Patents Assigned to Council of Scientific and Industrial Research
  • Transgenic plants with enhanced chlorophyll content and salt tolerance
    Patent number: 6791009
    Abstract: The present invention relates to novel nucleic acid construct comprising (a) an anti-sense gene of a sense gene encoding E. histolytica calcium binding protein or a portion of said anti-sense gene, wherein said sense gene is at least 90% similar to the nucleic sequence of SEQ ID No: 1, and wherein said portion of the anti-sense gene is of a size capable of disrupting translation of said calcium binding protein; and (b) a constitutive promoter and a nopaline synthase (nos) polyadenylation signal sequence both operatively linked to said gene or portion thereof; wherein said construct is useful for increasing the level of chlorophyll in plants, a transgenic plant containing said construct and a novel nucleic acid construct useful for developing stress-tolerant plants, comprising (a) a sense gene encoding E.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: September 14, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Girdhar Kumar Pandey, Vanga Siva Reddy, Renu Deswal, Alok Bhattacharya, Sudhir Kumar Sopory
  • Process for generation of precipitated calcium carbonate from calcium carbonate rich industrial by-product
    Patent number: 6790424
    Abstract: An environmentally friendly process for the production of precipitated calcium carbonate suitable for industrial application from a calcium carbonate-rich by-product of a nitrophosphate fertilizer plant. The process employs purification steps of calcination, carbonation and optional treatment with an emulsion of fatty acid or fatty acid derivatives.
    Type: Grant
    Filed: October 31, 2001
    Date of Patent: September 14, 2004
    Assignees: Council of Scientific and Industrial Research, Gujarat Narmada Valley Fertilizer Company Limited
    Inventors: Raksh Vir Jasra, Pravinchandra M. Oza, Rajesh S. Somani, Jatin R. Chunnawala, Mrinal V. Sheth, Vikram V. Thakkar, Yogi M. Badheka, Jayalekshmy Ayyer, Virendra B. Patel
  • Process for vapor phase nitration of benzene using nitric acid over molybdenum silica catalyst
    Patent number: 6791000
    Abstract: Nitration of benzene is an important reaction for the production of nitro benzene, which is an important intermediate in chemical and pharmaceutical industries. Conventionally nitrobenzene is produced by liquid phase reactions employing mixed acids. A sulfuric acid/nitric acid mixture is the most commonly used nitrating agent. Generation of large amount dilute sulfuric acid, organic wastes and products of their neutralization makes the benzene nitration a environmentally harmful process. The present process enables the preparation of nitrobenzene by vapor phase nitration of benzene over solid acid catalyst, MoO3/SiO2 using nitric acid. This process is a clean and environment friendly process without use of sulphuric acid.
    Type: Grant
    Filed: May 30, 2003
    Date of Patent: September 14, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Mohan Keraba Dongare, Pratap Tukaram Patil, Kusum Madhukar Malshe
  • In vitro production of amoebocytes from tachypleus gigas in leibovitz culture medium
    Patent number: 6790659
    Abstract: The present invention provides a process for large scale in vitro production of amoebocytes of Indian Horseshoe Crab (Tachypleus gigas) (T. gigas) from dissected gill flaps of T. gigas, in Leibovitz L-15 culture medium concentration (2×), to provide enhanced generation of amoebocytes. The process comprises the steps of: dissecting gill flaps of T. gigas; washing the gill flaps with an antibiotic solution followed by alcohol; culturing the gill flaps in tissue culture plates of sterile saline on a Rocker platform; culturing further the gill flaps in Leibovitz L-15 culture medium (2×); purging the gill flaps with Tween 80 solution; and purging again the gill flaps with horseshoe crab serum, while keeping the gill flaps in the culture medium viable for 90 days by feeding with fresh medium at an interval of 10-15 days to enable the enhanced release of amoebocytes both within and outside the gill flaps.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: September 14, 2004
