Abstract: A medicament delivery device comprises a housing and a syringe axially movable in the housing and the syringe having a barrel. The device further comprises a stopper axially movable in the barrel and which separates a first chamber and second chamber from one another. The stopper is axially movable in the barrel in response to a vapour pressure being received in the second chamber. The device also includes a biasing mechanism to axially move the syringe in the housing between a first syringe position and a second syringe position in response to a first reduction in the vapour pressure in the second chamber. In the first syringe position venting of the propellant from the second chamber through a first fluid pathway is permitted to enable the first reduction in the vapour pressure in the second chamber while venting of the propellant from the second chamber through a second fluid pathway is substantially prevented.

Abstract: A syringe assembly comprising a barrel for containing one or more medicaments, the barrel having a front outlet for allowing the expulsion of said one or more medicaments from the said barrel through said outlet, and a first stopper disposed in the barrel and axially moveable therein and defining a first volume in the barrel axially forwards of the first stopper and a second volume in the barrel axially rearwards of the first stopper. The first stopper has a two way valve that is moveable between a sealing configuration and an open configuration to selectively put the first volume in fluid communication with the second volume. The two way valve is moveable from the sealing configuration to the open configuration by an increase in fluid pressure in either of the first and second volumes.

Abstract: A sub-assembly of a medicament delivery device, the sub-assembly including a housing for containing a propellant source, and a locking ring for attachment to the housing. The housing is configured to receive a flange of a syringe, the locking ring is configured to retain a syringe flange received in the housing between the locking ring and the housing when the locking ring is attached to the housing.

Abstract: A medicament delivery device (10) comprising a syringe (12) having a barrel with an open end, and an axially moveable stopper (18) received in the barrel separating a first chamber axially forwards of the stopper from a second chamber axially rearwards of the stopper. The medicament delivery device further including an expandable drive housing (24) arranged to receive a propellant from a propellant source (36) for providing a vapour pressure, the expandable drive housing having a narrow channel in fluid communication with the second chamber. The expandable drive housing is expandable upon receiving propellant from the propellant source and, upon expansion, causes forward axial movement of the syringe.

Abstract: A medicament delivery device has a syringe, a housing, a needle shield, a biasing member and one or more blocking members. The needle shield is biased axially forwardly by the biasing member so as to selectively cover a needle of the syringe. However, the biasing member is prevented from biasing the needle shield axially forwardly until a radial movement of the blocking members has occurred, which is precipitated by a forward axial movement of the syringe. Consequently, the forward movement of the syringe releases the needle shield to automatically make safe the device.

Abstract: A medicament delivery device including a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further includes a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber.

Abstract: A valved container assembly has a container for containing a fluid, extending in an axial direction, and having an open front end and a valve disposed in the container. A plunger element is disposed axially rearward of the valve and is axially moveable in the container. The plunger element is configured to increase the pressure of a fluid in a first volume of the container upon axial movement of the plunger element relative to the valve. The valve includes a channel bypassing a seal, the channel having a first opening in fluid communication with the atmosphere outside of the valved container assembly and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable from a sealing configuration to an open configuration upon the pressure of the fluid in the first volume exceeding a first pressure threshold.

Abstract: An injection device having an outer housing configured to receive a syringe. The syringe has a barrel for containing medicament and a needle in fluid communication with the barrel. The device further has a needle shield axially moveable relative to the outer housing between a needle covering position and a needle exposing position and a helical compression spring to bias the needle shield axially forwardly toward the needle covering position. A locking sleeve, axially movable relative to the outer housing between a non-locking position and a locking position, selectively limits axial movement of the needle shield. In a first configuration, the needle shield is axially slideable within the locking sleeve to permit rearward axial movement of the needle shield from the needle covering position to the needle exposing position.

Abstract: A sub-assembly for a medicament delivery device including a housing, a propellant source contained in and axially moveable relative to said housing, and a button axially moveable relative to said housing. At least part of said button is disposed axially rearwardly of part of said propellant source. The button includes one or more radially flexible blocking members, and the button is moveable between a first axial position in which the one or more radially flexible blocking members are radially restrained by the housing in a radially inward position that limits rearward axial movement of the propellant source, and a second axial position in which the one or more radially flexible blocking members are able to flex to a radially outward position and permit rearward axial movement of the propellant source relative to the button and the housing.

