Patents Assigned to Cheng
  • Patent number: 8679760
    Abstract: The present invention relates to a biomarker associated with a cancer and a method using the biomarker to evaluate a risk of proliferation, invasion, or metastasis of a cancer. The method of the present invention comprises the following steps: (A) providing a tissue sample to evaluate for risk of proliferation, invasion, or metastasis of a cancer, wherein the tissue sample comprises a non-cancer region, and a suspected cancer region; (B) detecting expression levels of a biomarker and a predetermined standard in the non-cancer region and the suspected cancer region respectively, wherein the biomarker is T-cell lymphoma invasion and metastasis 2 (TIAM2); (C) comparing the expression levels of the biomarker and the predetermined standard in the non-cancer region to the expression levels of the biomarker and the predetermined standard in the suspected cancer region.
    Type: Grant
    Filed: May 3, 2011
    Date of Patent: March 25, 2014
    Assignee: National Cheng Kung University
    Inventors: H. Sunny Sun, Jia-Shing Chen
  • Publication number: 20140081069
    Abstract: A deep magnetic field generating apparatus includes a first coil unit and a second coil unit. The second coil unit is connected with the first coil unit, and disposed around the first coil unit horizontally. Accordingly, the deep magnetic field generating apparatus can generate a desired deep magnetic field.
    Type: Application
    Filed: February 12, 2013
    Publication date: March 20, 2014
    Applicants: METAL INDUSTRIES RESEARCH & DEVELOPMENT CENTRE, NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Cheng-Chi TAI, Shyh-Jier HUANG, Xi-Zhang LIN, Chien-Chang CHEN, Tsung-Chih YU
  • Publication number: 20140080739
    Abstract: Provided is a capture nanobead with multiple oriented adapting peptides, comprising: a nanobead; and multiple adapting peptides, each adapting peptide specifically recognizing an IgG constant region or fragment thereof and being chemically conjugated with the nanobead, whereby the adapting peptides are orientedly arranged on the nanobead. The capture nanobeads is capable of binding or conjugating with capture molecules such capture antibodies, which is useful as the basis to bind to alternative antibodies or Fab fragments in sandwich immunoassays.
    Type: Application
    Filed: September 19, 2012
    Publication date: March 20, 2014
    Applicant: National Cheng Kung University
    Inventor: Lynn Ling-Huei Huang
  • Publication number: 20140077870
    Abstract: A digitally controlled non-inverting buck-boost DC-DC converter system including a non-inverting buck-boost DC-to-DC converter control module and a negative feedback module and applicable for a radio frequency circuit module is revealed. By locking a duty cycle to two specific levels, the non-inverting buck-boost DC-to-DC converter control module only needs a single operation mode to achieve the required effects. Simultaneously, pulse-skipping phenomenon is also avoided. Furthermore, a reference voltage is modified through a reference voltage correction circuit of the negative feedback module to eliminate errors between previous DC output voltage and the reference voltage. Thereby the DC output voltage can remain in a stable state so as to reduce operational defects during the mode transition.
