Abstract: Silicone hydrogel contact lenses are provided which have reduced modulus and contact angle properties, and which have acceptable wettabilities for use in daily wear and extended or continuous wear applications.

Abstract: Multifocal contact lenses and methods and uses are described. The multifocal contact lenses include an optic zone. The optic zone has an aspheric power profile that provides a near vision refractive power and a distance vision refractive power, and provides an Add power that corresponds to the difference between the near vision refractive power and the distance vision refractive power. The multifocal contact lenses can improve binocular vision of presbyopic subjects by being prescribed such that the non-dominant eye contact lens is over-corrected for distance vision, and both multifocal contact lenses are under-corrected for the Add power requirement of the subject. Batches and sets of multifocal contact lenses are also described.

Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products having relatively large amounts of removable or extractable materials. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.

Abstract: Silicone hydrogel contact lenses comprising an ionic component sustain release of beneficial cationic polymers.

Abstract: Contact lenses comprising phosphorylcholine groups release beneficial polyionic or guanidinium-containing agents.

Abstract: Antimicrobial ophthalmic devices such as contact lenses, ocular inserts, ocular bandages, and intraocular lenses comprise a hydrogel and an antimicrobially-effective amount of epsilon polylysine non-covalently attached to the hydrogel.

Abstract: Contact lenses comprising an ionic component are packaged with a beneficial cationic agent in a temperature-sensitive packaging solution and/or a low ionic strength packaging solution.

Abstract: Method and apparatus for manufacturing a contact lens comprising: dispensing a plurality of separate portions (24) of a liquid composition onto a contact lens mold section (12, 16), each separate portion of the liquid composition having a volume of less than about 1000 nano-liters.

Abstract: Hydrogel contact lenses that are derived from a polymerizable composition including at least one hydrophilic monomer and at least one phosphine-containing component are described. The hydrogel of the contact lenses can be a silicone hydrogel or a non-silicone hydrogel. Use of polymerizable compositions comprising a phosphine-containing component can be cured under both inert and air atmospheres, and can be used to form hydrogel contact lenses having improved shape retention properties, having improved resistance to discoloration. Batches of hydrogel contact lenses and methods of making hydrogel contact lenses are also described.

Abstract: Methods of making or providing ophthalmic lenses include using accommodative error measurements in the design or selection of one or more ophthalmic lenses. In some examples, the ophthalmic lenses are contact lenses.

Abstract: A color reference guide is provided for ensuring consistency among color-printed products. The guide can include a plurality of calibration pages and each calibration page can include a calibration bar and a color logo. The calibration bar can be the same on each calibration page and the color logo can be different on each calibration page. A method of providing consistency among color-printed products is also provided and involves comparing a printed logo to a corresponding color logo in the color reference guide. The color reference guide can be used in a variety of printing processes, for example, in a CMYK four-color printing process or in a G7 color printing process. The color reference guide and method are also useful in calibrating a color printer.

Abstract: Silicone hydrogel contact lenses, when hydrated, have a plurality of depressions on one or more of the lens surfaces. The depressions have a depth less than 1 micrometer, or less than 100 nanometers. The silicone hydrogel contact lenses have not been subject to treatment with plasma. Methods of manufacturing the silicone hydrogel contact lenses are also disclosed.

Abstract: Methods, devices, and systems for manufacturing ophthalmic lenses are described in which lens bodies are placed in cavities of lens carriers that are fluidly connected to reservoirs, flow ducts and sub-cavity base channels that provide enhanced washing and wet processing of the lenses.

Abstract: Optically clear silicone hydrogel contact lenses are described that comprise a polymeric lens body that is the reaction product of a polymerizable composition comprising at least 25 wt. % of at least one hydroxyalkyl methacrylate; and at least 20 wt. % of at least one HEMA-compatible bifunctional polysiloxane comprising at least 6 siloxane groups and having an HLB value of at least 5 and/or a hydroxyl group content of at least 1 wt. %.

Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable levels of energy loss are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer which is a dual-end methacrylate end-capped polydimethylsiloxane having a number average molecular weight of at least 7,000 daltons. The average energy loss of the silicone hydrogel contact lenses is from about 30% to about 45% when the lenses are fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.

Abstract: Ophthalmically acceptably wettable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group, the first siloxane monomer having a number average molecular weight of from 400 daltons to 700 daltons; and a second siloxane monomer having a number average molecular weight greater than 7,000 daltons; wherein a total amount of siloxane monomers present in the polymerizable composition is from 30 unit parts to 50 unit parts; the lenses also include units derived from at least one hydrophilic amide monomer having one N-vinyl group that is present in the polymerizable composition in an amount from 30 to 60 unit parts.

Abstract: A lens body comprising at least one form of boronic acid, boronic ester or boronic anhydride is provided. The lens body is contacted with a solution comprising at least one form of TRIS. A contact lens package including the contact lens, and methods of producing and using the contact lens, are also provided.

Abstract: Hydrogel contact lenses that are derived from a polymerizable composition including at least one hydrophilic monomer and at least one phosphine-containing component are described. The hydrogel of the contact lenses can be a silicone hydrogel or a non-silicone hydrogel. Use of polymerizable compositions comprising a phosphine-containing component can be cured under both inert and air atmospheres, and can be used to form hydrogel contact lenses having improved shape retention properties, having improved resistance to discoloration. Batches of hydrogel contact lenses and methods of making hydrogel contact lenses are also described.

Abstract: A hydrogel soft contact lens which is superior in extended-wearability, lens movement, wear comfort, and which does not adhere to a cornea when worn is provided. The lens provided can be a silicone hydrogel contact lens which contains units of hydrophilic siloxane monomers and amide-group-containing monomers having an N-vinyl group.

Abstract: Silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including 30-60 unit parts by weight of a hydrophilic monomer(s) having one N-vinyl group, 10 to 50 unit parts by weight of 2-hydroxyethyl methacrylate (HEMA), and a first siloxane monomer component comprising a siloxane monomer of formula (1) as described herein or a siloxane monomer of formula (2) as described herein or a siloxane monomer of formula (3) as described herein or any combination thereof, where the total amount of siloxane monomer(s) present in the polymerizable composition is from 15 to 40 unit parts by weight. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.