Patents Assigned to Cheng Kung University
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Publication number: 20250142917Abstract: A composite structure includes a dielectric layer, a two-dimensional graphene layer and a carbon quantum dot film. The dielectric layer is disposed on a first surface of a silicon substrate. The two-dimensional graphene layer is disposed on the dielectric layer. The carbon quantum dot film is disposed on the two-dimensional graphene layer.Type: ApplicationFiled: December 14, 2023Publication date: May 1, 2025Applicant: National Cheng Kung UniversityInventors: Chia-Yun CHEN, Zhe-Hao LIU, Kuan-Han LIN, Jheng-Yi LI
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Patent number: 12287292Abstract: A method for detecting an analyte comprises the following steps: providing a SERS-active substrate and a Raman spectra database; applying a sample onto the SERS-active substrate; applying an incident light by a Raman spectrometer onto the SERS-active substrate to generate a Raman spectrum of the sample; and comparing the Raman spectrum of the sample with a Raman spectra database to identify an analyte in the sample. The SERS-active substrate comprises: a support; a first dielectric layer disposed on the support, wherein the first dielectric layer is formed by a plurality of first nanofibers; and a plurality of noble metal particles formed on the plurality of first nanofibers.Type: GrantFiled: June 8, 2023Date of Patent: April 29, 2025Assignee: National Cheng Kung UniversityInventors: Jiunn-Der Liao, Han Lee, Kuan-Hung Liu
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Publication number: 20250101965Abstract: A pulsed-plasma thruster using an unbalanced theta-pinch includes a gas-puff generator, an ionization convergent-divergent nozzle, and an accelerating coil set. The gas-puff generator supplies a gas puff in a pulsed manner; and the accelerating coil set is arranged on a side of a throat of the ionization convergent-divergent nozzle. After the gas puff enters the ionization convergent-divergent nozzle, an electric arc is generated between the pair of electrodes of the ionization convergent-divergent nozzle so that the gas puff is ionized and forms a plasma plume, and the electrodes are utilized to drive the accelerating coil set to generate axially non-uniform magnetic fields, to accelerate the plasma plume. Based on this, the control of thrust force generation is simple and reliable, with high energy utilization efficiency.Type: ApplicationFiled: January 4, 2024Publication date: March 27, 2025Applicant: National Cheng Kung UniversityInventors: Po-Yu CHANG, Te-Yueh CHEN
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Publication number: 20250062757Abstract: A multiple-reference-embedded comparator (MREC) circuit includes a tail current source circuit; an input transistor pair, coupled to the tail current source circuit, configured to receive differential input voltages and perform a first pre-amplification to generate first differential amplified voltages according to the differential input voltages; and a plurality of embedded reference (ER) branches, each coupled to the input transistor pair, each configured to perform a second pre-amplification to generate second differential amplified voltages according to the first differential amplified voltages, and to perform a discrete-time comparison to generate differential output voltages according to the second differential amplified voltages.Type: ApplicationFiled: August 16, 2023Publication date: February 20, 2025Applicant: National Cheng Kung UniversityInventors: Jia-Ching Wang, Tai-Haur Kuo
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Publication number: 20250061069Abstract: An accelerator system includes an off-chip memory, a bus, and an accelerator. The off-chip memory includes a first buffer. The accelerator includes a second buffer, a third buffer, a fourth buffer, an instruction fetching module, a load module, a storage module, a convolution control module, and a computation module. The instruction fetching module fetches instructions from the off-chip memory via the bus. The load module loads input data from the off-chip memory via the bus. The storage module stores the output data to the off-chip memory via the bus. The computation module performs convolution computations based on the input map and multiple kernels allocated by the convolution module. In response to loading the input data or instruction from the off-chip memory, the requested input data or instruction is transferred from the off-chip memory and temporarily stored in the first buffer.Type: ApplicationFiled: November 15, 2023Publication date: February 20, 2025Applicant: National Cheng Kung UniversityInventors: Chung-ho CHEN, Cheng-you XIE