    Type: Application
    Filed: January 9, 2013
    Publication date: March 20, 2014
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: HAN-CHIEN LIU, CHIEN-HUNG TSAI, YU-SHIN TSAI
  • Patent number: 8673358
    Abstract: The present invention relates to a nano-carrier for an anticancer drug, which comprises: a metal nanoparticle; and a polynucleotide for connecting with an anticancer drug having a pyrimidine group or a purine group, wherein the polynucleotide connects to a surface of the metal nanoparticle, and the anticancer drug binds to the polynucleotide through the pyrimidine group or the purine group. In addition, the present invention also provides a complex of an anticancer drug and a nano-carrier, a pharmaceutical composition thereof, a method for manufacturing the complex, and a method for treating a cancer by using the pharmaceutical composition.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: March 18, 2014
    Assignee: National Cheng Kung University
    Inventors: Dar-Bin Shieh, Chen-Sheng Yeh, Dong-Hwang Chen, Ya-Na Wu, Ping-Ching Wu
  • Patent number: 8673672
    Abstract: In the present invention, copper(I) selenide (Cu2-xSe) nanoparticles are fabricated by pyrolysis in an inert atmosphere. Uniformly dispersed Cu2-xSe particles are synthesized by altering Cu/Se ratio, the concentration of Se Precursors (TOP Se), reaction time and temperature. Analysis by inductively coupled plasma atomic emission spectroscopy (ICP-AES) of said Cu2-xSe nanoparticles reveals that the composition of the nanoparticles is Cu 1.95Se, wherein x=0.05. In addition, Cu2-xSe is dissolved in ethanol to deposit thin films by electrophoretical deposition (EPD) in an inert atmosphere, wherein a positive electrode and a negative electrode are employed. The positive electrode is made of stainless steel plate and the negative electrode is made of indium tin oxide on a glass substrate. Investigations on properties and surface morphology thereof in different electrophoretical conditions are carried out. The rate of EPD is found to significantly influence the quality of thin films.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: March 18, 2014
    Assignee: National Chung Cheng University
    Inventors: Chu-Chi Ting, Wen-Yuan Lee
  • Patent number: 8671881
    Abstract: A thickness adjustment device for thin-film coating is revealed. The thickness adjustment device for thin-film coating includes a coating device, a support set, and a thickness adjustment unit. The coating device consists of a work piece conveyor that delivers a work piece, and a material supply unit that carries a coating material onto a surface of the work piece to form a film. The support set is connected to the coating device while the thickness adjustment unit is inserted through and mounted on the support set. The thickness adjustment unit includes a scrape part disposed correspondingly to the work piece and used for applying coating material to form the film. The thickness of the film is adjusted according to a controlling force or torque of the thickness adjustment unit that presses downward. Thus the film is coated on the work piece evenly and the film coating quality is increased.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: March 18, 2014
    Assignees: Metal Industries Research & Development Centre, National Chung Cheng University
    Inventors: Jung-Wei Cheng, Chang-Pen Chen, Jeng-Rong Ho, Bo-Ying Li, Yeh-Min Lin
  • Publication number: 20140075026
    Abstract: A cloud database management method is applied in a cloud server system, and the cloud server system has a plurality of databases, and the method includes the following steps. A user end logs on the cloud server system via a network; the user end saves and hacks up a form file having a plurality of field information into the cloud server system; and each database in the cloud server system points to one of the field information in the firm to save the field information of the form file into a corresponding database one by one.
    Type: Application
    Filed: September 13, 2012
    Publication date: March 13, 2014
    Applicant: LUNG CHENG TECHNOLOGY LTD.
    Inventor: JEN CHANG KAO
  • Publication number: 20140074890
    Abstract: A method of synchronously providing data from software and a website is applied in the software installed to the website, and the software creates a database, and the method includes the following steps: a user end enters into the website via a network to login the software; the user end applies for an access of the software; the software sets an authorization level of the user end; the user end obtains the access of the software; the user end creates one or more records of data in the database by the software; the user end sets an authorization level for retrieving and storing the data by the software; and the software retrieves the retrievable data from the database according to the authorization level of each user end and produces a webpage to output the retrieved data.
    Type: Application
    Filed: September 13, 2012
    Publication date: March 13, 2014
    Applicant: LUNG CHENG TECHNOLOGY LTD.
    Inventor: PEI SHIN CHANG
  • Publication number: 20140074496
    Abstract: An assistance system for taking medicine includes at least a pill container, a processing module and an image capturing module. The pill container is for containing a first medicine and has a first barcode corresponding to the first medicine. The image capturing module is coupled to the processing module and for capturing an image having the first barcode. The processing module assists a person (patient) to take medicine according to information of the first barcode.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 13, 2014
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventor: Pei-Hsuan TSAI
  • Publication number: 20140075255
    Abstract: A debugging control system using inside-core events as trigger conditions and a method of the same are revealed. The method includes following steps. First set up at least one trigger condition and a search range of the clock cycle according to internal states of a core under debug. Pause clock and recover clock of each clock cycle within the search range. Retrieve data of scan chains of the core under debug by a shift buffer during the clock pausing. Next combine data of the scan chains by a trigger comparator circuit to form trigger signals and check whether the trigger signals satisfy the trigger condition. If the trigger condition is satisfied or the trigger signal is over the search range, the clock is paused continuingly and internal states of the scan chains of the core under debug are output otherwise the core under debug is recovered.
