Abstract: The present disclosure provides a method for recycling polystyrene. The method includes providing a photothermal colorant and a polystyrene, with the photothermal colorant being operably coupled to the polystyrene. The method further includes causing the photothermal colorant to generate heat by irradiating the photothermal colorant with light. A styrene monomer is formed by allowing the heat to degrade the polystyrene. The disclosure also provides a system for polystyrene recycling, including a first vessel configured to receive the photothermal colorant and polystyrene, a light source configured to irradiate the photothermal colorant within the first vessel, a vacuum source configured to be operably coupled to the first vessel, and a second vessel configured to receive the styrene monomer from the first vessel.

Abstract: The disclosure includes example processes for creating stretchable electronics from multi-layer flex printed circuit boards (flex-PCBs), and example platforms for soft robotic sensor arrays (SRSAs) for electric mapping applications, such as cardiac voltage mapping.

Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following Formulas (I), or a pharmaceutically acceptable salt thereof (IA), or a pharmaceutically acceptable salt thereof (II), or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.

Abstract: A method for rendering biological tissue sufficiently optically transparent for three-dimensional light microscopy imaging, comprising incubating biological tissue with an optical clearing solution, wherein the optical clearing solution comprises: (i) 20-50 wt % formamide, (ii) 10-90 wt % glycerol, and (iii) water as remainder. Also described herein is a method for ridding tissue of blood to make them amenable for optical clearing, comprising incubating biological tissue in a decolorizing solution, wherein the decolorizing solution comprises: (i) 0.5-3 wt % hydrogen peroxide, (ii) 0.05-1 wt % sodium azide, (iii) 5-20 wt % DMSO, and (iv) phosphate buffered saline as a remained.

Abstract: An endotracheal tube placement system for securing an endotracheal tube relative to a patient's vocal chords during surgery is disclosed. The system can include a clamp that receives the endotracheal tube and a clamp lock that selectively retains the clamp in a clamped position holding the endotracheal tube in place relative to the clamp. The clamp and clamp lock can be fixed to the mouth area of the patient's face using tape strips. The system may also include positioners sized to be placed between the upper and lower teeth of the patient when the clamp is fixed to a patient's face.

Abstract: The present disclosure is directed to genetically modified bacteria that produce a diffusible signal factor (DSF). The disclosure also provides methods for treating or preventing Salmonella infection/invasion in a subject. The disclosure further provides vectors and compositions for carrying out the methods disclosed herein.

Abstract: The present disclosure is directed to methods and compositions for increasing resistance to blossom end rot in fruit, increasing fruit size, and increasing antioxidant content in fruits. Embodiments of the disclosure also include plant cells, plants, and fruits including a modified ADP-glucose pyrophosphorylase (AGPase). Also included are nucleic acid constructs, and methods of breeding for enhanced blossom end rot resistance.

Abstract: Presented herein are directed to systems and methods for detecting conditions in subjects provided with stimuli. A computing system may send, to a headset situated on a head of a first subject in an upright posture, an instruction for the headset to present a stimuli to direct the subject to perform a task. The computing system may receive, via a tomography scanner arranged about the head of the first subject, a dataset defining a first plurality of tomograms of a first nervous system of the first subject. The computing system may obtain, via a sensor, a first signal associated with a first physiological function of the first subject over the time period. The computing system may determine, from the plurality of conditions, a condition associated with the first nervous system of the first subject based on applying a model to the first plurality of tomograms and the first signal.

Abstract: Presented herein are devices for detected photons for tomography. The device can include a plurality of scintillator arrays. Each of the plurality of scintillator arrays can be configured to emit photons in response to receipt of ionizing radiation. Each respective scintillator array of the plurality of scintillator arrays can include a first region corresponding to a first end to an intermedial section of the respective scintillator array. The intermedial section can have a first cross-sectional dimension. Each respective scintillator array of the plurality of scintillator arrays can include a second region corresponding to the intermedial section to a second end of the respective scintillator array. The device can include a light guide coupled with the first end of each of the plurality of scintillator arrays. The device can include a photodetector coupled with the second end of the second scintillator array.

Abstract: Systems, methods, and devices having improved conformal properties for biomedical signal measurement are disclosed. A device can have a first polymer substrate coupled to a conductive layer forming a conductive trace electrically coupled to a conductive pad exposed via an opening. The device can have a second polymer substrate forming a first cavity between the first polymer substrate and the second polymer substrate. The device can have a first inlet portion that receives a fluid that expands the first cavity causing the device to conform to an anatomical structure. The structure can be an atrium, such as the left atrium, of the heart of a patient. The device can conform to the walls of the tissue structure, and the conductive pad exposed via the opening can detect a signal from the wall of the tissue structure. The signal can be provided to an external measurement device for processing.