    Assignees: Council of Scientific and Industrial Research, National Center for Cell Sciences
    Inventors: Ramesh Ramchandra Bhonde, Anil Chatterji
  • 1,1-bis(4-aminophenyl)-3-alkylcyclohexanes and method of preparation thereof
    Patent number: 6790993
    Abstract: The present invention relates to new aromatic diamines. More particularly, the present invention relates to new aromatic diamines prepared from cashew nut shell liquid (CNSL), which is a renewable resource material. The present invention particularly relates to novel 1,1-bis(4-aminophenyl)-3-alkylcyclohexanes and to a method for their preparation.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: September 14, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Rahul Diliprao Shingte, Prakash Purushottam Wadgaonkar
  • Indolicidin analogs with anti-microbial activity
    Publication number: 20040176300
    Abstract: The present invention relates to three single tryptophan analogs ILPWKLPLLPLRR-amide (IL4), ILPLKLPWLPLRR-amide (IL8) and ILPLKLPLLPWRR-amide (IL11), of indolicidin, a cationic tridecapeptide amide found in the granules of bovine neutrophils, said analogs having said amino acid only at 4th, 8th or 11th position from N-terminal, with leucine at its all other conventional positions, said analogs selectively having only anti-microbial activity and no hemolytic activity of Indolicidin, and thereby providing therapeutic options and a method thereof.
    Type: Application
    Filed: March 25, 2002
    Publication date: September 9, 2004
    Applicant: Council of Scientific and Industrial Research
    Inventors: Chilukuri Subbalakshmi, E. Bikshapathy, Narasimhaiah Sitaram, Ramakrishnan Nagaraj
  • Modified and efficient process for the production of standardized pudina arka
    Publication number: 20040175446
    Abstract: A modified and efficient single-step process for the production of standardized pudina arka as medicated water from plant Mentha herbs with ratio of drug component in arka to total arka ranging between 1:2 to 1:20 involving complete recovery of all the active material, said method comprising steps of taking aerial parts of the plant Mentha herb, crushing it optionally, adding solvent to the plant parts in the ratio ranging between 6:1 to 25:1 to obtain mixture, macerating the mixture at an elevated temperature, while maintaining desired pH, and pressure conditions, distillating the macerated mixture continuously till requisite amount of distillate is obtained, and obtaining distillate as standard pudina arka.
    Type: Application
    Filed: March 7, 2003
    Publication date: September 9, 2004
    Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
    Inventors: Shri Gopal Agarwal, Rajinder Kumar Thappa, Bal Krishan Kapahi, Aruna Gupta, Om Parkash Suri, Ghulam Nabi Qazi
  • Bacteriophage, a process for the isolation thereof, and a universal growth medium useful in the process thereof
    Patent number: 6787360
    Abstract: The present invention provides a isolated bacteriophage useful as a tool for studying biological, biochemical, physiological and genetic properties of actinomycetes and other organisms which comprises a novel strain of Saccharomonospora having certain specified characteristics. The invention also relates to a process for the isolation of the said bacteriophage and/or DNA phage and to a novel universal growth medium which is particularly useful in the said process. Another embodiment of the process relates to a clonong vector which comprises a plasmid or bacteriophage comprising the phage DNA of the invention.