    Type: Application
    Filed: January 7, 2013
    Publication date: March 13, 2014
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: KUEN-JONG LEE, JIA-WEI JHOU
  • Publication number: 20140073054
    Abstract: The invention provides a yeast strain and a method for making the same. The method has the step of replacing the regulation region upstream of the hsp104 gene in the genome of the yeast, so as to accelerate and prolong the expression span of hsp104 gene and enhance the capability of the yeast to ferment and produce ethanol in a high-temperature environment. The yeast is capable of fermenting glucose at a temperature higher than 42° C. to produce ethanol, or biomass ethanol, wherein the ethanol production ratio based on fermentation of glucose is higher than 97%. Being able to synchronize the degradation/hydrolysis stage and fermentation stage of biomass ethanol producing process, the yeast in accordance with the present invention is able to lower the production cost of biomass ethanol and further raise the productivity with its high ethanol production ratio.
    Type: Application
    Filed: September 11, 2012
    Publication date: March 13, 2014
    Applicant: NATIONAL CHUNG CHENG UNIVERSITY
    Inventors: KUANG-TSE HUANG, Hau-Ren Chen, Wen-Chien Lee, Chang-Yu Wu, Hsin-Cheng Chen, Yu-Long Wu, Meng-Tsu Tsai, Ju-Ping Yeh, Yu-Wei Liang, Yu-Shiuan Lai
  • Patent number: 8668524
    Abstract: An electrical connector includes a first insulating housing having an erect base board and an erect tongue board extending forwards from a front of the base board, flat terminals molded in the first insulating housing and having a contact portion and a first soldering tail which vertically projects under the base board, a second insulating housing assembled to a right side of the base board, and spring terminals molded in the second insulating housing and having a contact arm and a second soldering tail which vertically projects under the second insulating housing. The contact portions are exposed in a front of a right side of the tongue board and arranged at regular intervals along a vertical direction. The contact arms elastically project sideward out of the right side of the tongue board and are arranged at regular intervals along the vertical direction behind the contact portions.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: March 11, 2014
    Assignee: Cheng Uei Precision Industry Co., Ltd.
    Inventors: Rong-Qin Lan, Li-Jun Xu, Ming-Han Lin
  • Patent number: 8669316
    Abstract: Magnetic ion-exchange polymer microspheres and a method for preparing the same are provided. The method for preparing the magnetic ion-exchange polymer microspheres includes swelling the ion-exchange resins and allowing the magnetic nano-particles to enter the interior of the ion-exchange resins. The magnetic ion-exchange resins of the present invention have various functional groups can be introduced onto the surfaces thereof. Therefore, the magnetic ion-exchange resins of the present invention can be applied in many areas, and thereby they have high economic value.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: March 11, 2014
    Assignee: National Chung Cheng University
    Inventors: Wen-Chien Lee, Yu-Zong Lin, Yu-Sheng Lin, Tzu-Hsien Wang
  • Patent number: 8669464
    Abstract: A thermophotovoltaic system is described. The thermophotovoltaic system includes a chamber body, an emitter, a filter and a photovoltaic cell. The chamber body has an ellipsoid chamber including a first focus and a second focus. The emitter is disposed on the first focus, and the emitter is suitable for emitting a plurality of electromagnetic waves. The filter is surrounding the emitter to filter the electromagnetic waves and to pass the electromagnetic waves with a predetermined wavelength band. The photovoltaic cell is disposed on the second focus and is suitable for receiving the electromagnetic waves with the predetermined wavelength band.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: March 11, 2014
    Assignee: National Cheng Kung University
    Inventors: Wen-Chi Hou, Tung-Hsien Wu, Chih-Jui Ni, Chih-Lien Chiang, Chau-Nan Hong
  • Publication number: 20140066940
    Abstract: An assistant device for percutaneous puncture is disclosed. The assistance device includes a fixing element, a first rotatable element, a supporting element and a second rotatable element. The fixing element has a first rail, and the first rotatable element is slidably disposed on the first rail. The supporting element is connected to the first rotatable element. The second rotatable element is slidably disposed on the supporting element and has a puncture restraint pore.