Abstract: The present technology provides compounds as well as compositions including such compounds useful in targeted radiotherapy of cancer and/or mammalian tissue overexpressing prostate specific membrane antigen (“PSMA”) where the compounds are represented by the following: or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, wherein M1 is independently at each occurrence an alpha-emitting radionuclide. Equivalents of such compounds are also disclosed.

Abstract: The present technology provides compounds, as well as compositions including such compounds, useful for imaging and/or treatment of a glioma, a breast cancer, an adrenal cortical cancer, a cervical carcinoma, a vulvar carcinoma, an endometrial carcinoma, a primary ovarian carcinoma, a metastatic ovarian carcinoma, a non-small cell lung cancer, a small cell lung cancer, a bladder cancer, a colon cancer, a primary, gastric adenocarcinoma, a primary colorectal adenocarcinoma, a renal cell carcinoma, and/or a prostate cancer. The compounds are represented by the following formula or a pharmaceutically acceptable salt thereof.

Abstract: The present invention relates to a RNA molecule comprising a first ribozyme, a first ligation sequence, an effector molecule, a second ligation sequence, and a second ribozyme. Methods of producing circular RNA molecules and treatment methods are also disclosed.

Abstract: Provided herein are methods of determining sensitivity to dose intense chemotherapy regimens based upon an index of estrogen receptor (ER)- and progesterone receptor (PR)-related genes, referred to as the sensitivity to endocrine therapy index (SETER/PR index). Further provided are methods of treating cancer patients determined to be sensitive to dose intense chemotherapy therapy by the SETER/PR index. Also provided herein are methods for determining prognosis based on the SET2,3 index.

Abstract: The present invention relates to, inter alia, a microfluidic device for capturing target cells and analyzing genomic DNA isolated from the target cells while under flow conditions. The microfluidic device includes a cell microchannel and a nucleic acid microchannel that intersect in an orthogonal manner, thereby forming a cell capture intersection region. The microfluidic device also includes a cell capture array and a nucleic acid entanglement array. The cell capture array includes a plurality of cell capturing micropillars and is located in the cell capture intersection region. The nucleic acid entanglement array includes a plurality of nucleic acid entanglement micropillars that function to physically entangle and maintain thereon genomic DNA isolated from the one or more target cell, and is located in a portion of the nucleic acid microchannel that is adjacent to and downstream of the cell capture intersection region. Methods of using the microfluidic device are also disclosed.

Abstract: Near-field coherent sensing (NCS) methods and systems are described herein. The techniques may be used to monitor vital signs is introduced herein. Multiple-input, multiple output near-field techniques may be used to characterize motion. In some embodiments, the methods and systems are used to measure cardiac motion. In some embodiments, the disclosed system is integrated into a seat, such as, for example, a car seat. The system be configured to monitor the vital signs of a seat occupant with multiple sensing points. The sensor can be integrated into the cushion and hence “invisible” to the user.

Abstract: The present application relates to method of vaccinating a subject against infection by an enveloped virus. The method includes providing a compound of the Formula (I) as described herein, and contacting the compound of Formula (I) with an isolated enveloped virus, having a membrane, to inactivate the membrane of the isolated enveloped virus. The subject is then treated with the enveloped virus having an inactivated membrane to vaccinate the subject against the enveloped virus. Further disclosed is an ex vivo vaccine composition including the compound of Formula (I) and an enveloped virus.

Abstract: A system for measuring synchrony between two or more regions, or within a single region, of a subject's brain. The system can include a signal conditioning module in communication with a phase extraction module. The signal conditioning module can receive an oscillating signal, bandpass filter the signal, and convert the signal to its real and imaginary components. The phase extraction module can receive the real and imaginary components, determine the quadrant of the oscillating signal on the complex plane based on the real and imaginary components, and determine the phase of the oscillating signal using a linear arctangent approximation based on the determined quadrant. The system can calculate synchrony metrics based on the determined phase.

Abstract: Solid-polymer electrolytes, methods of making solid-polymer electrolytes, and uses of solid-polymer electrolytes. A solid-polymer electrolyte comprises a cross-linked polymer network. A cross-linked polymer network may comprise a plurality of groups, which may be cross-linked groups, such as, for example, cross-linked difunctional polyether groups, cross-linked difunctional ionic groups, non-crosslinked groups, which may be referred to as “dangling” groups, or a combination thereof, and a plurality of cross-linked multifunctional crosslinker groups. A solid polymer electrolyte can be formed by polymerization. A solid polymer electrolyte can be formed in situ in a device. A solid polymer electrolyte can be used in devices such as, for example, batteries, supercapacitors, fuel cells, and the like.

Abstract: A method for controlling connectivity between two or more brain regions of a subject includes receiving signals corresponding to a connectivity between two or more regions of a subject's brain, measuring a connectivity level from the signals, and delivering at least one stimulation pulse to at least one target region of the subject's brain if the measured connectivity level is outside of a predetermined range.