Abstract: The invention features methods of using SFGFR3 polypeptides to treat abnormal visceral fat deposition and the conditions associated with abnormal visceral fat deposition.
Type:
Application
Filed:
September 20, 2018
Publication date:
September 24, 2020
Applicants:
Pfizer Inc., Université Côte d'Azur, INSERM (Institut National de la Santé et de la Recherche Médicale), Centre National de la Recherche Scientifique
Abstract: Apparatus and methods are described for use with an output device (34), and a blood sample (12) that was drawn from a subject. A microscope system (10) acquires first and second images of the blood sample at respective times. A computer processor (28) determines whether, between acquisitions of the first and second images, there was relative motion between at least one erythrocyte within the sample and at least one entity within the sample, by comparing the first and second images to one another. At least partially in response thereto, the computer processor determines whether the entity is an extra-erythrocytic or an intra-erythrocytic entity, and generates an output on the output device, at least partially in response thereto. Other applications are also described.
Type:
Application
Filed:
March 23, 2017
Publication date:
September 24, 2020
Applicant:
S.D. Sight Diagnostics Ltd.
Inventors:
Yochay Shlomo ESHEL, Arnon HOURI YAFIN, Joseph Joel POLLAK, Neta BACHAR, Annael MARCIANO, Sarah LEVY SCHREIER
Abstract: Existing content such as books are reorganized and condensed as electronic books for display on a mobile computing device. The electronic books have a hierarchical structure. A user interacts with the content of the book by way of a touch screen of the mobile computing device. The navigation may be non-linear in nature and the book is reconstructed as a set of primary ideas, supporting ideas, stacks of cards for the supporting ideas, and individual cards comprising elements and commentary from or about the book.
Abstract: Methods and combination therapies for treating, preventing, and/or delaying the onset and/or development of Alzheimer's disease using an anti-A? protofibril antibody (such as, for example, BAN2401) and N-[3-((4aS,5R,7aS)-2-amino-5-methyl-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl]-5-difluoromethylpyrazine-2-carboxamide and/or a pharmaceutically acceptable salt thereof (Compound X) are provided.
Abstract: A washing machine comprises a cabinet, a washing drum rotatably arranged in the cabinet, wherein the washing drum is a water holding drum to accommodate washing water, a water drainage channel which discharges water from top to bottom is arranged at an inner side of a peripheral wall of the washing drum, an upper end of the water drainage channel communicates with the inside of a washing drum, and a lower end communicates with the outside of the washing drum. The water drainage channel comprises a water channel casing and at least part of a washing drum wall, and one side, facing the washing drum wall, of the water channel casing is provided with a cut-through groove, the water channel casing is fastened on the washing drum wall, and forms a water flow channel together with the washing drum wall.
Abstract: A nickel-based superalloy comprises, in percentages by mass, 4.0 to 5.5% rhenium, 3.5 to 12.5% cobalt, 0.30 to 1.50% molybdenum, 3.5 to 5.5% chromium, 3.5 to 5.5% tungsten, 4.5 to 6.0% aluminum, 0.35 to 1.50% titanium, 8.0 to 10.5% tantalum, 0.15 to 0.30% hafnium, 0.05 to 0.15% silicon, the balance being nickel and unavoidable impurities. A single-crystal blade comprises such an alloy and a turbomachine comprising such a blade.
Type:
Application
Filed:
November 14, 2018
Publication date:
September 24, 2020
Applicants:
SAFRAN, OFFICE NATIONAL D'ETUDES ET DE RECHERCHES AEROSPATIALES
Inventors:
Jérémy RAME, Virginie JAQUET, Joël DELAUTRE, Jean-Yves GUEDOU, Pierre CARON, Odile LAVIGNE, Didier LOCQ, Mikael PERRUT
Abstract: A seat panel for assembly into a rear surface of a seat assembly includes a light assembly which generates task lighting directed to a task area and of sufficient brightness to be useful in performing a task within the task area. The light assembly is selectively actuable to emit light through an aperture defined by the seat panel in a defined light pattern to illuminate a recessed space in the seat panel. The seat assembly when configured as a forward seat assembly of a vehicle provides task lighting for a passenger seated rearward of the forward seat assembly, to illuminate a task area which can include one or more of the exterior surface of the seat panel, a leg space between the forward seat assembly and the passenger's seat assembly, and/or a seat space generally including a portion of the upper leg and/or lap area of the passenger.
Abstract: A device for measuring condensation and/or advance of corrosion of a conduit includes an insulator extending around the conduit; a first conductor and a second conductor which are arranged such that at least a portion of the insulator lies between the conduit and the first conductor and the second conductor, such that the first conductor forms a first pole of a capacitor, the second conductor forms a second pole of the capacitor, and the portion therebetween comprises a capacitive coupling between the first pole and the second pole. At least one measuring instrument is configured to determine a value which is representative of the capacitive coupling.
Abstract: The invention discloses a receiver of GNSS positioning signals which has embedded computer logic to select between a first operating mode, which uses all available frequencies, and a second operating mode, which uses only part of the available frequencies but in combination with available correction data. The selection is based on a comparison of an index of quality of reception at the receiver and a computed or predicted precision/confidence level of the corrections. A plurality of corrections types are possible, including a type using a local model and a type using collaborative corrections. In some embodiments, a selection and/or a combination of a plurality of local models may be made to optimize the accuracy of the corrections.
