Patents Assigned to Cipla Limited
  • Publication number: 20090291143
    Abstract: A pharmaceutical product or formulation, which comprises azelastine or a pharmaceutically acceptable salt, solvate or physiologically functional derivative thereof, and a steroid, or a pharmaceutical acceptable salt, solvate or physiologically functional derivative thereof, preferably the product or formulation being in a form suitable for nasal or ocular administration.
    Type: Application
    Filed: July 23, 2009
    Publication date: November 26, 2009
    Applicant: CIPLA LIMITED
    Inventors: Amar Lulla, Geena Malhotra
  • Patent number: 7598387
    Abstract: A process of preparing rosiglitazone, or a pharmaceutically acceptable salt thereof, which process employs an intermediate metabisulphite complex of 4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzaldehyde, which metabisulphite complex is represented by following formula (III): where X represents an alkali metal. The present invention further provides rosiglitazone, or a pharmaceutically acceptable salt thereof, prepared by the above process.
    Type: Grant
    Filed: May 3, 2005
    Date of Patent: October 6, 2009
    Assignee: Cipla Limited
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan
  • Publication number: 20090221830
    Abstract: Anhydrous crystalline fexofenadine hydrochloride Form C, crystalline fexofenadine acetate monohydrate Form D, crystalline fexofenadine acetate dihydrate Form E and crystalline fexofenadine free base monohydrate Form F, processes of preparing the same, pharmaceutical compositions thereof, therapeutic uses thereof and methods of treatment therewith.
    Type: Application
    Filed: November 19, 2008
    Publication date: September 3, 2009
    Applicant: Cipla Limited
    Inventors: Dharmaraj Ramachandra RAO, Rajendra Narayanrao KANKAN, Manish Gopaldas GANGRADE, Dilip Ramdas BIRARI
  • Patent number: 7579505
    Abstract: The invention provides three polymorphic forms of crystalline levosalbutamol sulphate designated herein as Forms I, II and III. Crystalline levosalbutamol sulphate Form I is characterised by a powder XRD pattern with peaks at 10.8, 11.9, 13.0, 18.3, 28.5±0.2 degrees 2 theta. Crystalline levosalbutamol sulphate Form II is characterised by a powder XRD pattern with peaks at 8.7, 9.6, 15.2, 15.7, 19.1, 27.2, 30.7±0.2 degrees 2 theta. Crystalline levosalbutamol sulphate Form III is characterised by a powder XRD pattern with peaks at 5.5, 6.9, 7.3, 18.7±0.2 degrees 2 theta. Processes for making the new polymorphic forms and pharmaceutical compositions comprising them are also provided.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: August 25, 2009
    Assignee: CIPLA Limited
    Inventors: Dharmaraj Ramchandra Rao, Rajendra Narayanrao Kankan, Alka Chaudhary
  • Publication number: 20090187020
    Abstract: The invention relates to new compounds of formula (III): wherein R is a C1-C4 linear or branched alkyl group. The invention also relates to new compounds of formula (IV) wherein M is a metal. The invention also relates to methods of making compounds of formulas (III) and (IV) and to methods of making donepezil and pharmaceutically acceptable salts thereof, such as donepezil hydrochloride, using the compounds.
    Type: Application
    Filed: January 3, 2007
    Publication date: July 23, 2009
    Applicant: CIPLA LIMITED
    Inventors: Srinivas Laxminarayan Pathi, Vinod Acharya, Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan
  • Patent number: 7550593
    Abstract: A process of preparing finasteride Form (I), which process comprises dissolving finasteride in a solvent, replacing the solvent partially or substantially completely with a nonsolvent and thereafter isolating finasteride Form (I). There is also provided finasteride Form (I) prepared in accordance with the present invention, and the therapeutic use thereof in the inhibition of 5-alpha reductase, and pharmaceutical compositions containing the same.
