Patents Assigned to D
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Publication number: 20200386088Abstract: Method to enhance the recovery of oil from an oil field, comprising: applying heat to a colloidal hydrocarbonic medium that comprises hydrocarbon chains; and applying pressure waves having a predetermined frequency and intensity to hydrocarbon chains, in order to crack hydrocarbon chains into relatively shorter hydrocarbon chains. Optionally: applying heat may comprise applying steam; the pressure waves may be applied directly or indirectly to hydrocarbon chains to be cracked; applying pressure waves may be performed within the oil field, by use of an Activator within or outside of the oil field; applying pressure waves may be performed within the oil field; applying pressure waves may be performed by use of a rotor situated in a housing pervaded by the colloidal hydrocarbonic medium.Type: ApplicationFiled: June 5, 2020Publication date: December 10, 2020Applicant: Innovative Crude Technologies Inc. d/b/a ICTInventors: Ruediger Uwe NUERK, Joseph M. LAURA
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Publication number: 20200385341Abstract: This invention relates to compounds that are useful as inhibitors, in particular as inhibitors of Cathepsin K (CatK), and to a method of inhibiting cathepsin activity, comprising administering a compound or formulation comprising a compound according to the invention.Type: ApplicationFiled: December 5, 2018Publication date: December 10, 2020Applicant: ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LUMC)Inventors: Huib OVAA, Maria Wilhelmina Elisabeth MONS, Stan VAN BOECKEL
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Publication number: 20200385675Abstract: The invention provides a method for separating a mammal early follicle to obtain a single oocyte and a single granulocyte thereof. The method is capable of separating a mammal early follicle to obtain an active single oocyte and a corresponding granulocyte thereof. The invention further provides a kit for obtaining a single oocyte and a single granulocyte thereof from a mammal early follicle.Type: ApplicationFiled: July 3, 2017Publication date: December 10, 2020Applicant: SDIVF R&D CENTRE LIMITEDInventors: Zijiang CHEN, Jinlong MA, Yue LV, Han ZHAO, Gang LU
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Publication number: 20200383891Abstract: The present invention relates to a deodorant composition comprising an oxazolidine- or, a thiazolidine-carboxylic acid compound, a cosmetic carrier and optionally a fragrance. The invention also relates to a manufacturing process for the deodorant composition, a method of treating malodour and a method of screening deodorant actives as well as inhibiting a Staphylococcus hominis C-S ?-lyase.Type: ApplicationFiled: December 12, 2018Publication date: December 10, 2020Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Diana Sheila Cox, Alexander Gordon JAMES, Mrinalini Jayant PURANIK, David William THORNTHWAITE, Jason Richard WILLIAMS
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Patent number: 10859577Abstract: The present invention is in the technical field of breast cancer management, and more particularly relates to the diagnosis and/or prognosing of triple-negative breast cancer (TNBC). The invention is more particularly based on the finding that specific biomarkers are abberantly expressed in patients suffering from a triple-negative breast cancer recurrence, and are highly related to the aggressiveness of this disease, and thus to survival of said patient.Type: GrantFiled: November 24, 2014Date of Patent: December 8, 2020Assignees: Institut de Cancerologie de L'Ouest, Universite D'Angers, Institut National de la Sante et de la Recherche Medicale (INSERM)Inventors: Catherine Guette, Mario Campone, Olivier Coqueret, Benjamin Barre
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Patent number: 10858917Abstract: The present invention discloses an expandable liner hanger system comprising a central pipe and an expandable pipe, with an expansion cone provided therebetween the central pipe and expandable pipe in a way that the expansion cone is movable along the central pipe, so that the expandable pipe is expanded; wherein, the expansion cone comprises an expansion cone seat move along the central pipe, and an expansion cone sleeve fitted over the expansion cone seat, the connection between the expansion cone seat and the expansion cone sleeve is configured in a way that the expansion cone sleeve can move upward together with the expansion cone seat along the central pipe so that the expandable pipe is expanded, and the central pipe can drive the expansion cone seat to disengage from the expansion cone sleeve.Type: GrantFiled: April 19, 2019Date of Patent: December 8, 2020Assignee: CNPC ENGINEERING TECHNOLOGY R&D COMPANY LIMITEDInventors: Quanli Zhang, Hongwei Yin, Wanjun Li, Huijuan Guo, Guojun Liu, Binggui Xu, Gang Chen, Yingjie Zhu, Gang Wang, Shaohua Zhou, Zhitong Liu, Yongliang Yu, Mingmin He, Tao Jia, Jianli Wang, Mingjie Lv, Fei He
