Abstract: The invention discloses an improved GNSS receiver which determines a location of the receiver by combining a first location determined either from the standard PVT and/or from a positioning aid like a map matching algorithm, inertial navigation system, WiFi localization system or other, and a second location determined by integrating the velocity from the standard PVT. The combination is based on a weighting of the error budgets of the first position and the second location. The improved receiver is preferably based on a standard receiver with an add-on software module which receives and processes data transmitted from the standard receiver by, for example, NMEA messages. The improved receiver allows a determination of a more precise and smoother trajectory in a simple way.

Abstract: Vapor generation and distribution devices, systems, and methods. An exemplary system of the present disclosure comprises a vapor generation system configured to volatilize or vaporize liquid chemical within a tank as volatilized or vaporized chemical, and a vapor distribution system configured to receive the volatilized or vaporized chemical from the vapor generation system and distribute the volatilized or vaporized chemical through a distribution conduit coupled to the second air flow generator.

Abstract: The invention provides two crystalline freebase forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester. The invention also provides pharmaceutical compositions comprising the crystalline freebase or prepared using the crystalline freebases; processes and intermediates for preparing the crystalline freebases; and methods of using the crystalline freebases to treat a pulmonary disorder.

Abstract: Disclosed embodiments include apparatuses, systems, and methods for positioning electrodes within a body. In an illustrative embodiment, a control handle is selectively engageable with primary and secondary actuators respectively coupled with primary and secondary electrodes. At a first position, the primary and secondary actuators are movably engaged to move in concert to a second position where distal ends of the electrodes extend into a target region. At the second position, the control handle is engaged with the secondary actuator and movable independently of the primary actuator in a first direction to a third position where the distal end of the secondary electrode extends beyond the distal end of the primary electrode. At the third position, the control handle is movably engaged with the primary actuator and movable independently of the secondary actuator in a second direction to a fourth position to partially retract the distal end of the primary electrode.

Abstract: An implanted electrical signal generator delivers a novel exogenous electrical signal to a vagus nerve of a patient. The vagus nerve conducts action potentials originating in the heart and lungs to various structures of the brain, thereby eliciting a vagal evoked potential in those structures. The exogenous electrical signal simulates and/or augments the endogenous afferent activity originating from the heart and/or lungs of the patient, thereby enhancing the vagal evoked potential in the various structures of the brain. The exogenous electrical signal includes a series of electrical pulses organized or patterned into a series of microbursts including 2 to 20 pulses each. No pulses are sent between the microbursts. Each of the microbursts may be synchronized with the QRS wave portion of an ECG. The enhanced vagal evoked potential in the various structures of the brain may be used to treat various medical conditions including epilepsy and depression.

Abstract: Systems, devices, articles, methods, and techniques for advancing quantum computing by removing unwanted interactions in one or more quantum processor. One approach includes creating an updated plurality of programmable parameters based at least in part on a received value for the characteristic magnetic susceptibility of the qubit in the at least one quantum processor, and returning the updated plurality of programmable parameters. Examples programmable parameters include local biases, and coupling values characterizing the problem Hamilton.

Abstract: Provided is a multichannel pipette whose number of channels can be arbitrarily set and managed to improve usability of the multichannel pipette and improve productivity, quality control, and maintainability in a research site. A multichannel pipette includes a pipette main body, a lower part attached to a lower end portion of the pipette main body, and a plurality of chip holder units housed inside the lower part, wherein each of the chip holder units has a connecting portion attachable to and removable from any of a plurality of to-be-connected portions provided in a unit case inside the lower part, and each of the chip holder units is attachable to and removable from the lower part.

Abstract: Generate an automorphism of the problem graph, determine an embedding of the automorphism to the hardware graph and modify the embedding of the problem graph into the hardware graph to correspond to the embedding of the automorphism to the hardware graph. Determine an upper-bound on the required chain strength. Calibrate and record properties of the component of a quantum processor with a digital processor, query the digital processor for a range of properties. Generate a bit mask and change the sign of the bias of individual qubits according to the bit mask before submitting a problem to a quantum processor, apply the same bit mask to the bit result. Generate a second set of parameters of a quantum processor from a first set of parameters via a genetic algorithm.

Abstract: An industrial process analysis system is disclosed The system comprises a process data connection device for the acquisition of process data from process data source, an input system for receiving at least one search instruction, an indexing system for indexing the process data to create a set of indexed process data a data processing device for processing the at least one search instruction to create a search parameter set and comparing distances of members of the search parameter set with corresponding members of the indexed process data to obtain a similarity value; and an output device to display results based on the similarity value.