    Type: Grant
    Filed: July 5, 2004
    Date of Patent: June 23, 2009
    Assignee: Cipla Limited
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao
  • Patent number: 7538249
    Abstract: Racemic tolterodine free base in crystalline form, tolterodine with improved purity, compositions and uses thereof, and processes of preparing the same.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: May 26, 2009
    Assignee: Cipla Limited
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao
  • Patent number: 7517519
    Abstract: The present invention is concerned with the use of at least one immunosuppressant, or a pharmaceutically acceptable salt, solvate of physiologically functional derivative thereof, in the treatment of topical immune disorders of the scalp, and scalp conditions, and compositions suitable for such use.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: April 14, 2009
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Geena Malhotra
  • Patent number: 7470789
    Abstract: Anhydrous crystalline fexofenadine hydrochloride Form C, crystalline fexofenadine acetate monohydrate Form D, crystalline fexofenadine acetate dihydrate Form E and crystalline fexofenadine free base monohydrate Form F, processes of preparing the same, pharmaceutical compositions thereof, therapeutic uses thereof and methods of treatment therewith.
    Type: Grant
    Filed: August 25, 2004
    Date of Patent: December 30, 2008
    Assignee: Cipla Limited
    Inventors: Dharmaraj Ramachandra Rao, Rajendra Narayanrao Kankan, Manish Gopaldas Gangrade, Dilip Ramdas Birari
  • Patent number: 7439367
    Abstract: The present invention relates to an improved process for the preparation of a sulfinyl compound of formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, from a sulfide compound of formula (II), wherein in both formulae (I) and (II) R1 and R3 are selected from the group consisting of hydrogen, methyl or C1-4alkoxy, R2 is selected from the group consisting of substituted or unsubstituted C1-4alkoxy and R4 is selected from the group consisting of hydrogen or substituted or unsubstituted C1-4alkoxy.
    Type: Grant
    Filed: January 12, 2004
    Date of Patent: October 21, 2008
    Assignee: CIPLA Limited
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao, Pathi L. Srinivas
  • Publication number: 20080234492
    Abstract: A process for the preparation of carvedilol of formula (I) (I) either in enantiomeric substantially pure form, or as an enantiomeric mixture, optionally as a pharmaceutically acceptable salt thereof, which process comprises reacting 2,3-eopxypropoxy carbazole of formula (II) (II) or the R or S enantiomer thereof, with N-[2-(2-methoxy-phenoxy)ethyl]-benzylamine of formula (V) (V) to yield benzyl carvedilol of formula (VI) (VI) which is debenzylated by catalytic hydrogenation to yield carvedilol of formula (I), either in enantiomeric substantially pure form, or as an enantiomeric mixture, and if desired reacting the thus formed carvedilol of formula (I) with an inorganic or organic acid to yield a pharmaceutically acceptable salt thereof, and/or, if desired, separating the enantiomers. The above process is characterised in that reaction of said 2,3-epoxypropoxy carbazole of formula (II) with said N-[2-(2-methoxy-phenoxy)ethyl]-benzylamine of formula (V) is carried out in water as the reaction medium.
    Type: Application
    Filed: May 19, 2005
    Publication date: September 25, 2008
    Applicant: CIPLA LIMITED
    Inventors: Rajendra Narayanrao Kankan, Dharmaraj Ramachandra Rao
  • Patent number: D577433
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: September 23, 2008
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Geena Malhotra
  • Patent number: D579958
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: November 4, 2008
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Xerxes Rao
  • Patent number: D590057
    Type: Grant
    Filed: November 29, 2006
    Date of Patent: April 7, 2009
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Geena Malhotra
  • Patent number: D590495
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: April 14, 2009
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Xerxes Rao
  • Patent number: D590938
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: April 21, 2009
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Xerxes Rao
  • Patent number: D590939
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: April 21, 2009
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Xerxes Rao
  • Patent number: D591855
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: May 5, 2009
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Xerxes Rao
  • Patent number: D591856
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: May 5, 2009
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Xerxes Rao
  • Patent number: D604831
    Type: Grant
    Filed: January 11, 2008
    Date of Patent: November 24, 2009
    Assignee: Cipla Limited
    Inventors: Amar Lulla, Xerxes Rao