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Patent number: 10859198Abstract: A foot for household appliance and a household appliance are provided. The foot includes: a hydraulic plate; a sheath, fixedly connected with the hydraulic plate; an adjustable foot, arranged in the sheath and capable of axially moving relative to the sheath, an accommodating chamber is formed by the hydraulic plate, the sheath and the adjustable foot; a hydraulic medium, arranged in the accommodating chamber, and the hydraulic medium is compressed or expanded depending on pressure changes to drive the adjustable foot to move axially in the sheath for leveling. At least two feet are communicated with each other to allow the hydraulic medium to flow between the feet. A liquid flowing passage for allowing the hydraulic medium to flow is arranged in the hydraulic plate. A control device for controlling the liquid flowing passage to open or close is arranged on at least one of the feet.Type: GrantFiled: June 29, 2017Date of Patent: December 8, 2020Assignees: QINGDAO HAIER WASHING MACHINE CO., LTD., QINGDAO HAIER SMART TECHNOLOGY R&D CO., LTD.Inventor: Zhiqiang Zhao
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Patent number: 10857049Abstract: An armchair comprising a seat chassis supported on a support chassis by a pair of support columns, a chair back structure pivotally attached to a rear end of the seat chassis and to the support chassis, and a leg support structure pivotally attached to a front end of the seat chassis and connected to a beam, wherein the beam is attached the chair back structure. A first actuating device is mounted to the chair back, where a protracting end of the first actuating device is connected to the seat chassis. The armchair further comprises a second actuating device mounted to the support chassis, a footrest connected to a protracting end of the second actuating device, a third actuating device attached to the seat chassis, and a seating structure connected to a protracting end of the third actuating device and mounted above the seat chassis, wherein the seating structure includes an operative position projecting upwards and forwards by the third actuating device at a tilting angle from the seat chassis.Type: GrantFiled: February 18, 2019Date of Patent: December 8, 2020Assignee: J&D Furniture LLCInventors: Janet Schwartz Feldman, Derek Feldman, Aviv Rottenberg, David Yassaf, Gilad Davidi, Alex Padwa
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Patent number: 10856650Abstract: There is described a scratch-free snow removal tool comprising a flexible blade presenting a sweeping surface extending in a plane. The flexible blade defines a blade edge which is continuous and can be made of silicone or TPE. The blade support is more rigid than the flexible blade. A plurality of fingers is provided, which are more rigid than the flexible blade and extend in the plane of the sweeping surface, from the blade support toward the blade edge without reaching the blade edge.Type: GrantFiled: April 2, 2019Date of Patent: December 8, 2020Assignee: André Lafleur RD&D Inc.Inventor: Andre Lafleur
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Patent number: 10858124Abstract: The invention relates to a method for transferring a space payload from a first orbit to a second orbit. Said method is characterized in that the space payload, moving about the first orbit, is attached to a removable orbital towing assistance device including at least one fuel pouch. Said method includes the steps of: —attaching (E1) an orbital transfer vehicle to the removable orbital towing assistance device; and —transferring (E2) the space payload and the removable orbital towing assistance device to the second orbit by means of the orbital transfer vehicle. The invention also relates to a removable orbital towing assistance device intended for a space payload and an orbital transfer vehicle and enabling direct supply of fuel to the vehicle and/or the space payload.Type: GrantFiled: April 3, 2015Date of Patent: December 8, 2020Assignee: CENTRE NATIONAL D'ETUDES SPATIALESInventor: Pascal Bultel
