Patents Assigned to Cook Biotech Incorporated
-
Publication number: 20210308342Abstract: The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.Type: ApplicationFiled: June 22, 2021Publication date: October 7, 2021Applicants: Cook Medical Technologies LLC, Cook Biotech IncorporatedInventors: Rhonda Peck, Bhavin B. Shah, Umesh H. Patel, Krista Gearhart, Steven Charlebois, Keith Milner, Eric J. Rodenberg
-
Patent number: 11064987Abstract: Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.Type: GrantFiled: May 16, 2017Date of Patent: July 20, 2021Assignee: Cook Biotech IncorporatedInventors: F. Joseph Obermiller, Michael C. Hiles, Matthew R. Graham, Clay D. Fette
-
Patent number: 11065368Abstract: The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours.Type: GrantFiled: March 14, 2014Date of Patent: July 20, 2021Assignees: Cook Biotech Incorporated, Cook Medical Technologies LLCInventors: Rhonda Peck, Bhavin Shah, Umesh H. Patel, Krista Gearhart, Steven Charlebois, Keith Milner, Eric J. Rodenberg
-
Patent number: 11026667Abstract: Some aspects of the present invention are directed to unique products and methods for treating fistulae and other passageways and openings in the body. In some preferred forms, an inventive construct will include an elongate graft body that incorporates a plurality of sheet or sheet-like segments. The plurality of sheet or sheet-like segments, in some arrangements, will be stacked in a generally longitudinal direction along the length of the plug body, and optionally, the segments will be received over one or more elongate elements. Elongate elements of this sort can take a variety of forms including a suture, wire, filament, or other relatively thin-bodied elongate member, although in some forms, an elongate element will be or include a somewhat heftier structure such as a biodegradable or non-biodegradable three-dimensional body.Type: GrantFiled: September 14, 2016Date of Patent: June 8, 2021Assignee: Cook Biotech IncorporatedInventors: Charles W. Agnew, Mark Duncan, Chad E. Johnson
-
Patent number: 10973856Abstract: Described our medical compositions and methods including a particulate extracellular matrix tissue in admixture with sugar. Such medical compositions, in dried forms, can demonstrate enhanced rehydration properties. Medical compositions and products as described herein find particular use in treating diseased and/or damaged tissue, such as wound repair. Related methods of manufacture and use are also described.Type: GrantFiled: March 14, 2014Date of Patent: April 13, 2021Assignee: Cook Biotech IncorporatedInventors: Michelle Chutka, Michael C. Hiles
-
Publication number: 20210015656Abstract: Tissue adjustment implants useful for adjusting a position of tissue in a patient are described. In an embodiment, a tissue adjustment implant includes a main body having a series of outwardly-extending projections. The tissue adjustment implants can be used in a variety of treatments, such as in the treatment of Obstructive Sleep Apnea and snoring.Type: ApplicationFiled: October 5, 2020Publication date: January 21, 2021Applicants: Cook Medical Technologies LLC, Cook Biotech IncorporatedInventors: Christine Bronikowski, Ryan Bernstein, Joseph Obermiller, Patrick C. Melder, P. Arun Mohan
-
Publication number: 20200405976Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula. The needle cannula or other device can be received in a capsule and/or other container. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.Type: ApplicationFiled: May 13, 2020Publication date: December 31, 2020Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Michael L. Taylor, Cara McCammon, Rae Ritchie
-
Publication number: 20200375177Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula and being therein impregnated with a cryopreservation medium. The needle cannula or other device can be received in a capsule and/or other container, which in some forms can contain additional amounts of the cryopreservation medium occurring external of the lumen. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.Type: ApplicationFiled: March 3, 2020Publication date: December 3, 2020Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Michael L. Taylor, Claus Soendergaard, Cara McCammon, Rae Ritchie
-
Patent number: 10799388Abstract: Tissue adjustment implants useful for adjusting a position of tissue in a patient are described. In an embodiment, a tissue adjustment implant includes a main body having a series of outwardly-extending projections. The tissue adjustment implants can be used in a variety of treatments, such as in the treatment of Obstructive Sleep Apnea and snoring.Type: GrantFiled: January 15, 2018Date of Patent: October 13, 2020Assignees: Cook Medical Technologies LLC, Cook Biotech IncorporatedInventors: Christine Bronikowski, Ryan Bernstein, Joseph Obermiller, Patrick C. Melder, P. Arun Mohan
-
Publication number: 20200316257Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft comprising remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: ApplicationFiled: June 19, 2020Publication date: October 8, 2020Applicant: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller
-
Publication number: 20200276399Abstract: Disclosed are powder spray dispensing devices for comminuted extracellular matrix powder materials, and terminally sterilized products for providing such devices, as well as related methods for manufacture and use. A powder spray dispensing device can include a squeeze pump bottle having a bottle body defining a bottle opening and an interior chamber. A dry collagenous extracellular matrix material powder is received in the interior chamber of the squeeze pump bottle, and a cap is fitted over the bottle opening. The cap has a dispensing spout fluidly communicating with the bottle opening and having a spout lumen, desirably of decreasing diameter in a direction extending away from the bottle opening.Type: ApplicationFiled: February 28, 2020Publication date: September 3, 2020Applicant: Cook Biotech IncorporatedInventor: Christopher Fecteau
-
Patent number: 10688219Abstract: Described are embodiments of a multilaminate or multiple layer implantable surgical graft comprising remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.Type: GrantFiled: June 10, 2009Date of Patent: June 23, 2020Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, Jeffrey Miller
-