    Type: Grant
    Filed: May 13, 2002
    Date of Patent: September 7, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Pushpa Agrawal, Vishal Soni
  • (+)-1-Bisabolone isolated from cymbopogon flexuosus and antibacterial activity thereof
    Patent number: 6787674
    Abstract: The present invention relates to anti-microbial activity of the essential oil of Cymbopogon flexuosus (Nees ex Steud) Wats and the process of isolation of novel sesquiterpene compound which is mainly responsible for the strong anti-microbial/anti-bacterial activity. The present invention particularly relates to anti-bacterial activity of the essential oil and a pure isolate identified as (+)-1-bisabolone of formula 1 against gram positive bacteria from a strain of a grass identified as Cymbopogon flexuosus.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: September 7, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Subhash Chandra Taneja, Ashok Kumar Shahi, Vijeshwar Verma, Vijay Kumar Sethi, Samar Singh Andotra, Abid Zaffar Hashmi, Prabhu Dutt, Sanotosh Kumar Bakshi, Maharaj Krishan Koul, Satya Narayan Sharma, Suresh Chandra, Ghulam Nabi Qazi
  • Process for the preparation of dinitramidic acid and salts thereof
    Patent number: 6787119
    Abstract: The present invention provides an ecofriendly method for preparing dinitramidic acid and its salts by nitration of ammonium sulfamate with fuming nitric acid as a nitrating agent using solid acid catalysts selected from the group consisting of a montmorillonite clay catalyst and metal ion exchanged K10 montmorillonite clay catalysts and surface supported catalysts and preparation of ammonium dinitramide by neutralization of the dinitramidic acid with ammonia and separation of ammonium dinitramide.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: September 7, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Boyapati Manoranjan Choudary, Mannepalli Lakshmi Kantam, Katuri Jeeva Ratnam, Vijayakumar Karasala, Sridhar Chidara, Venkatachalam Subbiah, Santosh Gopalakrishnan, Ramaswamy Rajagopalan, Ninan Ninan Kovoor, Kuchibhatla Sitarama Sastri
  • Controlled thruster driven profiler for coastal waters
    Patent number: 6786087
    Abstract: The present invention relates to a device useful as a controllable variable speed thruster-driven oceanographic profiler for coastal waters for measuring the vertical structure of chosen properties of the oceanic water column.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: September 7, 2004
    Assignee: Council of Scientific & Industrial Research
    Inventors: Elgar Stephen Desa, Prakash Mehra, Gajanan Purushottam Naik, Bailon Antonio Ehrlich Desa, Rajachandran Madhan, Antonio Manuel Dos Santos Pascoal
  • Process for the preparation of a vaccine for the treatment of tuberculosis and other intracellular infections diseases and the vaccine produced by the process
    Patent number: 6783765
    Abstract: The present invention relates to a process for the preparation of a vaccine against tuberculosis and other intracellular pathogens, this vaccine is targeted against intracellular pathogens, more particularly the pathogen Mycobacterium tuberculosis and Salmonella in this case.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: August 31, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Javed Naim Agrewala, Naresh Sharma
  • Process for the preparation of metal sulfide nanoparticles
    Patent number: 6783963
    Abstract: The process of the invention reports a new biological method, instead of chemical or physical methods, for preparing colloidal nano-sized metal sulphides using fungi.
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: August 31, 2004
    Assignee: Council of Scientific & Industrial Research
    Inventors: Priyabrata Mukherjee, Deendayal Mandal, Absar Ahmad, Murali Sastry, Rajiv Kumar
  • Ready-to-dilute sugarcane juice beverage powder and a process for preparing the same
    Patent number: 6783785
    Abstract: The present invention relates to a ready-to-dilute sugarcane juice beverage powder and a process for preparing the same and more particularly, the present invention describes a ready-to-dilute sugarcane juice beverage powder containing 80 to 95% by wt. dry sugarcane juice, 5 to 15% by wt. acacia pulvis, 0.01 to 0.10% by wt. of a heteropolysaccharide, 1-2% by wt. of one more anti-caking agents and 0.1 to 0.5% by wt of food preservatives and optionally 0.05 to 0.5% by wt. sodium alginate and a process for the same using a vacuum shelf dryer.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: August 31, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Bashyam Raghavan, Kulathooran Ramalakshmi, Babasaheb Bhaskarrao Borse, Mysore Nagarajarao Ramesh, Vishweshwaraiah Prakash