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Publication number: 20250035666Abstract: A shear mode piezoelectric accelerometer includes a ring-shaped piezoelectric element, a central shaft, a mass block, a first electrode, and a second electrode. The ring-shaped piezoelectric element includes an outer ring wall and an inner ring wall. The central shaft is made of conductive material and is fixed through the inner ring wall of the ring-shaped piezoelectric element. The mass block is made of conductive material and includes a fixed element and a weight element. The fixed element has a fixed hole and is fixed to the outer ring wall of the ring-shaped piezoelectric element by fitting the fixed hole. The weight element is located on the fixed element on the opposite side away from the fixed hole. The first electrode is electrically connected to the central shaft. The second electrode is electrically connected to the mass block.Type: ApplicationFiled: August 29, 2023Publication date: January 30, 2025Applicant: National Cheng Kung UniversityInventors: Cheng-Ying LI, Sheng-Yuan CHU
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Patent number: 12207962Abstract: The present invention relates to a method for measuring muscle mass, including: a first selection step, wherein a frame selection information is obtained by using a frame to select a fascia region from a provided computed tomography image under the condition that the window width ranges from 300 HU to 500 HU and the window level ranges from 40 HU to 50 HU, wherein the selected range of the fascia region includes a muscle; and a second selection step, wherein a muscle information of the muscle is obtained by calculating a pixel value in the frame-selected fascia region under the condition that the HU value of the CT image ranges from ?29 HU to 150 HU.Type: GrantFiled: April 20, 2022Date of Patent: January 28, 2025Assignee: National Cheng Kung UniversityInventors: Yi-Shan Tsai, Yu-Hsuan Lai, Bow Wang, Cheng-Shih Lai, Chao-Yun Chen, Meng-Jhen Wu, Po-Tsun Kuo, Tsung-Han Lee
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Patent number: 12202825Abstract: Pyrimidine compounds of formula (I) shown herein. Also disclosed are pharmaceutical compositions containing one of the pyrimidine compounds and methods of using the pyrimidine compounds to treat or prevent chemotherapy-induced peripheral neuropathy.Type: GrantFiled: July 29, 2022Date of Patent: January 21, 2025Assignees: National Health Research Institutes, National Cheng Kung UniversityInventors: Jang-Yang Chang, Meng-Ru Shen, Kak-Shan Shia, Chien-Huang Wu
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Publication number: 20250023439Abstract: An offset overlap type of a modulated ferromagnetic pole piece ring and a manufacturing method thereof are provided. The modulated ferromagnetic pole piece ring comprises a plurality of ring pieces overlapped with each other. At least one ring piece comprises a plurality of main ribs, a plurality of inner ribs, and a plurality of outer ribs. The main ribs are arranged in a circular manner with intervals in between, and a plurality of first gaps and a plurality of second gaps are formed alternately between the main ribs, wherein the inner ribs are respectively located in the first gaps, and the outer ribs are respectively located in the second gaps.Type: ApplicationFiled: April 10, 2024Publication date: January 16, 2025Applicant: National Cheng Kung UniversityInventors: Mi-ching TSAI, Po-wei HUANG, Wen-hao YANG, Tsung-wei CHANG
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Patent number: 12196550Abstract: An optical measurement system measuring optical parameters of an object is provided. The object includes at least two light-transmitting layers. The optical measurement system includes a light source module, an image capture module, and a controller. The light source module emits at least two measurement light beams toward the object. The measurement light beams are respectively incident on the object at different angles. The image capture module receives light spots formed on a sensing surface of the image capture module by at least two first light beams after the measurement light beams are reflected by the object and at least two second light beams after the measurement light beams are refracted and reflected between the object. The controller is electrically connected to the image capture module to obtain positions of the light spots. The controller calculates the optical parameters of the object according to the positions of the light spots.Type: GrantFiled: August 24, 2022Date of Patent: January 14, 2025Assignee: National Cheng-Kung UniversityInventors: Chien-Sheng Liu, Wen-Yu Shih
