Patents Assigned to Chinese Academy of Sciences
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Patent number: 9944901Abstract: Provided is a protein coded by a gene related to cell totipotency and a transcriptional activation domain of a mammalian YAP protein or a fusion protein of a segment with a transcriptional control activity, a coding nucleotide sequence, an expression vector and a composition thereof, as well as a method for inducing the pluripotent stem cells by using the fusion protein.Type: GrantFiled: June 17, 2014Date of Patent: April 17, 2018Assignees: Institute of Zoology, Chinese Academy of Sciences, Emory University School of MedicineInventors: Dahua Chen, Peng Jin, Qinmiao Sun, Weiqi Tan
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Patent number: 9944588Abstract: A method for preparing methyl formate in which a raw material containing formaldehyde, methanol and/or dimethyl ether is introduced into a first reaction zone to come into contact with a catalyst A, and a component I is obtained by separation, the component I is introduced into a second reaction zone to come into contact with a catalyst B so as to obtain, by separation, methyl formate as a product, dimethyl ether that is returned to the first reaction zone and a component II that is returned to the second reaction zone, the catalysts have a long service life, the reaction conditions are mild, and the utilization rate of the raw material is high, thus enabling a continuous production for large-scale industrial application.Type: GrantFiled: November 17, 2014Date of Patent: April 17, 2018Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCESInventors: Youming Ni, Wenliang Zhu, Yong Liu, Hongchao Liu, Zhongmin Liu, Lina Li, Shiping Liu, Hui Zhou
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Patent number: 9945399Abstract: The present invention discloses a liquid-driven nano-porous actuator and the application thereof, and belongs to the field of nano material actuators. According to the present invention, by changing the content of the liquid in the nano-porous material, the interface between the surface liquid of the nano-porous material and air is exchanged between flat and curved states, so as to change the compressive stress acting on the nano-porous material from the surface tension of the liquid and change the elastic deformation of the nano-porous material, thus driving the nano-porous material to contract and expand in a reversible manner and further realizing driving performance.Type: GrantFiled: September 26, 2014Date of Patent: April 17, 2018Assignee: INSTITUTE OF METAL RESEARCH, CHINESE ACADEMY OF SCIENCESInventors: Xinglong Ye, Lingzhi Liu, Haijun Jin
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Patent number: 9944587Abstract: A process for vapor-phase carbonylation of methanol to methyl formate, whereby a feed gas containing methanol, carbon monoxide, hydrogen and oxygen is passed through a reactor loaded with a supported nano-scaled platinum group metal heterogeneous catalyst to produce methyl formate by a vapor-phase carbonylation reaction, under reaction conditions with a space velocity of 500-5000 h?1, a temperature of 50-150° C. and a pressure of 0.01-2 MPa. Supported nano-scaled platinum group metal heterogeneous catalysts are prepared via ultrasonic dispersion and calcination. Methyl formate is produced and isolated under relatively mild conditions.Type: GrantFiled: June 12, 2014Date of Patent: April 17, 2018Assignee: FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCESInventors: Zhongning Xu, Guocong Guo, Siyan Peng, Zhiqiao Wang, Qingsong Chen, Mingsheng Wang, Yuangen Yao
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Patent number: 9941892Abstract: The present disclosure discloses a multi-standard performance reconfigurable I/Q orthogonal carrier generator. The generator may implement a continuously covered I/Q carrier output of 0.1-5 GHz and continuously covered differential signal outputs of 5-10 GHz and 1.5-3 GHz by means of reasonable frequency assignment; also, carrier signals under various frequencies with different loop bandwidths, different phase noises, different power consumption levels and different locking times can be generated by configuring a programmable charge pump (102), a loop filter (103) parameter, a multi-path voltage-controlled oscillator (104) and a first multiplexer (105) corresponding thereto, a five-stage-division-by-two frequency division link (109) and a corresponding second multiplexer (110) and third multiplexer (112), so as to implement generation of a multi-standard performance reconfigurable I/Q orthogonal carrier.Type: GrantFiled: June 24, 2014Date of Patent: April 10, 2018Assignee: Institute Of Semiconductors, Chinese Academy Of SciencesInventors: Xiaodong Liu, Nanjian Wu, Haiyong Wang, Wenfeng Lou, Jingjing Chen, Zhao Zhang
