Abstract: An integral chip is disclosed by embodiments of the present disclosure, including: two mono-mode vertical coupling gratings, two modulation modules, one 2×1 multi-mode interference coupler, and one dual-mode vertical coupling grating. The integral chip is capable of operating in dual wavelengths and dual polarization states by combination of polarization multiplexing and wavelength division multiplexing so as to realize modulation of complex formats and to enhance data modulation rate.

Abstract: The present invention provides a method of aligning a quadrate wafer in a first photolithography process. The method includes: step A: fabricating mask aligning markers in a periphery region of a mask, which is used for a first exposure process of the quadrate wafer, around a mask pattern of the mask; step B: during the first exposure process, positioning the quadrate wafer in a preset region by using the mask aligning markers on the mask, and exposing the quadrate wafer through the mask; and step C: performing alignment for the quadrate wafer during a second exposure process and subsequent exposure processes by using aligning markers on the quadrate wafer that are obtained during the first exposure process. The method may be easily and reliably performed to ensure intact dies at periphery of a quadrate wafer to be produced and thus render increased yield of chips.

Abstract: The present invention discloses a root key type pressure bearing mechanism in an anchor hole, a root key type anchor cable and an anchor hole grouting method. The pressure bearing mechanism includes a carrier, root keys and a tapered plug, a through hole is formed in the center of the tapered plug, a taper hole is formed in the center of the carrier, key holes are formed along a radial direction of the carrier with an inner wall of the taper hole as a starting point, the number of the key holes is the same as that of the root keys, the root keys and the key holes constitute sliding pairs, an outer wall of the tapered plug is adapted to the taper hole, the sum of the length of the root key and the radius of a position corresponding to the tapered plug is larger than the radius of the anchor hole, and the length of the root key is less than the radius of the anchor hole; and when the tapered plug is plugged into the taper hole, the head of the root key stretches into a rock mass of the anchor hole.

Abstract: The usage of a stem cell in preparation of a tooth-like structure is provided. And a culture medium, a method for preparing an epithelial-like cell, a kit for preparing an ameloblast, a method for preparing an ameloblast are also provided. Specifically, the culture medium comprises a basal medium, which is DMEM/F12 medium; N2 supplement; retinoic acid; and BMP-4.

Abstract: A control system of a full-automatic cold plasma seed processor comprises a human-machine interaction interface, a PLC, a transport module, a vacuum degree module, an ionization module, and an energy supply module. The human-machine interaction interface is in a communications connection with the PLC by using a serial port. The energy supply module supplies a power source required by another module in a system. The PLC controls a transport rate of seeds by using the transport module, controls, by using the vacuum degree module, the vacuum degree of the system to reach a dynamic balance, and at last, controls the ionization time and the ionization power by using the ionization module, so as to adapt to processing requirements of different seeds and achieve an optimal processing effect. The control system can automatically process seeds of various grains, and brings short processing time and low cost.

Abstract: Disclosed are a 2-aminopyrimidine compound and pharmaceutical composition and use thereof. The structure of the 2-aminopyrimidine compound is as represented by formula I, in the formula, R1, R2, R3, R4, R5, X, Y, Z, W, (i) being as defined in the specification and the claims. Such compounds effectively inhibit the growth of a variety of tumor cells and have inhibitory effects on EGFR and IGF1R protease, and can be used for preparing antineoplastic drugs and overcome the tolerance induced by the existing drugs such as gefitinib, erlotinib and the like. The compound has selectivity for tumors, in particular the wild-type non-small cell lung cancer and have good pharmacokinetic characteristics.

Abstract: A semiconductor device structure is provided. The semiconductor device includes a semiconductor substrate, a first device, and a second device. Each of the first and second devices includes a gate extending in a first direction, source/drain regions respectively formed on opposite first and second sides of the gate, dielectric spacers formed respectively on outer sidewalls of the gate on the first side and the second side, and conductive spacers serving contacts to the source/drain regions and formed respectively on outer sidewalls of the respective gate spacers. A second direction from the source/drain region on the first side to the source/drain region on the second side crosses the first direction.

