Patents Assigned to Curators of the University
  • Compounds for treating papilloma virus infection
    Patent number: 8993609
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells and subjects infected with papilloma virus.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: March 31, 2015
    Assignees: Nanovir, LLC, The Curators of the University of Missouri
    Inventors: James K. Bashkin, Kevin J. Koeller, Terri Grace Edwards, Christopher Fisher
  • WAVEGUIDE PROBE FOR NONDESTRUCTIVE MATERIAL CHARACTERIZATION
    Publication number: 20150077138
    Abstract: An open-ended waveguide probe including a finite flange extending outwardly and functioning as an infinite flange. A signal source provides a microwave signal to the waveguide, which in turn transmits microwave electromagnetic energy incident upon an object to be tested. The finite flange at the waveguide's aperture is shaped to reduce scattering of the electromagnetic field reflected from the object and received by the aperture. The probe is adapted for coupling to a receiver for sampling the reflected electromagnetic field received by the aperture and the receiver is adapted for coupling to a processor for determining at least one material characteristic of the object based on sampled electromagnetic field reflected from the object.
    Type: Application
    Filed: September 13, 2013
    Publication date: March 19, 2015
    Applicant: The Curators of the University of Missouri
    Inventors: Mohammad Tayeb Ghasr, Matthew Kempin, Reza Zoughi
  • CLUSTER BORON COMPOUNDS AND USES THEREOF
    Publication number: 20150072956
    Abstract: The present invention relates to novel cluster boron compounds and their use as sodium channel blockers. In particular, the novel cluster boron compounds may be lidocaine analogs where the aromatic ring of the lidocaine molecule is replaced with a cluster boron group. The invention also provides methods for making the cluster boron compounds comprising contacting a halogenated cluster boron with an amino acetamide in the presence of a catalyst, a proton acceptor, and a ligand.
    Type: Application
    Filed: September 13, 2012
    Publication date: March 12, 2015
    Applicant: The Curators of the University of Missouri
    Inventors: George R. Kracke, Yulia Sevryugina, Marion Frederick Hawthorne
  • SYSTEMS AND METHODS FOR DIAGNOSIS AND TREATMENT OF PSYCHIATRIC DISORDERS
    Publication number: 20150056595
    Abstract: A device for diagnosing and treating psychiatric disorders is described. The device may be configured to provide a graphical user interface that enables a user to select at least one of: entering information related to a diagnosis of the psychiatric disorder and alleviating symptoms caused by the psychiatric disorder. Upon a user selecting entering information related to the diagnosis of a psychiatric disorder, the device may receive information related to the diagnosis of the psychiatric disorder. The device may determine the severity of a user's condition based at least in part on the received information. The device may provide a treatment based on the determined severity of the user's condition. A treatment may include providing feedback to a user.
    Type: Application
    Filed: August 23, 2013
    Publication date: February 26, 2015
    Applicant: The Curators of the University of Missouri
    Inventors: Ganesh GOPALAKRISHNA, Sriram CHELLAPPAN
  • Active cooling of high speed seeker missile domes and radomes
    Patent number: 8933860
    Abstract: A thermal management system and method for active cooling of high speed seeker missile domes or radomes comprising bonding to an IR dome or RF radome a heat pipe system having effective thermal conductivity of 10-20,000 W/m*K and comprising one or more mechanically controlled oscillating heat pipes, employing supporting integrating structure including a surface bonded to the IR dome or RF radome that matches the coefficient of thermal expansion the dome or radome material and that of said one or more mechanically controlled oscillating heat pipes, and operating the heat pipe system to cool the IR dome or RF radome while the missile is in flight.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: January 13, 2015
    Assignees: Integral Laser Solutions, Inc., The Curators of the University of Missouri
    Inventors: LaVerne Arthur Schlie, Hongbin Ma
  • Method and system for purifying charged radioisotopes
    Patent number: 8932876
    Abstract: The present invention provides a simple and inexpensive method for removing metal and other impurities in a radioisotope solution. The invention further includes the development of a new parent/daughter generator system for collecting the daughter isotope in a concentrated solution.
    Type: Grant
    Filed: May 11, 2009
    Date of Patent: January 13, 2015
    Assignee: The Curators of the University of Missouri
    Inventors: Cathy Sue Cutler, Gary John Ehrhardt, Hendrik Petrus Engelbrecht, Delbert E. Day
  • High surface area carbon and process for its production
    Patent number: 8926932
    Abstract: The present invention provides a high surface area porous carbon material and a process for making this material. In particular, the carbon material is derived from biomass and has large mesopore and micropore surfaces that promote improved adsorption of materials and gas storage capabilities.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: January 6, 2015
    Assignee: The Curators of the University of Missouri
    Inventors: Peter Pfeifer, Galen J. Suppes, Parag Shah, Jacob W. Burress
  • SOYBEAN RESISTANT TO CYST NEMATODES
    Publication number: 20140380522
    Abstract: A transgenic soybean plant or parts thereof, resistant to soybean cyst nematodes, transformed to express Glyma18g02570, Glyma18g02580, or Glyma18g02590, or a variant thereof. Also provided is a method of making such a plant. Also provided is an artificial DNA construct encoding Glyma18g02570, Glyma18g02580, or Glyma18g02590, or a variant thereof.
