Patents Assigned to CHA University Industry-Academic Cooperation Foundation
  • Patent number: 10987295
    Abstract: Provided is a novel peptide and a cosmetic composition for inhibiting a skin-aging or a skin-wrinkle formation including the same. The peptide has activities for facilitating the bindings between keratinocytes; and increasing the expressions of junction proteins significantly.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: April 27, 2021
    Assignee: College of Medicine Pochon CHA University Industry-Academic Cooperation Foundation
    Inventors: Ji-Hyung Chung, Da-Yoon Chung
  • Publication number: 20210054335
    Abstract: A method for increasing dendritic cell migration ability, and a use thereof are disclosed. A method according to one aspect can increase the migration ability of mature dendritic cells and increase the induction, by dendritic cells, of inflammatory cytokine production, T lymphocyte proliferation and T lymphocyte polarization, and thus can be used for the prevention or treatment of immune-related diseases.
    Type: Application
    Filed: January 28, 2019
    Publication date: February 25, 2021
    Applicant: CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Dae Seog LIM, Su Yeoun PARK, Jun Ho LEE, So Yeon CHOI, Ji Young YOO, Nam Chul JUNG
  • Publication number: 20210047615
    Abstract: An aspect provides a method of increasing efficiency of somatic cell nuclear transfer using a substance (RS-1) increasing Rad51 activity, and a somatic cell nuclear transfer cell prepared according to the method. Another aspect provides a method of screening for a substance increasing Rad51 activity to increase efficiency of somatic cell nuclear transfer. When the substance increasing Rad51 activity is used, efficiency of somatic cell nuclear transfer may be increased.
    Type: Application
    Filed: January 23, 2019
    Publication date: February 18, 2021
    Applicant: CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Dong Ryul LEE, Kyung Soon PARK, Ah Reum LEE
  • Publication number: 20210032619
    Abstract: The present invention provides a vector library for yeast two-hybrid screening of a deubiquitinating enzyme that binds to a target protein and a method for identifying a deubiquitinating enzyme binding to a target protein using the same. Also, the present invention provides a method for screening an agent having anti-cancer activity targeting the deubiquitinating enzyme USP1, USP7, USP12, or USP49 identified by said identifying method.
    Type: Application
    Filed: August 6, 2018
    Publication date: February 4, 2021
    Applicant: CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Kwang-Hyun BAEK, So-Ra KIM, Seul-Ki KWON, Soo-Yeon KIM, Da-Hye LEE
  • Publication number: 20200315941
    Abstract: Provided is a novel peptide and a cosmetic composition for inhibiting a skin-aging or a skin-wrinkle formation including the same. The peptide has activities for facilitating the bindings between keratinocytes; and increasing the expressions of junction proteins significantly.
    Type: Application
    Filed: June 23, 2020
    Publication date: October 8, 2020
    Applicant: College of Medicine Pochon CHA University Industry-Academic Cooperation Foundation
    Inventors: Ji-Hyung CHUNG, Da-Yoon CHUNG
  • Patent number: 10729635
    Abstract: Provided is a novel peptide and a cosmetic composition for inhibiting a skin-aging or a skin-wrinkle formation including the same. The peptide has activities for facilitating the bindings between keratinocytes; and increasing the expressions of junction proteins significantly.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: August 4, 2020
    Assignee: College of Medicine Pochon CHA University-Industry-Academic Cooperation Foundation
    Inventors: Ji-Hyung Chung, Da-Yoon Chung
  • Publication number: 20200239853
    Abstract: Provided are stem cells-induced Serotoli-like cells, methods of preparing the same, and uses thereof. Sertoli-like cells according to one embodiment can be differentiated from embryonic stem cells with excellent proliferative capacity, and thus, can be obtained in large quantities. Also, since the Sertoli-like cells secrete immunosuppressive substances and form immune privilege and induce anti-inflammatory functions, they can be used for development of the cell therapeutic agent.
    Type: Application
    Filed: March 6, 2020
    Publication date: July 30, 2020
    Applicant: CHA University Industry-Academic Cooperation Foundation
    Inventors: Dong Ryul LEE, Dong Won Seol
  • Publication number: 20200153777
    Abstract: A deep learning-based social mashup logic implementation system, includes a user interface server configured to store data about a user's personal information, login information, activity information, and the like of web- and mobile-based interfaces, an external link server configured to store data about activities, a situation recognition server configured to sense mental and environmental changes of the user and store data related to the mental and environmental changes of the user, an analysis server configured to generate and store a relationship index obtained by numerically calculating a relationship between the user and the other user with an artificial neural network, and a management server configured to adjust a level of the other user's access to the user's posts and a level of exposing content uploaded by the user.