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Patent number: 9936654Abstract: The invention discloses a Dendrobium in vitro crossbreeding method. The method can be used to greatly shorten the maturation period of fruits, to enable a hybrid to bloom in vitro in a short period so as to observe flower shapes and colors, and to cultivate a novel variety, thus accelerating Dendrobium breeding, the first such report internationally. Since in vitro Dendrobium blooms annually, it enables crossbreeding of varieties having different inflorescences in nature. In addition, the medium used at each stage of the invention utilizes Hyponex which has a unique composition and costs little, thus allowing for a high blossoming rate and rapid fruit development. Also, only simple plant tissue culture equipment is required for implementing the invention, thus the entire breeding method is simple and low cost, and provides conditions for cultivating of high-quality Dendrobium varieties.Type: GrantFiled: July 19, 2013Date of Patent: April 10, 2018Assignee: SOUTH CHINA BOTANICAL GARDEN, CHINESE ACADEMY OF SCIENCESInventors: Songjun Zeng, Kunlin Wu, Jianxia Zhang, Feng Zheng, Jun Duan
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Patent number: 9938227Abstract: Method for preparing methyl formate and coproducing dimethyl ether by reacting a formaldehyde and methanol raw material (molar ratio range of 1:4 to 1:0.05) in a First Reaction Region at ranges from 50° C. to 100° C. with Catalyst A resulting in post-reaction material separated into Constituent I. Reacting Constituent I in a Second Reaction Region at ranges from 50° C. to 200° C. and from 0.1 MPa to 10 MPa with Catalyst B resulting in post-reaction material, which is separated into methyl formate, dimethyl ether and Constituent II. At least 1% of dimethyl ether is product, and recycling the rest to the First Reaction Region. Constituent II is recycled to the Second Reaction Region. Each component is gaseous phase and/or liquid phase, independently. The method shows long catalyst life, mild reaction condition, high utilization ratio of raw materials, continuous production and large scale industrial application potential.Type: GrantFiled: November 17, 2014Date of Patent: April 10, 2018Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCESInventors: Youming Ni, Wenliang Zhu, Yong Liu, Hongchao Liu, Zhongmin Liu, Lina Li, Shiping Liu, Hui Zhou
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Publication number: 20180098412Abstract: An undulator comprises at least M permanent magnet periods arranged sequentially in a transmission direction of electron beams, each of the permanent magnet periods comprises four rows of permanent magnet structures, in which each row comprises N rows of permanent magnet groups, and each row of the permanent magnet groups comprises K permanent magnet units, wherein M, N and K are natural numbers greater than or equal to 1; the four rows of the permanent magnet structures are pairwise matched, then relatively disposed on both sides of the transmission direction of electron beams, and are capable of forming at least one composite magnetic fields by relative displacement, such that elliptically polarized light, circularly polarized light, or linearly polarized light with an arbitrary polarization angle of 0°˜360° is generated when electron beams pass through the composite magnetic fields, and such that velocity directions of electrons are deviated from an axis direction of the undulator.Type: ApplicationFiled: November 13, 2015Publication date: April 5, 2018Applicant: SHANGHAI INSTITUTE OF MICROSYSTEM AND INFORMATION TECHNOLOGY, CHINESE ACADEMY OF SCIENCEInventors: SHAN QIAO, RUI CHANG, FUHAO JI, MAO YE
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Patent number: 9934975Abstract: An N-type MOSFET and a method for manufacturing the same are disclosed. In one aspect, the method comprises forming source/drain regions in a semiconductor substrate. The method also includes forming an interfacial oxide layer on the semiconductor substrate. The method also includes forming a high-k gate dielectric layer on the interfacial oxide layer. The method also includes forming a first metal gate layer on the high-k gate dielectric layer. The method also includes implanting dopants into the first metal gate layer through conformal doping. The method also includes annealing a gate stack to change an effective work function of the gate stack which includes the first metal gate layer, the high-k gate dielectric, and the interfacial oxide layer.Type: GrantFiled: September 23, 2014Date of Patent: April 3, 2018Assignee: Institute of Microelectronics, Chinese Academy of SciencesInventors: Huilong Zhu, Qiuxia Xu, Yanbo Zhang, Hong Yang
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Patent number: 9932280Abstract: Provided is a method for the preparation of a metal lattice-doping catalyst in an amorphous molten state, and the process of catalyzing methane to make olefins, aromatics, and hydrogen using the catalyst under oxygen-free, continuous flowing conditions. Such a process has little coke deposition and realizes atom-economic conversion. Under the conditions encountered in a fixed bed reactor (i.e. reaction temperature: 750˜1200° C.; reaction pressure: atmospheric pressure; the weight hourly space velocity of feed gas: 1000˜30000 ml/g/h; and fixed bed), conversion of methane is 8-50%. The selectivity of olefins is 30˜90%. And selectivity of aromatics is 10˜70%. There is no coking. The reaction process has many advantages, including a long catalyst life (>100 hrs), high stability of redox and hydrothermal properties under high temperature, high selectivity towards target products, zero coke deposition, easy separation of products, good reproducibility, safe and reliable operation, etc.Type: GrantFiled: July 24, 2013Date of Patent: April 3, 2018Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCESInventors: Xinhe Bao, Xiaoguang Guo, Guangzong Fang, Dehui Deng, Hao Ma, Dali Tan