    Type: Application
    Filed: March 18, 2014
    Publication date: December 25, 2014
    Applicants: The Curators of the University of Missouri, Board of Trustees of Southern Illinois University
    Inventors: Melissa G. Mitchum, David Lightfoot, Pramod Kaitheri Kandoth, Shimming Liu, Khalid Meksem
  • Method and system for purifying charged radioisotopes
    Publication number: 20140369903
    Abstract: The present invention provides a simple and inexpensive method for removing metal and other impurities in a radioisotope solution. The invention further includes the development of a new parent/daughter generator system for collecting the daughter isotope in a concentrated solution.
    Type: Application
    Filed: May 11, 2009
    Publication date: December 18, 2014
    Applicant: the Curators of the University of Missouri
    Inventors: Cathy Sue Cutler, Gary John Ehrhardt, Hendrik Petrus Engelbrecht, Delbert E. Day
  • Dielectric loaded fluids for high voltage switching
    Patent number: 8912460
    Abstract: This disclosure relates to methods and systems to reduce high voltage breakdown jitters in liquid dielectric switches. In particular, dielectric liquids have been produced that contain a suspension of nanoparticles and a surfactant to reduce the breakdown jitter. In one embodiment, the suspended nanoparticles are Barium Strontium Titanate (BST) nanoparticles.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: December 16, 2014
    Assignee: The Curators of the University of Missouri
    Inventors: Randy D. Curry, Christopher Yeckel, Daniel Crosby
  • Transgenic pig model of cystic fibrosis
    Patent number: 8912386
    Abstract: The present invention provides transgenic, large non-human animal models of diseases and conditions, as well as methods of making and using such animal models in the identification and characterization of therapies for the diseases and conditions.
    Type: Grant
    Filed: November 3, 2011
    Date of Patent: December 16, 2014
    Assignees: University of Iowa Research Foundation, The Curators of the University of Missouri
    Inventors: Michael J. Welsh, Christopher S. Rogers, Randall S. Prather, John Engelhardt, Ziying Yan
  • INORGANIC PYROPHOSPHATE AND USES THEREOF
    Publication number: 20140350329
    Abstract: The present invention provides a new and improved sperm stimulating additive comprising a certain amount of inorganic pyrophosphate (PPi). Addition of PPi in the media for human/animal in vitro fertilization (IVF) improves fertilization rate; addition of PPi in the semen extender for farm animal artificial insemination (AI) may improve pregnancy rates; furthermore, mamalian oocytes matured in vitro in a medium including PPi attain improved fertilization and developmental potential, while embryos cultured in medium supplemented with PPi have improved development to blastocyst.
    Type: Application
    Filed: May 29, 2014
    Publication date: November 27, 2014
    Applicant: The Curators of the University of Missouri
    Inventors: Peter Sutovsky, Young-Joo Yi
  • High dielectric constant composite materials and methods of manufacture
    Patent number: 8889776
    Abstract: The present invention relates to composite materials with a high dielectric constant and high dielectric strength and to methods of producing the composite materials. The composite materials have high dielectric constants at a range of high frequencies and possess robust mechanical properties and strengths, such that they may be machined to a variety of configurations. The composite materials also have high dielectric strengths for operation in high power and high energy density systems. In one embodiment, the composite material is composed of a trimodal distribution of ceramic particles, including barium titanate, barium strontium titanate (BST), or combinations thereof and a polymer binder.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: November 18, 2014
    Assignee: The Curators of the University of Missouri
    Inventors: Randy D. Curry, Kevin O'Connor
  • Anonymized video analysis methods and systems
    Patent number: 8890937
    Abstract: Methods and systems for anonymized video analysis are described. In one embodiment, a first silhouette image of a person in a living unit may be accessed. The first silhouette image may be based on a first video signal recorded by a first video camera. A second silhouette image of the person in the living unit may be accessed. The second silhouette image may be of a different view of the person than the first silhouette image. The second silhouette image may be based on a second video signal recorded by a second video camera. A three-dimensional model of the person in voxel space may be generated based on the first silhouette image, the second silhouette image, and viewing conditions of the first video camera and the second video camera. In some embodiments, information on falls, gait parameters, and other movements of the person living unit are determined. Additional methods and systems are disclosed.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: November 18, 2014
    Assignee: The Curators of the University of Missouri
    Inventors: Marjorie Skubic, James M. Keller, Fang Wang, Derek T. Anderson, Erik Edward Stone, Robert H. Luke, III, Tanvi Banerjee, Marilyn J. Rantz
  • Total internal reflection photoacoustic spectroscopy
    Patent number: 8891088