Publication number: 20200188559Abstract: Described are packaged, sterile medical graft products containing controlled levels of a growth factor such as Fibroblast Growth Factor-2 (FGF-2). Also described are methods of manufacturing medical graft products wherein processing, including sterilization, is controlled and monitored to provide medical graft products having modulated, known levels of a extracellular matrix factor, such as a growth factor, e.g. FGF-2. Preferred graft materials are extracellular matrix materials isolated from human or animal donors, particularly submucosa-containing extracellular matrix materials. Further described are ECM compositions that are or are useful for preparing gels, and related methods for preparation and use.Type: ApplicationFiled: February 26, 2020Publication date: June 18, 2020Applicant: Cook Biotech IncorporatedInventors: Michael C. Hiles, Jason P. Hodde, David M.J. Ernst, Lal Ninan
-
Patent number: 10575516Abstract: Disclosed are products having animal tissue packed within the lumen of a device such as a needle cannula and being therein impregnated with a cryopreservation medium. The needle cannula or other device can be received in a capsule and/or other container, which in some forms can contain additional amounts of the cryopreservation medium occurring external of the lumen. Methods of use of the products are also described and can include ejecting the animal tissue from the lumen of device using pressurized liquid passed through the lumen, potentially to deliver the animal tissue directly into a patient. Methods of manufacture of the products are also described.Type: GrantFiled: November 14, 2018Date of Patent: March 3, 2020Assignee: Cook Biotech IncorporatedInventors: Umesh H. Patel, Michael L. Taylor, Claus Sondergaard, Cara McCammon, Rae Ritchie
-
Patent number: 10512463Abstract: Described are medical devices useful for applying a bolster material to a surgical fastening device such as a stapler, and related methods of manufacture and use. The devices include an applicator element for receipt between arms of the stapler, and a bolster material, desirably a remodelable extracellular matrix material, coupled to the applicator element. In certain embodiments, the bolster material is held by the applicator element, for example having at least a portion looped around or received through or over a portion of the applicator element. Also described are unique implantable materials including coatings of dried, reversible adhesive.Type: GrantFiled: October 2, 2015Date of Patent: December 24, 2019Assignee: Cook Biotech IncorporatedInventors: Michael C. Hiles, Umesh H. Patel, Bhavin Shah, Chad S. McAlexander
-
Patent number: 10500309Abstract: Described are medical products including an adhesive containing a polypeptide component such as gelatin and a tackiness-providing polyhydroxy compound, such as at least one compound selected from the group consisting of glycerin and fructose. Such medical products can find use as a bolster material for use in conjunction with a surgical fastening device such as a stapler. Other medical applications utilizing a medical product of the invention include tissue repair and pharmaceutical delivery to a desired location. Related methods of manufacture and use are also described.Type: GrantFiled: September 24, 2008Date of Patent: December 10, 2019Assignee: Cook Biotech IncorporatedInventors: Bhavin Shah, Paul J. Hall
-
Publication number: 20190351241Abstract: Described are implantable pouch products having a segmental lamination structure that provides an interior pocket for receiving a medical device, for example an electronic medical device such as a cardiac pacemaker or defibrillator. Also described are methods for making and using such products.Type: ApplicationFiled: January 18, 2019Publication date: November 21, 2019Applicant: Cook Biotech IncorporatedInventor: Tyler Novak
-
Patent number: 10470749Abstract: Described are medical graft products, systems, and methods useful for treating fistulae, particularly enterocutaneous fistulae. Certain products of the invention are configured to have portions residing in and around a primary fistula opening in a wall of the alimentary canal. One such product includes a biocompatible graft body which is configured to block at least the primary opening. The graft body includes a capping member connected to an elongate plug member. The capping member is configured to contact portions of the alimentary canal wall adjacent to the primary opening, and the elongate plug member is configured to extend into at least a portion of the fistula. A graft product of this sort may be particularly adapted to allow a portion of the capping member to be positioned alongside an exterior, lateral surface of the plug member, e.g., when placed in a delivery device lumen. Such a capping member may be hingedly or non-hingedly coupled to the elongate plug member.Type: GrantFiled: September 23, 2016Date of Patent: November 12, 2019Assignee: Cook Biotech IncorporatedInventors: F. Joseph Obermiller, Steve Chen
-
Patent number: 10471182Abstract: Described are packaged, sterile medical graft products containing controlled levels of a growth factor such as Fibroblast Growth Factor-2 (FGF-2). Also described are methods of manufacturing medical graft products wherein processing, including sterilization, is controlled and monitored to provide medical graft products having modulated, known levels of a extracellular matrix factor, such as a growth factor, e.g. FGF-2. Preferred graft materials are extracellular matrix materials isolated from human or animal donors, particularly submucosa-containing extracellular matrix materials. Further described are ECM compositions that are or are useful for preparing gels, and related methods for preparation and use.Type: GrantFiled: October 25, 2016Date of Patent: November 12, 2019Assignee: Cook Biotech IncorporatedInventors: Michael C. Hiles, Jason P. Hodde, David M.J. Ernst, Lal Ninan
-
Publication number: 20190336650Abstract: Described are packaged, sterile medical graft products containing controlled levels of a growth factor such as Fibroblast Growth Factor-2 (FGF-2). Also described are methods of manufacturing medical graft products wherein processing, including sterilization, is controlled and monitored to provide medical graft products having modulated, known levels of a extracellular matrix factor, such as a growth factor, e.g. FGF-2. Preferred graft materials are extracellular matrix materials isolated from human or animal donors, particularly submucosa-containing extracellular matrix materials. Further described are ECM compositions that are or are useful for preparing gels, and related methods for preparation and use.Type: ApplicationFiled: June 26, 2019Publication date: November 7, 2019Applicant: Cook Biotech IncorporatedInventors: Michael C. Hiles, Jason P. Hodde, David M.J. Ernst, Lal Ninan