Abstract: Ophthalmic lens molds made from at least one vinyl alcohol copolymers with high amorphous content, ophthalmic lenses including silicone hydrogel contact lenses formed using these molds, packaged ophthalmic lenses present in a solution comprising the at least one vinyl alcohol copolymer with high amorphous content, and related methods are described. The methods of manufacturing ophthalmic lenses can use wet demolding, delensing or demolding and delensing processes involving dissolving the molds in water or an aqueous solution.

Abstract: An ophthalmic composition for administration to an eye of a patient for the treatment of an ocular infection. The ophthalmic composition contains an ?-polylysine (?PL) in an amount effective to treat or control or prevent the ocular infection.

Abstract: Ophthalmic lens molds made from at least one vinyl alcohol copolymers with high amorphous content, ophthalmic lenses including silicone hydrogel contact lenses formed using these molds, packaged ophthalmic lenses present in a solution comprising the at least one vinyl alcohol copolymer with high amorphous content, and related methods are described. The methods of manufacturing ophthalmic lenses can use wet demolding, delensing or demolding and delensing processes involving dissolving the molds in water or an aqueous solution.

Abstract: Ophthalmic device molds made from at least one highly amorphous vinyl alcohol polymer, ophthalmic devices such as ocular inserts and contact lenses and including silicone hydrogel devices formed using these molds, and related methods are described. The methods of manufacturing ophthalmic devices can use dry or wet demolding processes, or dry or wet delensing processes.

Abstract: A method is provided for manufacturing ophthalmically-acceptable, distortion-free silicone hydrogel contact lenses without the use of volatile organic solvents in the manufacturing process. The contact lenses are extract with an extraction liquid comprising an aqueous solution of a non-volatile organic solvent, such as ethyl lactate.

Abstract: Ophthalmic device molds made from at least one vinyl alcohol copolymer and having a static sessile drop contact angle of less than 70 degrees, ophthalmic devices such as ocular inserts and contact lenses and including silicone hydrogel devices formed using these molds, and related methods are described. The methods of manufacturing ophthalmic devices can use dry or wet demolding processes, or dry or wet delensing processes.

Abstract: A contact lens package includes a sealed contact lens package and a wrap coupled to the sealed contact lens package. The wrap has one or more panels. One of more of the panels includes a printed surface that includes a unique device identifier, which is provided in both human readable form that includes numbers or letters, or both, and machine readable form, such as a bar code. A method of manufacturing a contact lens package includes providing the sealed contact lens package and coupling the wrap to the sealed contact lens package.

Abstract: HEMA-compatible siloxane monomers are described that can be used to manufacture contact lenses that combine the attributes of HEMA-based contact lenses with the high oxygen permeability of silicone hydrogel lenses. Optically clear silicone hydrogel contact lens can be manufactured that comprise a polymeric lens body that is the reaction product of a polymerizable composition comprising: a) at least 25 wt. % of at least one hydroxyalkyl methacrylate; and b) at least 20 wt. % of at least one HEMA-compatible polysiloxane.

Abstract: HEMA-compatible siloxane monomers are described that can be used to manufacture contact lenses that combine the attributes of HEMA-based contact lenses with the high oxygen permeability of silicone hydrogel lenses. Optically clear silicone hydrogel contact lens can be manufactured that comprise a polymeric lens body that is the reaction product of a polymerizable composition comprising: a) at least 25 wt. % of at least one hydroxyalkyl methacrylate; and b) at least 20 wt. % of at least one HEMA-compatible polysiloxane.

Abstract: The invention relates to a method of making a contact lens, the method comprising identifying the eccentricity of a lens produced in a mould half, lathing the lens and adjusting the path of the lathe to take account of the eccentricity, and a computer programme for controlling the lathe.