    Abstract: A system and method of conducting total internal reflection photoacoustic spectroscopy (TIRPAS) comprising using a pulsed laser source to emit a thermally or stress confined laser beam at a prism comprising a surface to be in contact with a sample such that the laser beam travels through the prism to a location at an interface between the prism and the sample to form an evanescent field extending into the sample to generate a detectable photoacoustic response to the evanescent field by an analyte in the sample.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: November 18, 2014
    Assignee: The Curators of the University of Missouri
    Inventors: Benjamin Samuel Goldschmidt, Amanda Susan Martin Sudduth, Paul James Douglas Whiteside, John Andrew Viator
  • Organosilica nanoparticles and method for making
    Patent number: 8873918
    Abstract: Preparation of Free-Flowing Organosilica Nanoparticles by Forming a solution of an organosilica nanoparticle precursor in a mixed solvent system comprising a first solvent and a second solvent, wherein the first solvent is different from the second solvent, wherein the second solvent has a boiling point which is greater than a boiling point of the first solvent, and wherein the nanoparticle precursor has a greater solubility in the first solvent than in the second solvent; removing at least 50% of the first solvent to form nanoparticles having a mean particle size less than about 25 nanometers dispersed in the solution; adding a coupling agent to the solution to facilitate reacting of the coupling agent with the nanoparticles; and recovering the nanoparticles from the solution, wherein the recovered nanoparticles have the mean particle size of less than about 25 nanometers
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: October 28, 2014
    Assignee: The Curators of the University of Missouri
    Inventors: Venumadhav Korampally, Shubhra Gangopadhyay, Sangho Bok, Keshab Gangopadhyay
  • CAPILLARY WALL COUPLED WHISPERING GALLERY MODE MICRORESONATOR
    Publication number: 20140314375
    Abstract: A microresonator structure comprises a waveguide and a microsphere. The waveguide is of elongated cylindrical shape and includes a first section of optical transmission material and a cavity section axially aligned with the first section. The cavity section includes a first cavity and a second cavity. The first cavity is adjacent to the first section and includes a first sidewall of optical transmission material with an inner surface that tapers inward to an apex positioned adjacent to the first section. The second cavity is positioned adjacent to the first cavity of hollow cylindrical shape and includes a circumferential second sidewall of optical transmission material that abuts the first sidewall. The microsphere has a spherical outer surface and is positioned within the cavity section such that the outer surface contacts a portion of the first sidewall and a portion of the second sidewall.
    Type: Application
    Filed: April 22, 2013
    Publication date: October 23, 2014
    Applicant: The Curators of the University of Missouri
    Inventors: Hai Xiao, Hanzheng Wang
  • Encoded Nanopore Sensor for Multiplex Nucleic Acids Detection
    Publication number: 20140309129
    Abstract: The present invention provides a new and improved multiplexed oligonucleotide detection method based on the nanopore technology with one or more probes containing a sequence with complementarity to the target oligonucleotide, a terminal extension at the probe's 3? terminus, 5? terminus, or both termini and a label attached to the terminus. The improved probes and probe sets enable sensitive, selective, and direct multiplex detection, differentiation and quantification of distinct target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method based on miRNA levels in the patient's tissue sample.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 16, 2014
    Applicant: The Curators of the University of Missouri
    Inventors: Li-Qun Gu, Xinyue Zhang
  • Patterning of ultra-low refractive index high surface area nanoparticulate films
    Patent number: 8859050
    Abstract: A method for forming a nanoporous film pattern on a substrate comprising imparting differential surface energy to a surface of a substrate to define first areas having a first surface energy conducive to maintenance of a nanoporous film thereon and second areas having a second surface energy non-conducive to maintenance of a nanoporous film thereon, said first and second areas defining a differential surface energy pattern on the substrate; depositing a nanoporous film precursor onto the differential surface energy pattern; and curing the nanoporous film precursor to form the nanoporous film pattern.
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: October 14, 2014
    Assignee: The Curators of the University of Missouri
    Inventors: Venumadhav Korampally, Shubhra Gangopadhyay, Keshab Gangopadhyay
  • Omeprazole solution and method for using same
    Patent number: RE45198
    Abstract: A pharmaceutical composition includes an aqueous solution/suspension of omeprazole or other substituted benzimidazoles and derivatives thereof in a pharmaceutically acceptable carrier comprising a bicarbonate salt of a Group IA metal. A method for treating and/or preventing gastrointestinal conditions by administering to a patient a pharmaceutical composition including an aqueous solution/suspension of omeprazole or other substituted benzimidazoles and derivatives thereof in a pharmaceutically acceptable carrier including a bicarbonate salt of a Group IA metal wherein the administering step consists of a single dosage form without requiring further administering of the bicarbonate salt of the Group IA metal.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: October 14, 2014
    Assignee: The Curators of The University Of Missouri
    Inventor: Jeffrey O. Phillips