Abstract: Disclosed are therapeutic oral compositions useful in the treatment of a variety of oral disorders, in which the composition can provide blockage of dentinal tubes, while at the same time provide antibacterial and anti-caries efficacy. The compositions include arginine in free or salt form, a mucoadhesive polymer, and at least one component selected from pyrophosphates, zinc salts, potassium salts, strontium salts, and mixtures thereof.

Abstract: A toothpaste comprising at least 5% sodium chloride and a carrageenan-based binder, having high antibacterial efficacy, very stable viscosity and excellent striping properties, together with methods and uses therefore.

Abstract: The present invention is directed to a method for whitening teeth that includes irradiating a tooth with light generated by a light source for an irradiation time period, the light having a wavelength that ranges from 375 nm to 420 nm and the light source emitting the light at an irradiance density ranging from 0.3 mW/cm2 to 20.0 mW/cm2.

Abstract: The disclosure provides an improved synthesis for a zinc-lysine complex having the formula [Zn(C6H14N2O2)2Cl]+Cl?, in which zinc chloride is reacted with lysine, in aqueous solution. The disclosure also provides oral care and personal care compositions comprising the complex prepared by the synthesis, and methods of using these complexes and compositions.

Abstract: This application is directed to a fast method of quantitatively and qualitatively validating the amount of silicone adhesive in a composition comprising silicone adhesive and silicone polymer which comprises of testing a sample of the composition with near IR or mid IR spectroscopy. The method can be extended to analyzing the amount of silicone adhesive in an oral care composition.

Abstract: A tooth whitening system comprising a dental tray having a surface operable to confront a tooth surface, and a tooth whitening composition comprising a whitening agent and a hydrophobic. polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. A tooth whitening kit is also provided using a dental tray and the tooth whitening composition comprising a whitening composition and a hydrophobic polymer carrier.

Abstract: An in vitro method for determining the bioavailability of zinc (II) ions from an oral care composition comprises: providing a sample comprising, the oral care composition; contacting the sample with a biorelevant substrate, separating the biorelevant substrate from the sample, contacting the biorelevant substrate with an indicator under conditions selected such that the indicator is capable of reacting with zinc (II) ions, and determining a light absorbance of the indicator. The indicator is zincon or a salt thereof. The method is useful for estimating the ability of an oral care composition to deliver therapeutically-active zinc (II) ions to the oral cavity. Also provided is the use of zincon and a biorelevant substrate in vitro to determine the bioavailability of zinc (II) ions from an oral care composition comprising, a zinc source.

Abstract: Described herein are oral care compositions comprising an effective amount of an enzyme cocktail, wherein the enzyme cocktail comprises an alkaline protease and a second enzyme selected from cellulose, ?-glucanase, and combinations thereof, in an orally acceptable carrier, together with methods of making and using the same.

Abstract: A liquid cleansing composition comprising water in an amount sufficient to form a liquid composition, a fatty acid soap, a structuring agent, and talc. The cleansing composition has a creamy texture and provides good skinfeel properties.

Abstract: This invention relates to a dual phase mouthwash comprising a hydrophilic phase, a hydrophobic phase, and a hydrotrope, wherein the hydrophilic phase comprises an effective amount of a preservative selected from methylisothiazolinone, sodium benzoate, potassium sorbate, and combinations thereof, as well as to methods of using and of making such compositions.

Abstract: An apparatus for conducting oral care experiments with enamel block substrates (140) and a method of forming and using the same. In one aspect, the invention can be an apparatus for conducting oral care experiments comprising: a plate having a first major surface (111) and a second major surface (112); a handle (170) coupled to and extending from the plate; and at least one enamel block substrate mounted on the first major surface of the plate.

Abstract: Provided is a multi-chamber container for dispensing flowable substances, comprising: a body having: a first storage chamber for storing a first flowable substance, a second storage chamber for storing a second flowable substance, a first outlet zone, a second outlet zone, a first inlet that fluidly connects the first storage chamber with the first outlet zone, a second inlet that fluidly connects the second storage chamber with the second outlet zone, a first apparatus configured, on operation thereof to dispense from the first storage chamber via the first inlet into the first outlet zone a first predetermined volume of the first flowable substance, and a second apparatus configured, on operation thereof to dispense from the second storage chamber via the second inlet into the second outlet zone a second predetermined volume of the second flowable substance; and a closure having a first cavity, a second cavity, and a divider isolating the first cavity from the second cavity, wherein the closure is movable r

Abstract: Provided is a multi-chamber dispenser (1) of flowable substances, comprising: a rigid body (100) disposed around first (113) and second (123) storage chambers for storing respective first and second flowable substances, a first inlet fluidly connecting the first storage chamber (113) with a first outlet (141), a second inlet fluidly connecting the second storage chamber (123) with a second outlet (151), a first user-operable apparatus (140) at an exterior of the container and configured, on movement relative to the rigid body (100), to cause a volume of the first flowable substance to be dispensed from the first storage chamber (113) via the first inlet to the first outlet (141), and a second user-operable apparatus (150) at the exterior of the container and configured, on movement relative to the rigid body (100), to cause a volume of the second flowable substance to be dispensed from the second storage chamber (123) via the second inlet to the second outlet (151).

Abstract: A liquid cleansing composition comprising water in a sufficient amount to form a fluid composition; fatty acid soap; a divalent metal salt in an amount to provide a viscosity to entrain gas; and entrained gas to provide a specific gravity of not greater than 1.05 g/cm3. Optionally, a surfactant can also be included. The cleansing composition has a whipped texture. Also, a method of making the liquid cleansing composition.

Abstract: A method of producing an anhydrous antiperspirant composition comprising (a) providing a mixture of at least one antiperspirant active including a metal salt, and an anhydrous carrier for the at least one antiperspirant active in which the at least one antiperspirant active is dissolved, the carrier comprising a eutectic mixture of at least one basic compound selected from a basic amide and a basic amine and at least one member chosen from a cation and zwitterion; and (b) heating the mixture to form a stabilized eutectic system of the at least one antiperspirant active and the anhydrous carrier, and wherein the at least one antiperspirant active, the at least one basic compound and the at least one member chosen from a cation and zwitterion form a ternary eutectic system.

Abstract: A bottle for dispensing oral care fluid is provided. The bottle can include a body portion comprising a mouth, side surfaces, and a bottom surface arranged to hold a volume of oral care fluid; and a cap arranged to be secured to the mouth, wherein the cap comprises a integral cup sized to hold a portion of the volume of oral care fluid, wherein the integral cup includes an open end that mates with the mouth and a closed end including a flip-top member arranged at a distal end of the cap.