract: A method for analyzing the respiratory activity of a patient includes steps for acquiring at least one respiratory activity signal including at least one elementary signal corresponding to a respiratory cycle, the general form of which may be expressed by x(t)=x0+x1 cos(?(t)), wherein ?(t) is the phase of the elementary signal, and for analyzing the respiratory activity signal.
Type:
Grant
Filed:
April 28, 2011
Date of Patent:
May 16, 2017
Assignee:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)
Abstract: A storage device, comprising at least one spintronic element suitable for representing a state among at least n states associated with the spintronic element, n>1, characterized in that each of the n states is associated with at least one characteristic of a group of magnetic skyrmions in the spintronic element, and in that said characteristic associated with a state n oi is different from said characteristic associated with a state n oj when the states n oi and n oj are two different states among the n states.
Type:
Grant
Filed:
August 1, 2014
Date of Patent:
May 16, 2017
Assignees:
THALES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITÉ PARIS-SUD
Inventors:
Vincent Cros, Albert Fert, Joao Sampaio, Pierre Seneor
Abstract: The present invention relates to novel mu-conotoxin peptides, biologically active fragments thereof, combinations thereof and/or variants thereof. The invention also relates to their use in pharmaceutical composition for the treatment or prevention of pain, and their use in the preparation of an anesthetic.
Type:
Grant
Filed:
January 11, 2013
Date of Patent:
May 9, 2017
Assignee:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
Inventors:
Philippe Favreau, Evelyne Benoit, Jordi Molgo, Reto Stöcklin
Abstract: The invention relates to aqueous dispersions, comprising particles based on a magnetic iron oxide with dimensions of ?20 nm, the surface of which is modified by the grafting of aminated groups R with a covalent bonding to the surface of said particles, wherein the isoelectronic point of particles with such a modified surface is ?10. The invention further relates to a method for production of said aqueous suspensions and a method for modification of the surface of the particles present in said dispersions, in particular, by the immobilisation of polysaccharides such as dextrans, particularly for the formulation of magnetic compositions which may be administered in vivo and in particular for the formulation of injectable compositions of contrast agents for MRI.
Type:
Grant
Filed:
May 13, 2004
Date of Patent:
April 25, 2017
Assignee:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)
Inventors:
Etienne Duguet, Stéphane Mornet, Joseph Portier
Abstract: The present invention relates to the use of polymers of the following formula (I): wherein: A1i represents a radical alkylene divalent comprising from 2 to 20 carbon atoms; A2i represents a radical alkylene divalent comprising from 2 to 20 carbon atoms; X1i is chosen from the group consisting of: —S—, —CH2— and a bond; Y represents H, a phenyl group or an alkyl group comprising from 1 to 10 carbon atoms; i represents an integer varying from 1 to n; n represents an integer comprised from 2 to 1,000; provided that the total number of carbon atoms of the radicals A2i, X1i et A1i is greater than or equal to 8; as additives in a polymeric matrix chosen from the group consisting of matrices of polyester, poly(vinyl chloride), polyurethane, polyamide, poly(alkyl acrylate), poly(alkyl methacrylate), polystyrene and polyolefin, said polymer of formula (I) being different from poly(ricinoleic acid).
Type:
Grant
Filed:
April 8, 2014
Date of Patent:
April 25, 2017
Assignees:
Université de Bordeaux, Institut Des Corps Gras Etudes Et Recherches Technigues—Iterg, Centre National de la Recherche Scientifique (C.N.R.S), Institut Polytechnique de Bordeaux
Inventors:
Henri Cramail, Thomas Lebarbe, Benoit Gadenne, Carine Alfos
Abstract: The present invention relates to a method for diagnosing a neurodegenerative disease in a subject, wherein the level of each of at least two catecholamines is measured in a sample of biological fluid from said subject.
Type:
Grant
Filed:
September 17, 2012
Date of Patent:
March 28, 2017
Assignees:
Centre National De La Recherche Scientifique (C.N.R.S), Universite Paris-Sud 11
Inventors:
Myriam Taverna, Romain Verpillot, Markus Otto, Hans Klafki
Abstract: Provided are methods, systems and devices for thermodynamically evaluating electrochemical systems and components thereof, including electrochemical cells such as batteries. The present systems and methods are capable of monitoring selected electrochemical cell conditions, such as temperature, open circuit voltage and/or composition, and carrying out measurements of a number of cell parameters, including open circuit voltage, time and temperature, with accuracies large enough to allow for precise determination of thermodynamic state functions and materials properties relating to the composition, phase, states of charge, health and safety and electrochemical properties of electrodes and electrolytes in an electrochemical cell. Thermodynamic measurement systems of the present invention are highly versatile and provide information for predicting a wide range of performance attributes for virtually any electrochemical system having an electrode pair.
