Patents Assigned to Consejo Superior de Investigaciones Cientificas (CSIC)
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Publication number: 20220178333Abstract: The invention relates to an internal combustion engine that comprises a first Brayton cycle comprising a mixed ionic-electronic conducting (MIEC) membrane that separates the O2 from the air such that the suctioned air current is free from N2; a second Brayton cycle combined in a binary manner with the first Brayton cycle and nested with a cycle selected from an Otto cycle and a diesel cycle performed by means of oxy-combustion. The second Brayton cycle transmits mechanical energy and thermal energy from exhaust gases to the first Brayton cycle. The first Brayton cycle provides to the second Brayton cycle compressed O2 from the MIEC membrane. By means of the present engine, the NOx emission into the atmosphere is prevented by the separation of N2 in the MIEC membrane.Type: ApplicationFiled: March 21, 2020Publication date: June 9, 2022Applicants: Universitat Politécnica de Valéncia, Consejo Superior de Investigaciones Científicas (CSIC)Inventors: Francisco José ARNAU MARTÍNEZ, Jesús Vicente BENAJES CALVO, David CATALÁN MARTÍNEZ, José María DESANTES FERNÁNDEZ, Luis Miguel GARCÍA-CUEVAS GONZÁLEZ, José Manuel SERRA ALFARO, José Ramón SERRANO CRUZ
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Patent number: 11332739Abstract: The present invention relates to a method for preparing cDNA infectious clones based on the genome of an attenuated Porcine Reproductive and Respiratory Syndrome virus (PRRSV) and uses thereof for preparing efficacious and safety-enhanced vaccines against PRRSV. The invention further comprises an infectious cDNA clone obtainable by such method. The invention further provides an attenuated modified PRRSV, and immunogenic compositions and vaccines comprising that attenuated PRRSV. The present invention further provides the attenuated PRRSV for use in the prophylaxis and/or the treatment of PRRSV infections, and the attenuated PRRSV for use as vaccine or medicament in the prophylaxis and/or the treatment of PRRSV infections.Type: GrantFiled: July 31, 2017Date of Patent: May 17, 2022Assignees: HIPRA SCIENTIFIC, S.L.U., CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Xavier Gibert Pérez, Marta Sitjà Arnau, Maria Mar Fenech Martínez, Santiago Francisco Elena Fito, Susana Martín García
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Patent number: 11324653Abstract: The invention relates to an exoskeleton for assisting human movement, which can be fitted to the user in terms of dimensions, tension and ranges of joint motion, either manually or automatically. The exoskeleton can be fitted to the user in the anteroposterior direction in the sagittal plane, with the user in a horizontal or sitting position, without requiring a functional transfer. The exoskeleton has a modular design which is compatible with human biomechanics and reproduces a natural and physiological movement in the user, with up to 7 actuated and controlled degrees of movement per limb, ensuring that the user maintains equilibrium during locomotion.Type: GrantFiled: November 25, 2015Date of Patent: May 10, 2022Assignees: MARSI BIONICS S.L., CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), UNIVERSIDAD POLITECNICA DE MADRIDInventors: Daniel Sanz Merodio, Manuel Javier Cestari Soto, Elena García Armada, Xavier Carrillo De Hijes
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Patent number: 11298416Abstract: The present application provides a modified Brucella strain, its use as a medicament, and its use as a medicament for the treatment and/or prevention of brucellosis. The Brucella strain has been modified through an inactivation of the wzm gene. Further, the present application provides a pharmaceutical composition which comprises the modified Brucella strain, its use as a medicament, and its use as a medicament for the treatment and/or prevention of brucellosis. The present application also provides a kit which comprises the modified Brucella strain and a pharmaceutically acceptable carrier or diluent and its use for the treatment and/or prevention of brucellosis.Type: GrantFiled: November 26, 2018Date of Patent: April 12, 2022Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), UNIVERSIDAD PÚBLICA DE NAVARRAInventors: María Jesús Grilló Dolset, Beatriz San Román Aberasturi, Leyre Palacios Chaves, Sara Mena Bueno, Ana Zabalza Baranguá
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Patent number: 11253833Abstract: A facility for industrial drying and/or encapsulation of thermolabile substances comprising at least one injection unit (1) wherein the thermolabile substance is introduced, an encapsulating material when the facility is used to encapsulate, a solvent, additives and an injection gas flow for obtaining droplets from the thermolabile substance. It further comprises a drying unit (2) through which the droplets and a drying gas are introduced for evaporating the solvent and comprises a collection unit (3) configured to separate the microcapsules generated from the drying gas and which is selected from a cartridge filter collector, a cyclone collector or a combination of the two. It also describes a method for the industrial encapsulation of thermolabile substances which is carried out at the proposed facility.Type: GrantFiled: December 20, 2017Date of Patent: February 22, 2022Assignees: BIOINICIA, S.L., CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: José María Lagaron Cabello, Sergio Castro Reina, José Manuel Valle, David Galan Nevado