Abstract: A mould for the production of a contact lens, the mould comprising a first mould half shaped to provide the front surface of the contact lens; and a second mould half shaped to provide the rear surface of the contact lens, wherein the first and second mould halves form a mould cavity, wherein the first mould half has a first rim and the second mould half has a second rim, and the first and second rims fit together to provide a seal for the mould cavity, wherein the first rim is inclined at an angle of x relative to an axis passing through the centre of the first and second mould halves, wherein x is from 30 to 60°, and wherein the second rim is inclined at an angle of x-y relative to the axis passing through the centre of the first and second mould halves, where y is from 0 to 4°, and wherein the first and second rims provide a guide for the mould halves, a method of making a contact lens using the mould and a method of making a mould.

Abstract: Ophthalmic device molds made from at least one water-soluble vinyl alcohol copolymer, ophthalmic devices such as ocular inserts and contact lenses and including silicone hydrogel devices formed using these molds, packaged ophthalmic devices present in a solution comprising the at least one water-soluble vinyl alcohol copolymer, and related methods are described. The methods of manufacturing ophthalmic devices can use wet demolding processes, or wet delensing processes or both wet demolding and wet delensing processes involving dissolving the molds in water or an aqueous solution.

Abstract: Silicone hydrogel contact lenses comprising an ionic component sustain release of beneficial cationic polymers.

Abstract: Ophthalmic lens molds made from one or more thermoplastic polymer having a low level of UV light transmittance (UV % T) ophthalmic lenses including silicone hydrogel contact lenses molded using these thermoplastic polymer having low UV % T, and methods of manufacturing ophthalmic lenses by cast molding a polymerizable composition in mold members formed of these thermoplastic polymers having low UV % T and curing the polymerizable composition using UV light are described.

Abstract: Ophthalmic device molds made from at least one water-soluble vinyl alcohol copolymer, ophthalmic devices such as ocular inserts and contact lenses and including silicone hydrogel devices formed using these molds, packaged ophthalmic devices present in a solution comprising the at least one water-soluble vinyl alcohol copolymer, and related methods are described. The methods of manufacturing ophthalmic devices can use wet demolding processes, or wet delensing processes or both wet demolding and wet delensing processes involving dissolving the molds in water or an aqueous solution.

Abstract: Technology to determine the angle of repose of a lens, such as the angle of repose of a contact lens on an eye, includes storing an image including the lens captured using a camera and executing graphical user interface logic. The graphical user interface logic includes a frame or frames including the captured image, and graphical constructs prompting input identifying a set of locations on the captured image that are usable to define a location of the lens in the image, and a location usable to define an angle of repose of the lens in the image. The input data accepted via the graphical user interface is processed to determine angle of repose of the lens. The angle of repose of the lens is used to produce a specification for a lens.

Abstract: Methods of manufacturing a contact lens are provided. Such methods include using an adjustable mandrel to fixedly retain a single mold section carrying a polymerized contact lens product and delensing the contact lens product from the single mold section. Adjustable mandrels are also provided.

Abstract: Optically clear silicone hydrogel contact lenses are described that comprise a polymeric lens body that is the reaction product of a polymerizable composition comprising at least 25 wt. % of at least one hydroxyalkyl methacrylate; and at least 20 wt. % of at least one HEMA-compatible bifunctional polysiloxane comprising at least 6 siloxane groups and having an HLB value of at least 5 and/or a hydroxyl group content of at least 1 wt. %.

Abstract: Miscible polymerizable compositions comprising at least one primary amine-containing methacrylate monomer, or at least one primary amine-containing methacrylamide monomer, in addition to 20-80 wt. % siloxane monomer, 20-80 wt. % hydrophilic monomer, cross-linking agent, and polymerization initiator, are described. These polymerizable compositions can be used to form silicone hydrogel contact lenses, and in methods of manufacturing silicone hydrogel contact lenses.

Abstract: Methods, devices, and systems for moving wet ophthalmic lenses are described in which the ophthalmic lenses are first placed in wells of lens carriers and are centered by the structure of the wells. The carriers are then moved to a transfer module of a packaging system for transferring the ophthalmic lenses in blister packages. The transfer from the carriers to the blister packages are performed by a pick and place robot having pickup heads sized and configured for suctioning the ophthalmic lenses from the lens carriers.