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Patent number: 12186397Abstract: A cell tissue gel, comprising one or more matrix molecules cross-linked with a cross-linking agent, and a quenching agent bound to a reactive group of the cross-linking agent, wherein the quenching agent contains a moiety that is capable of reacting with the reactive group of the cross-linking agent and the one or more matrix molecules contain one or more functional groups that are capable of cross-linking with the reactive group, the amount of the reactive group of the cross-linking agent being equal to or less than a total amount including the amount of the one or more functional groups and the amount of the moiety.Type: GrantFiled: October 29, 2018Date of Patent: January 7, 2025Assignee: National Cheng Kung UniversityInventor: Lynn L. H. Huang
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Publication number: 20240414931Abstract: An organic/inorganic composite structure includes a silicon substrate and a conductive polymer layer. The silicon substrate includes a plurality of microstructures disposed on a surface of the silicon substrate. The conductive polymer layer is disposed on the plurality of microstructures. A spaced distance is between the conductive polymer layer and the surface of the silicon substrate.Type: ApplicationFiled: July 28, 2023Publication date: December 12, 2024Applicant: National Cheng Kung UniversityInventors: Chia-Yun Chen, Jheng-Yi Li, Tsung-Yen Wu
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Patent number: 12163242Abstract: A method of manufacturing colorful thermal insulation films is provided. A substrate is connected with a metal adhesion layer and then the metal adhesion layer is connected with a porous anodic aluminum oxide (AAO) layer. A porosity of the AAO layer is changed by pore-widening. Thereby the thermal insulation film produced shows the color by the structure color of the AAO layer. Thus no dyes and organic compounds are required to be added during manufacturing process and environmental pollution caused by these substances can be avoided. The pore-widening changes the porosity of the AAO layer and further provides convenient color adjustment so that the colorful thermal insulation film with different colors can be produced easily. Besides providing attractive appearance, the colorful thermal insulation film filters out light with specific wavelengths.Type: GrantFiled: March 6, 2023Date of Patent: December 10, 2024Assignee: National Cheng Kung UniversityInventors: Chen-Kuei Chung, Chung-Yu Yu, Tsung-Han Chen
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Patent number: 12114573Abstract: A method for manufacturing a thermoelectric polymer film includes steps as follows. A conductive polymer liquid and a plurality of carbon nanotubes are mixed to form a mixture. The mixture is coated on a substrate to form a film precursor. Two electrode parts are arranged on the film precursor. An electric field is applied to the film precursor through the two electrode parts at a room temperature, so as to change an arrangement of the plurality of carbon nanotubes, such that the thermoelectric polymer film is formed.Type: GrantFiled: March 3, 2022Date of Patent: October 8, 2024Assignee: National Cheng Kung UniversityInventors: Chia-Yun Chen, Kuan-Yi Kuo, Po-Hsuan Hsiao, Yi-Yin Lin
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Patent number: 12091677Abstract: The present invention provides a carboxylated nanodiamond-mediated CRISPR-Cas9 delivery system for gene editing comprising nanodiamond (ND) particles as the carriers of CRISPR-Cas9 components designed to introduce the mutation in a given gene for repairing a tissue damage.Type: GrantFiled: October 15, 2020Date of Patent: September 17, 2024Assignees: Taipei Veterans General Hospital, National Chiao Tung University, National Cheng Kung UniversityInventors: Shih-Hwa Chiou, Tien-Chun Yang, Chia-Ching Chang, Yon-Hua Tzeng
