Abstract: Technologies for radiomyography gesture recognition include a computing device coupled to a radio near-field sensor device including multiple transmitting and receiving antennas. The computing device transmits multiple radio frequency signals with the sensor device, which is positioned near the muscle area of interest for a user. The sensor device may include a cuff or armband that surrounds the forearm of the user. The computing device receives multiple time-domain signals with the receiving antennas and classifies the signals with a trained machine learning model to generate one or more distinct states, such as a gesture or posture classification. The computing device may transform each time-domain signal to a two-dimensional spectrogram and classify the two-dimensional spectrogram with a vision-based model such as a vision transformer model. Other embodiments are described and claimed.

Abstract: The disclosure provides a method of treating fibrosis of an organ comprising administering a c-P4H inhibitor to a patient suffering from fibrosis in an organ, to counteract pathological fibrosis. c-P4H inhibitors can be administered via various routes, including in an aerosolized state using a nebulizer, intravenous, intraperitoneal or subcutaneous injection.

Abstract: The invention provides compositions and methods for providing a cardioprotective effect in a subject. Specifically, the invention provides compositions and methods for treating cardiovascular ailments, for example, ischemia/reperfusion (I/R) injury, cardiac arrhythmias, oxidative stress, or cardiac failure by administering a retinoic acid receptor-beta (RAR?) agonist.

Abstract: The disclosed subject matter provides methods of synthesizing a helical graphene nanoribbon (hGNR), and electrode arrays and transistors based thereon. The method includes polymerizing a perylene tetraester precursor with an alkyne monomer to form a polymer backbone; inducing the polymer backbone to visible-light-mediated photocyclization to generate a helical nanoribbon precursor; and post-functionalizing the helical nanoribbon precursor with imide groups having oligoethylene glycol substituents, thereby forming a substantially defect-free helical graphene nanoribbon adapted for mixed ionic and electronic conduction.

Abstract: A plasmonic nanostructure includes a dielectric substrate, a periodic array of dielectric pillars on the dielectric substrate; and, on each dielectric pillar of the periodic array, a respective conductive layer. Each dielectric pillar of the periodic array of dielectric pillars is between the respective conductive layer and the dielectric substrate. A method for imaging a cell includes reflecting an optical beam off the plasmonic nanostructure. The plasmonic nanostructure has biological cells adhered thereto. The method also includes collecting the reflected optical beam with an optical detector.

Abstract: As described herein ingestion of high amounts of sugar, especially fructose, can increase the growth of intestinal tumors. Such cancer growth can be inhibited or prevented by limiting the amounts of sugar and amino acids ingested, by inhibiting ketohexokinase (KHK), fructose transport (via GLUT5), fatty acid synthesis (via FASN), phosphoinositide 3-kinases (PI3K), or by limiting amounts of sugar and amino acids ingested while also receiving KHK inhibitors, GLUT5 inhibitors, FASN inhibitors, PI3K inhibitors, or a combination of such inhibitors.

Abstract: A method in an illustrative embodiment comprises obtaining an acoustic signal for a given individual, generating an image representation of at least a portion of the acoustic signal, processing the image representation in at least one neural network of an acoustics classifier to generate a classification for the acoustic signal, and executing at least one automated action based at least in part on the generated classification. The acoustic signal illustratively comprises, for example, at least one of a heart sound signal, a blood flow sound signal, a lung sound signal, a bowel sound signal, a cough sound signal, or other physiological sound signal of the given individual. Generating the image representation illustratively comprises generating at least one spectrogram. Additionally or alternatively, generating the image representation may comprise generating one or more recurrence plots, Markov transition field image representations and/or Gramian angular field image representations.

Abstract: The disclosure provides a method of altering a DNA sequence, which method comprises the use of a type I-C CRISPR-Cas system based on Neisseria lactamica. The system involves a combination of two or more Neisseria lactamica proteins selected from Cas3, Cas5, Cas8c, and Cas7 and a synthetic guide RNA sequence.

Abstract: The invention relates to methods of lubricating biological tissue, such as joints, bone, ocular tissue, nasal tissue, tendons, tendon capsule, and vaginal tissue, by contacting the biological tissue with an effective amount of a block copolymer lubricating composition which functions at least or better than lubricin. In particular embodiments, the method is used to treat osteoarthritis. In specific embodiments, the block copolymer has an ammonium-containing polymer block and a non-ionic hydrophilic polymer block, or the copolymer has a carboxylic acid-containing polymer block and a non-acid non-ionic hydrophilic polymer block.