    Type: Application
    Filed: December 12, 2018
    Publication date: May 14, 2020
    Applicant: CHA University Industry-Academic Cooperation Foundation
    Inventor: TaiKyeong Jeong
  • Publication number: 20200129592
    Abstract: Provided are a composition for treating stroke and a method of screening for the same, and a pharmaceutical composition for treating stroke, the pharmaceutical composition including an IL-1 receptor antagonist as an active ingredient, and a method of screening for a therapeutic agent for stroke using the same.
    Type: Application
    Filed: August 16, 2019
    Publication date: April 30, 2020
    Applicants: CHA University Industry-Academic Cooperation Foundation, CHA BIOTECH CO., LTD.
    Inventors: Ji Hwan Song, Seung Hun Oh, Hye Sun Kim, Min Ji Lee, Ji Hye Kim
  • Publication number: 20200103422
    Abstract: Provided are a biomarker for diagnosing of the level of senescence, a composition and kit for diagnosing of the level of senescence to detect the biomarker, and a method of diagnosing the same. According to the composition and kit for the diagnosis of the level of senescence and the method of diagnosing senescence, the level of senescence of a subject is easily diagnosed, the health conditions of the subject are monitored, and a senescence-associated disease is prevented or diagnosed.
    Type: Application
    Filed: November 30, 2018
    Publication date: April 2, 2020
    Applicants: CHA University Industry-Academic Cooperation Foundation, The General Hospital Corporation
    Inventors: Ji Sook MOON, Hak Ho LEE, Ala JO, Jae Hyun PARK, Ji Min PARK, Chul Woo LIM, Yu Ri CHOI
  • Patent number: 10478392
    Abstract: Provided herein is a peptide, a cosmetic composition comprising the same, and a method for inhibiting skin-aging or skin-wrinkle formation using the same, the peptide having activities for facilitating the bindings between keratinocytes; and increasing the expressions of junction proteins.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: November 19, 2019
    Assignee: College of Medicine Pochon CHA University Industry-Academic Cooperation Foundation
    Inventor: Ji-Hyung Chung
  • Publication number: 20190274942
    Abstract: Provided is a novel peptide and a cosmetic composition for inhibiting a skin-aging or a skin-wrinkle formation including the same. The peptide has activities for facilitating the bindings between keratinocytes; and increasing the expressions of junction proteins significantly.
    Type: Application
    Filed: October 30, 2017
    Publication date: September 12, 2019
    Applicant: College of Medicine Pochon CHA University Industry-Academic Cooperation Foundation
    Inventors: Ji-Hyung CHUNG, Da-Yoon CHUNG
  • Publication number: 20190194591
    Abstract: Provided are a support for culturing cells, a method of preparing the support, and a method of culturing cells using the support. When the support and the methods are used, an adherence rate, a surface area, and a proliferation rate of cells may improve, and detachment of the cells may be facilitated, thereby increasing a cell recovery rate. In addition, a physiologically active substance may be slowly released, thereby reducing the cost for a cell culture process.
    Type: Application
    Filed: October 23, 2018
    Publication date: June 27, 2019
    Applicant: CHA University Industry-Academic Cooperation Foundation
    Inventors: Surin HONG, Yong Soo CHOI
  • Patent number: 10280402
    Abstract: The present invention relates to a method for producing immune-compatible cells or a cell population which comprises a step of editing one or two alleles of one or more immune-compatible antigen genes by gene deletion or modification in an isolated cell comprising at least one of the immune-compatible antigen genes selected from HLA (human leukocyte antigen)-A, HLA-B and HLA-DR, to immune-compatible cells produced by the method, and to a cell population comprising the immune-compatible cells produced by the method.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: May 7, 2019
    Assignees: COLLEGE OF MEDICINE POCHON CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, INSTITUTE FOR BASIC SCIENCE
    Inventors: Jin Soo Kim, Dong Youn Hwang
  • Publication number: 20180325794
    Abstract: Provided herein is a peptide, a cosmetic composition comprising the same, and a method for inhibiting skin-aging or skin-wrinkle formation using the same, the peptide having activities for facilitating the bindings between keratinocytes; and increasing the expressions of junction proteins.