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Patent number: 12078542Abstract: An optical sensor circuit is provided. In the optical sensor circuit, an output stage circuit transmits a voltage of first and second node to the output line according to a first driving signal. A first sensor is configured to generate a first photocurrent according to a first color light that senses an ambient light, and generate a second photocurrent according to a second color light. A second sensor is configured to generate a third photocurrent according to a third color light, and generate a fourth photocurrent according to the second color light. In a sensing phase, when the first sensor senses the first color light, and the second sensor senses the third color light, the first sensor adjusts a voltage level of the voltage according to the first photocurrent, and the second sensor adjusts the voltage level of the voltage according to the third photocurrent.Type: GrantFiled: May 11, 2022Date of Patent: September 3, 2024Assignees: Au Optronics Corporation, National Cheng-Kung UniversityInventors: Chih-Lung Lin, Chia-En Wu, Chia-Lun Lee, Jui-Hung Chang, Jian-Shen Yu
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Publication number: 20240220573Abstract: A computing in memory accelerator for applying to a neural network includes a memory, a data buffer unit, a pooling unit, a loss computing unit, a first macro circuit, a second macro unit, a third macro unit, and a multiplexer. The memory is used for saving data. The data buffer unit is coupled to the memory and used to buffer data outputted from the memory. The pooling unit is coupled to the memory and used to pool data for acquiring a maximum pooling value. The loss computing unit is coupled to the memory and used to compute output loss. The first macro circuit, the second macro unit, and the third macro unit are coupled to the data buffer unit. The multiplexer is coupled to the pooling unit, the first macro circuit, the second macro unit, and the third macro unit and used to generate output data.Type: ApplicationFiled: March 7, 2023Publication date: July 4, 2024Applicant: National Cheng Kung UniversityInventors: Lih-Yih Chiou, Yun-Ru Chen, Tsung-Chi Chen
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Publication number: 20240201541Abstract: The present invention provides a liquid crystal display device, which comprises: cholesteric liquid crystals and polymer fragments. By adding polymer fragments, the upper and lower substrates of the liquid crystal display device of the present invention may control the alignment of the liquid crystals and have excellent electro-optical characteristics without the use of an alignment film; furthermore, the polymer fragments are modified with a vertical alignment agent, DMOAP to form a radial structure so as to improve the contrast. The present invention also provides a method for preparing a liquid crystal display device in a simple way, so that the liquid crystal display device has the electro-optical characteristics of high contrast, low threshold voltage, and fast response time.Type: ApplicationFiled: February 22, 2023Publication date: June 20, 2024Applicant: National Cheng Kung UniversityInventors: Chun-Yen Liu, Jui-Hsiang Liu
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Publication number: 20240191135Abstract: A method for reactive ion etching includes multiple steps of: (a) placing a film to be etched in a vacuum chamber; (b) introducing an etching gas into the vacuum chamber; (c) starting a reactive ion etching to etch the film via the etching gas in a first duration; (d) in a second duration, stopping reactive ion etching and extracting the remaining gas in the vacuum chamber to make the vacuum chamber be in a high-clean state; and (e) repeating step (b) to (d) until an etching depth of the film is reached to a predetermined value.Type: ApplicationFiled: December 7, 2022Publication date: June 13, 2024Applicant: National Cheng Kung UniversityInventors: Tse-Ming Chen, Chiu-Hua Huang, Ching-Hua Kao, Yu-Chiang Hsieh
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Publication number: 20240171131Abstract: An amplifier circuit includes an input terminal, configured to receive an input voltage; an output terminal, configured to output an output voltage; a multi-stage operational amplifier, coupled to the input terminal and the output terminal, and configured to amplify the input voltage to the output voltage, comprising a plurality of amplifiers; and a plurality of level-shifting networks, each coupled between two of the plurality of amplifiers, configured to reduce a gain error of each output of the plurality of amplifiers; and a feedback capacitor, coupled between the input terminal and the output terminal.Type: ApplicationFiled: November 21, 2022Publication date: May 23, 2024Applicant: National Cheng Kung UniversityInventors: Jia-Ching Wang, Tai-Haur Kuo