Patents Assigned to CHR. Hansen
  • Publication number: 20240166989
    Abstract: The present invention relates to a novel Streptococcus thermophilus strain having improved texturizing properties, compositions comprising said strain as well as fermented products manufactured using said strain.
    Type: Application
    Filed: January 6, 2022
    Publication date: May 23, 2024
    Applicant: Chr. Hansen A/S
    Inventors: Thomas Janzen, Ditte Christiansen, Jesper Broend, Victoria Prebner, Ilenia Manuguerra, Geoffrey Ras
  • Patent number: 11981947
    Abstract: The present invention relates to the use of one or more glycosidases in the process for the production and/or purification of a produced desired oligosaccharide. The process is preferably a microbial fermentation process using a host microorganism, which may also comprise nucleic acids expressing sugar catabolic pathway proteins suitable for the degradation of saccharides otherwise hindering the purification of the desired oligosaccharide.
    Type: Grant
    Filed: July 22, 2022
    Date of Patent: May 14, 2024
    Assignee: Chr. Hansen HMO GmbH
    Inventor: Stefan Jennewein
  • Patent number: 11981890
    Abstract: Microbial starter cultures. More specifically, a method for preparing a microbial culture such as a lactic acid bacteria (LAB) starter culture wherein at least one microbial strain such as a lactic acid bacteria and at least one inactivated yeast strain is inoculated in a culture medium.
    Type: Grant
    Filed: December 10, 2020
    Date of Patent: May 14, 2024
    Assignee: Chr. Hansen A/S
    Inventors: Neda Faraghiparapari, Marie Penderup Jensen, Jakub Kovacs, Anisha Goel
  • Publication number: 20240150706
    Abstract: The present invention relates to microencapsulated microbial cultures with high storage stability and methods for producing these. In particular, the present invention relates to microbial cultures formulated at high ratios of encapsulation matrix material to core material.
    Type: Application
    Filed: February 10, 2022
    Publication date: May 9, 2024
    Applicant: Chr. Hansen A/S
    Inventors: Deepak Jain, Surender Kumar Dhayal
  • Publication number: 20240141282
    Abstract: The present invention provides a process for spray freezing or spray freeze drying under conditions of very low oxygen pressure, such as under essentially anaerobic conditions, and particularly a process for spray freezing strict anaerobic microorganisms (bacteria) under conditions where the level of oxygen is very low, or essentially anaerobic. Further, the invention provides a product achievable by the processes and an apparatus usable in the process.
    Type: Application
    Filed: February 25, 2021
    Publication date: May 2, 2024
    Applicant: Chr. Hansen A/S
    Inventors: Michelle Milling Madsen, Kim Nielsen, Jimi Kjaersgaard Pettersson, Wendy Ossieur
  • Publication number: 20240130384
    Abstract: The present invention relates to a composition comprising one or more novel Streptococcus thermophilus strain(s), and the use of said composition for producing a fermented product such as a dairy product with e.g. an increased sweetness. The invention also relates to novel Streptococcus thermophilus strain(s) as such.
    Type: Application
    Filed: February 23, 2022
    Publication date: April 25, 2024
    Applicant: Chr. Hansen A/S
    Inventors: Jesper BROEND, Sonja BLOCH, Kim Ib SOERENSEN
  • Publication number: 20240132832
    Abstract: The present invention relates to the field of frozen or dry compositions for prokaryotes, in particular fermentative bacteria such as lactic acid bacteria, a method for preparing frozen or dry prokaryotic compositions and compositions which may be prepared by said method. The cells in a cell concentrate are activated by allowing them to ferment a carbohydrate, before freezing and/or drying to provide a product. The hydrophobicity of the cell surface increases during activation, and this has been found to increase the storage stability of the product.
