Abstract: A hinge assembly comprising a first hinge leaf assembly and a second hinge leaf assembly, each having their respective hinge leaf. The hinge assembly further comprises at least one mounting member fixable to a moveable barrier through a fixing arrangement. The first and/or second hinge leaf is connectable to the at least one mounting member so as to be adjustable relative thereto. A locking arrangement is also included to releasably lock the first and/or second hinge leaf to the at least one mounting member. The locking arrangement is operative to adopt a hold condition where relative movement between the first and/or second hinge leaf and the at least one mounting member is prevented, and a released condition where the first and/or second hinge leaf is able to be adjusted relative to the at least one mounting member.

Abstract: An automated window mechanism having an electric motor attached to a sliding panel of a window configured to open and close the window by moving the sliding panel. The electric motor has a locked state in which the electric motor and sliding panel are stationary. The automated window mechanism also includes a monitor configured to detect an external force applied to the sliding panel while the electric motor is in the locked state. In response to the monitor detecting the external force while the electric motor is in the locked state, the positive lead and the negative lead are grounded, rendering the electric motor an electric brake. A method and system for preventing unwanted movement of an automated window are also disclosed.

Abstract: Systems for flight simulation, and methods for operating the same. The system may include a 6 degree of freedom devices, a multi-point harness configured to suspend a user above a ground surface, and a sensor circuit integrated with a user-facing surface of the multi-point harness to detect changes in distribution of weight across the user-facing surface. The system includes a processor coupled to the sensor circuit, where the processor may be configured to: detect a shift in weight distribution across the user-facing surface of the multi-point harness. The processor may generate at least one virtual physics parameter associated with the detected shift in weight distribution. The at least one virtual physics parameter representing a force associated with a change in center of gravity of the user. The processor may modulate the 6 DOF device to orient the multi-point harness based on at least one virtual physics parameter to simulate a resultant trajectory of the user during the flight simulation.

Abstract: The present invention discloses an electrolyzed water generation device. An electrolyzed water generation device that automatically generates set electrolyzed water is configured according to the present invention. By the electrolyzed water generation device, electrolyzed water having a target concentration ranging from a low concentration to a high concentration can be generated, various types of electrolyzed water that fit different purposes can be generated through compact design, and efficiency of electrolyzed water generation can be improved using low power.

Abstract: The present invention relates to a liquid formulation comprising a VEGF receptor fusion protein at a concentration of at least 100 mg/ml, and wherein the formulation comprises: i) no buffering agent, ii) a citrate buffer, or iii) a histidine buffer preferably without sucrose and preferably with methionine. In addition, the invention relates to an article of manufacture comprising a container with such liquid formulation as well as the use of the liquid formulation for a method of treatment.

Abstract: Medical devices and methods of use thereof are described. The device may include a body having a housing that defines a lumen, a piston within the housing, and an actuator operably coupled to the piston, wherein the piston is movable along the lumen by operating the actuator. The device also may include a cartridge insertable into the body and/or a flexible fitting configured for direct application to an eye of a subject.

Abstract: An automated window mechanism includes a motor attached to a sliding window and a rack on a window frame. A transmission couples the motor to the rack such that rotation of the motor causes the transmission to move the sliding window relative to the rack. The mechanism also includes a clutch switch assembly, that includes a switch and a clutch actuator responsive to the switch and being configured to engage and disengage the motor to the rack. The mechanism also includes a position sensor coupled to the transmission and configured to monitor a position of the sliding window relative to the frame using the transmission. The position sensor continues to monitor the rotational position of the transmission when the transmission is engaged and when the transmission is disengaged.

Abstract: An automated window mechanism is disclosed, including a motor secured to a window, the window being in a frame and wherein the motor causes the window to move relative to the frame in two directions: an open direction being defined as a direction toward which movement of the window relative to the frame causes the window to be more closed, and a closed direction defined as a direction opposite the open direction. The mechanism also includes a transmission component that transfers power from the motor to movement of the window relative to the frame, the transmission component having a backup defined as a distance the transmission component can move from a first point at which further movement in the open direction will cause the window to begin moving in the open direction, and a second point at which further movement in the closed direction will cause the window to begin moving in the closed direction.

Abstract: Medical devices and methods of use thereof are described. The device may include a body having a housing that defines a lumen, a piston within the housing, and an actuator operably coupled to the piston, wherein the piston is movable along the lumen by operating the actuator. The device also may include a cartridge insertable into the body and/or a flexible fitting configured for direct application to an eye of a subject.

Abstract: Method for manufacturing a dental expander having a first attachment member intended to be fixed to a first fixation tooth of a patient and an active member rigidly connected to the first attachment member. The method includes: a) generating a three-dimensional digital model of a dental arch having the fixation tooth or “arch model”; b) using the arch model as a basis for generating: a three-dimensional digital model of the first attachment member, wherein the model of the first attachment member that has an inner surface that substantially reproduces a part of the surface of the first fixation tooth, and/or a three-dimensional digital model of the active member; and c) using the model of the first attachment member as a basis for manufacturing the first attachment member and/or using the model of the active member as a basis for generating the active member.

Abstract: Medical devices and methods of use thereof are described. The device may include a body having a housing that defines a lumen, a piston within the housing, and an actuator operably coupled to the piston, wherein the piston is movable along the lumen by operating the actuator. The device also may include a cartridge insertable into the body and/or a flexible fitting configured for direct application to an eye of a subject.