Patents Assigned to Cleveland Biolabs, Inc.
  • Methods of protecting against apoptosis using lipopeptides
    Patent number: 8008260
    Abstract: The use of lipopeptides as inducers of NF-?B for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: June 13, 2006
    Date of Patent: August 30, 2011
    Assignees: Cleveland Clinic Foundation, Cleveland Biolabs, Inc.
    Inventors: Alexander Shakhov, Andrei Gudkov
  • METHODS FOR TREATING REPERFUSION INJURIES
    Publication number: 20110135665
    Abstract: The present invention relates to treating a tissue in a mammal from the effects of reperfusion using flagellin.
    Type: Application
    Filed: July 31, 2009
    Publication date: June 9, 2011
    Applicants: CLEVELAND BIOLABS, INC., CLEVELAND CLINIC FOUNDATION
    Inventors: Andrei Gudkov, Robert Fairchild
  • Modulating apoptosis
    Patent number: 7638485
    Abstract: The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-?B activity. The modulators may be used, for example, in the treatment of NF-?B-mediated diseases, conditions, and injuries.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: December 29, 2009
    Assignees: Cleveland Biolabs, Inc., Cleveland Clinic Foundation
    Inventor: Andrei V. Gudkov
  • METHODS FOR IDENTIFYING MODULATORS OF APOPTOSIS
    Publication number: 20070298974
    Abstract: Provided herein is a method for screening a modulator of apoptosis comprising the provision of a cell comprising major vault protein and a FAS mediated apoptosis and contacting the cell with a candidate modulator and measuring the level of apoptosis of the cell. The modulator of apoptosis is identified by a change in apoptosis in comparison to a control.
    Type: Application
    Filed: June 26, 2007
    Publication date: December 27, 2007
    Applicant: Cleveland Biolabs, Inc.
    Inventor: Andrei Gudkov