    Type: Application
    Filed: November 29, 2021
    Publication date: April 25, 2024
    Applicant: Chr. Hansen A/S
    Inventors: Zuzana Mladenovska, Surender Kumar Dhayal, Kim Nielsen
  • Publication number: 20240110213
    Abstract: Disclosed are genetically engineered microbial cells for the production of an oligosaccharide of interest, wherein said microbial cells possess a variant of the E. coli lactose permease LacY which exhibits a reduced transport activity for lactose, and methods for producing an oligosaccharide by using said genetically engineered microbial cells.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 4, 2024
    Applicant: Chr. Hansen HMO GmbH
    Inventors: Henning Frerigmann, Christian Trötschel, Dirk Wartenberg, Stefan Jennewein
  • Publication number: 20240084281
    Abstract: Variants of chymosin with improved milk-clotting properties are disclosed.
    Type: Application
    Filed: October 30, 2023
    Publication date: March 14, 2024
    Applicant: Chr. Hansen A/S
    Inventors: Johannes Maarten van den Brink, Jesper Langholm Jensen, Jonas Jacobsen, Martin Lund, Iben Jeppesen, Christian Jaeckel
  • Patent number: 11920173
    Abstract: Disclosed are non-naturally-occurring microorganisms for the production of N-acetylneuraminic acid, a method for the production of N-acetylneuraminic acid by fermentation of the non-naturally-occurring microorganisms, and nutritional compositions containing N-acetylneuraminic acid which has been produced by fermentation of the non-naturally-occurring microorganisms.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: March 5, 2024
    Assignee: Chr Hansen HMO GmbH
    Inventors: Stefan Jennewein, Dirk Wartenberg
  • Patent number: 11912735
    Abstract: Disclosed is a method for purifying sialylated oligosaccharides from a fermentation broth, cell-lysate or biocatalytic reaction mixture for obtaining high amounts of desired sialylated oligosaccharides in high purity. The method is particular suitable for the large-scale economic purification of sialylated human milk oligosaccharides (such as 3?-sialyllactose, 6?-sialyllactose or sialylated lacto-N-tetraose derivatives) from microbial fermentation, using recombinant bacterial cells or yeast cells. The obtained material is of high purity and can be used for food or medical application such like medical nutrition products, infant formula, dietary supplements, general nutrition products (e.g. dairy drinks).
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: February 27, 2024
    Assignee: Chr Hansen HMO GmbH
    Inventors: Stefan Jennewein, Markus Helfrich, Benedikt Engels
  • Publication number: 20240052324
    Abstract: Disclosed are enzymes, compositions, genetically engineered cells and methods for the fermentative production of 6?-sialyllactose.
    Type: Application
    Filed: December 22, 2020
    Publication date: February 15, 2024
    Applicant: Chr. Hansen HMO GmbH
    Inventors: Stefan Jennewein, Dirk Wartenberg
  • Patent number: 11896022
    Abstract: The present invention relates to a process for making low-moisture mozzarella cheese using recent developments in the technical knowledge about the interactions between cultures, coagulants and cheese technology to increase cheese yields and maintain the cheese quality and functionalities. An optimization may lead to a higher pH and higher dry matter of the curd at the whey off step i.e. pH higher than 6.3 and ideally higher than 6.4 and solid non-fact content higher than 18%, without any modification of the curd composition at the stretching step, i.e. pH between 5.0 and 5.3 and more precisely between without any modification of the curd composition at the stretching step, i.e. pH between 5.0 and 5.3 and more precisely between 5.05 and 5.25, Ca/SNF between 1.7% and 2.4% and more precisely between 1.7 and 2.2%, dry matter between 53% and 55% and more precisely between 53.5% and 54.5%. The coagulant has a C/P ratio of at least 25.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: February 13, 2024
    Assignee: Chr. Hansen A/S
    Inventors: Sebastien Roustel, Véronique Jactat, Ulf Mortensen, Viviana Ester Bruno, Michael Mitsuo Saito
  • Patent number: 11898185
    Abstract: The present invention relates to a method for producing fucosylated oligosaccharides by using a recombinant prokaryotic host cell that is cultivated on a gluconeogenic substrate, as well as to the host cell and its use. The host cell is genetically modified in that the activity of a fructose-6-phosphate converting enzyme is abolished or lowered, and the transport of the produced fucosylated oligosaccharide through the cell membrane is facilitated by an exogenous transport protein.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: February 13, 2024
    Assignee: Chr Hansen HMO GmbH
    Inventors: Stefan Jennewein, Dirk Wartenberg, Katja Parschat
  • Publication number: 20240023568
    Abstract: The present invention relates to encapsulation of microbial cultures to improve the robustness and stability upon storage. In particular, the present invention relates to dry preparations of microbial cultures, such as lactic acid bacteria (LAB), coated by a fat-matrix that increase survivability and mitigate post-acidification upon storage at ambient temperature for extended periods of time.