Abstract: A server and a number of client devices are connected via a network. Interactive objects are initiated in one of the client devices and delivered to any number of other client devices over the network. Real-time interactions between the object sender and the object receiver(s) can then be engaged using event-triggering mechanisms built into the client devices and applied onto the objects, and be coordinated by a coordinating module in the server. The interactive objects may carry instructions for event-triggered loading, activating and execution of functional widgets, such as workflows or collaborations, stored in the same server or elsewhere on the network. Once loaded in a client device, a widget needs not to be reloaded upon further use. Furthermore, the coordinating module may be linked to a machine-learning module in the same server or elsewhere on the network.

Abstract: The present invention relates to pharmaceutical compositions comprising inhibitor(s) of human histone methyltransferase EZH2, and methods of cancer therapy using the EZH2 inhibitor(s).

Abstract: An antenna array includes a plurality of linear electromagnetic resonators having longitudinal axes oriented parallel to one another and not aligned, and at least one decoupling device arranged between two the linear electromagnetic resonators, wherein the decoupling device comprises a plurality of open-loop electromagnetic resonators that are matched to a frequency located in the bandwidth of the two the adjacent linear electromagnetic resonators, that are electrically insulated and that are arranged in a plurality of planes that are not parallel to a plane containing the longitudinal axes of the two the linear electromagnetic resonators. Nuclear magnetic resonance imaging apparatus comprising such an antenna array is also provided.

Abstract: A stocking assistant robot includes a base plate, one or more wheels coupled to the base plate, a first support coupled to the base plate, and a second support coupled to the base plate, wherein the first support is configured to move perpendicular to the base plate and the second support is configured to move perpendicular to the base plate. The stocking assistant robot also includes a first actuator configured to move the first support perpendicular to the base plate, and a second actuator configured to move the second support perpendicular to the base plate. The stocking assistant robot identifies an item, determines a stock location based on the identified item, operates one or more electric motors coupled to the one or more wheels based on the stock location, and moves the first support or the second support perpendicular to the base plate based on the stock location.

Abstract: A headrest assembly for a vehicle seat, that is height-adjustable along an adjustment direction. The headrest assembly includes a pin adapted to be fixed to a seat backrest and extending along the adjustment direction, an adjustment plate integrally secured to the one pin, and a supporting structure adapted to support a user's head, mounted so as to be adjustable in translation on the adjustment plate along the adjustment direction. The pin is covered by a covering portion. The covering portion and the adjustment plate are made of plastic material overmolded on the pin.

Abstract: An electrolytic cell for generating hydrogen through the electrolysis of water, including an anodic compartment and a cathodic compartment separated by a solid polymeric electrolyte alkaline membrane. The anodic compartment includes a positive electrode or anode at least partially submerged in a layer of water, and the cathodic compartment includes a negative electrode or cathode. The cell is arranged between a first closing plate and a second closing plate. A tie-rod, provided in the central portion of the first closing plate, passes through the first closing plate, the cell and the second closing plate. A central collector for conveying the hydrogen generated in the cathodic compartment is arranged coaxially to the tie-rod and is in communication with the cathodic compartment through an opening formed in the tie-rod.

Abstract: An alert notification device includes a plurality of devices working together as a whole configured to capture sound events in a restricted surrounding environment being monitored by a user with hearing disability, wherein the alert notification device includes a portable output device configured to execute an alert notification application that analyses at least one match indicator signal received by output device itself, a source signal captured by a resource or a third-party application executed in output device, and, based on an alert notification profile selected by the user using the alert notification application itself and produces, by means of portable output device's own resources, an alert notification signal that is seasonally and visually adapted for the user.

Abstract: A panel assembly that is configured to be secured to a frame that includes a panel having a top and a bottom, a first bracket assembly and a second bracket assembly. The first bracket assembly includes a first pivot member and a first bracket. One of the first bracket and first pivot member is secured to the panel and the other is configured to be secured to the frame. The first bracket includes a slot defined therein that includes a throat and a pivot opening. The throat is defined between first and second throat surfaces and the throat is narrower than the pivot opening. The second bracket assembly includes a second pivot member and a second bracket. One of the second bracket and second pivot member is secured to the panel and the other is configured to be secured to the frame. The second bracket includes a pivot opening.

Abstract: The present invention relates to a process for purifying caprolactam from solutions of crude caprolactam by a direct treatment with one or more alkaline compounds of polyvalent metals, preferably bivalent and trivalent, without resorting to organic solvent extraction as used in the usual purification process. A further subject of the present invention is a facility devoid of a unit for organic solvent extraction and designed to carry out the caprolactam purification process described herein.

Abstract: Provided herein are compounds useful for the treatment of cancer.