  • Process for the isolation of a major harmful oxidant from cigarette smoke
    Patent number: 6782891
    Abstract: The components of cigarette smoke, known until now, do not explain the overwhelming hazardous effects of smoking; this invention describes the isolation, identification and procedures for determination of the structure, properties and assay of a relatively stable major harmful oxidant (cs-oxidant) present in the cigarette smoke, the content of which is about 190±10 &mgr;g per cigarette; the cs-oxidant alone almost quantitatively accounts for the oxidative damage of proteins produced by the aqueous extract of whole cigarette smoke, it is also responsible for the oxidative damage of DNA; since the cs-oxidant is relatively stable, it further explains the deleterious effects of the side stream smoke and passive smoking; a number of chemical compounds/agents including vitamin C have been found to prevent the cs-oxidant induced protein oxidation in vitro.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: August 31, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventor: Indu Bhusan Chatterjee
  • MULTIFUNCTIONAL CATALYST USEFUL IN THE SYNTHESIS OF CHIRAL VICINAL DIOLS AND PROCESS FOR THE PREPARATION THEREOF, AND PROCESS FOR THE PREPARATION OF CHIRAL VICINAL DIOLS USING SAID MULTIFUNCTIONAL CATALYSTS
    Patent number: 6780810
    Abstract: The present invention relates to a multifunctional reusable catalyst and to a process for the preparation thereof on a single matrix of the support to perform multicomponent reaction in a single pot. The multifunctional catalysts of the invention are useful for the synthesis of chiral vicinal diols by tandem and/or simultaneous reactions involving Heck coupling, N-oxidation and AD reaction of olefins in presence of cinchona alkaloid compounds both as an native one and immobilized one in the said matrix support. This invention also relates to a process for preparing vicinal diols by asymmetric dihydroxylation of olefins in presence of cinchona alkaloid compounds employing reusable multifunctional catalysts as heterogeneous catalysts in place of soluble osmium catalysts.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: August 24, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Boyapati Manoranjan Choudary, Naidu Sreenivasa Chowdari, Sateesh Madhi, Mannepalli Lakshmi Kantam
  • Process for the preparation of optically active azabicyclo heptanone derivatives
    Patent number: 6780635
    Abstract: The present invention provides a process for preparation of optically active azabicyclo heptanone derivates using lactamases that will react with racemic lactam of formula (I) to give a single enanotiomer of lactam (III) and the corresponding ring opened compound of formula (IV) in an enantiomerically pure form.
    Type: Grant
    Filed: December 27, 2001
    Date of Patent: August 24, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Rohini Ramesh Joshi, Asmita Ashutosh Prabhune, Ramesh Anna Joshi, Mukund Keshav Gurjar
  • Antioxidant from natural source
    Patent number: 6781002
    Abstract: The invention relates to a process for the isolation of (−)-mesquitol in substantial (1.5%) yields from Dichrostachys cinerea and also the usage of (−)-mesquitol as an antioxidant/free-radical scavenger.
    Type: Grant
    Filed: February 28, 2003
    Date of Patent: August 24, 2004
    Assignee: Council of Scientific & Industrial Research
    Inventors: Janaswamy Madhusudana Rao, Rao Jagadeeshwar Rao, Ashok Kumar Tiwari, Jhillu Singh Yadav, Kondapuram Vijaya Raghavan
  • 8-(C-&bgr;-D-glucopyranosyl)-7, 3', 4'-trihydroxyflavone, process of isolation thereof, pharmaceutical composition and method for the treatment of diabetes
    Patent number: 6777392
    Abstract: The present invention relates to a novel compound 8-(C-&bgr;-D-glucopyranosyl)-7,3′,4′-trihydroxyflavone, isolated from Pterocarpus marsupium useful in the treatment of diabetes. The present invention also relates to a method for the preparation of the compound and to the uses thereof.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: August 17, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Rakesh Maurya, Sukhdev Swami Handa, Rajinder Singh
  • Process for synthesis of bis-(substituted-4-quinolyl) disulphides
    Patent number: 6777553
    Abstract: The present invention relates to a process for the synthesis of bis-(substituted-4-quinolyl) disulphides.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: August 17, 2004
    Assignee: Council of Scientific and Industrial Research
    Inventors: Harshadas Mitaram Meshram, Premalatha Kokku, Venkata Madhavi Ayyagiri, Eshwaraiah Begari, Jhillu Singh Yadav