    Type: Application
    Filed: October 27, 2016
    Publication date: November 15, 2018
    Applicant: College of Medicine Pochon CHA University Industry -Academic Cooperation Foundation
    Inventor: Ji-Hyung CHUNG
  • Publication number: 20170306283
    Abstract: The present invention relates to a trypsin-free cell stamp system and a use thereof. According to the present invention, an increase in the passage number of stem cells can be prevented compared with conventional methods of isolating cells from a cell culture dish, while providing a support, which is an essential condition of cell growth, by introducing the trypsin-free cell stamp system, and cells can be continuously supplied for a polymer-based fiber support without an additional subculture process since the empty space of a cell culture dish is filled as times passes. In addition, the artificial effects on cells can be minimized since the cells migrate to a polymer-based nano/micro-fiber support without other external stimulation, and thus the potency of stem cells is increased, thereby inducing more effective differentiation, such that the present invention, as a cell therapeutic agent, can be utilized in general fields of regenerative medicine and tissue engineering.
    Type: Application
    Filed: October 20, 2015
    Publication date: October 26, 2017
    Applicant: COLLEGE OF MEDICINE POCHON CHA UNIVERSITY INDUSTRY -ACADEMIC COOPERATION FOUNDATION
    Inventors: Han Soo PARK, Ah Yeon RYANG, Ha Ram LEE, Soo Hong LEE, In Bo HAN, Byoung Ju KIM
  • Publication number: 20170296582
    Abstract: The present invention provides a method for proliferating neural progenitor cells and a composition for treating neurological diseases, the composition including a proliferated neural progenitor cell. When a fetal neural progenitor cell is cultured under a hypoxia condition and/or in a medium containing tocoperol, tocoperol acetate, or a mixture thereof, the improved cell proliferation rates of the fetal neural progenitor cell are confirmed. In addition, considering an effect of the neural progenitor cell on preventing differentiation thereof into neurons at the time of proliferation, the present disclosure may contribute to mass production of neural stem cells, and accordingly, the proliferated neural progenitor cell is expected to be utilized in the treatment of a neurological disease.
    Type: Application
    Filed: October 10, 2014
    Publication date: October 19, 2017
    Applicant: COLLEGE OF MEDICINE POCHON CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Ji-Sook MOON, Hyun-Seob LEE, Yeon-Ho SHIN
  • Publication number: 20130089926
    Abstract: The present invention provides a method for differentiating human neural progenitor cells into dopaminergic neurons, comprising the step of culturing human neural progenitor cells in a medium containing fusaric acid. In addition, the present invention provides a medium for differentiation of human neural progenitor cells into dopaminergic neurons.
    Type: Application
    Filed: June 7, 2011
    Publication date: April 11, 2013
    Applicant: College of Medicine Pochon Cha University Industry - Academic Cooperation Foundation
    Inventor: Ji-Sook Moon
  • Publication number: 20120238019
    Abstract: The present invention provides a medium for maintaining stemness of stem cells comprising a protein kinase C inhibitor in a basal medium; and a method for culturing stem cells while maintaining stemness thereof, using the same. And also, the present invention provides a medium for inducing differentiation of stem cells comprising a protein kinase C activator in a basal medium; and a method for inducing differentiation of stem cells, using the same.
    Type: Application
    Filed: March 18, 2011
    Publication date: September 20, 2012
    Applicant: COLLEGE OF MEDICINE POCHON CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Dong-Youn HWANG, Tae-Min YOON
  • Patent number: 7947497
    Abstract: Provided are methods for the vitrification of human oocytes, which comprises: (a) placing human oocytes on a transfer instrument; and (b) placing the transfer instrument and the human oocytes directly into a slushed nitrogen (N2 slush), wherein the human oocytes are directly exposed to the N2 slush thereby undergoing vitrification, and wherein the human oocytes are able to live for a period of time after the human oocytes are devitrified.
    Type: Grant
    Filed: April 17, 2006
    Date of Patent: May 24, 2011
    Assignees: Chabio&Diostech Co. Ltd., College of Medicine Pochon Cha University Industry-Academic Cooperation Foundation
    Inventors: Tae Ki Yoon, Dong Ryul Lee, Hyung Min Chung, Kwang Yul Cha