    Type: Application
    Filed: November 29, 2021
    Publication date: January 25, 2024
    Applicant: Chr. Hansen A/S
    Inventors: Surender Kumar Dhayal, Anisha Goel, Simranjeet Tiwana
  • Publication number: 20240026281
    Abstract: Present invention relates to dried lactic acid bacteria compositions are stabilised with synergistic mixtures of stabilisers selected from oligofructans, maltodextrin, inulin and pea fibre. The mixtures have been found to stabilise the compositions during the drying (e.g. freeze-drying) process and during storage.
    Type: Application
    Filed: November 29, 2021
    Publication date: January 25, 2024
    Applicant: Chr. Hansen A/S
    Inventors: Furqan Ali, Surender Kumar Dhayal
  • Publication number: 20240026403
    Abstract: The present invention concerns an efficient way to isolate L-fucose from a fermentation broth. The L-fucose contained in the fermentation broth is produced by microbial fermentation (bacterial or yeasts). The inventive process comprises a step of removing biomass from the fermentation broth, a step of subjecting the resulting solution to at least one of a cationic ion exchanger treatment and an anionic ion exchanger treatment and a step of removing salts after the ion exchanger treatment. The process can provide L-fucose in powder form, in granulated form as well as in form of L-fucose crystals.
    Type: Application
    Filed: June 29, 2023
    Publication date: January 25, 2024
    Applicant: Chr. Hansen HMO GmbH
    Inventors: Markus Helfrich, Stefan Jennewein
  • Publication number: 20240008502
    Abstract: The present invention relates to a novel Streptococcus thermophilus strain having improved texturizing properties, compositions comprising said strain as well as fermented products manufactured using said strain.
    Type: Application
    Filed: November 16, 2021
    Publication date: January 11, 2024
    Applicant: Chr. Hansen A/S
    Inventors: Thomas Janzen, Ditte Ellegaard Christiansen, Jesper Broend, Victoria Prebner
  • Patent number: 11856970
    Abstract: Described are the Bacillus subtilis strain deposited as DSM 32685 and mutant strains thereof which are susceptible to relevant antibiotics, have inhibitory activity against, for example, Staphylococcus, Streptococcus, E. coli and Salmonella, and have the ability to facilitate degradation of non-starch polysaccharides and thereby increase the amount of available oligosaccharides (sugar) in animal feed. Also described are compositions comprising at least one Bacillus subtilis strain of the disclosure and optionally further bacteria and/or one or more types of yeast and methods of using such compositions.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: January 2, 2024
    Assignee: Chr. Hansen A/S
    Inventors: Dorthe Sandvang, Ole Knudsmark Sjoeholm, Line Skjoet-Rasmussen, Jette Mundus Nielsen
  • Publication number: 20230416673
    Abstract: The present invention relates to a novel Streptococcus thermophilus strain having improved texturizing properties, compositions comprising said strain as well as fermented products manufactured using said strain.
    Type: Application
    Filed: November 16, 2021
    Publication date: December 28, 2023
    Applicant: Chr. Hansen A/S
    Inventors: Kim Ib Soerensen, Mette Pia Junge, Jesper Broend, Victoria Prebner