Type:
Grant
Filed:
April 26, 2013
Date of Patent:
March 21, 2017
Assignees:
CALIFORNIA INSTITUTE OF TECHNOLOGY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), NANYANG TECHNOLOGICAL UNIVERSITY
Abstract: The present invention relates to a method for preparing a polymer based on N-vinyl lactam monomer units, which comprises a step (E) for controlled radical polymerization of a composition comprising: monomers containing (and most often consisting of) N-vinyl lactam monomers, either identical or different (and generally identical); an agent for controlling the radical polymerization, for example comprising a thiocarbonylthio group —S(C?S)—; and a radical polymerization initiator which is a redox system comprising a reducing agent (Red) and an oxidizing agent (Ox).
Type:
Grant
Filed:
September 22, 2011
Date of Patent:
February 21, 2017
Assignees:
RHODIA OPERATIONS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
Inventors:
Mathias Destarac, Aymeric Guinaudeau, Stéphane Mazieres, James Wilson
Abstract: A process for preparing a magnetic talcous composition including mineral particles, referred to as magnetic talcous particles, having a non-zero magnetic susceptibility, in which, during an oxidative contacting step, talcous particles chosen from the group formed from 2:1 lamellar silicates having a zero electric charge are brought into contact with particles including at least one magnetic iron oxide chosen from the group formed from magnetite and maghemite, the magnetic particles having a mean equivalent diameter of between 1 nm and 50 nm. A magnetic talcous composition including mineral particles, referred to as magnetic talcous particles, having a non-zero magnetic susceptibility, at least 20% by weight of talcous particles and at least 0.5% by weight of magnetic particles is also described.
Type:
Grant
Filed:
December 21, 2012
Date of Patent:
February 14, 2017
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE PAUL SABATIER TOULOUSE III
Inventors:
Francois Martin, Pierre Micoud, Angela Dumas, Christophe Le Roux, Emmanuel Gardes
Abstract: The present invention relates to the use (i) of a level of expression of a long RBM39 protein isoform, termed RBM39L, and (ii) of a level of expression of a short RBM39 protein isoform, termed RBM39C, as a marker for the efficacy of an active agent capable of preventing and/or treating HIV infection.
Type:
Grant
Filed:
March 4, 2013
Date of Patent:
January 31, 2017
Assignees:
ABIVAX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE DE MONTPELLIER, INSTITUT CURIE
Abstract: The invention relates to a method for simulating the movements of a virtual vehicle, a user being in physical contact with a simulator including a force-feedback haptic interface, wherein said physical contact corresponds to at least one physical point of contact between the haptic interface and the body of the user that is representative of a virtual point of contact between the user and the virtual vehicle. Said method comprises at least two steps. A first step involves determining a linear acceleration vector (formula (I)) and a linear velocity vector (formula (II)) at the virtual point of contact between the user and the virtual vehicle, said vectors being representative of the movement of the vehicle at said point.
Type:
Grant
Filed:
September 14, 2010
Date of Patent:
January 31, 2017
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET EN AUTOMATIQUE
Abstract: A method of controlling a machine with redundant parallel actuation includes a frame and a mobile element driven by a plurality of mechanical transmissions parallel to one another and each being activated by an actuator (2) including a body fixed to the frame, an actuating member and a position sensor, in which an error signal is produced by comparing the position of each actuator with a setpoint signal, characterized in that the error signals are converted into a mobile element position error signal by applying data representative of the kinematics of the mechanical transmissions, the mobile element error signal is processed by a processing module which produces an effort signal to be applied to the mobile element, the effort signal is converted into signals controlling the actuators by applying data representative of the kinematics of the mechanical transmissions.
Type:
Grant
Filed:
August 8, 2012
Date of Patent:
January 17, 2017
Assignees:
TECNALIA FRANCE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
Inventors:
Francois Pierrot, Ahmed Chemori, Micaël Michelin
Abstract: A method for preparing a composition including silicate mineral particles that have coloring properties in which a talcose composition, including phyllosilicate mineral particles chosen from the group formed: from the particles having the chemical formula: ((SixGe1-x)4 M3O10 (OH)2, the particles having at least one interlayer space and having the chemical formula: (SixGe1-x)4 M3-? O10 (OH)2, (M?m+)??.nH2O: -M having the formula Mgy(1)Coy(2)Zny(3)Cuy(4)Mny(5) Fey(6)Niy(7)Cry(8); -M?m+ designating at least one interlayer cation, the silicate mineral particles having a thickness of less than 100 nm and of which the largest dimension is less than 10 ???, is brought into contact with a dye solution, including dye cations, of at least one element chosen from the transition metals, the lanthanides and the actinides. The composition obtained by this method is also described.
Type:
Grant
Filed:
September 20, 2013
Date of Patent:
January 10, 2017
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE PAUL SABATIER TOULOUSE III
Inventors:
Francois Martin, Emmanuel Gardes, Pierre Micoud, Christophe Le Roux
Abstract: A colloidal dispersion of a metal chalcogenide material in divided state in an aqueous liquid phase selected from the group consisting of aqueous solutions and solutions including a mixture of water and at least one solvent that is miscible with water, wherein the carbon element of the material is present in a proportion of less than 2.5 wt. % as determined by elemental analysis, the concentration of the material in the colloidal dispersion is more than 40 g/l, and the colloidal dispersion has a charge potential value which is negative and the absolute value of which is higher than 20 mV.