Type:
Grant
Filed:
June 17, 2016
Date of Patent:
September 22, 2020
Assignee:
CENTRE NATIONAL D'ETUDES SPATIALES
Inventors:
Sébastien Rougerie, Marion Roudier, Lionel Ries, Laurent Lestarquit
Abstract: A method of treating an eye of a patient may include positioning an expandable strut structure within at least one of an internal carotid artery, an ophthalmic artery, or an ostium at a junction between the internal carotid artery and the ophthalmic artery. Additionally, the method may include directing blood flow towards the ophthalmic artery via a diverter element associated with the expandable strut structure.
Type:
Grant
Filed:
October 4, 2018
Date of Patent:
September 22, 2020
Assignee:
J.D. Franco & Co., LLC
Inventors:
Robert Vidlund, Michael Calhoun, Jeff Franco
Abstract: A system and method for implanting and stabilizing spinal cord stimulators in an epidural space of the spinal column of a patient to prevent or limit axial movement of the stimulators once implanted in the epidural space. The system includes a drill assembly, a guide wire assembly, and a guide wire receiver. The drill assembly includes a cannula, a drill for creating access points in the patient's spinal column for implanting the stimulators, and an incremental drill adjuster for drilling into the patient's lamina a pre-set, discrete distance. The guide wire assembly includes a hollowed guide wire sleeve, a guide wire housed within the sleeve, and a magnet disposed on a proximal end of the guide wire assembly. The guide wire receiver includes a scoop for receiving and catching the magnet to assist in feeding the stimulators through the epidural space.
Abstract: Some embodiments are directed to an analysis device for board sports, intended to be secured to a board, such as a surfboard or ski, at the interface with the user. The device includes: a force sensor designed to capture one or more forces generated by the user on the board; a position and motion sensor designed to capture the position, speed and acceleration of the board in space; and a processing unit or processor connected to the force sensor and to the position and motion sensor and designed to synchronize and process the data from the sensors.
Type:
Grant
Filed:
June 29, 2016
Date of Patent:
September 22, 2020
Assignees:
UNIVERSITÉ DE BOURDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ÉCOLE NATIONAL SUPÉRIEURE D'ARTS ET MÉTIERS (ENSAM), AMVALOR
Inventors:
Kévin Lestrade, Jean-Luc Barou, Philippe Viot, Sandra Guérard, Patrick Lanusse
Abstract: A handle attachment assembly that includes first and second insert members, and a handle assembly that includes a cover and a main body portion. The main body portion includes a handle portion and first and second attachment portions extending from the handle portion. The cover is removably connected to the main body portion and the main body portion and the cover cooperate to define a handle interior. The first and second attachment portions include first and second attachment members, respectively. The first attachment portion and the first insert member are secured together by a first fastener, and the second attachment portion and the second insert member are secured together by a second fastener.
Type:
Grant
Filed:
November 28, 2018
Date of Patent:
September 22, 2020
Assignee:
C&D ZODIAC, INC.
Inventors:
Raul Rogel, Joel Anthony Vizarra, Ajay Hari, Francisco Palafox
Abstract: A compound multi effect distillation (MED) system of integrated backward and forward fed MED systems. Heated concentrate from the hottest effect of the backward fed MED system is delivered as feed to the hottest effect in the forward fed MED system, to generate a more concentrated brine than possible using any of the systems alone. Furthermore, coupling the systems creates additional operational advantages and increases distillation efficiency.
Type:
Grant
Filed:
January 15, 2019
Date of Patent:
September 22, 2020
Assignee:
I.D.E. TECHNOLOGIES LTD
Inventors:
Yaniv Schmidt, Joseph Newman, Herman Weiss
Abstract: The invention relates to a cap (17) which is configured to be assembled with a terminal segment (9) of a windscreen wiper arm (5) which is configured to be connected to a windscreen wiper (3), said terminal segment (19having a longitudinal end (11) bearing a transverse pin (13) which is configured to define a pivot axis of the windscreen wiper (3), the cap (17) comprising: an upper part (171) which is configured to cover the terminal segment (9) of the windscreen wiper arm (5) in the assembled state of the cap (17) on said terminal segment (9), a lower part (173), and at least one fixing means (23) which is configured to cooperate with the transverse pin (13). According to the invention, the lower part (173) of the cap (17) comprises at least one support means (19) which is produced integrally with the cap (17) and which is configured to cooperate with the terminal segment (9) of the windscreen wiper arm (5) for the assembly of the cap (17) with the terminal segment (9).
Abstract: An example method for making a reticle includes providing an assembly. The assembly includes an extreme ultraviolet mirror and a cavity overlaying at least a bottom part of the extreme ultraviolet mirror. The method also includes at least partially filling the cavity with an extreme ultraviolet absorbing structure that includes a metallic material that includes an element selected from Ni, Co, Sb, Ag, In, and Sn, by forming the extreme ultraviolet absorbing structure selectively in the cavity.
Type:
Grant
Filed:
September 6, 2018
Date of Patent:
September 22, 2020
Assignees:
IMEC VZW, KATHOLIEKE UNIVERSITEIT LEUVEN, KU LEUVEN R&D
Inventors:
Boon Teik Chan, Kim Vu Luong, Vicky Philipsen, Efrain Altamirano Sanchez, Kevin Vandersmissen
Abstract: Methods for embedding photocatalytic titanium dioxide in asphalt surfaces to reduce pollutants via photocatalytic reactions include applying an amount of an asphalt surface treatment compound to an upper surface of the asphalt surface, the asphalt surface treatment compound including a mixture of a liquid carrier compound with a titanium dioxide (TiO2) photocatalyst.