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Publication number: 20180091371Abstract: A multi-terminal interaction relation maintenance system and method, the interaction relation is states of performing instruction and data synchronization interaction by a plurality of terminals in the same service instance in a traffic service system. The system comprises an interaction service module and an interaction terminal. Terminals that have an interaction relation belong to the same bounding group, terminals in the same bounding group are served by the same service instance, the interaction service module manages the bounding group based on rules, comprising but not limited to creating, modifying and deleting the bounding group, provides a mutual addressing service for the terminals in the bounding group and also provides a service for a terminal to be bound or unbound with other terminals, and after mutually addressing by means of the interaction service module, terminals interact with each other by means of instruction and data interaction.Type: ApplicationFiled: June 4, 2015Publication date: March 29, 2018Applicants: INSTITUTE OF ACOUSTICS, CHINESE ACADEMY OF SCIENCES, SHANGHAI 3NTV NETWORK TECHNOLOGY CO. LTD.Inventors: Zhongzhen YANG, Jinlin WANG, Xue LIU, Shoujiang DANG, Liheng TUO
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Publication number: 20180087120Abstract: The present invention relates to method and apparatus for treating iron-contained raw material using bath smelting furnace. An iron-contained raw material is mixed with a reducing agent. The mixture is added into a bath smelting furnace. The enriched oxygen is blown into the bath. The smelt is conducted at a temperature of 1200-1600° C. Compared with the traditional process of “sintering/pellet-blast furnace smelting” or “rotary furnace reduction-electrical furnace smelting separation”, the present invention has the remarkable advantages of short process, strong raw material adaptability, high product quality, low energy consumption, low pollution, etc. The present invention provides a new technology direction for effectively and comprehensively utilizing the iron-contained resource and has a wide application prospect.Type: ApplicationFiled: September 27, 2017Publication date: March 29, 2018Applicant: Institute of Process Engineering, Chinese Academy of SciencesInventors: Tao Qi, Lingyun Yi, Desheng Chen, Lina Wang, Hongxin Zhao, Yahui Liu, Weijing Wang, Hongdong Yu
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Publication number: 20180087945Abstract: A new experimental device for debris flow simulation, including a material supply device, a flow channel, a stacking groove, a pole, a first high-speed camera, a second high-speed camera, a fixing frame, and a sliding rail. The material supply device is used to release the debris flow simulation material to the flow channel, to realize the start of the debris flow simulation. The stacking groove is used for the accumulation of the debris flow. The pole is used to support the stacking groove and adjust the slope of the stacking groove. The fixing frame is used to fix the first high-speed camera. The second high-speed camera can monitor the movement of the debris flow. The invention can flexibly simulate the movement characteristics of various debris flow and obtain the test data, so as to provide data support for the subsequent study.Type: ApplicationFiled: September 18, 2017Publication date: March 29, 2018Applicant: Institute of Mountain Hazards and Environment, Chinese Academy of SciencesInventors: Yuanjun JIANG, Siyou XIAO, Yue SONG, Zhen JIANG, Meng WANG
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Patent number: 9927675Abstract: A terahertz modulator based on low-dimension electron plasma wave, a manufacturing method thereof, and a high speed modulation method are provided. The terahertz modulator includes a plasmon and a cavity. The present disclosure discloses the resonance absorption mechanism caused by collective oscillation of electrons (plasma wave, namely, the plasmon). In order to enhance the coupling strength between the terahertz wave and the plasmon, a GaN/AlGaN high electron mobility transistor structure having a grating gate is integrated in a terahertz Fabry-Pérot cavity, and a plasmon polariton is formed arising from strong coupling of the plasmon and a cavity mode.Type: GrantFiled: June 9, 2015Date of Patent: March 27, 2018Assignee: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS (SINANO), CHINESE ACADEMY OF SCIENCESInventors: Yongdan Huang, Hua Qin, Zhipeng Zhang, Yao Yu
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Patent number: 9926618Abstract: The present invention discloses an extracting agent for separating lithium isotopes and an organic extraction phase containing the extracting agent; the organic extraction phase easily enriches 7Li and achieves the separation of lithium isotopes. The present invention also discloses a high-efficiency method for separating lithium isotopes in an aqueous solution, in which the organic extraction phase of the present invention is used, said organic extraction phase being suitable for single-stage and multi-stage extraction processes.Type: GrantFiled: May 8, 2013Date of Patent: March 27, 2018Assignee: Shanghai Institute of Organic Chemistry, Chinese Academy of SciencesInventors: Beili Li, Huaiyu Sheng, Jinbo Hu