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Patent number: 11253847Abstract: The invention relates to a method for producing catalysts by the method of combustion in solution, to the catalysts produced by said method, and to the particular use thereof in the reverse water-gas shift reaction and in the partial oxidation of the methane into synthesis gas. Therefore, it is understood that the present invention pertains to the area of the green industry aimed at the reduction of CO2 on the planet.Type: GrantFiled: December 28, 2017Date of Patent: February 22, 2022Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), CONSEJO NATIONAL DE INVESTIGACIONES CIENTICAS Y TECNICAS (CONICET)Inventors: María Consuelo Álvarez Galván, Martín Dapena Ospina, José Antonio Alonso Alonso, Loreto Troncoso Aguilera, Vanesa Cascos Jiménez, José Miguel Campos Martín, José Luis García Fierro, Horacio Falcón Richeni
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Publication number: 20220009091Abstract: Method for determining a grasping hand model suitable for grasping an object by obtaining a first RGB image including at least one object; obtaining an object model estimating a pose and shape of said object from the first image of the object; selecting a grasp taxonomy from a set of grasp taxonomies by means of a Convolutional Neural Network, with a cross entropy loss, thus, obtaining a set of parameters defining a coarse grasping hand model; refining the coarse grasping hand model, by minimizing loss functions referring to the parameters of the hand model for obtaining an operable grasping hand model while minimizing the distance between the finger of the hand model and the surface of the object and preventing interpenetration; and obtaining a mesh of the hand represented by the enhanced set of parameters.Type: ApplicationFiled: June 8, 2021Publication date: January 13, 2022Applicants: Naver France, Consejo Superior de Investigaciones Cientificas (CSIC), Universitatpolitècnica De Catalunya Plaça d'Eusebi Güell 6 Edifici Vertex, Planta 1Inventors: Francesc Moreno Noguer, Guillem Alenyà Ribas, Enric Corona Puyane, Albert Pumarola Peris, Grégory Rogez
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Patent number: 11168261Abstract: A method for recovering fibers embedded in a composite material including loading a furnace chamber with a volume of the composite material; thermolyzing the composite material in the furnace chamber, resulting in a gaseous fraction that is continuously evacuated from the furnace chamber, and a residue of fibers covered with char that is left in the furnace chamber; cracking the gaseous fraction from the thermolyzing operation, resulting in a mixture of condensable and non-condensable gases that can be recycled; injecting a stream of an oxygen-containing gas into the still hot furnace chamber after the thermolyzing is completed therein, to burn the char from the fibers in an exothermic combustion.Type: GrantFiled: June 1, 2018Date of Patent: November 9, 2021Assignees: BCIRCULAR COMPOSITES, SOCIEDAD LIMITADA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)Inventors: Roger Grau Garcia, Ferran Grau Garcia, Oriol Grau Garcia, Felix Antonio Lopez Gomez, Olga Rodriguez Largo
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Patent number: 11152535Abstract: This document describes a device that is monolithic and capable of emitting quantum light without using previous configurations known in the art that require certain elements which yield certain disadvantages, which may be solved by implementing the device of the invention described herein. In this way the use of a transmitter which controls the state of charge or the wavelength of quantum light emitters independently of current in the device is implemented and does function properly when quantum light emitters are embedded in photonic structures, like microcavities or photonic crystals (PC); this is achieved by stacking semiconductor layers with different composition and doping types. A quantum light emitter circuit, which is a quantum optical circuit comprising at least two of said devices, is also an as aspect of the invention disclosed herein.Type: GrantFiled: February 6, 2018Date of Patent: October 19, 2021Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Benito Alén Millán, David Fuster Signes, Yolanda González Díaz, Luisa González Sotos
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Publication number: 20210321053Abstract: An apparatus and a method using no switching elements for multiplexing and reading arrays of sensors whose electrical resistance is modulated by the signals to be measured are proposed. Sensor elements are arranged in groups and columns where each column is fed with a continuous voltage waveform of different amplitude, frequency and phase characteristics which then produce current signals that are modulated by the variable resistance signals to be measured. Modulated currents are summed row-wise and collected at the read-out circuits, either by applying a constant voltage to each row of the array or by connecting a capacitor and converting these current summations into output voltage signals. The read-out circuits de-multiplex each individual sensor signal to be measured by lock-in demodulation according to the frequencies and phases employed for the stimulation of each column.Type: ApplicationFiled: August 2, 2019Publication date: October 14, 2021Applicants: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), UNIVERSITAT AUTÒNOMA DE BARCELONA, FUNDACIÓ INSTITUT CATALÀ DE NANOCIÈNCIA I NANOTECNOLOGIA (ICN2), INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATSInventors: Anton GUIMERÀ BRUNET, Lluis Antoni TERÉS TERÉS, Michele DEI, Jose Agustín CISNEROS FERNÁNDEZ, Francisco SERRA GRAELLS, José Antonio GARRIDO ARIZA