Abstract: A syringe propellable by a propellant that boils at a predetermined temperature, the syringe comprising a barrel having an outlet at a front end, a stopper axially moveable in the barrel, and a third chamber for containing propellant. The stopper defines and separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe.

Abstract: Fluid delivery device for discharging a fluid, having: a housing; piston pump; biasing mechanism; and trigger mechanism. The housing has a basal end and a discharge end with outlet for discharging the fluid. The piston pump has a casing defining a pump chamber for storage of fluid, a piston slidably movable relative to the pump chamber, a piston plunger, and a delivery channel. The trigger mechanism is movable from a cocked configuration wherein the trigger mechanism prevents transfer of a biasing force of the biasing mechanism to the casing to a triggered configuration with the trigger mechanism enabling transfer of the biasing force to the casing to cause movement of the casing towards the housing outlet to discharge fluid from the pump chamber, along the delivery channel and out of the outlet of the housing. The biasing mechanism has one or more flexible catch members and a manually operable trigger.

Abstract: A sub-assembly of a medicament delivery device, the sub-assembly including a propellant source having a reservoir housing defining a reservoir and a stem having a bore therethrough, at least one inlet in fluid communication with the bore, and an open outlet end in fluid communication with the bore, the stein being moveable relative to the reservoir housing between a first position in which the at least one inlet is not in fluid communication with the reservoir and a second position in which the at least one inlet is in fluid communication with the reservoir, the propellant source further including a biasing member for biasing the stem towards the first position. The sub-assembly further including a collet member having a first plurality of radially flexible fingers and a second plurality of radially flexible fingers.

Abstract: A valved container assembly (10) comprising a container (12) for containing a fluid, the container (12) extending in an axial direction and having at least one venting opening (12a) at a front end and at least one dispensing opening (12b). The valved container assembly (10) further comprising a valve (14) disposed in the container (12) and a plunger element (20) disposed axially rearward of the valve (14), the plunger element (20) being axially moveable in the container (12) and defining a first volume (22) in the container (12) between the plunger element (20) and the valve (14), where the plunger element (20) is configured to increase the pressure of a fluid in the first volume (22) upon axial movement relative to the valve (14).

Abstract: A syringe assembly having a barrel for containing one or more medicaments and a stopper disposed in the barrel defining and separating a first volume and a second volume within the syringe assembly. The stopper includes a permanent seal fluidly sealing the stopper to the barrel about the entire perimeter of the stopper intermediate the first volume and second volume, and a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the second volume and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable between a sealing configuration and an open configuration to selectively seal the channel from the first volume and is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume or second volume exceeding a first pressure threshold.

Abstract: The present invention provides dose counter for displaying a count indication of the number or quantity of doses dispensed from or remaining in a container associated, in use, with the dose counter, comprising an indicator member comprising dose indicia and a priming indicator for prompting a user to carry out one or more priming actuations of the container. The priming indicator is initially arranged to at least partially overly the indicator member to thereby at least partially obscure viewing of the dose indicia of the indicator member until the one or more priming actuations of the container have been completed. The priming indicator is movable after the one or more priming actuations have been completed into a disposition where it no longer obscures viewing of the dose indicia of the indicator member. The invention also provides a dispensing apparatus comprising the dose counter.

Abstract: A valved container assembly which has a container for containing a fluid, the container extending in an axial direction and having an open front end and a valve disposed in the container. The valved container assembly is configured so that forward axial movement of the valve relative to the container is inhibited. A plunger element is disposed axially rearward of the valve and is axially moveable in the container. The plunger element is configured to increase the pressure of a fluid in a first volume of the container upon forward axial movement relative to the valve. The valve includes a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the atmosphere outside of the valved container assembly and a second opening selectively sealed from the first volume by a resilient seal.

Abstract: The present invention provides dose counter for displaying a count indication of the number or quantity of doses dispensed from or remaining in a container associated, in use, with the dose counter, comprising an indicator member comprising dose indicia and a priming indicator for prompting a user to carry out one or more priming actuations of the container. The priming indicator is initially arranged to at least partially overly the indicator member to thereby at least partially obscure viewing of the dose indicia of the indicator member until the one or more priming actuations of the container have been completed. The priming indicator is movable after the one or more priming actuations have been completed into a disposition where it no longer obscures viewing of the dose indicia of the indicator member. The invention also provides a dispensing apparatus comprising the dose counter.