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Patent number: 9926251Abstract: This invention discloses an approach for the separation of the close-boiling mixture of polyols. The raw material is ethylene glycol containing miscellaneous polyols (such as 1,2-propylene glycol and 1,2-butanediol). Over an acid catalyst, these miscellaneous polyols, through (1) a dehydration reaction, (2) pinacol rearrangement, and (3) acetalization or ketalization reaction, are converted into aldehydes (small amounts), acetals, and ketals (trace amount), which are simultaneously and readily separated via distillation. Meanwhile, after the reaction, the mixture is further separated to obtain an ethylene glycol product at a high purity. The invention provides a technique to remove the miscellaneous polyols from ethylene glycol via liquid-phase dehydration reactions under mild conditions, with low energy consumption. In particular, this approach is markedly effective for the removal of 1,2-butanediol that is difficult to be removed via conventional techniques.Type: GrantFiled: November 26, 2015Date of Patent: March 27, 2018Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCESInventors: Tao Zhang, Shuo Al, Mingyuan Zheng, Aiqin Wang, Weizhen Li, Xiaodong Wang
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Patent number: 9930284Abstract: The present disclosure provides an analog readout preprocessing circuit for a CMOS image sensor and a control method thereof. The analog readout preprocessing circuit comprises an extended count-type integration cycle-successive approximation hybrid analog-to-digital conversion capacitor network 1 configured to achieve readout and analog-to-digital conversion of signals output from the CMOS image sensor; an operational amplifier configured to utilize “virtual short” of two input terminals of the operational amplifier and the charge conservation principle, to achieve a function of extended count-type integration cycle-successive approximation hybrid analog-to-digital conversion, where the extended count-type integration can effectively reduce a thermal noise and a flicker noise within the image sensor; a comparator configured to compare voltages at two terminals to achieve a function of quantization of signals; and a control signal generator configured to provide control signals.Type: GrantFiled: December 29, 2014Date of Patent: March 27, 2018Assignee: INSTITUTE OF SEMICONDUCTORS, CHINESE ACADEMY OF SCIENCESInventors: Liyuan Liu, Nanjian Wu, Zhiqiang Guo
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Publication number: 20180073035Abstract: Provided is a method for conducting site-specific modification in a plant through gene transient expression, comprising the following steps: transiently expressing a sequence-specific nuclease specific to the target fragment in the cell or tissue of the plant of interest, wherein the sequence-specific nuclease is specific to the target site and the target site is cleaved by the nuclease, thereby the site-specific modification of the target site is achieved through DNA repairing of the plant.Type: ApplicationFiled: January 19, 2016Publication date: March 15, 2018Applicant: Institute of Genetics and Developmental Biology, Chinese Academy of SciencesInventors: Caixia Gao, Yanpeng Wang, Yi Zhang, Jinxing Liu, Kang Zhang
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Patent number: 9917301Abstract: Described herein are solid solution composites that are used as cathode materials for lithium-ion batteries. The solid solution composite of ? LiMVO4-?LiNi1-x-yCoxMnyO2, in which LiMVO4 has cubic close-packed structure, LiNi1-x-yCoxMnyO2 has hexagonal layered structure, and both share an oxygen lattice fully or partly. The new solid solution materials have advantage for lithium-ion batteries that the working voltage of the composite is adjustable by controlling the molar ratio of ? and ? and have higher working voltage than current secondary battery materials. Also described herein are methods of preparing such composite.Type: GrantFiled: August 1, 2012Date of Patent: March 13, 2018Assignees: NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING CHINESE ACADEMY OF SCIENCES, GUANGDONG KEPRIME ENERSTORE LTDInventors: Jun Li, Jinhua He, Zhenlian Chen, Xianhui Zhang, Yuanhao Tang, Deyu Wang
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Patent number: 9914707Abstract: The present invention relates to a naphthylamide compound of the structure as represented by formula (I), medicinal salts, prodrugs and hydrates or solvates thereof, and also relates to a method of preparing the compounds, pharmaceutical compositions comprising the compounds and the uses thereof as protein tyrosine kinase inhibitors, particularly as VEGFR-2 inhibitors, in preparing drugs for preventing and treating diseases related to abnormal angiogenesis.Type: GrantFiled: February 15, 2015Date of Patent: March 13, 2018Assignee: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCESInventors: Wenhu Duan, Jian Ding, Yongcong Lv, Hua Xie