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Patent number: 11131809Abstract: The invention relates to an integrated polarisation splitter based on a sub-wavelength multimode interference coupler (110), in other words, a multimode interference coupler (110) with an anisotropic multimode waveguide region formed by a plurality of sections of core material (210) and a plurality of sections of a cladding material (230) alternately arranged in a periodic way, with a period (?) smaller than the wavelength of a light propagated through said anisotropic region. The core material sections (210) are rotated an angle (?) greater than zero with respect to a perpendicular with an input waveguide (120) to increase the anisotropic character of the multimode waveguide region.Type: GrantFiled: January 24, 2019Date of Patent: September 28, 2021Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), UNIVERSIDAD DE MÁLAGAInventors: Aitor Villafranca Velasco, Alaine Herrero Bermello, Pedro Corredera, Robert Halir, Alejandro Ortega Moñux, J. Gonzalo Wangüemert Pérez, Inigo Molina Fernández
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Patent number: 11058650Abstract: The invention relates to the use of fatty acid amides with phenylalkylamines and of a pharmaceutical composition comprising at least one of these compounds in the prevention and/or treatment of fatty liver or a pathological condition or disease caused by fatty liver, either alcoholic or non-alcoholic, and, in particular, for the prevention and/or treatment of the alcoholic steatohepatitis or non-alcoholic steatohepatitis (NASH).Type: GrantFiled: November 24, 2015Date of Patent: July 13, 2021Assignees: FUNDACIÓN PÚBLICA ANDALUZA PARA LA INVESTIGACIÓN DE MÁLAGA EN BIOMEDICINA Y SALUD (FIMABIS), CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC), FUNDACIÓ INSTITUT MAR DTNVESTIGACIONS MÈDIOUESInventors: Fernando Rodríguez De Fonseca, Francisco Javier Pavón Morón, Juan Manuel Decara Del Olmo, Antonia Serrano Criado, Jesús Joglar Tamargo, Pedro Clapés Saborit, Rafael De La Torre Fornell, Magí Ferre Albaladejo, María Isabel Covas Planells, Montserrat Fito Colomer, Bruno Almeida Cotrim
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Patent number: 11029278Abstract: Ion sensor based on differential measurement comprising an ISFTET-REFET pair wherein the REFET is defined by a structure composed of an ISFET covered by a microreservoir where an internal reference solution is contained. The sensor comprises a first and a second ion-selective field effect transistor, an electrode, a substrate on the surface whereof are integrated the two transistors, connection tracks and the electrode and a structure adhered on the first ion-selective field effect transistor which creates a microreservoir on the gate of said first transistor, with the microreservoir having a microchannel which connects the microreservoir with the exterior and the microreservoir being filled with the reference solution.Type: GrantFiled: August 2, 2019Date of Patent: June 8, 2021Assignee: Consejo Superior de Investigaciones Cientificas (CSIC)Inventors: Antoni Baldi Coll, Carlos Dominguez Horna, Cecilia Jimenéz Jorquera, César Fernández Sánchez, Andreu Llobera Adan, Ángel Merlos Domingo, Alfredo Cadarso Busto, Isabel Burdallo Bautista, Ferrán Vera Gras
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Patent number: 11022705Abstract: The present invention relates to a system (10) and method for the volumetric and isotopic identification of the spatial distribution of ionizing radiation from point or extensive radioactive sources (3) in radioactive surroundings. More specifically, this system (10) comprises a gamma radiation detector (2) and an optical transducer (1) joined to each other and linked to a control unit to detect the absolute position of radioactive sources (3) relative to a visual reference located in the radioactive surroundings, and to determine the radioactive activity of the sources, that is to say it detects the isotope composition of the radioactive sources (3).Type: GrantFiled: February 1, 2018Date of Patent: June 1, 2021Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), UNIVERSITÄT DE VALENCIA, EMPRESA NACIONAL DE RESIDUOS RADIOACTIVOS, S.A. (ENRESA)Inventors: Jorge Agramunt Ros, Francisco Albiol Colomer, Alberto Corbi Bellot, Luis Caballero Ontanaya, César Domingo Pardo, Alberto Albiol Colomer