Abstract: Disclosed herein is the selective functionalization of one or more hydrocarbons ranging from the longest macromolecules to methane as the smallest. Functionalization is achieved through C—H activation of the one or more hydrocarbons and is carried out by the catalytic complex described herein. Also disclosed is the compound of formula (I) and the compound of formula (II).

Abstract: Provided are methods of increasing a response to a chemotherapeutic agent or an immunotherapeutic agent in a patient in need thereof, and methods of treating cancer in a patient in need thereof, comprising administering to the patient a chemotherapeutic agent or an immunotherapeutic agent and a metastasis inhibiting compound, as described in this disclosure.

Abstract: The present technology is directed to nanoparticle compositions and methods useful in treating RHAMM-positive cancers.

Abstract: The present disclosure is directed to a method that involves selecting a subject having a primary tumor and obtaining, from the selected subject, a sample containing exosomes derived from primary tumor cells. The exosomes are isolated from the sample and expression levels of cell migration-inducing and hyaluronan-binding protein (CEMIP) are detected in the isolated exosomes.

Abstract: A gene therapy vector comprising an expression cassette coding for a mammalian apolipoprotein E that has a residue other than arginine at at least one of positions 112, 136, or 158, but is not a mammalian apolipoprotein E that has R112, R136 and R158 or a mammalian apolipoprotein E that has C112, R136 and C158, or coding for an antibody that binds to APOE4 or disrupts the binding of APOE to heparan sulfate proteoglycans, and methods of using the vector, are provided.

Abstract: An integrated circuit includes a programmable reflective load line that includes main delay segments arranged in series between an input of the programmable reflective load line and ground, variable delay modules arranged in parallel between nodes adjoining the main delay segments and ground, and main switches, with each main switch arranged between one of the variable delay modules and one of the nodes adjoining the main delay segments. Each variable delay module includes sub-delay segments arranged in series between the associated main switch and ground. Each variable delay module also includes one or more sub-delay switches, with each sub-delay switch arranged between a node adjoining two of the associated sub-delay segments and ground. The integrated circuit may further include a hybrid coupler arranged with the programmable reflective load line and another programmable reflective load line as a reflective-type phase-shifter.

Abstract: A data communication device includes a battery having a first flowable electrolyte. In some embodiments, the battery is a redox flow battery (RFB) or a hybrid RFB. A first channel contains the first flowable electrolyte of the battery (i.e., contains at least a portion of the first flowable electrolyte). The first channel may include a tube and/or a reservoir. At least a portion of the first channel may be flexible and/or stretchable. The first channel has a first electrode configured to impart and/or receive a first electrical signal in the first flowable electrolyte. The first electrical signal may be a digital signal. The first electrical signal may be an encoded signal. The device may include a transceiver in electronic communication with the first electrode.

Abstract: The invention provides: imidazole and imidazolium compounds of formulas (I) and (II): polymers containing a plurality of imidazolium-containing repeating units of formula (III?): and membranes and devices comprising the polymers. Also provided are methods of making the inventive compounds and polymers.

Abstract: The present disclosure includes a method of producing solid inorganic carbonate compounds by capturing, converting, and storing carbon dioxide comprising providing one or more precursor compound; providing one or more carbon dioxide capture solvent or capture additive; and reacting said one or more precursor compound with said one or more carbon dioxide capture solvent or capture additive under conditions effective to produce one or more solid inorganic carbonate compound. Also disclosed is a method of producing solid inorganic bicarbonate compounds by capturing, converting, and storing carbon dioxide comprising providing one or more precursor compound; providing one or more carbon dioxide capture solvent or capture additive; and reacting said one or more precursor compound with said one or more carbon dioxide capture solvent or capture additive under conditions effective to produce one or more solid inorganic bicarbonate compound.

Abstract: An apparatus in one embodiment comprises a processing platform having at least one processing device. The processing platform implements a trusted bridge configured for at least temporary coupling between one or more data sources and a smart contract program of a blockchain. The trusted bridge comprises a secure enclave component and a relay component. Data obtained from a given one of the data sources via the relay component of the trusted bridge is authenticated in the secure enclave component of the trusted bridge. Information based at least in part on the data authenticated in the secure enclave component of the trusted bridge is provided to the smart contract program of the blockchain via the relay component of the trusted bridge. The secure enclave component illustratively receives a request for authenticated data from the blockchain smart contract program via the relay component, and responds to the request via the relay component.

Abstract: The present technology is directed to compounds, compositions, medicaments, and methods related to the treatment of cancers expressing PSMA. The compounds are of Formulas I & II or pharmaceutically acceptable salts thereof. The present technology is especially well-suited for use in treating prostate cancer.