Abstract: A microorganism of the genus Corynebacterium having the ability to produce inosine in which the inosine catabolic pathway is blocked and that has a leaky adenine auxotrophic phenotype and further has a leaky guanine auxotrophic phenotype and a method of producing inosine, the method including culturing the microorganism of the genus Corynebacterium are disclosed.
Type:
Grant
Filed:
January 2, 2009
Date of Patent:
October 8, 2013
Assignee:
CJ Cheiljedang Corp.
Inventors:
Chul Ha Kim, Jong Soo Choi, Jeong Hwan Kim, Hyoung Seok Kim, Jung Gun Kwon, Tae Min Ahn, Soo Youn Hwang, Jae Ick Sim, Min Ji Baek, Na Ra Kwon, Hye Jin Choi
Abstract: An L-threonine-producing Escherichia coli in which a promoter of a phosphoenolpyruvate carboxylase (ppc) gene on the chromosome is substituted with a promoter of a cysteine synthase (cysK) gene and a method of producing L-threonine by using the same are disclosed. The recombinant Escherichia coli may produce L-threonine in a high yield, and thus may be widely used in medical, pharmaceutical, and feed industries, particularly for an animal feed.
Type:
Grant
Filed:
January 7, 2009
Date of Patent:
June 4, 2013
Assignee:
CJ Cheiljedang Corp.
Inventors:
Kwang Ho Lee, Jae Yeong Ju, Ji Sun Lee, Young Bin Hwang, Sung Hoo Jhon, Eun Sung Koh, Chul Ha Kim, Soo An Shin
Abstract: The present invention relates to a microorganism of Corynebacterium ssp. having enhanced expression of gene for encoding molybdenum cofactor biosynthesis enzyme A and a method for producing L-lysine using the same, which has effects on providing the production method of L-lysine using the Corynebacterium strain having enhanced productivity of L-lysine by intensifying expression of the moaA gene for encoding molybdnum cofactor biosynthesis enzyme A.
Type:
Grant
Filed:
December 20, 2007
Date of Patent:
May 14, 2013
Assignee:
CJ Cheiljedang Corp.
Inventors:
Jun-Ok Moon, Jae-Woo Jang, So-Yeon Rah, Sang-Jo Lim, Jong-Soo Choi, Young-Hoon Park, Hyung-Joon Kim
Abstract: Provided are a novel promoter nucleic acid molecule having a nucleotide sequence of SEQ ID NO: 1 or 2 derived from Corynebacterium glutamicum, a recombinant vector comprising the promoter, a host cell transformed with the vector and a method of expressing genes of interest using the host cell.