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Patent number: 10858306Abstract: The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.Type: GrantFiled: April 9, 2020Date of Patent: December 8, 2020Assignees: INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NANTES, UNIVERSITE D'ANGERS, THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICESInventors: François Guerard, Jean-François Gestin, Martin W. Brechbiel, Yong-Sok Lee
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Patent number: 10861425Abstract: A snare system for use with a drum has a snare assembly with snares extended longitudinally between opposite end plates. The end plates define a slot from a top surface to a bottom surface with obliquely extending walls. Two connectors, each with a strap carrying a latch member, are attached to opposite sides of the drum via its strap with latch member within the drum rim. Each latch member includes a flange with oblique configuration complimentary to the oblique slot in the end plates. The snare assembly is attached via sliding engagement of the respective flanges into the respective slots with the surfaces of each in surface-to-surface contact so that the connectors maintain the snare assembly attached to the drum. The snare assembly is removable quickly by reverse sliding of the flanges from the slots to interchange with a different snare assembly having end plates with a common configuration.Type: GrantFiled: June 24, 2019Date of Patent: December 8, 2020Assignee: D'Addario & Company, Inc.Inventors: James D'Addario, Richard Ned Steinberger, Richard Stillwell
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Patent number: 10861582Abstract: A method for implementing an adapted patient care for an individual suffering from liver fibrosis after assessing liver fibrosis progression in the individual, and thus determining whether the individual is a slow, medium or fast fibroser. Also, a method for treating an individual suffering from liver fibrosis and identified as a fast fibroser, which includes the steps of identifying the individual as a fast fibroser by assessing fibrosis progression and treating the individual by administering without delay at least one therapeutic agent for treating liver fibrosis, or for treating the underlying cause responsible for liver fibrosis, or both.Type: GrantFiled: May 30, 2017Date of Patent: December 8, 2020Assignees: CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS, UNIVERSITÉ D'ANGERSInventor: Paul Cales
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Patent number: 10857912Abstract: An adjustment mechanism the includes a screw, a support having first and second transverse walls perpendicular to the screw, a casing having first and second end faces arranged facing the first and second transverse walls and having a nut housing which opens in opposite first and second openings, a first elastomer pad interposed between the first transverse wall of the support and the first end face of the casing, a second elastomer pad interposed between the second transverse wall of the support and the second end face of the casing, a nut screwed onto the screw, a bearing engaged in the second opening of the casing and traversed by the screw. The nut is in rigid abutment against the casing in the direction of the first opening and the bearing is in elastic abutment against the second elastomer pad.Type: GrantFiled: September 17, 2018Date of Patent: December 8, 2020Assignee: FAURECIA SIÈGES D'AUTOMOBILEInventor: Jean-Noel Rey
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Patent number: 10856574Abstract: Machine and method for producing a substantially cylindrical article, which comprises a tubular body, a container element, arranged in the area of one end of the tubular element, a heat generating element, partially housed inside the container element, and loose material for generating flavour; in use, the loose material is inserted into the container element, vertically oriented, and the heat generating element is partially inserted into the container element by being moved downwards, so as to obtain a combined element; subsequently, the combined element is at least partially inserted into the tubular body.Type: GrantFiled: October 19, 2016Date of Patent: December 8, 2020Assignee: G.D SOCIETA' PER AZIONIInventors: Roberto Claudio Franco Ghiotti, Luca Federici