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Publication number: 20210139419Abstract: The present invention relates to a dynamic chemical network that mimics the transfer of information and ultimately produces a chemical response, for example a readable signal. More specifically, the invention discloses a dynamic system able to selectively sense a biologically-relevant analyte, such as cysteine, in its reduced or its oxidized form (cystine) in aqueous media and in a biofluid (such as urine) for diagnostic application. Due to this property, said dynamic system is useful for the detection of cysteine or its derivatives in biological fluids such as urine.Type: ApplicationFiled: April 4, 2019Publication date: May 13, 2021Applicant: Consejo Superior de Investigaciones Cientificas (CSIC)Inventors: Igancio ALFONSO RODRIGUEZ, Jordi SOLA OLLER, Maria LAFUENTE FABRA
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Patent number: 10876098Abstract: The invention relates to an unspecific peroxygenase of the Agrocybe aegerita fungus, obtained by means of directed molecular evolution to facilitate the functional expression thereof in an active, soluble and stable form. The peroxygenase described in the invention shows a significant improvement in the functional expression thereof, improved monooxygenase activity and reduced peroxidase activity, in relation to the monooxygenase and peroxidase activities showed by the unspecific wild-type peroxygenase of A. aegerita. The peroxygenase of the invention is useful in chemical processes, including industrial transformations such as the selective oxyfunctionalisation of carbon-hydrogen bonds of various organic compounds.Type: GrantFiled: November 14, 2016Date of Patent: December 29, 2020Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Patricia Molina Espeja, Francisco José Plou Gasca, Miguel Alcalde Galeote, Patricia Gómez De Santos
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Patent number: 10875780Abstract: The present invention relates to a new process for synthesising a crystalline material comprising structure Beta zeolite in nanocrystalline form, and which can comprise at least the following steps: (i) preparing a mixture comprising at least one source of water, at least one source of a tetravalent element Y, at least one source of a trivalent element X, at least one source of an alkali cation or alkaline earth metal cation (A), and at least one organic molecule selected from a monocyclic quaternary ammonium R1R2CycloN+, and a quaternary ammonium substituted with a cycloalkyl group R3R4R5R6N+. The molar composition of the mixture is: n X2O3:YO2:a A:m OSDA1:z H2O; ii) crystallising the mixture; and iii) recovering the crystalline material.Type: GrantFiled: June 5, 2018Date of Patent: December 29, 2020Assignees: UNIVERSITAT POLITECNICA DE VALENCIA, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Cecilia Gertrudis Paris Carrizo, Eva Maria Gallego Sanchez, Maria del Rocio Diaz Rey, Marta Evelia Martinez Armero, Maria Cristina Martinez Sanchez, Manuel Moliner Marin, Avelino Corma Canos
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Patent number: 10876049Abstract: The present invention relates to a method for producing mixtures of hydrocarbons and aromatic compounds for subsequent use as fuel components (preferably in the C5-C16 range) by catalytic conversion of the oxygenated compounds contained in aqueous fractions derived from primary biomass treatments, which can comprise at least the following steps: (i) bringing the aqueous mixture containing the oxygenated compounds derived from biomass in contact with a catalyst comprising at least W and/or Nb, and combinations of Nb and W with other elements, (ii) reacting the mixture with the catalyst in a catalytic reactor at temperatures between 50° C. and 450° C. and under pressures of 1 to 120 bar; and (iii) recovering the products obtained by a liquid/liquid separation process of the aqueous and organic phases.Type: GrantFiled: March 22, 2017Date of Patent: December 29, 2020Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC), UNIVERSITAT POLITECNICA DE VALENCIAInventors: Marcelo Eduardo Domine, Jose Manuel Lopez Nieto, Daniel Delgado Munoz, Alberto Fernandez-Arroyo Naranjo
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Patent number: 10858261Abstract: The present invention relates to a method for obtaining calcium aluminates for metallurgical use from non-saline aluminum slags by means of reactive grinding and thermal treatment.Type: GrantFiled: July 26, 2016Date of Patent: December 8, 2020Assignees: ARZYZ, S.A. DE C.V., CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Felix Antonio Lopez Gomez, Francisco Jose Alguacil Priego, Jose Ramon Gonzalez Gracia, Mario Sergio Ramirez Zablah
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Patent number: 10811220Abstract: An electron sensor and a system with a plurality of electron sensors for electron microscopy using an electron microscope. More specifically, the electron microscope generates an electron beam that includes at least one electron that impacts on a lateral reception surface of said electron sensor and this generates an electrical charge of electron-hole (e-h) pairs that are detected and/or measured by at least electrodes linked to an electric circuit unit to form a high dynamic range image and measure the energy of the electrons impacting each pixel of the image.Type: GrantFiled: July 6, 2017Date of Patent: October 20, 2020Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)Inventors: Ricardo Carmona Galán, Lionel Cervera Gontard