Abstract: The present invention relates to a TDMA access method and device based on multiple access points. According to the problems that the existing method cannot simultaneously satisfy the demands of timeliness and reliability in actual industrial application and has low resource utilization rate, the present invention takes full consideration of the transmission characteristics and industrial automation application characteristics of wireless networks, and provides a TDMA access method and device based on multiple access points.

Abstract: The present disclosure relates to the technical field of information data storage and processing. There is provided a method for regulating magnetic multi-domain state, comprising: when a current is applied to a magnetic thin film, applying an additional external magnetic field having a magnetic field strength of 0 to 4×105 A/m to regulate magnetization state of the magnetic thin film; wherein the current is configured to drive movements of a magnetic domain of the magnetic multi-domain states in the magnetic thin film, and the external magnetic field is configured to regulate generation of new magnetic domain in the magnetic thin film and state of the magnetic domain during the movement, so that the magnetic thin film is in a stable magnetic multi-domain state. Such a multi-domain state can't be affected by a higher or lower current and keeps stable when the current is removed.

Abstract: The present invention discloses a wafer-level semiconductor device and a manufacturing method thereof. The wafer-level semiconductor device comprises a wafer-level substrate; a plurality of serial groups formed on a surface of the substrate and are disposed in parallel, each serial group comprising a plurality of parallel groups disposed in series, each parallel groups comprising a plurality of unit cells disposed in parallel, wherein each unit cell is an independent functional unit which is formed by processing a semiconductor layer directly grown on a surface of the substrate; and a lead, which is at least electrically connected between two selected parallel groups in each serial group to make ON-voltages of all the serial groups substantially consistent. The device of the present invention, with a simple structure, a simple and convenient manufacturing process, and a high efficiency to produce qualified products, can be put into large-scale production and application.

Abstract: A high-sensitivity terahertz micro-fluidic channel sensor and a preparation method thereof. The sensor includes a substrate and a cover layer, respectively provided with a metal plane reflector and a metal microstructure layer; a micro-fluidic channel is formed between the metal plane reflector and the metal microstructure layer; and when the micro-fluidic channel tests liquid, a composite structure formed of the metal microstructure layer, the test liquid and the metal plane reflector shows good absorption properties. The method includes forming a metal plane reflector and a metal microstructure layer on a substrate and a cover layer, respectively; fixedly connecting the substrate to the cover layer, and forming a closed micro-fluidic channel between the substrate and the cover layer; and forming a through via, communicated to the micro-fluidic channel, on the substrate and/or the cover layer, to form a flow channel for transferring liquid to be tested to or from the sensor.

Abstract: A semiconductor arrangement and a method for manufacturing the same. An arrangement may include a bulk semiconductor substrate; a fin formed on the substrate; a first FinFET and a second FinFET formed on the substrate. The first FinFET comprises a first gate stack intersecting the fin and a first gate spacer disposed on sidewalls of the first gate stack. The second FinFET includes a second gate stack intersecting the fin and a second gate spacer disposed on sidewalls of the second gate stack; a dummy gate spacer formed between the first FinFET and the second FinFET and intersecting the fin; an isolation section self-aligned to a space defined by the dummy gate spacer. The isolation section electrically isolates the first FinFET from the second FinFET; and an insulation layer disposed under and abutting the isolation section.

Abstract: The present invention provides an indazole compound as a FGFR kinase inhibitor, preparation and use thereof. Specifically, the present invention provides a compound represented by formula (I), wherein the definitions of each group are described in the specification. The compound of the present invention has good FGFR kinase-inhibiting activity, and can be used in preparing a series of medicines for treating FGFR kinase activity related diseases.