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Patent number: 10858268Abstract: The invention relates to a system for applying a superimposed time-varying frequency electromagnetic wave to a target object or a target region that is formed by the target object and a medium surrounding the target object, comprising a device for generating a superimposed time-varying frequency electromagnetic wave where the time-varying AC wave is riding on the predefined DC bias voltage. When applied to the object or region, the superimposed time-varying frequency electromagnetic wave is able to induce a flow of ionic current having a DC component traveling in a pulsating and time-varying manner in the target object and/or in the medium and effect induced vibration of electrons and molecules of the target object and the medium. The invention also relates to a method applying a superimposed time-varying frequency electromagnetic wave to a target object or a target region.Type: GrantFiled: July 29, 2015Date of Patent: December 8, 2020Assignee: Semb-Eco R&D Pte LtdInventors: Hwee Hong Chew, Poh Kwee Ong
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Patent number: 10858452Abstract: The present invention relates to specific interleukin-15 (IL-15) antagonist polypeptides and uses thereof for the treatment of inflammatory and auto-immune diseases. In particular, the present invention relates to a specific interleukin-15 (IL-15) antagonist polypeptide comprising i) a IL15-Ralpha sushi-containing polypeptide comprising an amino acid sequence having at least 80% of identity with the amino acid sequence of SEQ ID NO:1 ii) a linker and iii) an IL-polypeptide comprising the amino acid sequence having at least at least 80% of identity with the amino acid sequence of SEQ ID NO:4 provided that the glutamine (Q) residue at position 108 is mutated.Type: GrantFiled: September 15, 2016Date of Patent: December 8, 2020Assignees: Insitut National de la Sante et de la Recherche Medicale (INSERM), Universite de Nantes, Universite d'Angers, Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire de NantesInventors: Erwan Mortier, Dihia Meghnem, Sebastien Morisseau, Yannick Jacques
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Publication number: 20200376010Abstract: A nutraceutical and/or pharmaceutical composition designed to stimulate the production of type 2 beta-defensins. The composition includes as a sole active ingredient a gluco-oligosaccharide presenting the following basic oligomeric structure: for the treatment of intestinal inflammations in the quantity of 0.5 to 10 g. Application to the treatment of functional colopathy.Type: ApplicationFiled: April 26, 2018Publication date: December 3, 2020Applicant: USINES CHIMIQUES D'IVRY LA BATAILLEInventors: Thibaut SAGUET, Laurent LASSALLE, Jean-Luc PHILBE, Florent YVERGNAUX
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Publication number: 20200375970Abstract: Disclosed is a therapeutic agent for hepatocellular carcinoma, comprising 5-((2-(4-(2-hydroxyethyl)piperidin-4-yl)benzamide)pyridin-4-yl)oxy)-6-(2-methoxyethoxy)-N-methyl-1H-indole-1-carboxamide or a pharmacologically acceptable salt thereof.Type: ApplicationFiled: March 26, 2019Publication date: December 3, 2020Applicant: Eisai R&D Management Co., Ltd.Inventors: Atsumi Yamaguchi, Hajime Shimizu, Satoshi Goda, Saori Miyano
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Publication number: 20200378950Abstract: A method of characterizing the protein O-GlcNAcylation site-specificity of an antibody. A method of detecting or quantifying the expression of site-specific O-GlcNAcylated proteins expressed in cells and biological samples. A method of diagnosing cancer in a host based on the cellular expression of site-specific O-GlcNAcylated proteins. A method of screening anti-cancer compounds according to their ability to increase a level O-GlcNAcylation of oncogene or tumor suppressor proteins. Methods of treating cancer in an animal host by administering compounds that increase a level of O-GlcNAcylated c-myc or p53 in cancer cells. A method of distinguishing subclasses of pancreatic cancer according to the sensitivity of pancreatic cancer cells to an imidazole derivative, and a method of personalized pancreatic cancer treatment delivered according to the sensitivity subclasses.Type: ApplicationFiled: May 27, 2019Publication date: December 3, 2020Applicant: Detroit R & D, Inc.Inventors: Hyesook Kim, So Hee Kim