    Type: Application
    Filed: August 20, 2013
    Publication date: March 6, 2014
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Jing-Jing FANG, Ruey-Mo LIN, Hao-Chuan SO, Sheng-Min LAN, Tzu-Chieh WU
  • Publication number: 20140065144
    Abstract: Promoting bone fracture healing in a subject having a bone fracture using an IL-20 antagonist, which can be an antibody that blocks an IL-20-mediated signaling pathway. Such antibodies include anti-IL-20 antibodies and anti-IL-20R1 antibodies capable of blocking the IL-20-mediated signaling pathway.
    Type: Application
    Filed: August 30, 2012
    Publication date: March 6, 2014
    Applicant: National Cheng Kung University
    Inventor: Ming-Shi Chang
  • Publication number: 20140065866
    Abstract: A receptacle connector adapted for engaging with a plug connector includes an inner insulating housing, a plurality of terminals integrally molded to the inner insulating housing, a shielding shell, a waterproof plate and an outer insulating housing. The shielding shell is looped from a first metal plate with an inserting space being formed therein. The inner insulating housing together with the terminals is inserted into the inserting space. The shielding shell defines two buckling holes. The waterproof plate is made of a second metal plate thinner than the first metal plate in thickness, and is fastened on the shielding shell. Two opposite sides of the waterproof plate are punched upward to form two receiving hats corresponding to the two buckling holes. The outer insulating housing is integrally molded around the shielding shell, the waterproof plate and the inner insulating housing with soldering portions of the terminals projected outside.
    Type: Application
    Filed: September 6, 2012
    Publication date: March 6, 2014
    Applicant: Cheng Uei Precision Industry Co., LTD.
    Inventors: Bao-Geng Xie, Wei-Hong Liao, Yin-Lung Wu
  • Publication number: 20140066498
    Abstract: The present invention relates to triterpenoid derivatives, benzenoid derivatives, and pharmaceutical compositions containing the same for treating cancers or inflammatory symptoms. According to the present invention, the triterpenoid derivatives and the benzenoid derivatives are respectively represented by the following formulas (I) and (II): wherein, R1, R2, R3, R4, R5, R6, R7, R8, , , , R1?, R2?, R3?, and R4? are defined the same as the specification.
    Type: Application
    Filed: November 8, 2013
    Publication date: March 6, 2014
    Applicant: National Cheng Kung University
    Inventor: TIAN-SHUNG WU
  • Patent number: 8661636
    Abstract: Provided is a metal shell cutting and assembling machine for cutting a material tape with metal shells and assembling the metal shell with a plastic body of a connector. The metal shell cutting and assembling machine includes a frame, a material-feeding mechanism, a pre-press mechanism, a metal shell-cutting mechanism, a plastic body-inserting mechanism, a metal shell-inserting mechanism and a controller. The material-feeding mechanism is used for transferring the material tape. The pre-press mechanism can pre-press the metal shell of the material tape for being cut by the metal shell-cutting mechanism. The metal shell-inserting mechanism can push the metal shell held between the pre-press mechanism and the metal shell-cutting mechanism onto the plastic body-inserting mechanism, and the plastic body-inserting mechanism pushes the plastic body for assembling with the metal shell. Whereby the metal shell cutting and assembling machine can enhance the manufacture efficiency and reduce the labor cost.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: March 4, 2014
    Assignee: Cheng Uei Precision Industry Co., Ltd.
    Inventors: Yu-feng Lin, Kuo-chuan Chiu, Feng-chi Lee