Abstract: A method for realistic and real-time rendering of complex scene in internet environment, comprising: generating sequences of scene-object-multi-resolution models, a scene configuration file, textures and material files, and a scene data list file; compressing the sequences of scene-object-multi-resolution models, the scene configuration file, the textures and material files, and the scene data list file and uploading the compressed files to a server; downloading, at a client terminal, the scene-object-multi-resolution models, the scene configuration file, the texture and material file, and the scene data list file in ascending order of resolution and rendering the scene simultaneously; dividing, in rendering the scene, a frustum in parallel into a plurality of partitions, generating a shadow map for each frustum, filtering the shadow maps to obtain an anti-aliasing shadowing effect; and the shadow map closest to a viewpoint is updated on a frame-by-frame basis and updating frequency decreases for the shadow m

Abstract: A potassium fluoroboratoberyllate crystal oblique-incidence laser frequency multiplier, comprising: a flake-like potassium fluoroboratoberyllate crystal having parallel front and back polished surfaces; a front antireflection film and a back antireflection film; a columnar crystal support provided with a square holding slot and a light through-hole; and external heating jackets; the crystal is disposed in the square holding slot, the front and back surfaces of the crystal conforming to a main surface of the square holding slot, a normal of the main surface of the holding slot forming an angle ? with the central axis of the crystal support; a laser at a fundamental frequency passes through the front antireflection film, and a frequency-multiplied laser generated in the crystal is transmitted out through the back antireflection film. The present invention has a simple structure and a low cost, and is suitable for medium- and high-power laser systems.

Abstract: There is provided a method for manufacturing a semiconductor device, including: providing a semiconductor substrate having a plurality of openings formed thereon by removing a sacrificial gate; filling the openings with a top metal layer having compressive stress; and performing amorphous doping with respect to the top metal layer in a PMOS device region. Thus, it is possible to effectively improve carrier mobility of an NMOS device, and also to reduce the compressive stress in the PMOS device region to ensure a desired performance of the PMOS device.

Abstract: The present invention discloses deuterated benzopyran compounds having structure features as shown in Formula (I), or pharmaceutically acceptable salts or stereoisomers thereof, or prodrug molecules thereof. With excellent anti-inflammatory and analgesic effects and the capability to inhibit growth of tumor cells, such compounds are novel COX-2 selective inhibitors. The compounds and pharmaceutically acceptable salts thereof disclosed by the present application can be applied in preparing anti-inflammatory and analgesic drugs and drugs for treating or preventing tumors.

Abstract: The present invention provides a circulating fluidized bed boiler, comprising: furnace side walls; a ceiling; an air distribution plate provided at a bottom of a furnace; and at least one air distribution cone provided on the air distribution plate, wherein each air distribution cone extends upwards from the air distribution plate into an interior of the furnace and has a shape gradually tapered in an extending direction, cone side walls which form the air distribution cone are provided with secondary air ports, the cone side walls are separated from the furnace side walls, and a furnace combustion space is formed and surrounded by the ceiling, the furnace side walls, the air distribution plate, and the cone side walls.

Abstract: An optical vacuum cooling cryostage for correlative light and electron microscopy comprises a vacuum chamber, an anti-contamination system adapter interface, an electron microscope specimen holder adapter interface, an upper optical window, a lower optical window, a vacuum pumping system adapter interface and a vacuum valve, wherein the anti-contamination system adapter interface is arranged in one end of the vacuum chamber, the electron microscope specimen holder adapter interface is arranged in the other end of the vacuum chamber, the upper optical window is arranged on the upper wall of the vacuum chamber, the lower optical window is arranged on the lower wall of the vacuum chamber and opposite to the upper optical window.

Abstract: A method for preparation of an organohalosilane represented by formula I is disclosed. The method comprises: contacting an alcohol with metal sodium to yield a sodium alcoholate; contacting the sodium alcoholate with a halogen silane compound for an etherification reaction; and adding dropwise a fluorinating agent for a fluorination reaction. The organohalosilane is used for preparation of an electrolyte solution of a non-aqueous lithium ion battery.