Type:
Grant
Filed:
March 7, 2012
Date of Patent:
December 20, 2016
Assignees:
UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE, ECOLE SUPERIEURE DES BEAUX-ARTS DE LA REUNION
Inventors:
Jean-Yves Chane-Ching, Oana Zaberca, Azmach Tolesa, Andrea Balocchi
Abstract: The invention relates to a method for generating a focused charged-particle beam, comprising at least the steps of: a) generating a charged-particle beam (10); b) emitting a laser pulse (40); c) generating a focusing magnetic field structure in a target (50) by means of an interaction between the laser pulse and the target; and d) making the charged-particle beam penetrate the focusing magnetic field structure at least partially.
Type:
Grant
Filed:
October 22, 2013
Date of Patent:
December 6, 2016
Assignees:
ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (INRS)
Inventors:
Julien Fuchs, Bruno Albertazzi, Henri Pepin, Emmanuel D'Humieres
Abstract: A method for preparing a composition including synthetic mineral particles, in which: a hydrogel that is a precursor of the synthetic mineral particles is prepared, and the hydrogel is subjected to a hydrothermal treatment, characterized in that at least one step of the hydrothermal treatment is carried out with the addition of at least one carboxylate salt to the treatment medium, the carboxylate salt having the formula R—COOM?, where M? denotes a metal selected from the group consisting of Na and K, and R is selected from H and the alkyl groups that include fewer than 10 carbon atoms.
Type:
Grant
Filed:
December 22, 2011
Date of Patent:
November 29, 2016
Assignees:
UNIVERSITE PAUL SABATIER TOULOUSE III, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
Inventors:
Christophe Le Roux, Francois Martin, Pierre Micoud, Angela Dumas
Abstract: Long-chain alkyl cyclic acetals made from sugars are obtainable by a method that comprises the steps consisting of: dehydrating a hexitol in a monoanhydrohexitol substrate; reacting the monoanhydrohexitol substrate obtained with an alkyl aldehyde reagent containing 5 to 18 carbon atoms, by means of an acetalization reaction with a substrate/reagent ratio of between 5:1 and 1:1, or with a derivative of an alkyl aldehyde reagent containing 5 to 18 carbon atoms, by means of a transacetalization reaction with a substrate/reagent ratio of between 1:1 and 1:3, in the presence of acid catalyst and in an environment that is free of solvent or that consists of non-aqueous polar solvent; collecting the long-chain alkyl acetal of hexitan from the mixture obtained.
Type:
Grant
Filed:
June 13, 2014
Date of Patent:
November 22, 2016
Assignees:
SYRAL BELGIUM NV, UNIVERSITÉ CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
Inventors:
Charlotte Gozlan, Nicolas Duguet, Marc Lemaire, Yves Queneau, Andreas Redl
Abstract: A method for preparing 2,5-furandicarboxylic acid (FDCA) by oxidizing 5-hydroxymethylfurfural (HMF) in water in the presence of a weak base and a supported catalyst comprising platinum and bismuth, in which the Bi/Pt molar ratio in the catalyst is between 0.1 and 0.3, and preferably between 0.15 and 0.3.
Type:
Grant
Filed:
February 11, 2014
Date of Patent:
November 22, 2016
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE CLAUDE BERNARD LYON 1
Inventors:
Michele Besson, Nadine Essayem, Hicham Ait Rass
Abstract: A piezoelectric and ferroelectric bulk wave transducer operating at a predetermined frequency includes a block of substrate, having a first thickness and in a first material, and a piezoelectric and ferroelectric transduction plate, having a length, a width and a second thickness, and in a second piezoelectric material, first and second metal electrodes covering the plate in the direction of the length thereof. The plate has first and second ferroelectric domains with alternating polarizations, distributed along the length of the plate according to a periodic pattern of pitch. The plate is attached perpendicularly to the block so that the width of the plate and the first thickness of the block are the same direction. The first and second material, the first thickness of the block, the length, the width, the second thickness, the pitch of the plate are configured for generating and trapping bulk waves at the operating frequency of the transducer, guided between both electrodes.
Type:
Grant
Filed:
October 5, 2012
Date of Patent:
November 15, 2016
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE DE FRANCHE-COMTE
Abstract: A storage device, comprising at least one spintronic element suitable for representing a state among at least n states associated with the spintronic element, n>1, characterized in that each of the n states is associated with at least one characteristic of a group of magnetic skyrmions in the spintronic element, and in that said characteristic associated with a state n ?i is different from said characteristic associated with a state n ?j when the states n ?i and n ?j are two different states among the n states.
Type:
Application
Filed:
August 1, 2014
Publication date:
October 27, 2016
Applicants:
THALES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)
Inventors:
Vincent Cros, Albert Fert, Joao Sampaio, Pierre Seneor